Page last updated: 2024-10-22

albendazole and Filariasis

albendazole has been researched along with Filariasis in 52 studies

Filariasis: Infections with nematodes of the superfamily FILARIOIDEA. The presence of living worms in the body is mainly asymptomatic but the death of adult worms leads to granulomatous inflammation and permanent fibrosis. Organisms of the genus Elaeophora infect wild elk and domestic sheep causing ischemic necrosis of the brain, blindness, and dermatosis of the face.

Research Excerpts

ExcerptRelevanceReference
"Repeated, single, oral doses of combinations of ivermectin, diethylcarbamazine (DEC) or albendazole are recognized as important tools for parasite control in lymphatic filariasis."9.09Two-year follow-up of the microfilaraemia of asymptomatic brugian filariasis, after treatment with two, annual, single doses of ivermectin, diethylcarbamazine and albendazole, in various combinations. ( Babu, BS; John, A; Kumaraswami, V; Shenoy, RK; Suma, TK, 2000)
"Egypt was one of the first countries to implement a national programme to eliminate lymphatic filariasis based on WHO's strategy of repeated rounds of mass drug administration (MDA) with diethylcarbamazine and albendazole (target population, 2."7.73Effect of yearly mass drug administration with diethylcarbamazine and albendazole on bancroftian filariasis in Egypt: a comprehensive assessment. ( Abd Elaziz, KM; Ahmed, ES; El Setouhy, M; Farid, HA; Helmy, H; Ramzy, RM; Shannon, WD; Weil, GJ, 2006)
"punctulatus vector."5.35The impact of repeated rounds of mass drug administration with diethylcarbamazine plus albendazole on bancroftian filariasis in Papua New Guinea. ( Bockarie, MJ; Kastens, W; Kazura, JW; King, CL; Laney, SJ; Susapu, M; Weil, GJ; Williams, SA, 2008)
"In Africa, albendazole and ivermectin are currently used in combination for annual mass drug administration (MDA) for lymphatic filariasis (LF) elimination."5.20Randomised controlled clinical trial of increased dose and frequency of albendazole and ivermectin on Wuchereria bancrofti microfilarial clearance in northern Malawi. ( Banda, LG; French, N; Horton, J; Koole, O; Ngwira, BM; Phiri, AJ; Piston, WN; Taegtmeyer, M; Tafatatha, TT; Wilson, TP, 2015)
"Repeated, single, oral doses of combinations of ivermectin, diethylcarbamazine (DEC) or albendazole are recognized as important tools for parasite control in lymphatic filariasis."5.09Two-year follow-up of the microfilaraemia of asymptomatic brugian filariasis, after treatment with two, annual, single doses of ivermectin, diethylcarbamazine and albendazole, in various combinations. ( Babu, BS; John, A; Kumaraswami, V; Shenoy, RK; Suma, TK, 2000)
"In India, annual rounds of mass drug administration (MDA) based on diethylcarbamazine and albendazole are used to control filariasis, which is a major public-health problem."3.75Mass drug administration against filariasis in India: perceptions and practices in a rural community in Kerala. ( Aswathy, S; Beteena, K; Leelamoni, K, 2009)
"Currently, annual mass treatments with albendazole (ABZ) plus ivermectin (IVM) or diethylcarbamazine (DEC) are administered under the Global Programme to Eliminate Lymphatic Filariasis (GPELF)."3.74An analysis of the population genetics of potential multi-drug resistance in Wuchereria bancrofti due to combination chemotherapy. ( Basáñez, MG; Churcher, TS; Prichard, RK; Schwab, AE; Schwab, AJ, 2007)
"The Global Program to Eliminate Lymphatic Filariasis has been implemented to reduce human microfilaremia to levels low enough to break the transmission of the disease by using single annual doses of albendazole in combination with diethylcarbamazine or ivermectin."3.73Detection of benzimidazole resistance-associated mutations in the filarial nematode Wuchereria bancrofti and evidence for selection by albendazole and ivermectin combination treatment. ( Boakye, DA; Kyelem, D; Prichard, RK; Schwab, AE, 2005)
"Egypt was one of the first countries to implement a national programme to eliminate lymphatic filariasis based on WHO's strategy of repeated rounds of mass drug administration (MDA) with diethylcarbamazine and albendazole (target population, 2."3.73Effect of yearly mass drug administration with diethylcarbamazine and albendazole on bancroftian filariasis in Egypt: a comprehensive assessment. ( Abd Elaziz, KM; Ahmed, ES; El Setouhy, M; Farid, HA; Helmy, H; Ramzy, RM; Shannon, WD; Weil, GJ, 2006)
"The Global Program for the Elimination of Lymphatic Filariasis (GPELF) intends to achieve its aims through yearly mass treatments with albendazole (ABZ) combined with ivermectin (IVM) or diethylcarbamazine (DEC)."3.73Population genetics of concurrent selection with albendazole and ivermectin or diethylcarbamazine on the possible spread of albendazole resistance in Wuchereria bancrofti. ( Basáñez, MG; Churcher, TS; Prichard, RK; Schwab, AE; Schwab, AJ, 2006)
"Albendazole, anthelmintic benzimidazole (BZ) is being co-administered with an antifilarial drug, diethylcarbamazine (DEC), in lymphatic filariasis (LF) elimination programmes."3.72Detection of codon for amino acid 200 in isotype 1 beta-tubulin gene of Wuchereria bancrofti isolates, implicated in resistance to benzimidazoles in other nematodes. ( Das, PK; Hoti, SL; Subramaniyan, K, 2003)
"These findings suggest that increasing the dosage and frequency of albendazole-ivermectin treatment enhances suppression of microfilariae but that this effect may not be attributable to improved adulticidal activity."2.75Use of high-dose, twice-yearly albendazole and ivermectin to suppress Wuchereria bancrofti microfilarial levels. ( Coulibaly, ME; Coulibaly, SY; Coulibaly, YI; Dembele, B; Diallo, AA; Diaman Keita, A; Dolo, H; Doumbia, SS; Fay, MP; Klion, AD; Konate, S; Nutman, TB; Sanogo, D; Soumaoro, L; Traore, SF, 2010)
"A six-week regimen of doxycycline treatment against filariasis showed amelioration of pathologic conditions of hydrocele patients with active infection."2.74Reduction in levels of plasma vascular endothelial growth factor-A and improvement in hydrocele patients by targeting endosymbiotic Wolbachia sp. in Wuchereria bancrofti with doxycycline. ( Adjei, O; Batsa, L; Debrah, AY; Hoerauf, A; Lawson, B; Mand, S; Marfo-Debrekyei, Y; Pfarr, K; Taylor, M, 2009)
" These data showed no statistically significant difference in the efficacy of the two drug regimens in lowering the microfilaria reservoir, but they support the use of diethylcarbamazine combined with albendazole in mass treatment programs on the basis of greater activity against adult worms."2.73Efficacy of single-dose diethylcarbamazine compared with diethylcarbamazine combined with albendazole against Wuchereria bancrofti infection in Papua New Guinea. ( Alpers, MP; Bockarie, MJ; Hazlett, F; Ibam, I; Kastens, W; Kazura, JW; Tavul, L; Tisch, DJ, 2007)
" A randomized double-blind field trial with a single dose of ivermectin (150-200 microg/kg body weight) alone or in combination with albendazole (400 mg) was subsequently carried out among these children."2.71The effect of single dose ivermectin alone or in combination with albendazole on Wuchereria bancrofti infection in primary school children in Tanzania. ( Dunyo, SK; Magesa, SM; Malecela-Lazaro, MN; Michael, E; Simonsen, PE, 2004)
"Albendazole and DEC/ALB were equally efficacious in treating intestinal helminths and for children with W."2.71Tolerance and efficacy of combined diethylcarbamazine and albendazole for treatment of Wuchereria bancrofti and intestinal helminth infections in Haitian children. ( Beach, MJ; Brissau, JM; Desire, D; Fox, LM; Furness, BW; Haser, JK; Lafontant, J; Lammie, PJ; Milord, MD, 2005)
"Filariasis is a global health problem targeted for elimination."1.48Validation of ultrasound bioimaging to predict worm burden and treatment efficacy in preclinical filariasis drug screening models. ( Archer, J; Gamble, J; Marriott, AE; Murphy, E; Sjoberg, H; Steven, A; Taylor, MJ; Turner, JD; Tyrer, H, 2018)
"punctulatus vector."1.35The impact of repeated rounds of mass drug administration with diethylcarbamazine plus albendazole on bancroftian filariasis in Papua New Guinea. ( Bockarie, MJ; Kastens, W; Kazura, JW; King, CL; Laney, SJ; Susapu, M; Weil, GJ; Williams, SA, 2008)
"Diethylcarbamazine (DEC) has been used for decades in control programs as an effective microfilaricide, although its efficacy in killing adult worms is only around 50% and its direct mode of action is unclear."1.34Comparative analysis of a chemotherapy effect on the cuticular surface of Wuchereria bancrofti adult worms in vivo. ( Dreyer, G; Lanfredi, RM; Lins, R; Norões, J; Oliveira-Menezes, A, 2007)
"A dog infested with Filaroides osleri was dosed with albendazole at 9,5 mg/kg every day for 55 days."1.26The treatment of Filaroides osleri infestation with albendazole. ( Petrick, SW; van Heerden, J, 1980)

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.85)18.7374
1990's4 (7.69)18.2507
2000's29 (55.77)29.6817
2010's17 (32.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adeleke, AA1
Faraj, J1
Mander, J1
Burnett, JR1
Prentice, D1
Turner, JD3
Sharma, R1
Al Jayoussi, G1
Tyrer, HE1
Gamble, J2
Hayward, L1
Priestley, RS1
Murphy, EA1
Davies, J1
Waterhouse, D1
Cook, DAN1
Clare, RH1
Cassidy, A1
Steven, A2
Johnston, KL1
McCall, J1
Ford, L1
Hemingway, J1
Ward, SA1
Taylor, MJ3
Marriott, AE1
Sjoberg, H1
Tyrer, H1
Murphy, E1
Archer, J1
Choi, TW1
Cho, JH1
Ahnn, J1
Song, HO1
Supali, T1
Djuardi, Y1
Bradley, M1
Noordin, R1
Rückert, P1
Fischer, PU1
Talaat, KR1
Babu, S1
Menon, P1
Kumarasamy, N1
Sharma, J1
Arumugam, J1
Dhakshinamurthy, K1
Srinivasan, R1
Poongulali, S1
Gu, W1
Fay, MP2
Swaminathan, S1
Nutman, TB3
Pan, C1
Cai, B1
Wang, L1
Tafatatha, TT1
Ngwira, BM1
Taegtmeyer, M1
Phiri, AJ1
Wilson, TP1
Banda, LG1
Piston, WN1
Koole, O1
Horton, J1
French, N1
Bal, M1
Sahu, PK1
Mandal, N1
Satapathy, AK1
Ranjit, M1
Kar, SK1
De Britto, RL1
Vanamail, P1
Sankari, T1
Vijayalakshmi, G1
Das, LK1
Pani, SP1
Liang, JL1
King, JD1
Ichimori, K1
Handzel, T1
Pa'au, M1
Lammie, PJ3
Weil, GJ4
Kastens, W2
Susapu, M1
Laney, SJ1
Williams, SA1
King, CL1
Kazura, JW3
Bockarie, MJ2
Debrah, AY2
Mand, S2
Marfo-Debrekyei, Y1
Batsa, L1
Pfarr, K2
Lawson, B1
Taylor, M1
Adjei, O2
Hoerauf, A2
El-Shazly, AM1
Saker, TI1
El-Fayoumy, KN1
Aboulmagd, AA1
El-Ghareeb, AS1
Zalouk, TK1
Abdel-Tawab, AH1
Aswathy, S1
Beteena, K1
Leelamoni, K1
Cárdenas, MQ1
Oliveira-Menezes, A2
Lanfredi, RM2
Dembele, B1
Coulibaly, YI2
Dolo, H1
Konate, S1
Coulibaly, SY1
Sanogo, D1
Soumaoro, L1
Coulibaly, ME1
Doumbia, SS1
Diallo, AA1
Traore, SF2
Diaman Keita, A1
Klion, AD2
Tomlow, B1
Rellum, M1
Itoh, M1
Weerasooriya, MV1
Yahathugoda, TC1
Takagi, H1
Samarawickrema, WA1
Nagaoka, F1
Kimura, E1
Serbus, LR1
Landmann, F1
Bray, WM1
White, PM1
Ruybal, J1
Lokey, RS1
Debec, A1
Sullivan, W1
Rajendran, R1
Sunish, IP1
Mani, TR1
Munirathinam, A1
Abdullah, SM1
Augustin, DJ1
Satyanarayana, K1
Abdul-Fattah, MM1
El-Karamany, EM1
El-Gindy, AM1
Nimr, WA1
El-Shamy, MH1
De Silva, NR1
Pathmeswaran, A1
Fernando, SD1
Weerasinghe, CR1
Selvaratnam, RR1
Padmasiri, EA1
Montresor, A1
Hoti, SL1
Subramaniyan, K1
Das, PK1
Keiser, PB1
Keita, F1
Traore, D1
Diallo, A1
Diallo, DA1
Semnani, RT1
Doumbo, OK1
Simonsen, PE1
Magesa, SM1
Dunyo, SK1
Malecela-Lazaro, MN1
Michael, E1
Tippawangkosol, P1
Choochote, W1
Na-Bangchang, K1
Jitpakdi, A1
Pitasawat, B1
Riyong, D1
Sharma, DC1
Khan, MA1
Gaur, RL2
Dixit, S2
Saleemuddin, M1
Murthy, PK2
Farid, HA3
Kamal, SA1
Adham, FK1
Ramzy, RM3
Hammad, RE1
Hassan, MM1
El Setouhy, M2
Fox, LM1
Furness, BW1
Haser, JK1
Desire, D1
Brissau, JM1
Milord, MD1
Lafontant, J1
Beach, MJ2
Schwab, AE3
Boakye, DA1
Kyelem, D1
Prichard, RK3
Helmy, H1
Ahmed, ES1
Abd Elaziz, KM1
Shannon, WD1
Muehlfeld, J1
McGarry, HF1
Churcher, TS2
Schwab, AJ2
Basáñez, MG2
Dreyer, G2
Addiss, D1
Williamson, J1
Norões, J2
Yongyuth, P1
Koyadun, S1
Jaturabundit, N1
Sampuch, A1
Bhumiratana, A1
Sahoo, MK1
Khanna, M1
Singh, S1
Tavul, L1
Ibam, I1
Hazlett, F1
Tisch, DJ1
Alpers, MP1
Lins, R1
Denham, DA1
Liron, DA1
Brandt, E1
van Heerden, J1
Petrick, SW1
Duarte, Z2
Gantier, JC2
Gayral, P2
Addiss, DG1
Streit, TG1
Lutwick, S1
LeConte, FH1
Lafontant, JG1
Hightower, AW1
Sharp, D1
Maher, D1
Ottesen, EA1
Shenoy, RK1
John, A1
Babu, BS1
Suma, TK1
Kumaraswami, V1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Changes in HIV Viral Load in Patients Undergoing Treatment for Filarial Infection[NCT00344279]1,000 participants (Anticipated)Observational2005-08-08Completed
Efficacy of Higher Albendazole and Ivermectin Doses on Wuchereria Bancrofti Microfilarial Clearance in Malawi, Open Label Study[NCT01213576]70 participants (Actual)Interventional2009-01-31Terminated (stopped due to Introduction of National Mass Drug Administration Campaign and failure to identify appropriate participants.)
Alternate Chemotherapy Regimens for the Clearance of W.Bancrofti Infection: Double Blind Randomised Clinical Trial (RCT) to Study the Efficacy of Different Co-administration and Sequential Administration[NCT02005653]Phase 4146 participants (Actual)Interventional2009-02-28Completed
Effect of Concomitant Mansonella Perstans Microfilaremia on Immune Responses Following Single Dose Praziquantel in Subjects With Schistosomiasis: A Pilot Study[NCT02734186]Phase 40 participants (Actual)Interventional2016-04-06Withdrawn
Alternative Chemotherapies for Lymphatic Filariasis (LF) Treatment and Elimination in Africa [Cote d'Ivoire][NCT02974049]189 participants (Actual)Interventional2015-01-31Completed
Effect of Albendazole and Ivermectin Dose on Wuchereria Bancrofti Microfilarial Clearance in Mali: A Randomized, Open Label Study[NCT00339417]Phase 21,000 participants (Anticipated)Interventional2006-02-22Completed
Treatment of Mansonella Perstans Infection in an Area Coendemic for Lymphatic Filariasis: A Pilot Study of the Effects of Doxycycline[NCT00340691]Phase 21,500 participants Interventional2004-12-06Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Achieving Microfilarial Clearance

Microfilaria clearance will be assessed in regard to dosage as well as frequency of treatment. Microfilarial clearance is defined by non-detection of microfilaria in the night blood sample. (NCT01213576)
Timeframe: 12 months

Interventionparticipants (Number)
Albendazole 400mg and Ivermectin 200mcg/kg Annually15
Albendazole 800mg and Ivermectin 400mcg/kg Annually14
Albendazole 400mg and Ivermectin 200mcg/kg Biannually13
Albendazole 800mg and Ivermectin 400mcg /kg Bi-annually17

Number of Participants With Microfilarial Clearance at 24 Months of Follow up

Microfilaria will be detected using the nucleopore filtration technique and analysed according to the respective treatment arms at the 24 month time point. Microfilarial clearance will be defined by non-detection of microfilaria in the night blood sample (NCT01213576)
Timeframe: 24 months

Interventionparticipants (Number)
Albendazole 400mg and Ivermectin 200mcg/kg Annually17
Albendazole 800mg and Ivermectin 400mcg/kg Annually17
Albendazole 400mg and Ivermectin 200mcg/kg Biannually14
Albendazole 800mg and Ivermectin 400mcg /kg Bi-annually17

Trials

14 trials available for albendazole and Filariasis

ArticleYear
Randomised controlled clinical trial of increased dose and frequency of albendazole and ivermectin on Wuchereria bancrofti microfilarial clearance in northern Malawi.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2015, Volume: 109, Issue:6

    Topics: Adult; Albendazole; Animals; Drug Therapy, Combination; Endemic Diseases; Female; Filariasis; Follow

2015
Enhanced efficacy of sequential administration of Albendazole for the clearance of Wuchereria bancrofti infection: Double blind RCT.
    Tropical biomedicine, 2015, Volume: 32, Issue:2

    Topics: Adult; Albendazole; Animals; Diethylcarbamazine; Double-Blind Method; Doxycycline; Drug Therapy, Com

2015
Reduction in levels of plasma vascular endothelial growth factor-A and improvement in hydrocele patients by targeting endosymbiotic Wolbachia sp. in Wuchereria bancrofti with doxycycline.
    The American journal of tropical medicine and hygiene, 2009, Volume: 80, Issue:6

    Topics: Adolescent; Adult; Albendazole; Animals; Anti-Bacterial Agents; Double-Blind Method; Doxycycline; Fi

2009
The kinetics of microfilaraemia and antigenaemia status among asymptomatic bancroftian filariasis before and after treatment.
    Journal of the Egyptian Society of Parasitology, 2009, Volume: 39, Issue:1

    Topics: Albendazole; Antigens, Helminth; Drug Therapy, Combination; Egypt; Filariasis; Filaricides; Humans;

2009
Use of high-dose, twice-yearly albendazole and ivermectin to suppress Wuchereria bancrofti microfilarial levels.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Dec-01, Volume: 51, Issue:11

    Topics: Adolescent; Adult; Aged; Albendazole; Animals; Drug Therapy, Combination; Endemic Diseases; Female;

2010
The effect of single dose ivermectin alone or in combination with albendazole on Wuchereria bancrofti infection in primary school children in Tanzania.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2004, Volume: 98, Issue:8

    Topics: Adolescent; Albendazole; Analysis of Variance; Animals; Child; Double-Blind Method; Drug Therapy, Co

2004
Effects of combined diethylcarbamazine and albendazole treatment of bancroftian filariasis on parasite uptake and development in Culex pipiens L.
    The American journal of tropical medicine and hygiene, 2005, Volume: 73, Issue:1

    Topics: Adult; Albendazole; Animals; Anthelmintics; Carrier State; Culex; Diethylcarbamazine; Drug Therapy,

2005
Tolerance and efficacy of combined diethylcarbamazine and albendazole for treatment of Wuchereria bancrofti and intestinal helminth infections in Haitian children.
    The American journal of tropical medicine and hygiene, 2005, Volume: 73, Issue:1

    Topics: Albendazole; Animals; Anthelmintics; Child; Diethylcarbamazine; Double-Blind Method; Drug Therapy, C

2005
A randomized, double-blind clinical trial of a 3-week course of doxycycline plus albendazole and ivermectin for the treatment of Wuchereria bancrofti infection.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Apr-15, Volume: 42, Issue:8

    Topics: Adolescent; Adult; Aged; Albendazole; Animals; Anthelmintics; Double-Blind Method; Doxycycline; Drug

2006
Efficacy of co-administered diethylcarbamazine and albendazole against adult Wuchereria bancrofti.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2006, Volume: 100, Issue:12

    Topics: Adolescent; Adult; Aged; Albendazole; Animals; Diethylcarbamazine; Drug Combinations; Filariasis; Fi

2006
Efficacy of a single-dose treatment with 300 mg diethylcarbamazine and a combination of 400 mg albendazole in reduction of Wuchereria bancrofti antigenemia and concomitant geohelminths in Myanmar migrants in Southern Thailand.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2006, Volume: 89, Issue:8

    Topics: Adult; Albendazole; Analysis of Variance; Animals; Antigens, Helminth; Diethylcarbamazine; Filariasi

2006
Efficacy of single-dose diethylcarbamazine compared with diethylcarbamazine combined with albendazole against Wuchereria bancrofti infection in Papua New Guinea.
    The American journal of tropical medicine and hygiene, 2007, Volume: 76, Issue:1

    Topics: Adult; Albendazole; Animals; Diethylcarbamazine; Female; Filariasis; Humans; Male; Wuchereria bancro

2007
Randomised placebo-controlled comparison of ivermectin and albendazole alone and in combination for Wuchereria bancrofti microfilaraemia in Haitian children.
    Lancet (London, England), 1997, Aug-16, Volume: 350, Issue:9076

    Topics: Albendazole; Animals; Child; Child, Preschool; Drug Therapy, Combination; Female; Filariasis; Filari

1997
Randomised placebo-controlled comparison of ivermectin and albendazole alone and in combination for Wuchereria bancrofti microfilaraemia in Haitian children.
    Lancet (London, England), 1997, Aug-16, Volume: 350, Issue:9076

    Topics: Albendazole; Animals; Child; Child, Preschool; Drug Therapy, Combination; Female; Filariasis; Filari

1997
Randomised placebo-controlled comparison of ivermectin and albendazole alone and in combination for Wuchereria bancrofti microfilaraemia in Haitian children.
    Lancet (London, England), 1997, Aug-16, Volume: 350, Issue:9076

    Topics: Albendazole; Animals; Child; Child, Preschool; Drug Therapy, Combination; Female; Filariasis; Filari

1997
Randomised placebo-controlled comparison of ivermectin and albendazole alone and in combination for Wuchereria bancrofti microfilaraemia in Haitian children.
    Lancet (London, England), 1997, Aug-16, Volume: 350, Issue:9076

    Topics: Albendazole; Animals; Child; Child, Preschool; Drug Therapy, Combination; Female; Filariasis; Filari

1997
Two-year follow-up of the microfilaraemia of asymptomatic brugian filariasis, after treatment with two, annual, single doses of ivermectin, diethylcarbamazine and albendazole, in various combinations.
    Annals of tropical medicine and parasitology, 2000, Volume: 94, Issue:6

    Topics: Adolescent; Adult; Aged; Albendazole; Animals; Brugia malayi; Diethylcarbamazine; Drug Administratio

2000

Other Studies

38 other studies available for albendazole and Filariasis

ArticleYear
Parasitic chyluria in a 72-year-old Sierra Leonean woman: A case report.
    African journal of primary health care & family medicine, 2019, Oct-15, Volume: 11, Issue:1

    Topics: Aged; Albendazole; Anthelmintics; Chyle; Female; Filariasis; Humans; Ivermectin; Kidney Diseases; Tr

2019
Filiarial chyluria with nephrotic-range proteinuria and associated hypoalbuminaemia and hypogammaglobulinaemia secondary to bilateral lymphorenal fistulae.
    BMJ case reports, 2017, Oct-04, Volume: 2017

    Topics: Agammaglobulinemia; Albendazole; Chyle; Combined Modality Therapy; Diagnosis, Differential; Filarias

2017
Albendazole and antibiotics synergize to deliver short-course anti-
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 11-07, Volume: 114, Issue:45

    Topics: Albendazole; Animals; Anti-Bacterial Agents; Benzimidazoles; Brugia malayi; Drug Synergism; Female;

2017
Validation of ultrasound bioimaging to predict worm burden and treatment efficacy in preclinical filariasis drug screening models.
    Scientific reports, 2018, 04-12, Volume: 8, Issue:1

    Topics: Albendazole; Animals; Brugia malayi; Drug Evaluation, Preclinical; Filariasis; Filaricides; Mice; Mi

2018
Novel Findings of Anti-Filarial Drug Target and Structure-Based Virtual Screening for Drug Discovery.
    International journal of molecular sciences, 2018, Nov-13, Volume: 19, Issue:11

    Topics: Albendazole; Amino Acid Sequence; Animals; Antinematodal Agents; Caenorhabditis elegans; Caenorhabdi

2018
Impact of six rounds of mass drug administration on Brugian filariasis and soil-transmitted helminth infections in eastern Indonesia.
    PLoS neglected tropical diseases, 2013, Volume: 7, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albendazole; Animals; Anthelmintics; Antibodies, Helmint

2013
Treatment of W. bancrofti (Wb) in HIV/Wb coinfections in South India.
    PLoS neglected tropical diseases, 2015, Volume: 9, Issue:3

    Topics: Adult; Albendazole; Animals; Case-Control Studies; CD4 Lymphocyte Count; Coinfection; Diethylcarbama

2015
Multiple frailty model for clustered interval-censored data with frailty selection.
    Statistical methods in medical research, 2017, Volume: 26, Issue:3

    Topics: Albendazole; Animals; Diethylcarbamazine; Filariasis; Humans; Likelihood Functions; Proportional Haz

2017
Maternal Infection Is a Risk Factor for Early Childhood Infection in Filariasis.
    PLoS neglected tropical diseases, 2015, Volume: 9, Issue:7

    Topics: Adult; Aging; Albendazole; Antigens, Helminth; Cohort Studies; Diethylcarbamazine; Female; Filariasi

2015
Impact of five annual rounds of mass drug administration with diethylcarbamazine and albendazole on Wuchereria bancrofti infection in American Samoa.
    The American journal of tropical medicine and hygiene, 2008, Volume: 78, Issue:6

    Topics: Adolescent; Adult; Albendazole; American Samoa; Animals; Anthelmintics; Antigens, Helminth; Child; C

2008
The impact of repeated rounds of mass drug administration with diethylcarbamazine plus albendazole on bancroftian filariasis in Papua New Guinea.
    PLoS neglected tropical diseases, 2008, Volume: 2, Issue:12

    Topics: Adult; Aging; Albendazole; Animals; Anopheles; Anthelmintics; Antigens, Helminth; Child; Culicidae;

2008
Mass drug administration against filariasis in India: perceptions and practices in a rural community in Kerala.
    Annals of tropical medicine and parasitology, 2009, Volume: 103, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albendazole; Analysis of Variance; Diethylcarbamazine; D

2009
Effects of albendazole on Litomosoides chagasfilhoi (Nematoda: Filarioidea) females in vivo.
    Parasitology research, 2010, Volume: 107, Issue:4

    Topics: Administration, Oral; Albendazole; Animals; Anthelmintics; Blood; Cytoplasm; Disease Models, Animal;

2010
Higher-dose, more frequent treatment of Wuchereria bancrofti.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Dec-01, Volume: 51, Issue:11

    Topics: Albendazole; Animals; Drug Therapy, Combination; Filariasis; Filaricides; Humans; Ivermectin; Parasi

2010
[A woman with painful, swollen legs].
    Nederlands tijdschrift voor geneeskunde, 2011, Volume: 155

    Topics: Aged; Albendazole; Female; Filariasis; Filaricides; Humans; Leg; Treatment Outcome

2011
Effects of 5 rounds of mass drug administration with diethylcarbamazine and albendazole on filaria-specific IgG4 titers in urine: 6-year follow-up study in Sri Lanka.
    Parasitology international, 2011, Volume: 60, Issue:4

    Topics: Adolescent; Albendazole; Animals; Antigens, Helminth; Child; Child, Preschool; Diethylcarbamazine; D

2011
A cell-based screen reveals that the albendazole metabolite, albendazole sulfone, targets Wolbachia.
    PLoS pathogens, 2012, Volume: 8, Issue:9

    Topics: Albendazole; Animals; Brugia malayi; Cell Line; Drosophila melanogaster; Filariasis; Microbial Sensi

2012
The influence of the mass administration of diethylcarbamazine, alone or with albendazole, on the prevalence of filarial antigenaemia.
    Annals of tropical medicine and parasitology, 2002, Volume: 96, Issue:6

    Topics: Adolescent; Adult; Albendazole; Animals; Antigens, Helminth; Child; Child, Preschool; Cross-Sectiona

2002
Bancroftian filariasis: clinical parasitologic and serologic evaluation after 4 years applying two antifilarial regimens.
    Journal of the Egyptian Society of Parasitology, 2002, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Albendazole; Animals; Antigens, Helminth; Child; Child, Preschool; Diethylcarbama

2002
Impact of mass chemotherapy for the control of filariasis on geohelminth infections in Sri Lanka.
    Annals of tropical medicine and parasitology, 2003, Volume: 97, Issue:4

    Topics: Albendazole; Animals; Anthelmintics; Ascariasis; Ascaris lumbricoides; Child; Diethylcarbamazine; Dr

2003
Detection of codon for amino acid 200 in isotype 1 beta-tubulin gene of Wuchereria bancrofti isolates, implicated in resistance to benzimidazoles in other nematodes.
    Acta tropica, 2003, Volume: 88, Issue:1

    Topics: Albendazole; Amino Acid Sequence; Animals; Anthelmintics; Base Sequence; Drug Resistance; Filariasis

2003
Clinical characteristics of post-treatment reactions to ivermectin/albendazole for Wuchereria bancrofti in a region co-endemic for Mansonella perstans.
    The American journal of tropical medicine and hygiene, 2003, Volume: 69, Issue:3

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Albendazole; Animals; Drug Adminis

2003
The in vitro effect of albendazole, ivermectin, diethylcarbamazine, and their combinations against infective third-stage larvae of nocturnally subperiodic Brugia malayi (Narathiwat strain): scanning electron microscopy.
    Journal of vector ecology : journal of the Society for Vector Ecology, 2004, Volume: 29, Issue:1

    Topics: Albendazole; Animals; Anthelmintics; Antinematodal Agents; Brugia malayi; Circadian Rhythm; Diethylc

2004
India expands mass chemotherapy to eradicate filariasis.
    The Lancet. Infectious diseases, 2004, Volume: 4, Issue:8

    Topics: Albendazole; Animals; Diethylcarbamazine; Drug Therapy, Combination; Filariasis; Filaricides; Filari

2004
Responses of Mastomys coucha, that have been infected with Brugia malayi and treated with diethylcarbamazine or albendazole, to re-exposure to infection.
    Annals of tropical medicine and parasitology, 2004, Volume: 98, Issue:8

    Topics: Albendazole; Animals; Brugia malayi; Cell Division; Diethylcarbamazine; Filariasis; Filaricides; Imm

2004
Filariasis elimination in Egypt: impact of low microfilaraemics as sources of infection for mosquitoes.
    Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 2003, Volume: 9, Issue:4

    Topics: Adolescent; Adult; Albendazole; Animals; Carrier State; Culex; Diethylcarbamazine; Disease Reservoir

2003
Detection of benzimidazole resistance-associated mutations in the filarial nematode Wuchereria bancrofti and evidence for selection by albendazole and ivermectin combination treatment.
    The American journal of tropical medicine and hygiene, 2005, Volume: 73, Issue:2

    Topics: Albendazole; Animals; Benzimidazoles; Burkina Faso; Drug Resistance; Drug Therapy, Combination; Fila

2005
Effect of yearly mass drug administration with diethylcarbamazine and albendazole on bancroftian filariasis in Egypt: a comprehensive assessment.
    Lancet (London, England), 2006, Mar-25, Volume: 367, Issue:9515

    Topics: Albendazole; Animals; Child; Child, Preschool; Cross-Sectional Studies; Culex; Diethylcarbamazine; E

2006
Population genetics of concurrent selection with albendazole and ivermectin or diethylcarbamazine on the possible spread of albendazole resistance in Wuchereria bancrofti.
    Parasitology, 2006, Volume: 133, Issue:Pt 5

    Topics: Albendazole; Alleles; Animals; Anthelmintics; Antiparasitic Agents; Culicidae; Diethylcarbamazine; D

2006
Anti-filarial activity of novel formulations of albendazole against experimental brugian filariasis.
    Parasitology, 2007, Volume: 134, Issue:Pt 4

    Topics: Albendazole; Animals; Brugia malayi; Dosage Forms; Filariasis; Filaricides; Gerbillinae; Murinae; Ti

2007
An analysis of the population genetics of potential multi-drug resistance in Wuchereria bancrofti due to combination chemotherapy.
    Parasitology, 2007, Volume: 134, Issue:Pt 7

    Topics: Age Factors; Albendazole; Animals; Antiparasitic Agents; Computer Simulation; Drug Resistance, Multi

2007
Comparative analysis of a chemotherapy effect on the cuticular surface of Wuchereria bancrofti adult worms in vivo.
    Parasitology research, 2007, Volume: 101, Issue:5

    Topics: Adult; Albendazole; Animals; Diethylcarbamazine; Drug Therapy, Combination; Filariasis; Filaricides;

2007
The anthelmintic effects of albendazole on Brugia pahangi.
    Journal of helminthology, 1980, Volume: 54, Issue:3

    Topics: Albendazole; Animals; Anthelmintics; Benzimidazoles; Brugia; Cats; Female; Filariasis; Filarioidea;

1980
The treatment of Filaroides osleri infestation with albendazole.
    Journal of the South African Veterinary Association, 1980, Volume: 51, Issue:4

    Topics: Albendazole; Animals; Anthelmintics; Benzimidazoles; Cat Diseases; Cats; Dogs; Filariasis; Male

1980
Macrofilaricidal activity of albendazole-ivermectin combination: histopathological evaluation of adult Molinema dessetae.
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1994, Volume: 45, Issue:3

    Topics: Albendazole; Animals; Drug Therapy, Combination; Filariasis; Filaricides; Filarioidea; Ivermectin; M

1994
Activity of albendazole-ivermectin combination and other filaricidal drugs against infective larvae, preadult, microfilariae and adult worms of Molinema dessetae in the rodent Proechimys oris.
    Parasite (Paris, France), 1994, Volume: 1, Issue:1

    Topics: Administration, Oral; Albendazole; Animals; Diethylcarbamazine; Drug Combinations; Female; Filariasi

1994
Another tropical-drug donation.
    Lancet (London, England), 1998, Feb-07, Volume: 351, Issue:9100

    Topics: Albendazole; Animals; Anthelmintics; Drug Industry; Filariasis; Humans; Wuchereria bancrofti

1998
The Global Lymphatic Filariasis Initiative.
    Tropical doctor, 2000, Volume: 30, Issue:3

    Topics: Albendazole; Anthelmintics; Filariasis; Humans; International Cooperation

2000