alanine has been researched along with Thalassemias in 16 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The biosynthesis of two types of human fetal hemoglobin (Hb F), namely Hb F with G gamma chains having glycine in position 136 and Hb F with A gamma chains having alanine in position 136, was studied in blood samples and in cultures of erythroid precursors from blood of patients with different hemoglobinopathies." | 3.66 | The synthesis of fetal hemoglobin types in red blood cells and in BFU-E derived colonies from peripheral blood of patients with sickle cell anemia, beta+ - and delta beta-thalassemia, various forms of hereditary persistence of fetal hemoglobin, normal adu ( Efremov, GD; Gravely, ME; Harris, HF; Howard, JS; Huisman, TH; Reese, AL; Wilson, JB, 1979) |
| " In Greek double heterozygotes for beta-thalassemia and the hereditary persistence of fetal hemoglobin, fetal hemoglobin is increased above the level of hemoglobin F in simple heterozygotes and gamma-chains with glycine in position 136 become apparent." | 3.65 | Nature of fetal hemoglobin in the Greek type of hereditary persistence of fetal hemoglobin with and without concurrent beta-thalassemia. ( Apell, G; Bouver, N; Huisman, TH; Schroeder, WA; Shelton, JB; Shelton, JR; Stamatoyannopoulos, G, 1970) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saglio, G | 1 |
| Camaschella, C | 1 |
| Guerrasio, A | 1 |
| Cambrin, GR | 1 |
| Capaldi, A | 1 |
| Pich, PG | 1 |
| Trento, M | 1 |
| Mazza, U | 1 |
| Honig, GR | 1 |
| Shamsuddin, M | 1 |
| Zaizov, R | 1 |
| Steinherz, M | 1 |
| Solar, I | 1 |
| Kirschmann, C | 1 |
| Clegg, JB | 3 |
| Metaxatou-Mavromati, A | 2 |
| Kattamis, C | 2 |
| Sofroniadou, K | 1 |
| Wood, WG | 3 |
| Weatherall, DJ | 3 |
| Amin, AB | 1 |
| Pandya, NL | 1 |
| Diwin, PP | 1 |
| Darbre, PD | 1 |
| White, JM | 1 |
| Lie-Injo, LE | 1 |
| Randhawa, ZI | 1 |
| Kane, JP | 1 |
| Ganesan, J | 1 |
| George, R | 1 |
| Alter, BP | 1 |
| Huisman, TH | 4 |
| Efremov, GD | 2 |
| Reese, AL | 1 |
| Howard, JS | 1 |
| Gravely, ME | 1 |
| Harris, HF | 1 |
| Wilson, JB | 2 |
| Nicola, P | 1 |
| Musella, R | 1 |
| David, O | 1 |
| Zanolini, C | 1 |
| Miniero, R | 1 |
| Beutler, E | 1 |
| Lang, A | 1 |
| Lehmann, H | 1 |
| Lassman, MN | 1 |
| Genel, M | 1 |
| Wise, JK | 1 |
| Hendler, R | 1 |
| Felig, P | 1 |
| Schroeder, WA | 3 |
| Sukumaran, PK | 1 |
| Rahbar, S | 1 |
| Golban-Moghadam, N | 1 |
| Saoodi, H | 1 |
| Sadikario, A | 1 |
| Stojmirovic, E | 1 |
| Shelton, JR | 2 |
| Shelton, JB | 2 |
| Apell, G | 2 |
| Brodie, AR | 1 |
| Mann, JR | 1 |
| MacNeish, AS | 1 |
| Bannister, D | 1 |
| Modell, CB | 1 |
| Latter, A | 1 |
| Steadman, JH | 1 |
| Huehns, ER | 1 |
| Stamatoyannopoulos, G | 1 |
| Bouver, N | 1 |
16 other studies available for alanine and Thalassemias
| Article | Year |
|---|---|
G gamma and a gamma globin chain synthesis in bone marrow and peripheral blood of beta-thalassaemia homozygotes.
Topics: Adolescent; Adult; Alanine; Blood Cells; Bone Marrow; Cells, Cultured; Female; Globins; Glycine; Hom | 1982 |
Hemoglobin Petah Tikva (alpha 110 ala replaced by asp): a new unstable variant with alpha-thalassemia-like expression.
Topics: Alanine; Aspartic Acid; Chemical Phenomena; Chemistry; Child, Preschool; Genetic Variation; Genotype | 1981 |
Occurrence of G gamma Hb F in Greek HPFH: analysis of heterozygotes and compound heterozygotes with beta thalassaemia.
Topics: Adult; Alanine; Erythrocyte Indices; Female; Fetal Hemoglobin; Globins; Glycine; Greece; Hemoglobin | 1979 |
A comparison of the homozygous states for G gamma and G gamma A gamma delta beta thalassaemia.
Topics: Adolescent; Adult; Alanine; Child; Child, Preschool; Female; Fetal Hemoglobin; Glycine; Hemoglobins; | 1979 |
Heterogeneity of hemoglobin gamma chains in normal newborns and in cases of alpha and beta thalassemia.
Topics: Alanine; Cyanogen Bromide; Fetal Hemoglobin; Glycine; Homozygote; Humans; Infant, Newborn; Peptides; | 1979 |
The G gamma:A gamma composition of fetal hemoglobin in fetuses and newborns.
Topics: Alanine; Anemia, Sickle Cell; Electrophoresis, Polyacrylamide Gel; Female; Fetal Hemoglobin; Fetus; | 1979 |
The synthesis of fetal hemoglobin types in red blood cells and in BFU-E derived colonies from peripheral blood of patients with sickle cell anemia, beta+ - and delta beta-thalassemia, various forms of hereditary persistence of fetal hemoglobin, normal adu
Topics: Adult; Alanine; Anemia, Sickle Cell; Cells, Cultured; Chromatography, High Pressure Liquid; Clone Ce | 1979 |
[Erythrocyte activity of ALA-dehydrase in major beta-thalassemia].
Topics: Adolescent; Alanine; Child; Child, Preschool; Erythrocytes; Humans; Hydro-Lyases; Infant; Thalassemi | 1976 |
Hemoglobin Duarte: (alpha2beta2 62(E6)Ala leads to Pro): a new unstable hemoglobin with increased oxygen affinity.
Topics: Adult; Alanine; Amino Acid Sequence; Amino Acids; Anemia, Hemolytic; Cell Survival; Chromium Radiois | 1974 |
Carbohydrate homeostasis and pancreatic islet cell funtion in thalassemia.
Topics: Adult; Alanine; Blood Glucose; Carbohydrate Metabolism; Child; Child, Preschool; Female; Glucagon; G | 1974 |
A second type of hereditary persistence of foetal haemoglobin in India.
Topics: Adult; Alanine; Amino Acid Sequence; Child; Child, Preschool; Female; Fetal Hemoglobin; Globins; Gly | 1973 |
Hemoglobin Lepore Boston in two Iranian families.
Topics: Alanine; Amino Acids; Blood Protein Electrophoresis; Boston; Child; Chromatography, DEAE-Cellulose; | 1974 |
Chemical heterogeneity of foetal haemoglobin in the Lepore haemoglobinopathy.
Topics: Adolescent; Adult; Alanine; Amino Acid Sequence; Chemical Phenomena; Chemistry; Child; Chromatograph | 1974 |
Delta-beta-thalassaemia in a Chinese family.
Topics: Adult; Alanine; Asian People; Black People; Carbon Isotopes; Child; Child, Preschool; Chromatography | 1972 |
Haemoglobin synthesis in beta-thalassaemia.
Topics: Alanine; Blood Protein Electrophoresis; Chromatography; Chromatography, Gel; Hemoglobins; Humans; In | 1969 |
Nature of fetal hemoglobin in the Greek type of hereditary persistence of fetal hemoglobin with and without concurrent beta-thalassemia.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Chromatography, Paper; Fetal Hemoglobin; Glycine; Hem | 1970 |