Page last updated: 2024-11-08

alanine and Osteoarthritis

alanine has been researched along with Osteoarthritis in 11 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.

Research Excerpts

ExcerptRelevanceReference
"We investigated the correlation of plasma amino acid concentrations and the effects of glucosamine and fish collagen peptide (FCP) on osteoarthritis (OA)."7.79Correlation of plasma amino acid concentrations and chondroprotective effects of glucosamine and fish collagen peptide on the development of osteoarthritis. ( Imagawa, T; Matahira, Y; Minami, S; Ohnishi, A; Okamoto, Y; Osaki, T; Tsuka, T, 2013)
"We investigated the correlation of plasma amino acid concentrations and the effects of glucosamine and fish collagen peptide (FCP) on osteoarthritis (OA)."3.79Correlation of plasma amino acid concentrations and chondroprotective effects of glucosamine and fish collagen peptide on the development of osteoarthritis. ( Imagawa, T; Matahira, Y; Minami, S; Ohnishi, A; Okamoto, Y; Osaki, T; Tsuka, T, 2013)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's1 (9.09)29.6817
2010's8 (72.73)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, TJ1
Kim, ER1
Hong, SN1
Kim, YH1
Lee, YC1
Kim, HS1
Kim, K1
Chang, DK1
Izawa, T2
Hutami, IR2
Tanaka, E2
Vedadghavami, A1
Wagner, EK1
Mehta, S1
He, T1
Zhang, C1
Bajpayee, AG1
Mori, H1
Shinohara, T1
Mino-Oka, A1
Iwasa, A1
Moon, SJ2
Woo, YJ1
Jeong, JH2
Park, MK2
Oh, HJ1
Park, JS2
Kim, EK2
Cho, ML2
Park, SH2
Kim, HY2
Min, JK2
Ohnishi, A1
Osaki, T1
Matahira, Y1
Tsuka, T1
Imagawa, T1
Okamoto, Y1
Minami, S1
Hasegawa, M1
Horiki, N1
Tanaka, K1
Wakabayashi, H1
Tano, S1
Katsurahara, M1
Uchida, A1
Takei, Y1
Sudo, A1
Yang, EJ1
Duffy, JM1
Grimshaw, J1
Guthrie, DJ1
McNally, GM1
Mollan, RA1
Spedding, PL1
Trocha-Grimshaw, J1
Walker, B1
Walsh, E1
Meshitsuka, S1
Yamazaki, E1
Inoue, M1
Hagino, H1
Teshima, R1
Yamamoto, K1
Nentwich, HA1
Mustafa, Z1
Rugg, MS1
Marsden, BD1
Cordell, MR1
Mahoney, DJ1
Jenkins, SC1
Dowling, B1
Fries, E1
Milner, CM1
Loughlin, J1
Day, AJ1

Reviews

1 review available for alanine and Osteoarthritis

ArticleYear
Potential Role of Rebamipide in Osteoclast Differentiation and Mandibular Condylar Cartilage Homeostasis.
    Current rheumatology reviews, 2018, Apr-20, Volume: 14, Issue:1

    Topics: Alanine; Animals; Antioxidants; Cartilage, Articular; Cell Differentiation; Homeostasis; Humans; Man

2018

Trials

1 trial available for alanine and Osteoarthritis

ArticleYear
The efficacy of rebamipide add-on therapy in arthritic patients with COX-2 selective inhibitor-related gastrointestinal events: a prospective, randomized, open-label blinded-endpoint pilot study by the GLORIA study group.
    Modern rheumatology, 2013, Volume: 23, Issue:6

    Topics: Alanine; Arthritis, Rheumatoid; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; E

2013

Other Studies

9 other studies available for alanine and Osteoarthritis

ArticleYear
Effectiveness of acid suppressants and other mucoprotective agents in reducing the risk of occult gastrointestinal bleeding in nonsteroidal anti-inflammatory drug users.
    Scientific reports, 2019, 08-12, Volume: 9, Issue:1

    Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cohort Studies

2019
Cartilage penetrating cationic peptide carriers for applications in drug delivery to avascular negatively charged tissues.
    Acta biomaterialia, 2019, 07-15, Volume: 93

    Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Biological Transport; Cartilage; Cations; Cattle; D

2019
Rebamipide Attenuates Mandibular Condylar Degeneration in a Murine Model of TMJ-OA by Mediating a Chondroprotective Effect and by Downregulating RANKL-Mediated Osteoclastogenesis.
    PloS one, 2016, Volume: 11, Issue:4

    Topics: Administration, Oral; Alanine; Animals; Anti-Inflammatory Agents; Apoptosis; Arthritis, Experimental

2016
Rebamipide attenuates pain severity and cartilage degeneration in a rat model of osteoarthritis by downregulating oxidative damage and catabolic activity in chondrocytes.
    Osteoarthritis and cartilage, 2012, Volume: 20, Issue:11

    Topics: Alanine; Analgesics; Animals; Arthritis, Experimental; Biomarkers; Cartilage, Articular; Cells, Cult

2012
Correlation of plasma amino acid concentrations and chondroprotective effects of glucosamine and fish collagen peptide on the development of osteoarthritis.
    The Journal of veterinary medical science, 2013, May-02, Volume: 75, Issue:4

    Topics: Alanine; Animals; Cartilage, Articular; Collagen; Disease Models, Animal; Female; Glucosamine; Histo

2013
Augmented chondroprotective effect of coadministration of celecoxib and rebamipide in the monosodium iodoacetate rat model of osteoarthritis.
    Archives of pharmacal research, 2013, Volume: 36, Issue:1

    Topics: Administration, Oral; Alanine; Animals; Arthritis, Experimental; Behavior, Animal; Cartilage; Celeco

2013
1H-nuclear magnetic resonance studies of human synovial fluid in arthritic disease states as an aid to confirming metabolic activity in the synovial cavity.
    Clinical science (London, England : 1979), 1993, Volume: 85, Issue:3

    Topics: Acetates; Alanine; Arthritis; Arthritis, Rheumatoid; Diagnosis, Differential; Humans; Hyaluronic Aci

1993
Nuclear magnetic resonance studies of synovial fluids from patients with rheumatoid arthritis and osteoarthritis.
    Clinica chimica acta; international journal of clinical chemistry, 1999, Volume: 281, Issue:1-2

    Topics: Alanine; Arthritis, Rheumatoid; Biomarkers; Diagnosis, Differential; Female; Humans; Lactic Acid; Ma

1999
A novel allelic variant of the human TSG-6 gene encoding an amino acid difference in the CUB module. Chromosomal localization, frequency analysis, modeling, and expression.
    The Journal of biological chemistry, 2002, May-03, Volume: 277, Issue:18

    Topics: Adenine; Alanine; Alleles; Amino Acid Sequence; Amino Acid Substitution; Arginine; Base Sequence; Ce

2002