alanine has been researched along with Reperfusion Injury in 24 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Safinamide is a newly approved add-on drug to treat Parkinson's disease, and previously studies suggest safinamide could have a potential role on neuroprotection." | 5.56 | The Protective Effect of Safinamide in Ischemic Stroke Mice and a Brain Endothelial Cell Line. ( Kong, S; Sun, R; Wei, G; Xu, T, 2020) |
| "Intraluminal alanine increases the absorptive capacity and energy metabolism of the gut caused by I/R, and indicated that intraluminal glucose improves gut absorptive capacity and energy metabolism and provides a protective effect on gut from ischemia and reperfusion injury." | 3.71 | [Effects of different enteral nutrients on gut absorptive capacity and energy metabolism during gut ischemia/reperfusion]. ( Hu, S; Jiang, X; Liu, Q; Sheng, Z; Shi, D; Sun, D; Zhang, R, 2002) |
| "Safinamide is a newly approved add-on drug to treat Parkinson's disease, and previously studies suggest safinamide could have a potential role on neuroprotection." | 1.56 | The Protective Effect of Safinamide in Ischemic Stroke Mice and a Brain Endothelial Cell Line. ( Kong, S; Sun, R; Wei, G; Xu, T, 2020) |
| "Ischemia/reperfusion injury is mediated by various mechanisms." | 1.35 | Fundamental efforts toward the development of a therapeutic cocktail with a manifold ameliorative effect on hepatic ischemia/reperfusion injury. ( Backhaus, J; Büchler, MW; Flechtenmacher, C; Gebhard, MM; Kincius, M; Liang, R; Schemmer, P; Schindler, G; Zorn, M, 2009) |
| " In order to examine dosage dependency in the effect of MTPG, 4 dosages of MTPG (0." | 1.32 | [Effects of alpha-methyl-(4-tetrazolyl-phenyl) glycine on the induction of hippocampal ischemic tolerance in the rat]. ( Ai, J; Chen, XL; Feng, RF; Li, QJ; Li, WB; Liu, HQ; Zhao, HG; Zhou, AM, 2003) |
| " The Fab' fragment of the antibody was therefore modified with polyethylene glycol (PEG) in order to obtain a more desirable pharmacokinetic profile." | 1.31 | Adapting pharmacokinetic properties of a humanized anti-interleukin-8 antibody for therapeutic applications using site-specific pegylation. ( Chen, H; Chuntharapai, A; DeForge, L; Deveney, J; Fan, A; Galan, W; Gonzalez, T; Gribling, P; Hale, V; Hébert, C; Hsei, V; Kim, KJ; Koumenis, I; Lee, WP; Leong, SR; McKay, P; Narindray, D; Presta, L; Reichert, M; Schoenhoff, M; Shahrokh, Z; Snedecor, B; Tumas, DB; Wagner, B; Zapata, G, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (25.00) | 18.2507 |
| 2000's | 10 (41.67) | 29.6817 |
| 2010's | 5 (20.83) | 24.3611 |
| 2020's | 3 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Hui, B | 1 |
| Shu, Y | 1 |
| Yang, D | 1 |
| Wang, Z | 1 |
| Zhang, L | 1 |
| Lei, N | 1 |
| Yang, Z | 1 |
| Xu, T | 1 |
| Sun, R | 1 |
| Wei, G | 1 |
| Kong, S | 1 |
| Mohr, A | 1 |
| Brockmann, JG | 1 |
| Becker, F | 1 |
| Gendy, AM | 1 |
| Abdallah, DM | 1 |
| El-Abhar, HS | 1 |
| Lautenschläger, I | 1 |
| Pless-Petig, G | 1 |
| Middel, P | 1 |
| de Groot, H | 1 |
| Rauen, U | 1 |
| Stojanovic, T | 1 |
| Chen, L | 1 |
| Luo, Z | 1 |
| Fu, W | 1 |
| Liao, X | 1 |
| Cui, Z | 1 |
| Zhou, J | 1 |
| Nielsen, PM | 1 |
| Laustsen, C | 1 |
| Bertelsen, LB | 1 |
| Qi, H | 1 |
| Mikkelsen, E | 1 |
| Kristensen, ML | 1 |
| Nørregaard, R | 1 |
| Stødkilde-Jørgensen, H | 1 |
| Schindler, G | 1 |
| Kincius, M | 1 |
| Liang, R | 1 |
| Backhaus, J | 1 |
| Zorn, M | 1 |
| Flechtenmacher, C | 1 |
| Gebhard, MM | 1 |
| Büchler, MW | 1 |
| Schemmer, P | 1 |
| Qian, J | 1 |
| Ren, X | 1 |
| Wang, X | 1 |
| Zhang, P | 1 |
| Jones, WK | 1 |
| Molkentin, JD | 1 |
| Fan, GC | 1 |
| Kranias, EG | 1 |
| Kazantzidou, D | 1 |
| Tsalis, K | 1 |
| Vasiliadis, K | 1 |
| Kaldrymidou, H | 1 |
| Papageorgiou, G | 1 |
| Koliakou, K | 1 |
| Tsali, E | 1 |
| Lazaridis, C | 1 |
| Hu, S | 1 |
| Sheng, Z | 1 |
| Liu, Q | 1 |
| Shi, D | 1 |
| Jiang, X | 1 |
| Sun, D | 1 |
| Zhang, R | 1 |
| Kozar, RA | 2 |
| Schultz, SG | 2 |
| Hassoun, HT | 1 |
| Desoignie, R | 2 |
| Weisbrodt, NW | 1 |
| Haber, MM | 1 |
| Moore, FA | 2 |
| Feng, RF | 1 |
| Li, WB | 1 |
| Liu, HQ | 1 |
| Li, QJ | 1 |
| Chen, XL | 1 |
| Zhou, AM | 1 |
| Zhao, HG | 1 |
| Ai, J | 1 |
| Kojima, M | 1 |
| Iwakiri, R | 1 |
| Wu, B | 1 |
| Fujise, T | 1 |
| Watanabe, K | 1 |
| Lin, T | 1 |
| Amemori, S | 1 |
| Sakata, H | 1 |
| Shimoda, R | 1 |
| Oguzu, T | 1 |
| Ootani, A | 1 |
| Tsunada, S | 1 |
| Fujimoto, K | 1 |
| King, N | 1 |
| Lin, H | 1 |
| McGivan, JD | 1 |
| Suleiman, MS | 1 |
| Bick, RJ | 1 |
| Poindexter, BJ | 1 |
| Hiratsuka, T | 1 |
| Futagami, S | 1 |
| Tatsuguchi, A | 1 |
| Suzuki, K | 1 |
| Shinji, Y | 1 |
| Kusunoki, M | 1 |
| Shinoki, K | 1 |
| Nishigaki, H | 1 |
| Fujimori, S | 1 |
| Wada, K | 1 |
| Miyake, K | 1 |
| Gudis, K | 1 |
| Tsukui, T | 1 |
| Sakamoto, C | 1 |
| Kim, CD | 1 |
| Hong, KW | 1 |
| Lee, SM | 1 |
| Kim, KH | 1 |
| Ryan, MG | 1 |
| Balendran, A | 1 |
| Harrison, R | 1 |
| Wolstenholme, A | 1 |
| Bulkley, GB | 1 |
| Kurokawa, T | 1 |
| Joh, T | 1 |
| Ikai, M | 1 |
| Seno, K | 1 |
| Yokoyama, Y | 1 |
| Itoh, M | 1 |
| Patry, J | 1 |
| Adam, R | 1 |
| Dimicoli, JL | 1 |
| Leong, SR | 1 |
| DeForge, L | 1 |
| Presta, L | 1 |
| Gonzalez, T | 1 |
| Fan, A | 1 |
| Reichert, M | 1 |
| Chuntharapai, A | 1 |
| Kim, KJ | 1 |
| Tumas, DB | 1 |
| Lee, WP | 1 |
| Gribling, P | 1 |
| Snedecor, B | 1 |
| Chen, H | 1 |
| Hsei, V | 1 |
| Schoenhoff, M | 1 |
| Hale, V | 1 |
| Deveney, J | 1 |
| Koumenis, I | 1 |
| Shahrokh, Z | 1 |
| McKay, P | 1 |
| Galan, W | 1 |
| Wagner, B | 1 |
| Narindray, D | 1 |
| Hébert, C | 1 |
| Zapata, G | 1 |
| Johnston, JK | 1 |
| Freeman, DE | 1 |
| Gillette, D | 1 |
| Soma, LR | 1 |
1 review available for alanine and Reperfusion Injury
| Article | Year |
|---|---|
HTK-N: Modified Histidine-Tryptophan-Ketoglutarate Solution-A Promising New Tool in Solid Organ Preservation.
Topics: Alanine; Animals; Arginine; Cryopreservation; Glucose; Glycine; Humans; Liver; Mannitol; Organ Prese | 2020 |
23 other studies available for alanine and Reperfusion Injury
| Article | Year |
|---|---|
Sinomenine pretreatment alleviates hepatic ischemia/reperfusion injury through activating Nrf-2/HO-1 pathway.
Topics: Alanine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Caspase 3; Glutathione Peroxida | 2022 |
The Protective Effect of Safinamide in Ischemic Stroke Mice and a Brain Endothelial Cell Line.
Topics: Alanine; Animals; Benzylamines; Blood-Brain Barrier; Brain; Brain Ischemia; Cells, Cultured; Endothe | 2020 |
The potential curative effect of rebamipide in hepatic ischemia/reperfusion injury.
Topics: Alanine; Animals; Apoptosis; Energy Metabolism; Liver; Male; p38 Mitogen-Activated Protein Kinases; | 2017 |
Cold Storage Injury to Rat Small-bowel Transplants-Beneficial Effect of a Modified HTK Solution.
Topics: Alanine; Animals; Cell Hypoxia; Cold Ischemia; Disease Models, Animal; Glucose; Glycine; Humans; Int | 2018 |
Detection of urinary metabolomics before and after Pringle maneuver-induced liver ischemia and reperfusion injury in rats using gas chromatography-mass spectrometry.
Topics: Alanine; Alanine Transaminase; Animals; Bilirubin; Gas Chromatography-Mass Spectrometry; Glycerophos | 2013 |
In situ lactate dehydrogenase activity: a novel renal cortical imaging biomarker of tubular injury?
Topics: Acute Kidney Injury; Alanine; Animals; Bicarbonates; Biomarkers; Carbon Isotopes; Disease Models, An | 2017 |
Fundamental efforts toward the development of a therapeutic cocktail with a manifold ameliorative effect on hepatic ischemia/reperfusion injury.
Topics: Alanine; Animals; Arginine; Chemotaxis, Leukocyte; Clinical Enzyme Tests; Drug Therapy, Combination; | 2009 |
Blockade of Hsp20 phosphorylation exacerbates cardiac ischemia/reperfusion injury by suppressed autophagy and increased cell death.
Topics: Alanine; Animals; Apoptosis; Autophagy; Base Sequence; Disease Models, Animal; Heart Failure; HSP20 | 2009 |
Alanine-glutamine dipeptide pretreatment protects rat renal function from small intestine ischemia-reperfusion injury.
Topics: Alanine; Animals; Dipeptides; Glutamine; Intestine, Small; Male; Rats; Rats, Wistar; Reperfusion Inj | 2010 |
[Effects of different enteral nutrients on gut absorptive capacity and energy metabolism during gut ischemia/reperfusion].
Topics: Adenosine Triphosphate; Alanine; Animals; Energy Metabolism; Enteral Nutrition; Glucose; Intestinal | 2002 |
The type of sodium-coupled solute modulates small bowel mucosal injury, transport function, and ATP after ischemia/reperfusion injury in rats.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Animals; Biological Transport; Drug Combinations; Gluc | 2002 |
[Effects of alpha-methyl-(4-tetrazolyl-phenyl) glycine on the induction of hippocampal ischemic tolerance in the rat].
Topics: Alanine; Animals; Brain Ischemia; Hippocampus; Ischemic Preconditioning; Male; Rats; Rats, Sprague-D | 2003 |
Effects of antioxidative agents on apoptosis induced by ischaemia-reperfusion in rat intestinal mucosa.
Topics: Alanine; Animals; Anti-Ulcer Agents; Antioxidants; Apoptosis; Dimethyl Sulfoxide; Free Radical Scave | 2003 |
Aspartate transporter expression and activity in hypertrophic rat heart and ischaemia-reperfusion injury.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Blotting, | 2004 |
Enteral glutamine but not alanine maintains small bowel barrier function after ischemia/reperfusion injury in rats.
Topics: Alanine; Animals; Calcium Channel Blockers; Cytoskeleton; Glucose; Glutamine; Image Processing, Comp | 2004 |
COX-1 and COX-2 conversely promote and suppress ischemia-reperfusion gastric injury in mice.
Topics: Alanine; Animals; Blotting, Western; Celiac Artery; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygena | 2005 |
Preventive effect of rebamipide on gastric lesions induced by ischemia-reperfusion in the rat.
Topics: Alanine; Animals; Anti-Ulcer Agents; Chemotaxis, Leukocyte; Free Radical Scavengers; Gastric Mucosa; | 1995 |
Rebamipide ameliorates hepatic dysfunction induced by ischemia/reperfusion in rats.
Topics: Alanine; Alanine Transaminase; Allopurinol; Animals; Bile; Enzyme Inhibitors; Free Radical Scavenger | 1995 |
Xanthine oxidoreductase: dehydrogenase to oxidase conversion.
Topics: Alanine; Amino Acid Substitution; Animals; Cloning, Molecular; Liver; Mutagenesis, Site-Directed; Pe | 1997 |
Rebamipide protects against oxygen radical-mediated gastric mucosal injury in rats.
Topics: Alanine; Animals; Antioxidants; Free Radicals; Gastric Mucosa; Male; Oxygen; Quinolones; Rats; Rats, | 1998 |
The effect of dichloroacetate and alanine on the metabolic recovery of perfused mouse liver after cold ischemia.
Topics: Adenosine; Alanine; Allopurinol; Animals; Carbon Isotopes; Cold Temperature; Cryopreservation; Dichl | 1999 |
Adapting pharmacokinetic properties of a humanized anti-interleukin-8 antibody for therapeutic applications using site-specific pegylation.
Topics: Alanine; Animals; Antibodies, Monoclonal; Antigen-Antibody Reactions; DNA, Complementary; Edema; Ele | 2001 |
Effects of superoxide dismutase on injury induced by anoxia and reoxygenation in equine small intestine in vitro.
Topics: Alanine; Animals; Culture Techniques; Female; Horse Diseases; Horses; Hypoxia; Intestinal Obstructio | 1991 |