alanine has been researched along with Sjogren's Syndrome in 9 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Sjogren's Syndrome: Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " No difference in the incidence of adverse events was seen between the two groups, confirming the safety of rebamipide." | 2.74 | Efficacy and safety of rebamipide for the treatment of dry mouth symptoms in patients with Sjögren's syndrome: a double-blind placebo-controlled multicenter trial. ( Kawakami, A; Koni, I; Nishinarita, M; Nishiyama, S; Ohta, S; Oka, H; Sawada, S; Sugai, S; Sugiyama, E; Takahashi, H; Takei, M; Umehara, H; Yamaji, K, 2009) |
| "Rheumatic diseases were IA (60%) and CTD (40%)." | 1.56 | Clinical outcomes of hospitalised patients with COVID-19 and chronic inflammatory and autoimmune rheumatic diseases: a multicentric matched cohort study. ( Alvaro-Gracia, JM; Blanco, R; Carmona, L; Castrejón, I; Fernández Fernández, D; Fernandez-Nebro, A; Galindo, M; Gonzalez-Gay, MA; Lledó, A; Manrique-Arija, S; Martinez-Lopez, D; Mena Vázquez, N; Mera-Varela, A; Pablos, JL; Retuerto, M, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Jin-Sil, P | 1 |
| Sun-Hee, H | 1 |
| SeungCheon, Y | 1 |
| JeongWon, C | 1 |
| Kyung-Ah, J | 1 |
| Mi-La, C | 1 |
| Sung-Hwan, P | 1 |
| Pablos, JL | 1 |
| Galindo, M | 1 |
| Carmona, L | 1 |
| Lledó, A | 1 |
| Retuerto, M | 1 |
| Blanco, R | 1 |
| Gonzalez-Gay, MA | 1 |
| Martinez-Lopez, D | 1 |
| Castrejón, I | 1 |
| Alvaro-Gracia, JM | 1 |
| Fernández Fernández, D | 1 |
| Mera-Varela, A | 1 |
| Manrique-Arija, S | 1 |
| Mena Vázquez, N | 1 |
| Fernandez-Nebro, A | 1 |
| Shoji, J | 1 |
| Inada, N | 1 |
| Tomioka, A | 1 |
| Yamagami, S | 1 |
| Arakaki, R | 2 |
| Eguchi, H | 1 |
| Yamada, A | 1 |
| Kudo, Y | 1 |
| Iwasa, A | 1 |
| Enkhmaa, T | 1 |
| Hotta, F | 1 |
| Mitamura-Aizawa, S | 1 |
| Mitamura, Y | 1 |
| Hayashi, Y | 2 |
| Ishimaru, N | 2 |
| Arimoto, A | 1 |
| Kitagawa, K | 1 |
| Mita, N | 1 |
| Takahashi, Y | 1 |
| Shibuya, E | 1 |
| Sasaki, H | 1 |
| Kapoor, S | 1 |
| Sugai, S | 1 |
| Takahashi, H | 1 |
| Ohta, S | 1 |
| Nishinarita, M | 1 |
| Takei, M | 1 |
| Sawada, S | 1 |
| Yamaji, K | 1 |
| Oka, H | 1 |
| Umehara, H | 1 |
| Koni, I | 1 |
| Sugiyama, E | 1 |
| Nishiyama, S | 1 |
| Kawakami, A | 1 |
| Kohashi, M | 1 |
| Routsias, JG | 1 |
| Sakarellos-Daitsiotis, M | 1 |
| Tsikaris, V | 1 |
| Sakarellos, C | 1 |
| Moutsopoulos, HM | 1 |
| Tzioufas, AG | 1 |
2 trials available for alanine and Sjogren's Syndrome
| Article | Year |
|---|---|
Assessment of mucin-related gene alterations following treatment with rebamipide ophthalmic suspension in Sjögren's syndrome-associated dry eyes.
Topics: Adult; Aged; Aged, 80 and over; Alanine; CA-125 Antigen; Female; Gene Expression Regulation; Humans; | 2020 |
Efficacy and safety of rebamipide for the treatment of dry mouth symptoms in patients with Sjögren's syndrome: a double-blind placebo-controlled multicenter trial.
Topics: Aged; Alanine; Anti-Inflammatory Agents; Double-Blind Method; Eating; Female; Humans; Male; Middle A | 2009 |
7 other studies available for alanine and Sjogren's Syndrome
| Article | Year |
|---|---|
Immune modulation by rebamipide in a mouse model of Sjogren's syndrome via T and B cell regulation.
Topics: Alanine; Animals; B-Lymphocytes, Regulatory; Cytokines; Disease Models, Animal; Immunomodulation; Mi | 2019 |
Clinical outcomes of hospitalised patients with COVID-19 and chronic inflammatory and autoimmune rheumatic diseases: a multicentric matched cohort study.
Topics: Adenosine Monophosphate; Age Factors; Aged; Alanine; Antiviral Agents; Arthritis, Psoriatic; Arthrit | 2020 |
Anti-inflammatory effects of rebamipide eyedrop administration on ocular lesions in a murine model of primary Sjögren's syndrome.
Topics: Administration, Ophthalmic; Alanine; Animals; Anti-Inflammatory Agents; Cells, Cultured; Disease Mod | 2014 |
Effect of rebamipide ophthalmic suspension on signs and symptoms of keratoconjunctivitis sicca in Sjögren syndrome patients with or without punctal occlusions.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Antibodies, Antinuclear; Antioxidants; Autoantibodies; Eyel | 2014 |
Sjogren's syndrome: promising, new treatment options besides nizatidine.
Topics: Alanine; Antioxidants; Flax; Histamine H2 Antagonists; Humans; Nizatidine; Plant Preparations; Quino | 2009 |
Effective treatment with oral administration of rebamipide in a mouse model of Sjögren's syndrome.
Topics: Administration, Oral; Alanine; Animals; Anti-Inflammatory Agents; Autoantibodies; Cell Division; Cyt | 2008 |
Structural, molecular and immunological properties of linear B-cell epitopes of Ro60KD autoantigen.
Topics: Alanine; Amino Acid Sequence; Autoantigens; Enzyme-Linked Immunosorbent Assay; Epitopes, B-Lymphocyt | 1998 |