Page last updated: 2024-11-08

alanine and Stomach Neoplasms

alanine has been researched along with Stomach Neoplasms in 45 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Stomach Neoplasms: Tumors or cancer of the STOMACH.

Research Excerpts

ExcerptRelevanceReference
"Using PCR based restriction fragment length polymorphism and single strand conformational polymorphism, we determined single nucleotide exchanges in the p16 and cyclin D1 genes among 56 esophageal adenocarcinomas (ADC) arising in Barrett's esophagus, 95 cardiac gastric ADC, and in 191 distal gastric ADC."7.73Polymorphism of p16 INK4A and cyclin D1 in adenocarcinomas of the upper gastrointestinal tract. ( Gabbert, HE; Geddert, H; Kiel, S; Sarbia, M; Willers, R; Zhang, J; Zotz, RB, 2005)
"In this prospective, randomized, multicenter, open-label, and comparative study, patients who had undergone ESD for EGC or gastric adenoma were randomized into groups receiving either rabeprazole monotherapy (10 mg/day, n=64) or a combination of rabeprazole plus rebamipide (300 mg/day, n=66)."5.22Limited Effect of Rebamipide in Addition to Proton Pump Inhibitor (PPI) in the Treatment of Post-Endoscopic Submucosal Dissection Gastric Ulcers: A Randomized Controlled Trial Comparing PPI Plus Rebamipide Combination Therapy with PPI Monotherapy. ( Akahoshi, K; Akiho, H; Aso, A; Harada, N; Iboshi, Y; Ihara, E; Iwasa, T; Nakamura, K; Nakamura, N; Ochiai, T; Ogino, H; Takayanagi, R, 2016)
"Using PCR based restriction fragment length polymorphism and single strand conformational polymorphism, we determined single nucleotide exchanges in the p16 and cyclin D1 genes among 56 esophageal adenocarcinomas (ADC) arising in Barrett's esophagus, 95 cardiac gastric ADC, and in 191 distal gastric ADC."3.73Polymorphism of p16 INK4A and cyclin D1 in adenocarcinomas of the upper gastrointestinal tract. ( Gabbert, HE; Geddert, H; Kiel, S; Sarbia, M; Willers, R; Zhang, J; Zotz, RB, 2005)
" No serious adverse events were observed in any of the patients in either group."2.80Efficacy and safety of 1-week Helicobacter pylori eradication therapy and 7-week rebamipide treatment after endoscopic submucosal dissection of early gastric cancer in comparison with 8-week PPI standard treatment: a randomized, controlled, prospective, m ( Azuma, T; Higuchi, K; Iguchi, M; Machida, H; Morita, Y; Naito, Y; Takeuchi, T; Takeuchi, Y; Tamada, T; Tominaga, K; Uedo, N; Yagi, N; Yamao, J; Yazumi, S, 2015)
"We examined 90 patients with early gastric cancer who had undergone ESD."2.78Efficacy of treatment with rebamipide for endoscopic submucosal dissection-induced ulcers. ( Asakuma, Y; Kashida, H; Kawasaki, M; Kudo, M; Matsui, S; Sakurai, T; Takayama, M, 2013)
" pylori, especially after MNU administration to promote carcinogenesis and the effects of the long-term administration of rebamipide or nimesulide were evaluated."2.42Chemoprevention of Helicobacter pylori-associated gastric carcinogenesis in a mouse model: is it possible? ( Cho, SW; Hahm, KB; Han, SU; Kim, DY; Kim, JH; Kim, MW; Kim, YB; Lee, JS; Nahm, KT; Oh, TY; Song, YJ; Surh, YJ; Yoo, BM, 2003)
"Improvement of gastritis is expressed not only in quantity but also in quality of gastritis, which is shown as the reduction of iNOS expression in the gastric mucosa."2.42Review article: clinical significance of mucosal-protective agents: acid, inflammation, carcinogenesis and rebamipide. ( Haruma, K; Ito, M, 2003)
"Globally, gastric cancer is the third most common cancer and the third leading cause of cancer death."1.72Microbiota and metabolites alterations in proximal and distal gastric cancer patients. ( Chen, X; Chen, Y; Dai, D; Huang, Y; Jin, W; Lin, W; Teng, L; Wang, H; Wang, W; Yang, Y; Zhang, H; Zhang, J; Zhang, Y, 2022)
"There were significant differences in gastric cancer incidence rates according to age, sex, and initial diagnosis at the time of index ESD."1.51Chemopreventive Effect of Rebamipide against Gastric Cancer in Patients who undergo Endoscopic Resection for Early Gastric Neoplasms: A Nationwide Claims Study. ( Lee, H; Seo, GH, 2019)
"MNNG-induced carcinogenesis and may also inhibit progression of cancer in rats."1.42Preventive effect of rebamipide on N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rats. ( Ebi, M; Hayashi, N; Joh, T; Katano, T; Kataoka, H; Mizoshita, T; Mori, Y; Ozeki, K; Shimura, T; Tanida, S; Tatematsu, M; Tsukamoto, H; Tsukamoto, T, 2015)
"Mass screening for gastric cancer (GC), particularly using endoscopy, may not be the most practical approach as a result of its high cost, lack of acceptance, and poor availability."1.40Noninvasive diagnosis and evaluation of curative surgery for gastric cancer by using NMR-based metabolomic profiling. ( Bang, EJ; Cho, SI; Hwang, GS; Jang, YJ; Jung, J; Jung, Y; Kwak, JM; Park, S; Ryu, DH, 2014)
"pylori obtained from gastric cancer patients secreted Tip alpha in significantly higher amounts than did H."1.35TNF-alpha-inducing protein, a carcinogenic factor secreted from H. pylori, enters gastric cancer cells. ( Fujiki, H; Hayashi, T; Imai, K; Kuzuhara, T; Matsumoto, H; Nishizono, A; Ogawa, T; Ono, Y; Suganuma, M; Yamaguchi, K, 2008)
"Its effect on gastric cancer cell growth and its regulatory mechanisms remain unknown."1.34Rebamipide inhibits gastric cancer cell growth. ( Arakawa, T; Pai, R; Tanigawa, T; Tarnawski, AS, 2007)
"We examined in human gastric cancer AGS cells: (1) survivin expression, (2) localization of survivin and Aurora-B, (3) cell proliferation, and (4) effects of specific survivin siRNA and/or rebamipide (free radical scavenging drug) on survivin and Aurora-B expression and cell proliferation."1.33Rebamipide inhibits gastric cancer growth by targeting survivin and Aurora-B. ( Chai, J; Chiou, SK; Chu, EC; Pai, R; Tarnawski, A, 2005)
"In specimens (Borrmann type III) with tubular adenocarcinoma, resonance peaks were observed at 1."1.32Ex vivo proton MR spectroscopy (1H-MRS) for evaluation of human gastric carcinoma. ( Cha, SS; Cho, JY; Choi, KS; Eun, CK; Kim, J; Lee, J; Lee, SY; Mun, CW; Nam, SH; Shin, WJ; Yang, YI, 2004)
"We have recently reported that a gastric cancer cell line, MKN45, produced a massive amount of IL-8 upon coculture with live H."1.30Molecular analysis of suppression of interleukin-8 production by rebamipide in Helicobacter pylori-stimulated gastric cancer cell lines. ( Aihara, M; Azuma, A; Funakoshi, Y; Imagawa, K; Kikuchi, M; Matsushima, K; Mukaida, N; Ohmoto, Y; Shindo, Y; Takizawa, H; Tsuchimoto, D, 1998)
"In lung cancer tissue, the activity of aminopeptidase toward L-leucinamide was abnormally low, while the activity of arylamidase toward L-leucyl-beta-napthylamide was similar to that in normal lung."1.25Aminopeptidases and arylamidases in normal and cancer tissues in humans. ( Arima, T; Fujii, S; Niinobe, M; Okuda, H; Tamura, Y, 1975)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19906 (13.33)18.7374
1990's5 (11.11)18.2507
2000's11 (24.44)29.6817
2010's18 (40.00)24.3611
2020's5 (11.11)2.80

Authors

AuthorsStudies
Yuan, Q1
Deng, D1
Pan, C1
Ren, J1
Wei, T1
Wu, Z1
Zhang, B1
Li, S2
Yin, P1
Shang, D1
Yang, Y2
Dai, D1
Jin, W1
Huang, Y1
Zhang, Y1
Chen, Y1
Wang, W1
Lin, W1
Chen, X2
Zhang, J3
Wang, H1
Zhang, H1
Teng, L1
Liu, C1
Zheng, Q1
Zhao, L1
Kong, PF1
Yang, H1
Liu, X1
Jung, DH1
Park, JC1
Lee, YC2
Lee, SK1
Shin, SK1
Chung, H1
Park, JJ1
Kim, JH4
Youn, YH1
Park, H1
Lee, JS2
Jeon, SW1
Lee, HS1
Kwon, YH1
Nam, SY1
Bae, HI1
Seo, AN1
Videira, RA1
Andrade, PB1
Monteiro, LS1
Valentão, P1
Ferreira, PMT1
Pereira, DM1
Ichida, T1
Ueyama, S1
Eto, T1
Kusano, F1
Sakai, Y2
Seo, GH1
Lee, H1
Takayama, M1
Matsui, S1
Kawasaki, M1
Asakuma, Y1
Sakurai, T1
Kashida, H1
Kudo, M1
Jung, J1
Jung, Y1
Bang, EJ1
Cho, SI1
Jang, YJ1
Kwak, JM1
Ryu, DH1
Park, S1
Hwang, GS1
Higuchi, K1
Takeuchi, T1
Uedo, N1
Takeuchi, Y1
Naito, Y2
Yagi, N1
Tominaga, K1
Machida, H1
Tamada, T1
Morita, Y2
Yazumi, S1
Yamao, J1
Iguchi, M1
Azuma, T2
Xiong, J1
Lai, S1
Zhang, P1
Li, Q1
Wei, Y1
Wang, T1
Liu, L1
Ma, X1
Chen, D1
Tsukamoto, H1
Mizoshita, T1
Katano, T1
Hayashi, N1
Ozeki, K1
Ebi, M1
Shimura, T1
Mori, Y1
Tanida, S1
Kataoka, H1
Tsukamoto, T1
Tatematsu, M1
Joh, T1
Han, X1
Jiang, K1
Wang, B1
Zhou, L1
Sekiguchi, F1
Sekimoto, T1
Ogura, A1
Kawabata, A1
Kang, DW3
Noh, YN1
Hwang, WC2
Choi, KY2
Min, do S2
Nakamura, K1
Ihara, E1
Akiho, H1
Akahoshi, K1
Harada, N1
Ochiai, T1
Nakamura, N1
Ogino, H1
Iwasa, T1
Aso, A1
Iboshi, Y1
Takayanagi, R1
Calabrese, C1
Pisi, A1
Di Febo, G1
Liguori, G1
Filippini, G1
Cervellera, M1
Righi, V1
Lucchi, P1
Mucci, A1
Schenetti, L1
Tonini, V1
Tosi, MR1
Tugnoli, V1
Min, G1
Park, DY1
Hong, KW1
Fujiwara, S1
Toyonaga, T1
Kawakami, F1
Itoh, T1
Yoshida, M2
Kutsumi, H1
Kabeya, M1
Ina, K1
Yuasa, S1
Kikuchi, F1
Tajiri, C1
Kato, T1
Hibi, S1
Minagawa, Y1
Furuta, R1
Kayukawa, S1
Kataoka, T1
Kawai, M1
Kobayashi, M1
Takeuchi, M1
Hashimoto, S1
Mizuno, K1
Sato, Y1
Narisawa, R1
Aoyagi, Y1
Shin, WG1
Kim, SJ1
Choi, MH1
Kim, KO1
Jang, HJ1
Park, CH1
Baek, IH1
Kim, KH1
Baik, GH1
Kae, SH1
Kim, HY1
Park, MH1
Ko, GH1
Ha, WS1
Kim, KS1
Min, DS1
Hahm, KB2
Song, YJ1
Oh, TY1
Surh, YJ1
Kim, YB1
Yoo, BM1
Han, SU1
Nahm, KT1
Kim, MW1
Kim, DY1
Cho, SW2
Yoshida, N1
Ishikawa, T1
Ichiishi, E1
Yoshida, Y1
Hanashiro, K1
Kuchide, M1
Uchiyama, K1
Kokura, S1
Ichikawa, H1
Yamamura, Y1
Okanoue, T1
Yoshikawa, T1
Haruma, K1
Ito, M1
DIETRICH, FS1
COPE, C1
RIVERS, S1
KRANTZ, S1
BAUM, G1
BECK, HJ1
RODENSKY, PL1
PIPER, DW1
MACOUN, ML1
BUILDER, JE1
FENTON, BH1
Shimada, S1
Inoue, K1
Kuramoto, M1
Suzuki, S1
Yamamoto, K1
Ogawa, M1
Mun, CW1
Cho, JY1
Shin, WJ1
Choi, KS1
Eun, CK1
Cha, SS1
Lee, J1
Yang, YI1
Nam, SH1
Kim, J1
Lee, SY1
Tarnawski, A1
Pai, R2
Chiou, SK1
Chai, J1
Chu, EC1
Geddert, H1
Kiel, S1
Zotz, RB1
Willers, R1
Gabbert, HE1
Sarbia, M1
Tanigawa, T1
Arakawa, T1
Tarnawski, AS1
Suganuma, M1
Yamaguchi, K1
Ono, Y1
Matsumoto, H1
Hayashi, T1
Ogawa, T1
Imai, K1
Kuzuhara, T1
Nishizono, A1
Fujiki, H1
Abasov, IT1
Sauerwein, HP1
Michels, RP1
Cejka, V1
Tatara, T1
Noguchi, J1
Fukushima, K1
Ishihara, Y1
Ohkochi, S1
Uedaira, H1
Yoshida, T1
Sato, R1
Mahmood, S1
Kawasaki, S1
Futai, M1
Maeda, M1
Lee, KJ1
Chung, MH1
Aihara, M1
Azuma, A1
Takizawa, H1
Tsuchimoto, D1
Funakoshi, Y1
Shindo, Y1
Ohmoto, Y1
Imagawa, K1
Kikuchi, M1
Mukaida, N1
Matsushima, K1
Masamune, A1
Shimosegawa, T1
Tamura, Y1
Niinobe, M1
Arima, T1
Okuda, H1
Fujii, S1
Izawa, M1
Takayama, S1
Shindo-Okada, N1
Doi, S1
Kimura, M1
Katsuki, M1
Nishimura, S1
Spellman, CM1
Fottrell, PF1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Plasma and Urine Metabolomics for Biomarker Discovery in Children With Eosinophilic Esophagitis[NCT03107819]24 participants (Actual)Observational2017-03-29Completed
Is Rebamipide Effective on the Healing of Iatrogenic Gastric Ulcer After Endoscopic Mucosal Resection? : Multicenter, Randomized, and Prospective Study[NCT01167101]290 participants (Actual)Interventional2009-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for alanine and Stomach Neoplasms

ArticleYear
Rebamipide plus proton pump inhibitor versus proton pump inhibitor alone in the treatment of endoscopic submucosal dissection-induced gastric ulcer: a meta-analysis of randomized controlled trials.
    Medicine, 2014, Volume: 93, Issue:12

    Topics: Adenoma; Aged; Aged, 80 and over; Alanine; Anti-Ulcer Agents; Drug Therapy, Combination; Endoscopy,

2014
Chemoprevention of Helicobacter pylori-associated gastric carcinogenesis in a mouse model: is it possible?
    Journal of biochemistry and molecular biology, 2003, Jan-31, Volume: 36, Issue:1

    Topics: Alanine; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cyto

2003
Review article: clinical significance of mucosal-protective agents: acid, inflammation, carcinogenesis and rebamipide.
    Alimentary pharmacology & therapeutics, 2003, Volume: 18 Suppl 1

    Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Anticarcinogenic Agents; Gastri

2003
Helicobacter pylori infection, oxidative DNA damage, gastric carcinogenesis, and reversibility by rebamipide.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:9 Suppl

    Topics: Alanine; Antioxidants; Apoptosis; DNA Damage; Helicobacter Infections; Helicobacter pylori; Humans;

1998

Trials

12 trials available for alanine and Stomach Neoplasms

ArticleYear
Comparison of the Efficacy of Polaprezinc Plus Proton Pump Inhibitor and Rebamipide Plus Proton Pump Inhibitor Treatments for Endoscopic Submucosal Dissection-induced Ulcers.
    Journal of clinical gastroenterology, 2021, 03-01, Volume: 55, Issue:3

    Topics: Alanine; Anti-Ulcer Agents; Carnosine; Drug Therapy, Combination; Endoscopic Mucosal Resection; Huma

2021
Rebamipide for the Improvement of Gastric Atrophy and Intestinal Metaplasia: A Prospective, Randomized, Pilot Study.
    Digestive diseases and sciences, 2022, Volume: 67, Issue:6

    Topics: Alanine; Atrophy; Gastric Mucosa; Gastritis, Atrophic; Helicobacter Infections; Helicobacter pylori;

2022
Randomized Controlled Trial Comparing the Effects of Vonoprazan Plus Rebamipide and Esomeprazole Plus Rebamipide on Gastric Ulcer Healing Induced by Endoscopic Submucosal Dissection.
    Internal medicine (Tokyo, Japan), 2019, Jan-15, Volume: 58, Issue:2

    Topics: Aged; Aged, 80 and over; Alanine; Anti-Ulcer Agents; Drug Therapy, Combination; Endoscopic Mucosal R

2019
Efficacy of treatment with rebamipide for endoscopic submucosal dissection-induced ulcers.
    World journal of gastroenterology, 2013, Sep-14, Volume: 19, Issue:34

    Topics: Adenocarcinoma; Aged; Alanine; Anti-Ulcer Agents; Dissection; Female; Gastroscopy; Humans; Iatrogeni

2013
Efficacy and safety of 1-week Helicobacter pylori eradication therapy and 7-week rebamipide treatment after endoscopic submucosal dissection of early gastric cancer in comparison with 8-week PPI standard treatment: a randomized, controlled, prospective, m
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2015, Volume: 18, Issue:3

    Topics: Aged; Alanine; Anti-Bacterial Agents; Clarithromycin; Dissection; Early Detection of Cancer; Female;

2015
Effect of Rebamipide on the Premalignant Progression of Chronic Gastritis: A Randomized Controlled Study.
    Clinical drug investigation, 2015, Volume: 35, Issue:10

    Topics: Alanine; CDX2 Transcription Factor; Disease Progression; Female; Gastric Mucosa; Gastritis; Helicoba

2015
Limited Effect of Rebamipide in Addition to Proton Pump Inhibitor (PPI) in the Treatment of Post-Endoscopic Submucosal Dissection Gastric Ulcers: A Randomized Controlled Trial Comparing PPI Plus Rebamipide Combination Therapy with PPI Monotherapy.
    Gut and liver, 2016, Nov-15, Volume: 10, Issue:6

    Topics: Adenoma; Aged; Alanine; Anti-Ulcer Agents; Drug Therapy, Combination; Endoscopic Mucosal Resection;

2016
A randomized controlled trial of rebamipide plus rabeprazole for the healing of artificial ulcers after endoscopic submucosal dissection.
    Journal of gastroenterology, 2011, Volume: 46, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Alanine; Anti-Ulcer Agents; Disease Progression; Drug

2011
[Pilot study on clinical effects of rebamipide gargle against oral mucositis induced by fluoropyrimidines].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:7

    Topics: Alanine; Antimetabolites, Antineoplastic; Colonic Neoplasms; Fluorouracil; Humans; Mouthwashes; Pilo

2011
Contributing factors to gastric ulcer healing after endoscopic submucosal dissection including the promoting effect of rebamipide.
    Digestive diseases and sciences, 2012, Volume: 57, Issue:1

    Topics: Aged; Aged, 80 and over; Alanine; Anti-Ulcer Agents; Drug Therapy, Combination; Endoscopy, Digestive

2012
Can rebamipide and proton pump inhibitor combination therapy promote the healing of endoscopic submucosal dissection-induced ulcers? A randomized, prospective, multicenter study.
    Gastrointestinal endoscopy, 2012, Volume: 75, Issue:4

    Topics: Adenoma; Aged; Alanine; Anti-Ulcer Agents; Carcinoma; Chi-Square Distribution; Confidence Intervals;

2012
Preoperative administration of rebamipide significantly lowers body temperature and circulating interleukin-6 in gastric cancer patients after gastrectomy.
    Digestive surgery, 2003, Volume: 20, Issue:6

    Topics: Aged; Alanine; Chemoprevention; Enzyme Inhibitors; Female; Fever; Gastrectomy; Humans; Interleukin-6

2003

Other Studies

29 other studies available for alanine and Stomach Neoplasms

ArticleYear
Integration of transcriptomics, proteomics, and metabolomics data to reveal HER2-associated metabolic heterogeneity in gastric cancer with response to immunotherapy and neoadjuvant chemotherapy.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Alanine; Aspartic Acid; Glutamates; Humans; Immunotherapy; Metabolomics; Neoadjuvant Therapy; Proteo

2022
Microbiota and metabolites alterations in proximal and distal gastric cancer patients.
    Journal of translational medicine, 2022, 09-30, Volume: 20, Issue:1

    Topics: Alanine; Arginine; Aspartic Acid; Feces; Glutamates; Hormones; Humans; Metabolomics; Microbiota; RNA

2022
Surface-Enhanced Raman Scattering Enantioselective Detection of Gastric Cancer-Related d-Amino Acids in Saliva Based on Enzyme-Mediated Cascade Reaction.
    Analytical chemistry, 2023, 09-05, Volume: 95, Issue:35

    Topics: Alanine; Amino Acids; Antifibrinolytic Agents; Humans; Hydrogen Peroxide; Proline; Saliva; Spectrum

2023
Toxicity and structure-activity relationship (SAR) of α,β-dehydroamino acids against human cancer cell lines.
    Toxicology in vitro : an international journal published in association with BIBRA, 2018, Volume: 47

    Topics: Alanine; Antineoplastic Agents; Apoptosis; Caspases; Cell Line; Cell Line, Tumor; Cell Shape; Drug D

2018
Chemopreventive Effect of Rebamipide against Gastric Cancer in Patients who undergo Endoscopic Resection for Early Gastric Neoplasms: A Nationwide Claims Study.
    Digestion, 2019, Volume: 100, Issue:4

    Topics: Administrative Claims, Healthcare; Aged; Alanine; Anti-Ulcer Agents; Dose-Response Relationship, Dru

2019
Noninvasive diagnosis and evaluation of curative surgery for gastric cancer by using NMR-based metabolomic profiling.
    Annals of surgical oncology, 2014, Volume: 21 Suppl 4

    Topics: Alanine; Area Under Curve; Arginine; Biomarkers, Tumor; CA-19-9 Antigen; Carcinoembryonic Antigen; C

2014
Preventive effect of rebamipide on N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2015, Volume: 67, Issue:3

    Topics: Adenocarcinoma; Alanine; Animals; Antioxidants; Carcinogenesis; Carcinogens; Disease Models, Animal;

2015
Endogenous Hydrogen Sulfide Enhances Cell Proliferation of Human Gastric Cancer AGS Cells.
    Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:5

    Topics: Alanine; Alkynes; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cystathionine gamm

2016
Rebamipide attenuates Helicobacter pylori CagA-induced self-renewal capacity via modulation of β-catenin signaling axis in gastric cancer-initiating cells.
    Biochemical pharmacology, 2016, 08-01, Volume: 113

    Topics: Alanine; Animals; Anticarcinogenic Agents; Antigens, Bacterial; Apoptosis; Bacterial Proteins; beta

2016
Biochemical alterations from normal mucosa to gastric cancer by ex vivo magnetic resonance spectroscopy.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:6

    Topics: Adenocarcinoma; Aged; Alanine; Biomarkers, Tumor; Choline; Endoscopy, Gastrointestinal; Female; Gast

2008
Rebamipide-induced downregulation of phospholipase D inhibits inflammation and proliferation in gastric cancer cells.
    Experimental & molecular medicine, 2010, Aug-31, Volume: 42, Issue:8

    Topics: Alanine; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplast

2010
Rebamipide abolishes Helicobacter pylori CagA-induced phospholipase D1 expression via inhibition of NFκB and suppresses invasion of gastric cancer cells.
    Oncogene, 2013, Jul-25, Volume: 32, Issue:30

    Topics: Alanine; Anti-Ulcer Agents; Antigens, Bacterial; Bacterial Proteins; Gene Expression Regulation, Enz

2013
The effect of rebamipide on Helicobacter pylori extract-mediated changes of gene expression in gastric epithelial cells.
    Alimentary pharmacology & therapeutics, 2003, Volume: 18 Suppl 1

    Topics: Alanine; Anti-Ulcer Agents; Chemokine CCL5; Chemokine CXCL2; Down-Regulation; Epithelial Cells; Fibr

2003
Clinical trial with alanine mustard.
    Cancer chemotherapy reports, 1962, Volume: 23

    Topics: Alanine; Lung Neoplasms; Lymphoma; Mustard Plant; Nitrogen Mustard Compounds; Stomach Neoplasms

1962
NONPROTEOLYTIC ENZYMES IN GASTRIC JUICE.
    The American journal of digestive diseases, 1963, Volume: 8

    Topics: Alanine; Alkaline Phosphatase; Anemia; Anemia, Pernicious; Aspartate Aminotransferases; Duodenal Ulc

1963
Ex vivo proton MR spectroscopy (1H-MRS) for evaluation of human gastric carcinoma.
    Magnetic resonance imaging, 2004, Volume: 22, Issue:6

    Topics: Adenocarcinoma; Alanine; Choline; Feasibility Studies; Humans; Lipid Metabolism; Magnetic Resonance

2004
Rebamipide inhibits gastric cancer growth by targeting survivin and Aurora-B.
    Biochemical and biophysical research communications, 2005, Aug-19, Volume: 334, Issue:1

    Topics: Alanine; Aurora Kinase B; Aurora Kinases; Cell Line, Tumor; Cell Proliferation; Dose-Response Relati

2005
Polymorphism of p16 INK4A and cyclin D1 in adenocarcinomas of the upper gastrointestinal tract.
    Journal of cancer research and clinical oncology, 2005, Volume: 131, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alanine; Barrett Esophagus; Cardia; Case-Control Stu

2005
Rebamipide inhibits gastric cancer cell growth.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:1

    Topics: Alanine; Anti-Ulcer Agents; Cell Proliferation; Cyclin-Dependent Kinases; Extracellular Signal-Regul

2007
TNF-alpha-inducing protein, a carcinogenic factor secreted from H. pylori, enters gastric cancer cells.
    International journal of cancer, 2008, Jul-01, Volume: 123, Issue:1

    Topics: Alanine; Animals; Bacterial Proteins; Biomarkers, Tumor; Blotting, Western; Carcinogens; Chronic Dis

2008
Chromatographic analysis of free amino acids of gastric juice in patients with cancer and other stomach diseases.
    Neoplasma, 1967, Volume: 14, Issue:4

    Topics: Adult; Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Cystine; Duodenal Ulcer; Femal

1967
Alanine turnover in the postabsorptive state and during parenteral hyperalimentation before and after surgery.
    Metabolism: clinical and experimental, 1981, Volume: 30, Issue:7

    Topics: Absorption; Adult; Alanine; Fasting; Female; Humans; Kinetics; Male; Middle Aged; Parenteral Nutriti

1981
Proton NMR spectroscopic studies of serum as an aid to perioperative cellular metabolic monitoring.
    Physiological chemistry and physics and medical NMR, 1995, Volume: 27, Issue:2

    Topics: Adult; Aged; Alanine; Blood Chemical Analysis; Blood Glucose; Esophageal Neoplasms; Fatty Acids, Non

1995
GATA-6 DNA binding protein expressed in human gastric adenocarcinoma MKN45 cells.
    FEBS letters, 1997, Sep-08, Volume: 414, Issue:2

    Topics: Adenocarcinoma; Alanine; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Conserved Seque

1997
Molecular analysis of suppression of interleukin-8 production by rebamipide in Helicobacter pylori-stimulated gastric cancer cell lines.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:9 Suppl

    Topics: Alanine; Anti-Ulcer Agents; Blotting, Northern; DNA Primers; Gene Expression Regulation, Neoplastic;

1998
Rebamipide inhibits ceramide-induced interleukin-8 production in Kato III human gastric cancer cells.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:2

    Topics: Alanine; Anti-Ulcer Agents; Blotting, Northern; Blotting, Western; Ceramides; Enzyme Activation; Enz

2001
Aminopeptidases and arylamidases in normal and cancer tissues in humans.
    Cancer research, 1975, Volume: 35, Issue:4

    Topics: Alanine; Amides; Aminopeptidases; Colon; Digestive System; Humans; Ileum; Kidney; Leucine; Liver; Li

1975
Inhibition of chemical carcinogenesis in vivo by azatyrosine.
    Cancer research, 1992, Mar-15, Volume: 52, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Alanine; Animals; Antibiotics, Antineoplastic; Drug Screening Assa

1992
Similarities between pyruvate kinase from human placenta and tumours.
    FEBS letters, 1973, Dec-01, Volume: 37, Issue:2

    Topics: Adenosine Triphosphate; Alanine; Carcinoma; Chromatography, Gel; Chromatography, Ion Exchange; Elect

1973