Page last updated: 2024-10-22

albendazole and Mansonelliasis

albendazole has been researched along with Mansonelliasis in 6 studies

Mansonelliasis: Infection with nematodes of the genus MANSONELLA. Symptoms include pruritus, headache, and articular swelling.

Research Excerpts

ExcerptRelevanceReference
"The effect of a single dose of ivermectin alone (150-200microg/kg body weight) or in combination with albendazole (total of 400mg) in Mansonella perstans infection was assessed in a randomised, double-blind field trial in two endemic communities in Mukono and Luwero districts of Uganda."2.74A randomised, double-blind field trial of ivermectin alone and in combination with albendazole for the treatment of Mansonella perstans infections in Uganda. ( Asio, SM; Onapa, AW; Simonsen, PE, 2009)
"The effect of coinfection on HIV disease progression varied with species."1.32Helminth infection is not associated with faster progression of HIV disease in coinfected adults in Uganda. ( Brown, M; Elliott, AM; Hughes, P; Kizza, M; Quigley, MA; Rowland, S; Watera, C; Whitworth, JA, 2004)
"Albendazole was not shown to be useful for treatment of Mansonella perstans filariasis."1.28Mansonella perstans filariasis: failure of albendazole treatment. ( Van den Ende, J; Van den Enden, E; Van der Stuyft, P; Van Gompel, A; Vervoort, T, 1992)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Asgeirsson, H1
Harling, A1
Botero-Kleiven, S1
Asio, SM2
Simonsen, PE2
Onapa, AW2
Coulibaly, YI1
Dembele, B1
Diallo, AA1
Lipner, EM1
Doumbia, SS1
Coulibaly, SY1
Konate, S1
Diallo, DA1
Yalcouye, D1
Kubofcik, J1
Doumbo, OK1
Traore, AK1
Keita, AD1
Fay, MP1
Traore, SF1
Nutman, TB1
Klion, AD1
Brown, M1
Kizza, M1
Watera, C1
Quigley, MA1
Rowland, S1
Hughes, P1
Whitworth, JA1
Elliott, AM1
Van den Enden, E1
Van Gompel, A1
Vervoort, T1
Van der Stuyft, P1
Van den Ende, J1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Studies on the Epidemiology and Control of Mansonella Perstans Infection in Uganda[NCT00215280]1,000 participants Interventional2005-11-30Completed
Treatment of Mansonella Perstans Infection in an Area Coendemic for Lymphatic Filariasis: A Pilot Study of the Effects of Doxycycline[NCT00340691]Phase 21,500 participants Interventional2004-12-06Completed
Changes in HIV Viral Load in Patients Undergoing Treatment for Filarial Infection[NCT00344279]1,000 participants (Anticipated)Observational2005-08-08Completed
Can Anthelminthic Treatment Delay the Progression of HIV? Randomised Open-label Trial Testing Presumptive Anthelminthic Treatment on Progression of HIV in ART-naïve HIV-positive Patients in a Rural African Setting With Presumed High Prevalence of Helminth[NCT00817713]295 participants (Actual)Interventional2009-01-31Terminated (stopped due to Terminated prematurely due to recruitment difficulties. Expansion to more study sites not planned.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for albendazole and Mansonelliasis

ArticleYear
A randomised, double-blind field trial of ivermectin alone and in combination with albendazole for the treatment of Mansonella perstans infections in Uganda.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2009, Volume: 103, Issue:3

    Topics: Adolescent; Adult; Aged; Albendazole; Animals; Child; Child, Preschool; Double-Blind Method; Drug Co

2009
Mansonella perstans: safety and efficacy of ivermectin alone, albendazole alone and the two drugs in combination.
    Annals of tropical medicine and parasitology, 2009, Volume: 103, Issue:1

    Topics: Adolescent; Adult; Aged; Albendazole; Animals; Antiparasitic Agents; Child; Drug Combinations; Femal

2009
A randomized trial of doxycycline for Mansonella perstans infection.
    The New England journal of medicine, 2009, Oct-08, Volume: 361, Issue:15

    Topics: Adolescent; Adult; Aged; Albendazole; Animals; Anti-Bacterial Agents; Doxycycline; Drug Therapy, Com

2009

Other Studies

3 other studies available for albendazole and Mansonelliasis

ArticleYear
Successful treatment of 2 imported cases of Mansonella perstans infection.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:5

    Topics: Adult; Albendazole; Animals; Anthelmintics; Doxycycline; Drug Therapy, Combination; Female; Humans;

2017
Helminth infection is not associated with faster progression of HIV disease in coinfected adults in Uganda.
    The Journal of infectious diseases, 2004, Nov-15, Volume: 190, Issue:10

    Topics: Adult; Albendazole; Ancylostomatoidea; Animals; Anthelmintics; CD4 Lymphocyte Count; Disease Progres

2004
Helminth infection is not associated with faster progression of HIV disease in coinfected adults in Uganda.
    The Journal of infectious diseases, 2004, Nov-15, Volume: 190, Issue:10

    Topics: Adult; Albendazole; Ancylostomatoidea; Animals; Anthelmintics; CD4 Lymphocyte Count; Disease Progres

2004
Helminth infection is not associated with faster progression of HIV disease in coinfected adults in Uganda.
    The Journal of infectious diseases, 2004, Nov-15, Volume: 190, Issue:10

    Topics: Adult; Albendazole; Ancylostomatoidea; Animals; Anthelmintics; CD4 Lymphocyte Count; Disease Progres

2004
Helminth infection is not associated with faster progression of HIV disease in coinfected adults in Uganda.
    The Journal of infectious diseases, 2004, Nov-15, Volume: 190, Issue:10

    Topics: Adult; Albendazole; Ancylostomatoidea; Animals; Anthelmintics; CD4 Lymphocyte Count; Disease Progres

2004
Mansonella perstans filariasis: failure of albendazole treatment.
    Annales de la Societe belge de medecine tropicale, 1992, Volume: 72, Issue:3

    Topics: Adult; Aged; Albendazole; Animals; Female; Humans; Male; Mansonelliasis; Microfilariae; Middle Aged;

1992