alanine has been researched along with Thyroid Neoplasms in 8 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Thyroid Neoplasms: Tumors or cancer of the THYROID GLAND.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lysine was the second amino acid that differentiated these two groups of PTC patients." | 1.91 | Alterations in the amino acid profile in patients with papillary thyroid carcinoma with and without Hashimoto's thyroiditis. ( Hellmann, A; Korczynska, J; Mika, A; Taciak, A; Turyn, J; Zwara, A, 2023) |
| "Most cases of multiple endocrine neoplasia type 2B (MEN-2B) are attributable to a germline methionine to threonine mutation at codon 918 (M918T) of the RET proto-oncogene; very few cases of a germline alanine to phenylalanine mutation at codon 883 (A883F) are reported without a clear description of the clinical course." | 1.37 | Multiple endocrine neoplasia type 2B with a RET proto-oncogene A883F mutation displays a more indolent form of medullary thyroid carcinoma compared with a RET M918T mutation. ( Cote, G; Grubbs, EG; Habra, MA; Hu, MI; Jasim, S; Jimenez, C; Rich, TA; Waguespack, SG; Ying, AK, 2011) |
| "S891A mutation caused medullary thyroid cancer (MTC) in 69." | 1.36 | The clinical spectrum of multiple endocrine neoplasia type 2a caused by the rare intracellular RET mutation S891A. ( Aylwin, S; Beck-Peccoz, P; Diaz-Cano, S; Dralle, H; Fugazzola, L; Izatt, L; Machens, A; McGregor, A; Schulte, KM; Talat, N, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Hellmann, A | 1 |
| Turyn, J | 1 |
| Zwara, A | 1 |
| Korczynska, J | 1 |
| Taciak, A | 1 |
| Mika, A | 1 |
| Ngan, ES | 1 |
| Lang, BH | 1 |
| Liu, T | 1 |
| Shum, CK | 1 |
| So, MT | 1 |
| Lau, DK | 1 |
| Leon, TY | 1 |
| Cherny, SS | 1 |
| Tsai, SY | 1 |
| Lo, CY | 1 |
| Khoo, US | 1 |
| Tam, PK | 1 |
| Garcia-Barceló, MM | 1 |
| Schulte, KM | 1 |
| Machens, A | 1 |
| Fugazzola, L | 1 |
| McGregor, A | 1 |
| Diaz-Cano, S | 1 |
| Izatt, L | 1 |
| Aylwin, S | 1 |
| Talat, N | 1 |
| Beck-Peccoz, P | 1 |
| Dralle, H | 1 |
| Jasim, S | 1 |
| Ying, AK | 1 |
| Waguespack, SG | 1 |
| Rich, TA | 1 |
| Grubbs, EG | 1 |
| Jimenez, C | 1 |
| Hu, MI | 1 |
| Cote, G | 1 |
| Habra, MA | 1 |
| Rumiantseva, UV | 1 |
| Il'in, AA | 1 |
| Rumiantseva, PO | 1 |
| Medvedev, VS | 1 |
| Abrosimov, AIu | 1 |
| Zaletaev, DV | 1 |
| Kjaer, S | 1 |
| Kurokawa, K | 1 |
| Perrinjaquet, M | 1 |
| Abrescia, C | 1 |
| Ibáñez, CF | 1 |
| Paschke, R | 1 |
| Tonacchera, M | 1 |
| Van Sande, J | 1 |
| Parma, J | 1 |
| Vassart, G | 1 |
| Mahlstedt, J | 1 |
| Joseph, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Personalized Cancer Therapy for Patients With Metastatic Medullary Thyroid or Metastatic Colon Cancer[NCT02363647] | 10 participants (Actual) | Interventional | 2015-01-31 | Terminated (stopped due to No Current Funding) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for alanine and Thyroid Neoplasms
| Article | Year |
|---|---|
[Decompensation of autonomous thyroid adenoma after long-term iodine intake (author's transl)].
Topics: Adenoma; Adult; Alanine; Contrast Media; Female; Humans; Iodobenzoates; Long-Term Care; Middle Aged; | 1973 |
7 other studies available for alanine and Thyroid Neoplasms
| Article | Year |
|---|---|
Alterations in the amino acid profile in patients with papillary thyroid carcinoma with and without Hashimoto's thyroiditis.
Topics: Alanine; Amino Acids; Antibodies; Arginine; Glutamic Acid; Glycine; Hashimoto Disease; Humans; Lysin | 2023 |
A germline mutation (A339V) in thyroid transcription factor-1 (TITF-1/NKX2.1) in patients with multinodular goiter and papillary thyroid carcinoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Animals; Carcinoma, Papillary; Case-Control Stu | 2009 |
The clinical spectrum of multiple endocrine neoplasia type 2a caused by the rare intracellular RET mutation S891A.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Alanine; Amino Acid Substitutio | 2010 |
Multiple endocrine neoplasia type 2B with a RET proto-oncogene A883F mutation displays a more indolent form of medullary thyroid carcinoma compared with a RET M918T mutation.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Alanine; Carcinoma, Neuroendocrine; Female; Germ-Line | 2011 |
[Familial well-differentiated thyroid carcinoma].
Topics: Adenocarcinoma, Follicular; Adult; Aged; Alanine; Carcinoma, Medullary; Carcinoma, Papillary; Female | 2006 |
Self-association of the transmembrane domain of RET underlies oncogenic activation by MEN2A mutations.
Topics: Alanine; Amino Acid Sequence; Animals; Cell Membrane; Cysteine; Dimerization; Disulfides; Drosophila | 2006 |
Identification and functional characterization of two new somatic mutations causing constitutive activation of the thyrotropin receptor in hyperfunctioning autonomous adenomas of the thyroid.
Topics: Adenoma; Alanine; Amino Acid Sequence; Base Sequence; Cell Line; Codon; Cyclic AMP; Gene Expression; | 1994 |