alanine has been researched along with Pituitary Neoplasms in 4 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rb1(+/-) mice develop pituitary tumors with full penetrance and the tumors are invariably Rb1(-/-), modeling tumorigenesis by two-hit loss of RB1 in humans." | 1.42 | Substituting threonine 187 with alanine in p27Kip1 prevents pituitary tumorigenesis by two-hit loss of Rb1 and enhances humoral immunity in old age. ( Bauzon, F; Bi, E; Cui, J; Fu, H; Jeon, H; Lu, Z; Ye, BH; Yu, JJ; Zang, X; Zhao, H; Zhu, L, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, H | 1 |
| Bauzon, F | 1 |
| Bi, E | 1 |
| Yu, JJ | 1 |
| Fu, H | 1 |
| Lu, Z | 1 |
| Cui, J | 1 |
| Jeon, H | 1 |
| Zang, X | 1 |
| Ye, BH | 1 |
| Zhu, L | 1 |
| Pei, L | 1 |
| Melmed, S | 1 |
| Scheithauer, B | 1 |
| Kovacs, K | 1 |
| Prager, D | 1 |
| Doliński, A | 1 |
| Dunbar, JC | 1 |
| Schultz, S | 1 |
| Houser, F | 1 |
| Walker, J | 1 |
4 other studies available for alanine and Pituitary Neoplasms
| Article | Year |
|---|---|
Substituting threonine 187 with alanine in p27Kip1 prevents pituitary tumorigenesis by two-hit loss of Rb1 and enhances humoral immunity in old age.
Topics: Age Factors; Alanine; Amino Acid Substitution; Animals; B-Lymphocytes; Carcinogenesis; Cyclin-Depend | 2015 |
H-ras mutations in human pituitary carcinoma metastases.
Topics: Adenoma; Alanine; Arginine; Base Sequence; DNA, Neoplasm; Exons; Genes, p53; Genes, ras; Glycine; Hu | 1994 |
Role of alanine in the production of endogenous glucose in patients with intracranial pathology.
Topics: Adenoma; Alanine; Blood Glucose; Brain Damage, Chronic; Brain Death; Brain Diseases; Brain Neoplasms | 1979 |
Regulation of the hepatic response to glucagon: role of insulin, growth hormone and cortisol.
Topics: Alanine; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glucagon; Gluconeogenesis; | 1989 |