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alanyl-glutamyl-aspartyl-glycine and Aging

alanyl-glutamyl-aspartyl-glycine has been researched along with Aging in 58 studies

*Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. [MeSH]

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.72)18.7374
1990's6 (10.34)18.2507
2000's39 (67.24)29.6817
2010's11 (18.97)24.3611
2020's1 (1.72)2.80

Authors

AuthorsStudies
Merkur'eva, GA; Ryzhak, GA1
Kvetnoĭ, IM; Lin'kova, NS; Poliakova, VO; Sevost'ianova, NN; Trofimov, AV1
Butenko, GM; Labunets, IF; Rodnichenko, AE1
Antonyk-Sheglova, IA; Khavinson, VKh; Korkushko, OV; Shatilo, VB1
Arutjunyan, A; Arutyunov, V; Korenevsky, A; Kozina, L; Milyutina, Y; Stepanov, M1
Khavinson, VKh1
Khavinson, VKh; Morozov, VG1
Azarskova, MV; Butenko, GM; Dragunova, VA; Khavinson, VKh; Labunets, IF; Magdich, LV; Pishel', IN1
Goncharova, ND; Khavinson, VKh; Shmaliĭ, AV; Vengerin, AA1
Azarskova, MV; Butenko, GM; Dragunova, VA; Khavinson, VKh; Kopylova, GV; Labunets, IF; Magdich, LV; Maksiuk, TV; Mikhal'skiĭ, SA; Rodnichenko, AE1
Labunets, IF1
Antoniuk-Shcheglova, IA; Goncharova, ND; Khavinson, VKh; Korkushko, OV; Lapin, BA; Magdich, LV; Shatilo, VB; Vengerin, AA1
Labunets', IF2
Arutiunian, AV; Chalisova, NI; Kozina, LS; Lesniak, VV; Miliutina, IuP; Morozova, PIu1
Blinova, TS; Gadzhieva, TS1
Anisimov, VN; Khavinson, VKh; Morozov, VG1
Anisimov, VN; Khavinson, VKh; Myl'nikov, SV; Oparina, TI1
Khavinson, VK; Myl'nikov, SV1
Anisimov, VN; Arutjunyan, AV; Khavinson, VK1
Anisimov, VN; Bondarenko, LA; Khavinson, VKh1
Anisimov, VN; Bondarenko, LA1
Anisimov, VN; Khavinson, VKh2
Anisimov, VN; Reiter, RJ1
Guo, JN; Guo, XP; Li, HX; Liu, SL; Meng, TG; Schatten, H; Song, CY; Sun, QY; Wang, ZB; Yue, X; Zhang, XR1
Baranchugova, LM; Kuznik, BI; Obydenko, VI; Pateyk, AV; Rusaeva, NS1
De Beer, JO; Deconinck, E; Moens, G; Van Hoeck, E; Vanhee, C1
Khavinson, VKh; Kuznik, BI; Lin'kova, NS; Tarnovskaia, SI1
Chalisova, NI; Khavinson, VKh; Lin'kova, NS; Orlova, AO; Ryzhak, GA; Zhekalov, AN1
Anisimov, VN; Ilyukha, VA; Khavinson, VKh; Khizhkin, EA; Morozov, AV; Svechkina, EB; Vinogradova, IA1
Anisimov, VN; Bukalev, AV; Khavinson, VKh; Semenchenko, AV; Vinogradova, IA; Zabezhinski, MA1
Baranchugova, LM; Kuznik, BI; Pateiuk, AV; Rusaeva, NS1
Anisimov, VN; Il'ina, TN; Iliukha, VA; Khavinson, VKh; Khizhkin, EA; Vinogradova, IA1
Golubeva, AG; Iliukha, VA; Niuppieva, MG; Uzenbaeva, LB; Vinogradova, IA1
Vinogradova, IA1
Baranchugova, LM; Kuznik, BI; Obydenko, VI; Pateiuk, AV; Rusaeva, NS1
Khavinson, VKh; Kuznik, BI; Lin'kova, NS1
Chaban, TV; Grigor'yan, RA; Khavinson, VKh; Oleinik, TL; Razumovskaya, AM; Razumovskii, MI; Trofimova, SV1
Anisimov, VN; Khavinson, VKh; Mikheev, VS; Popovich, IG; Rosenfeld, SV; Togo, EF1
Alimova, IN; Anisimov, VN; Francheski, K; Khavinsov, VKh; Manchini, R; Provintsiali, M1
Alimova, IN; Anisimov, VN; Khavinson, VKh; Semchenko, AV; Yashin, AI1
Gordova, LA; Khavinson, VKh; Malinin, VV; Nikitina, AA; Timofeeva, NM1
Anisimov, VN; Djeridane, Y; Khavinson, VKh; Touitou, Y1
Alimova, IN; Anisimov, VN; Khavinson, VKh; Popovich, IG; Rosenfeld, SV; Semenchenko, AV; Yashin, AI; Zabezhinski, MA; Zavarzina, NY1
Bablishvili, NK; Dvalishvili, NA; Jokhadze, TA; Khavinson, VKh; Lezhava, TA; Monaselidze, JR; Trofimova, SV1
Khavinson, VKh; Kuznik, BI; Malinin, VV; Pateiuk, AV1
Goncharova, ND; Khavinson, VKh; Lapin, BA; Vengerin, AA1
Anisimov, VN; Iashin, AI; Khavinson, VKh; Popovich, IG; Rozenfel'd, SV; Semenchenko, AV; Zabezhinskiĭ, MA1
Buadze, T; Dvalishvili, N; Kadotani, T; Lezhava, T; Monaselidze, J1
Svechkina, EB; Tiutiunnik, NN; Vinogradova, IA1
Rendakov, NL; Tiutiunnik, NN; Vinogradova, IA1
Fedorova, AS; Iliukha, VA; Iunash, VD; Khizhkin, EA; Unzhakov, AR; Vingradova, IA1
Anisimov, VN; Arutiunian, AV; Khavinson, VKh; Oparina, TI; Popovich, IG; Prokopenko, VM; Shtylik, AV; Zabezhinskiĭ, MA; Zavarzina, NIu; Zimina, OA1
Goncharova, N; Khavinson, V; Lapin, B1
Goncharova, ND; Khavinson, BK; Lapin, BA1
Arutyunyan, AV; Khavinson, VK; Myl'nikov, SV; Oparina, TI1
Golubev, AG; Khavinson, VKh1

Reviews

9 review(s) available for alanyl-glutamyl-aspartyl-glycine and Aging

ArticleYear
[Characteristics of the pineal gland and thymus relationship in aging].
    Advances in gerontology = Uspekhi gerontologii, 2011, Volume: 24, Issue:1

    Topics: Aging; Animals; Dipeptides; Humans; Neuroimmunomodulation; Oligopeptides; Peptides; Pineal Gland; Thymus Gland; Thymus Hormones

2011
Peptides and Ageing.
    Neuro endocrinology letters, 2002, Volume: 23 Suppl 3

    Topics: Aging; Animals; Humans; Oligopeptides; Peptide Hormones; Peptides; Pineal Gland

2002
[Geroprotective effect of thymalin and epithalamin].
    Advances in gerontology = Uspekhi gerontologii, 2002, Volume: 10

    Topics: Aged; Aging; Animals; Geriatrics; Humans; Peptides; Thymus Hormones

2002
Twenty years of study on effects of pineal peptide preparation: epithalamin in experimental gerontology and oncology.
    Annals of the New York Academy of Sciences, 1994, May-31, Volume: 719

    Topics: Aging; Animals; Endocrine Glands; Hormones; Immune System; Longevity; Mice; Neoplasms, Experimental; Nervous System; Peptides; Pineal Gland; Rats; Reproduction

1994
Effects of pineal peptide preparation Epithalamin on free-radical processes in humans and animals.
    Neuro endocrinology letters, 2001, Volume: 22, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Animals; Antioxidants; Catalase; Drosophila melanogaster; Free Radicals; Humans; Lipid Peroxidation; Melatonin; Middle Aged; Oxidation-Reduction; Peptides; Pineal Gland; Proteins; Rats; Reactive Oxygen Species; Superoxide Dismutase

2001
[Function of the pineal body in cancer and aging].
    Voprosy onkologii, 1990, Volume: 36, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Child; Child, Preschool; Female; Humans; Infant; Male; Melatonin; Mice; Middle Aged; Neoplasms; Peptides; Pineal Gland; Rats

1990
[Peptides and CCL11 and HMGB1 as molecular markers of aging: literature review and own data].
    Advances in gerontology = Uspekhi gerontologii, 2014, Volume: 27, Issue:3

    Topics: Aging; Animals; Atherosclerosis; Base Sequence; Binding Sites; Biomarkers; Chemokine CCL11; Dipeptides; Gene Expression Regulation; HMGB1 Protein; Humans; Molecular Sequence Data; Neurodegenerative Diseases; Oligopeptides

2014
[The use of peptide bioregulators for cancer prevention: results of 35 years of research experience and perspectives].
    Voprosy onkologii, 2009, Volume: 55, Issue:3

    Topics: Aging; Animals; Antineoplastic Agents; Delta Sleep-Inducing Peptide; Dipeptides; Humans; Mice; Neoplasms; Neuropeptides; Neurotransmitter Agents; Oligopeptides; Rats

2009
[Peptide Ala-Glu-Asp-Gly and interferon gamma: their role in immune response during aging].
    Advances in gerontology = Uspekhi gerontologii, 2012, Volume: 25, Issue:3

    Topics: Aging; Animals; Humans; Immunity, Innate; Interferon-gamma; Lymphocytes; Oligopeptides

2012

Trials

2 trial(s) available for alanyl-glutamyl-aspartyl-glycine and Aging

ArticleYear
[Effect of the pineal gland peptide preparation on the diurnal profile of arterial pressure in middle-aged and elderly women with ischemic heart disease and arterial hypertension].
    Advances in gerontology = Uspekhi gerontologii, 2008, Volume: 21, Issue:1

    Topics: Aged; Aging; Angina Pectoris; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Lipid Metabolism; Lipids; Melatonin; Middle Aged; Peptides; Pineal Gland; Treatment Outcome

2008
Peptide geroprotector from the pituitary gland inhibits rapid aging of elderly people: results of 15-year follow-up.
    Bulletin of experimental biology and medicine, 2011, Volume: 151, Issue:3

    Topics: Aged; Aging; Blood Glucose; Carbohydrate Metabolism; Cardiovascular Diseases; Cardiovascular System; Cholesterol; Circadian Rhythm; Exercise; Female; Follow-Up Studies; Humans; Lipid Metabolism; Male; Melatonin; Middle Aged; Peptides; Physical Endurance; Pineal Gland; Pituitary Gland

2011

Other Studies

47 other study(ies) available for alanyl-glutamyl-aspartyl-glycine and Aging

ArticleYear
[Influence of the pineal gland's factors on the cell composition of the bone marrow in animals of different age in conditions of changed thymus functional state].
    Advances in gerontology = Uspekhi gerontologii, 2011, Volume: 24, Issue:1

    Topics: Aging; Animals; Bone Marrow Cells; CD4-Positive T-Lymphocytes; Fibroblasts; Granulocyte-Macrophage Progenitor Cells; Male; Melatonin; Mice; Mice, Inbred CBA; Peptides; Pineal Gland; Seasons; Thymus Gland

2011
Melatonin and pineal gland peptides are able to correct the impairment of reproductive cycles in rats.
    Current aging science, 2012, Volume: 5, Issue:3

    Topics: 1,2-Dimethylhydrazine; Age Factors; Aging; Aging, Premature; Animals; Circadian Rhythm; Dopamine; Estrous Cycle; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Melatonin; Norepinephrine; Oligopeptides; Peptides; Pineal Gland; Rats; Rats, Wistar; Reproduction; Time Factors

2012
[Regulating effect of pineal gland peptides on development of T-lymphocytes in CBA aging mice: role of microenvironment of immune system organs and neuroendocrine factors].
    Advances in gerontology = Uspekhi gerontologii, 2003, Volume: 12

    Topics: Aging; Animals; Biogenic Monoamines; Bone Marrow; Cell Differentiation; Cell Division; Cell Movement; Immune System; Injections, Subcutaneous; Male; Melatonin; Mice; Mice, Inbred CBA; Neurosecretory Systems; Oligopeptides; Peptides; Pineal Gland; Spleen; T-Lymphocytes; Thymus Gland

2003
[Peptide correction of age-related pineal disturbances in monkeys].
    Advances in gerontology = Uspekhi gerontologii, 2003, Volume: 12

    Topics: Aging; Animals; Circadian Rhythm; Female; Injections, Intramuscular; Macaca mulatta; Melatonin; Oligopeptides; Peptides; Pineal Gland

2003
[The pineal gland's peptides factors and the rhythms of functions of the thymus and bone marrow in animals during aging].
    Advances in gerontology = Uspekhi gerontologii, 2004, Volume: 13

    Topics: Aging; Animals; Bone Marrow; Bone Marrow Cells; CD4-Positive T-Lymphocytes; Circadian Rhythm; Corticosterone; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Macrophages; Male; Mice; Mice, Inbred CBA; Peptides; Pineal Gland; Rats; Rats, Wistar; Seasons; Stromal Cells; Suprachiasmatic Nucleus; Testosterone; Thymic Factor, Circulating; Thymus Gland

2004
Antigen-induced changes in the endocrine function of the thymus in CBA mice during aging: role of peptide factors released by the pineal gland.
    Bulletin of experimental biology and medicine, 2005, Volume: 139, Issue:6

    Topics: Aging; Animals; Antigens; Erythrocytes; Female; Immunization; Injections, Intraperitoneal; Injections, Subcutaneous; Mice; Mice, Inbred CBA; Oligopeptides; Peptides; Pineal Gland; Sheep; T-Lymphocytes; Thymic Factor, Circulating; Thymus Gland; Thymus Hormones; Time Factors

2005
[Normalizing effect of the pineal gland peptides on the daily melatonin rhythm in old monkeys and elderly people].
    Advances in gerontology = Uspekhi gerontologii, 2007, Volume: 20, Issue:1

    Topics: Adult; Aged; Aging; Animals; Circadian Rhythm; Female; Humans; Macaca mulatta; Male; Melatonin; Middle Aged; Oligopeptides; Peptides; Pineal Gland

2007
[Circannual rhythms of bone marrow cell composition in animals during aging: the role of pineal factors].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2007, Volume: 53, Issue:6

    Topics: Aging; Animals; Biological Clocks; Bone Marrow Cells; Melatonin; Mice; Mice, Inbred CBA; Oligopeptides; Peptides; Pineal Gland; Seasons

2007
[The effect of pineal peptide preparations on proliferative activity in organotypic culture of the preoptic hypothalamus area].
    Advances in gerontology = Uspekhi gerontologii, 2007, Volume: 20, Issue:4

    Topics: Aging; Animals; Apoptosis; Cell Proliferation; Female; Immunohistochemistry; Oligopeptides; Peptides; Pineal Gland; Preoptic Area; Rats; Rats, Wistar; Tissue Culture Techniques; Tumor Suppressor Protein p53

2007
[Effect of epithalamin on hypophyseal and ovarian gonadotropic function].
    Akusherstvo i ginekologiia, 1980, Issue:9

    Topics: Aging; Animals; Cattle; Estrus; Female; Gonadotropins, Pituitary; Ovary; Peptides; Photic Stimulation; Pineal Gland; Pituitary Gland; Pregnancy; Rats

1980
[Effect of melatonin and epithalamin on life span and lipid peroxidation in Drosophila melanogaster].
    Doklady Akademii nauk, 1997, Volume: 352, Issue:5

    Topics: Aging; Animals; Drosophila melanogaster; Life Expectancy; Lipid Peroxidation; Melatonin; Peptides

1997
Effect of pineal tetrapeptide on antioxidant defense in Drosophila melanogaster.
    Bulletin of experimental biology and medicine, 2000, Volume: 129, Issue:4

    Topics: Aging; Animals; Antioxidants; Catalase; Drosophila melanogaster; Free Radicals; Peptides; Pineal Gland

2000
[Age-related effects in thymocytes differentiation: role of pineal gland peptide factors].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2002, Volume: 48, Issue:1

    Topics: Aging; Animals; Cell Differentiation; Hormones; Male; Mice; Mice, Inbred CBA; Peptides; Pineal Gland; T-Lymphocyte Subsets; Thymic Factor, Circulating; Thymus Gland

2002
Effect of pineal peptide preparation (epithalamin) on life span and pineal and serum melatonin level in old rats.
    Annals of the New York Academy of Sciences, 1992, Dec-26, Volume: 673

    Topics: Aging; Animals; Estrus; Female; Longevity; Male; Melatonin; Neoplasms; Peptides; Pineal Gland; Rats; Serotonin

1992
[Age-related characteristics of the effects of epithalamin on serotonin metabolism in the pineal gland of rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1992, Volume: 113, Issue:2

    Topics: Aging; Animals; Male; Melatonin; Peptides; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin

1992
[Effect of an epiphyseal polypeptide preparation on life expectancy and frequency of spontaneous tumors in aged female rats].
    Doklady Akademii nauk SSSR, 1991, Volume: 319, Issue:1

    Topics: Aging; Animals; Epiphyses; Female; Life Expectancy; Neoplasms, Experimental; Peptides; Rats

1991
Epitalon protects against post-ovulatory aging-related damage of mouse oocytes
    Aging, 2022, 04-12, Volume: 14, Issue:7

    Topics: Aging; Animals; Female; Mice; Oligopeptides; Oocytes; Ovulation; Reactive Oxygen Species

2022
Effect of peptides Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly on the morphology of the thymus in hypophysectomized young and old birds.
    Bulletin of experimental biology and medicine, 2013, Volume: 154, Issue:5

    Topics: Aging; Animals; Chickens; Hypophysectomy; Oligopeptides; Thymus Gland

2013
Identification of the small research tetra peptide Epitalon, assumed to be a potential treatment for cancer, old age and Retinitis Pigmentosa in two illegal pharmaceutical preparations.
    Drug testing and analysis, 2015, Volume: 7, Issue:3

    Topics: Aging; Antineoplastic Agents; Chromatography, Liquid; Humans; Illicit Drugs; Mass Spectrometry; Neoplasms; Oligopeptides; Retinitis Pigmentosa

2015
[Short peptides stimulate skin cell regeneration during ageing].
    Advances in gerontology = Uspekhi gerontologii, 2014, Volume: 27, Issue:4

    Topics: Aging; Animals; Carnosine; Cell Proliferation; Fibroblasts; In Vitro Techniques; Male; Oligopeptides; Rats, Wistar; Regeneration; Skin; Skin Aging

2014
Effects of Geroprotectors on Age-Related Changes in Proteolytic Digestive Enzyme Activities at Different Lighting Conditions.
    Bulletin of experimental biology and medicine, 2015, Volume: 159, Issue:6

    Topics: Age Factors; Aging; Animals; Animals, Outbred Strains; Circadian Rhythm; Digestion; Enzyme Activation; Female; Light; Lighting; Male; Melatonin; Oligopeptides; Peptide Hydrolases; Photic Stimulation; Photoperiod; Rats

2015
Geroprotective effect of ala-glu-asp-gly peptide in male rats exposed to different illumination regimens.
    Bulletin of experimental biology and medicine, 2008, Volume: 145, Issue:4

    Topics: Aging; Animals; Animals, Inbred Strains; Light; Lighting; Longevity; Male; Neoplasms; Oligopeptides; Photoperiod; Phototherapy; Radiation Dosage; Rats

2008
[Effects of epithalon and cortagene on immunity and hemostasis in neonatally hypophysectomized chicken and old birds].
    Advances in gerontology = Uspekhi gerontologii, 2008, Volume: 21, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Antibody Formation; Blood Coagulation; Chickens; Erythrocytes; Fibrinolysis; Hemostasis; Hypophysectomy; Immunity, Cellular; Oligopeptides; Pituitary Gland

2008
[The influences of geroprotectors on age-related changes of antioxidant system in rats liver under different light condition].
    Advances in gerontology = Uspekhi gerontologii, 2008, Volume: 21, Issue:3

    Topics: Aging; Animals; Antioxidants; Female; Liver; Male; Melatonin; Oligopeptides; Photoperiod; Rats; Seasons; Tocopherols

2008
[The influence of melatonin and epithalon on blood leukocyte count and leukocyte alkaline phosphatase in rats under different lighting conditions during ontogenesis].
    Advances in gerontology = Uspekhi gerontologii, 2008, Volume: 21, Issue:3

    Topics: Aging; Alkaline Phosphatase; Animals; Female; Leukocyte Count; Leukocytes; Male; Melatonin; Oligopeptides; Photoperiod; Rats

2008
[Effect of preparations melatonin and epitalon on the age-related dynamics of thyrotrophic activity of the hypophysis and thyroid gland function in different light regimes].
    Advances in gerontology = Uspekhi gerontologii, 2009, Volume: 22, Issue:4

    Topics: Aging; Animals; Circadian Rhythm; Female; Light; Male; Melatonin; Oligopeptides; Pituitary Gland; Rats; Seasons; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

2009
[Effects of Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly peptides on hormonal activity and thyroid morphology in hypophysectomized mature and old birds].
    Advances in gerontology = Uspekhi gerontologii, 2011, Volume: 24, Issue:1

    Topics: Aging; Animals; Chickens; Hypophysectomy; Oligopeptides; Organ Size; Pituitary Gland; Thyroid Gland; Thyroid Hormones

2011
Effect of epithalon on age-specific changes in the retina in rats with hereditary pigmentary dystrophy.
    Bulletin of experimental biology and medicine, 2002, Volume: 133, Issue:1

    Topics: Aging; Animals; Oligopeptides; Rats; Retina; Retinitis Pigmentosa

2002
Effect of epithalon on the incidence of chromosome aberrations in senescence-accelerated mice.
    Bulletin of experimental biology and medicine, 2002, Volume: 133, Issue:3

    Topics: Aging; Animals; Bone Marrow Cells; Chromosome Aberrations; Female; Melatonin; Mice; Oligopeptides

2002
Epithalon inhibits tumor growth and expression of HER-2/neu oncogene in breast tumors in transgenic mice characterized by accelerated aging.
    Bulletin of experimental biology and medicine, 2002, Volume: 133, Issue:2

    Topics: Adenocarcinoma; Aging; Animals; Antineoplastic Agents; Dipeptides; Female; Gene Expression; Genes, erbB-2; Mammary Neoplasms, Animal; Mice; Mice, Transgenic; Oligopeptides; Random Allocation; RNA, Messenger

2002
Epithalon decelerates aging and suppresses development of breast adenocarcinomas in transgenic her-2/neu mice.
    Bulletin of experimental biology and medicine, 2002, Volume: 134, Issue:2

    Topics: Adenocarcinoma; Aging; Animals; Breast Neoplasms; Mice; Mice, Transgenic; Oligopeptides; Receptor, ErbB-2

2002
Effect of vilon and epithalon on activity of enzymes in epithelial and subepithelial layers in small intestine of old rats.
    Bulletin of experimental biology and medicine, 2002, Volume: 134, Issue:6

    Topics: Administration, Oral; Aging; Animals; Dipeptides; Epithelium; Intestinal Mucosa; Intestine, Small; Male; Oligopeptides; Rats; Rats, Wistar; Time Factors

2002
Effect of a synthetic pineal tetrapeptide (Ala-Glu-Asp-GLy) on melatonin secretion by the pineal gland of young and old rats.
    Journal of endocrinological investigation, 2003, Volume: 26, Issue:3

    Topics: Adrenergic beta-Agonists; Aging; Animals; In Vitro Techniques; Isoproterenol; Male; Melatonin; Oligopeptides; Osmolar Concentration; Pineal Gland; Rats; Rats, Wistar

2003
Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice.
    Biogerontology, 2003, Volume: 4, Issue:4

    Topics: Aging; Animals; Biomarkers; Body Temperature; Body Weight; Bone Marrow Cells; Chromosome Aberrations; Estrus; Feeding Behavior; Female; Life Expectancy; Mice; Neoplasms, Experimental; Oligopeptides

2003
Peptide Epitalon activates chromatin at the old age.
    Neuro endocrinology letters, 2003, Volume: 24, Issue:5

    Topics: Aged; Aging; Cells, Cultured; Euchromatin; Heterochromatin; Hot Temperature; Humans; Lymphocytes; Oligopeptides; Protein Denaturation; Ribosomal Proteins; Transcriptional Activation

2003
[Effect of epitalon on the immunity and hemostasis in hypophysectomized chicken and old hens].
    Advances in gerontology = Uspekhi gerontologii, 2004, Volume: 13

    Topics: Aging; Animals; Blood Cell Count; Chickens; Fibrinolysis; Hemoglobins; Hemostasis; Hypophysectomy; Immunity; Lymphoid Tissue; Oligopeptides; Pituitary Gland

2004
Peptide correction of age-related hormonal dysfunction of the pancreas in monkeys.
    Bulletin of experimental biology and medicine, 2004, Volume: 138, Issue:1

    Topics: Aging; Animals; Blood Glucose; Female; Glucose Tolerance Test; Insulin; Islets of Langerhans; Macaca mulatta; Oligopeptides; Pancreas; Peptides; Time Factors

2004
[Effect of epitalon and melatonin on life span and spontaneous carcinogenesis in senescence accelerated mice (SAM)].
    Voprosy onkologii, 2005, Volume: 51, Issue:1

    Topics: Aging; Animals; Cell Transformation, Neoplastic; Female; Life Expectancy; Melatonin; Mice; Oligopeptides

2005
Anti-aging peptide bioregulators induce reactivation of chromatin.
    Georgian medical news, 2006, Issue:133

    Topics: Aging; Biodegradation, Environmental; Chromatin; Dipeptides; Humans; Oligopeptides

2006
[Influence of light regimens, melatonin, and epitalon on amylase activity in the pancreas and small intestine in rats of different age].
    Advances in gerontology = Uspekhi gerontologii, 2006, Volume: 19

    Topics: Aging; Amylases; Animals; Female; Intestine, Small; Light; Male; Melatonin; Oligopeptides; Pancreas; Rats; Rats, Inbred Strains

2006
[Effect of age, different light conditions, melatonin, and epitalon on lysosomal proteinase activity in the liver and kidneys of rats].
    Advances in gerontology = Uspekhi gerontologii, 2006, Volume: 19

    Topics: Aging; Animals; Female; Kidney; Light; Liver; Lysosomes; Male; Melatonin; Oligopeptides; Peptide Hydrolases; Rats; Rats, Inbred Strains

2006
[Age-related changes of exercise capacity and some biochemical indices of rat muscles under influence of different light conditions and pineal preparations].
    Advances in gerontology = Uspekhi gerontologii, 2007, Volume: 20, Issue:1

    Topics: Aging; Animals; Antioxidants; Circadian Rhythm; Light; Melatonin; Muscle, Skeletal; Oligopeptides; Physical Fitness; Pineal Gland; Rats; Rats, Inbred Strains

2007
[Effect of pineal peptide on parameters of the biological age and life span in mice].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2001, Volume: 87, Issue:1

    Topics: Aging; Animals; Body Temperature; Body Weight; Eating; Estrus; Female; Free Radicals; Longevity; Mice; Mice, Inbred CBA; Motor Activity; Muscle Fatigue; Neoplasms; Oligopeptides; Reproduction

2001
Synthetic tetrapeptide epitalon restores disturbed neuroendocrine regulation in senescent monkeys.
    Neuro endocrinology letters, 2001, Volume: 22, Issue:4

    Topics: Aging; Animals; Circadian Rhythm; Endocrine System Diseases; Female; Macaca mulatta; Melatonin; Nervous System Diseases; Oligopeptides; Osmolar Concentration

2001
Regulatory effect of Epithalon on production of melatonin and cortisol in old monkeys.
    Bulletin of experimental biology and medicine, 2001, Volume: 131, Issue:4

    Topics: Aging; Animals; Antioxidants; Female; Hydrocortisone; Macaca mulatta; Melatonin; Oligopeptides

2001
Effects of peptides on generation of reactive oxygen species in subcellular fractions of Drosophila melanogaster.
    Bulletin of experimental biology and medicine, 2001, Volume: 132, Issue:1

    Topics: Aging; Animals; Antioxidants; Cell Fractionation; Dipeptides; Drosophila melanogaster; Female; Larva; Male; Oligopeptides; Reactive Oxygen Species

2001
[Aging of the pineal gland].
    Advances in gerontology = Uspekhi gerontologii, 2002, Volume: 9

    Topics: Aging; Animals; Antioxidants; Female; Melatonin; Monoamine Oxidase Inhibitors; Oligopeptides; Pineal Gland; S-Adenosylmethionine

2002