Page last updated: 2024-10-22

albendazole and Colorectal Cancer

albendazole has been researched along with Colorectal Cancer in 6 studies

Research Excerpts

ExcerptRelevanceReference
" dosing (ABZ, 150 mg/kg) led to the highest degree of tumor growth suppression (P<0."5.33Antitumor activity of albendazole against the human colorectal cancer cell line HT-29: in vitro and in a xenograft model of peritoneal carcinomatosis. ( Akhter, J; Lu, Y; Morris, DL; Pourgholami, MH; Wang, L, 2005)
"Our preclinical studies have shown that the widely used antiparasitic drug albendazole has potent antiproliferative activity against colorectal cancer (CRC) and hepatocellular carcinoma (HCC)."5.09Pilot study of albendazole in patients with advanced malignancy. Effect on serum tumor markers/high incidence of neutropenia. ( Jourdan, JL; Morris, DL; Pourgholami, MH, 2001)
"The interactions between ABZ and microtubule-binding agents, paclitaxel, vinblastine, colchicine, and 2-methoxyestradiol were characterized using median effect analysis method in HCT-116 colorectal cancer cells and DU145 prostate cancer cell line."3.79Combination of albendazole and 2-methoxyestradiol significantly improves the survival of HCT-116 tumor-bearing nude mice. ( Ehteda, A; Galettis, P; Morris, DL; Pillai, K, 2013)
"Albendazole (ABZ) is a microtubule depolymerizing agent with a remarkable activity against a variety of tumor cells in vitro and in vivo."1.38Complexation of albendazole with hydroxypropyl-β-cyclodextrin significantly improves its pharmacokinetic profile, cell cytotoxicity and antitumor efficacy in nude mice. ( Chu, SW; Ehteda, A; Galettis, P; Morris, DL; Pillai, K, 2012)
" dosing (ABZ, 150 mg/kg) led to the highest degree of tumor growth suppression (P<0."1.33Antitumor activity of albendazole against the human colorectal cancer cell line HT-29: in vitro and in a xenograft model of peritoneal carcinomatosis. ( Akhter, J; Lu, Y; Morris, DL; Pourgholami, MH; Wang, L, 2005)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ehteda, A2
Galettis, P2
Pillai, K2
Morris, DL4
Taranejoo, S1
Janmaleki, M1
Pachenari, M1
Seyedpour, SM1
Chandrasekaran, R1
Cheng, W1
Hourigan, K1
Park, S1
Kim, YS1
Kim, YJ1
Kyung, SY1
Park, JW1
Jeong, SH1
Lee, SP1
Chu, SW1
Pourgholami, MH2
Akhter, J1
Wang, L1
Lu, Y1
Jourdan, JL1

Trials

1 trial available for albendazole and Colorectal Cancer

ArticleYear
Pilot study of albendazole in patients with advanced malignancy. Effect on serum tumor markers/high incidence of neutropenia.
    Oncology, 2001, Volume: 61, Issue:1

    Topics: Adult; Aged; Albendazole; Antineoplastic Agents; Biomarkers, Tumor; Blood Cell Count; Carcinoembryon

2001

Other Studies

5 other studies available for albendazole and Colorectal Cancer

ArticleYear
Combination of albendazole and 2-methoxyestradiol significantly improves the survival of HCT-116 tumor-bearing nude mice.
    BMC cancer, 2013, Feb-23, Volume: 13

    Topics: 2-Methoxyestradiol; Albendazole; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherap

2013
Dual effect of F-actin targeted carrier combined with antimitotic drug on aggressive colorectal cancer cytoskeleton: Allying dissimilar cell cytoskeleton disrupting mechanisms.
    International journal of pharmaceutics, 2016, Nov-20, Volume: 513, Issue:1-2

    Topics: Actins; Albendazole; Antimitotic Agents; Cell Line, Tumor; Cell Survival; Chitosan; Colorectal Neopl

2016
Toxocariasis masquerading as liver and lung metastatic nodules in patents with gastrointestinal cancer: clinicopathologic study of five cases.
    Digestive diseases and sciences, 2012, Volume: 57, Issue:1

    Topics: Albendazole; Animals; Anthelmintics; Antibodies, Helminth; Biopsy; Colorectal Neoplasms; Diagnosis,

2012
Complexation of albendazole with hydroxypropyl-β-cyclodextrin significantly improves its pharmacokinetic profile, cell cytotoxicity and antitumor efficacy in nude mice.
    Anticancer research, 2012, Volume: 32, Issue:9

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Acetic Acid; Albendazole; Animals; beta-Cyclodextrins; Chromatogr

2012
Antitumor activity of albendazole against the human colorectal cancer cell line HT-29: in vitro and in a xenograft model of peritoneal carcinomatosis.
    Cancer chemotherapy and pharmacology, 2005, Volume: 55, Issue:5

    Topics: Albendazole; Animals; Anthelmintics; Apoptosis; Carcinoma; Colorectal Neoplasms; Humans; In Situ Nic

2005