Page last updated: 2024-08-25

alantolactone and Disease Models, Animal

alantolactone has been researched along with Disease Models, Animal in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Dou, W; Han, M; Luo, X; Ren, G; Ren, Y; Sun, A; Wang, Z; Yu, Z; Yue, B; Zhang, J1
Cheng, W; Feng, L; Hou, Q; Huo, X; Lan, Y; Ma, X; Sun, C; Sun, D; Tian, X; Wang, C; Wang, X; Wang, Y; Xing, J; Yu, Z; Zhang, B1
Huang, L; Mi, J; Tong, J; Wu, Y; Xu, X; Yan, H; Zhang, C; Zhang, Z1
Alonso Blasi, N; Benezra, C; Fraginals, R; Lepoittevin, JP1

Other Studies

5 other study(ies) available for alantolactone and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Activation of PXR by alantolactone ameliorates DSS-induced experimental colitis via suppressing NF-κB signaling pathway.
    Scientific reports, 2019, 11-12, Volume: 9, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Colitis; Dextran Sulfate; Disease Models, Animal; Fluorescent Antibody Technique; Gene Knockdown Techniques; Humans; Lactones; Male; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; NF-kappa B; Pregnane X Receptor; Sesquiterpenes, Eudesmane; Signal Transduction

2019
Alantolactone, a natural sesquiterpene lactone, has potent antitumor activity against glioblastoma by targeting IKKβ kinase activity and interrupting NF-κB/COX-2-mediated signaling cascades.
    Journal of experimental & clinical cancer research : CR, 2017, 07-12, Volume: 36, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Apoptosis; Binding Sites; Biomarkers; Blood-Brain Barrier; Caspases; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclooxygenase 2; Cytochromes c; Disease Models, Animal; Dose-Response Relationship, Drug; E1A-Associated p300 Protein; Humans; I-kappa B Kinase; Lactones; Male; Mice; Models, Biological; Molecular Conformation; NF-kappa B; Promoter Regions, Genetic; Protein Binding; Rats; Sesquiterpenes, Eudesmane; Signal Transduction

2017
Targeting non-oncogene ROS pathway by alantolactone in B cell acute lymphoblastic leukemia cells.
    Life sciences, 2019, Jun-15, Volume: 227

    Topics: Animals; Apoptosis; B-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Humans; Lactones; Male; Mice; Mice, Inbred NOD; Mice, SCID; Mitochondria; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Cell Culture; Reactive Oxygen Species; Sesquiterpenes, Eudesmane

2019
A murine in vitro model of allergic contact dermatitis to sesquiterpene alpha-methylene-gamma-butyrolactones.
    Archives of dermatological research, 1992, Volume: 284, Issue:5

    Topics: Animals; Cross Reactions; Dermatitis, Allergic Contact; Disease Models, Animal; In Vitro Techniques; Lactones; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Sesquiterpenes; Sesquiterpenes, Eudesmane; Species Specificity

1992