alanine has been researched along with Necrosis in 20 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Beta-3 thienylalanine, an inhibitor of zymogen formation, was studied in the experimental model of ethionine pancreatitis in the rabbit." | 7.66 | Inhibition of ethionine pancreatitis in the rabbit by DL-BETA-3 thienylalanine pretreatment. ( Guillan, RA; Monto, GL, 1978) |
| " Efficacy against vaginal simian-HIV (SHIV) infection was investigated in six pigtailed macaques that received two tenofovir alafenamide implants (0." | 4.12 | Safety and efficacy of a biodegradable implant releasing tenofovir alafenamide for vaginal protection in a macaque model. ( Dobard, C; García-Lerma, JG; Gary, J; Gatto, G; Heneine, W; Holder, A; Johnson, L; Khalil, G; Krovi, A; Li, L; Luecke, E; Massud, I; Mills, P; Mitchell, J; Nishiura, K; Pan, Y; Ruone, S; van der Straten, A, 2022) |
| " Isoproterenol-induced necrosis of the heart muscle leads to a decrease in both glutamine and alanine ability to bind ammonia (20--40 and 30--45%, respectively)." | 3.66 | [Neutralization of ammonia in cardiac muscle]. ( Minkovskiĭ, EB; Pisarenko, OI; Studneva, IM, 1980) |
| "Beta-3 thienylalanine, an inhibitor of zymogen formation, was studied in the experimental model of ethionine pancreatitis in the rabbit." | 3.66 | Inhibition of ethionine pancreatitis in the rabbit by DL-BETA-3 thienylalanine pretreatment. ( Guillan, RA; Monto, GL, 1978) |
| "Ischemia/reperfusion injury is mediated by various mechanisms." | 1.35 | Fundamental efforts toward the development of a therapeutic cocktail with a manifold ameliorative effect on hepatic ischemia/reperfusion injury. ( Backhaus, J; Büchler, MW; Flechtenmacher, C; Gebhard, MM; Kincius, M; Liang, R; Schemmer, P; Schindler, G; Zorn, M, 2009) |
| "3." | 1.31 | High-resolution magic angle spinning 1H-NMR spectroscopy studies on the renal biochemistry in the bank vole (Clethrionomys glareolus) and the effects of arsenic (As3+) toxicity. ( Griffin, JL; Nicholson, JK; Shore, RF; Walker, L, 2001) |
| ", the LD50 of NBBA was more than 3,000 mg/kg, i." | 1.29 | Protective effect of N-acyl amino acids (NAAs) on cephaloridine (CER) nephrotoxicity in rabbits. ( Hirouchi, Y; Hori, R; Inui, K; Kamiya, A; Kawahara, Y; Naganuma, H; Okada, R, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (30.00) | 18.7374 |
| 1990's | 4 (20.00) | 18.2507 |
| 2000's | 6 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 4 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Massud, I | 1 |
| Krovi, A | 1 |
| Nishiura, K | 1 |
| Ruone, S | 1 |
| Li, L | 1 |
| Holder, A | 1 |
| Gary, J | 1 |
| Mills, P | 1 |
| Mitchell, J | 1 |
| Khalil, G | 1 |
| Pan, Y | 1 |
| Luecke, E | 1 |
| Gatto, G | 1 |
| Heneine, W | 1 |
| García-Lerma, JG | 1 |
| Johnson, L | 1 |
| van der Straten, A | 1 |
| Dobard, C | 1 |
| Su, JT | 1 |
| Simpson, SM | 1 |
| Sung, S | 1 |
| Tfaily, EB | 1 |
| Veazey, R | 1 |
| Marzinke, M | 1 |
| Qiu, J | 1 |
| Watrous, D | 1 |
| Widanapathirana, L | 1 |
| Pearson, E | 1 |
| Peet, MM | 1 |
| Karunakaran, D | 1 |
| Grasperge, B | 1 |
| Dobek, G | 1 |
| Cain, CM | 1 |
| Hope, T | 1 |
| Kiser, PF | 1 |
| Abdel-Wahab, BA | 1 |
| Ali, FEM | 1 |
| Alkahtani, SA | 1 |
| Alshabi, AM | 1 |
| Mahnashi, MH | 1 |
| Hassanein, EHM | 1 |
| Pontolillo, M | 1 |
| Piscitani, L | 1 |
| Ucciferri, C | 1 |
| Di Liberato, L | 1 |
| Bonomini, M | 1 |
| Vecchiet, J | 1 |
| Schindler, G | 1 |
| Kincius, M | 1 |
| Liang, R | 1 |
| Backhaus, J | 1 |
| Zorn, M | 1 |
| Flechtenmacher, C | 1 |
| Gebhard, MM | 1 |
| Büchler, MW | 1 |
| Schemmer, P | 1 |
| Qian, J | 1 |
| Ren, X | 1 |
| Wang, X | 1 |
| Zhang, P | 1 |
| Jones, WK | 1 |
| Molkentin, JD | 1 |
| Fan, GC | 1 |
| Kranias, EG | 1 |
| van den Burg, HA | 1 |
| Westerink, N | 1 |
| Francoijs, KJ | 1 |
| Roth, R | 1 |
| Woestenenk, E | 1 |
| Boeren, S | 1 |
| de Wit, PJ | 1 |
| Joosten, MH | 1 |
| Vervoort, J | 1 |
| Hansen, TL | 1 |
| Christensen, E | 1 |
| Brandt, NJ | 1 |
| Pisarenko, OI | 1 |
| Minkovskiĭ, EB | 1 |
| Studneva, IM | 1 |
| Hirouchi, Y | 2 |
| Naganuma, H | 2 |
| Kawahara, Y | 2 |
| Okada, R | 2 |
| Kamiya, A | 2 |
| Inui, K | 2 |
| Hori, R | 2 |
| Fix, AS | 1 |
| Horn, JW | 1 |
| Hall, RL | 1 |
| Johnson, JA | 1 |
| Tizzano, JP | 1 |
| Dagher, PC | 1 |
| Griffin, JL | 1 |
| Walker, L | 1 |
| Shore, RF | 1 |
| Nicholson, JK | 1 |
| Stoffel, M | 1 |
| Plesnila, N | 1 |
| Eriskat, J | 1 |
| Fürst, M | 1 |
| Baethmann, A | 1 |
| DeVivo, DC | 1 |
| Haymond, MW | 1 |
| Obert, KA | 1 |
| Nelson, JS | 1 |
| Pagliara, AS | 1 |
| Monto, GL | 1 |
| Guillan, RA | 1 |
| Weinberg, JM | 1 |
| Venkatachalam, MA | 1 |
| Garzo-Quintero, R | 1 |
| Roeser, NF | 1 |
| Davis, JA | 1 |
| Camici, P | 1 |
| Marraccini, P | 1 |
| Buzzigoli, G | 1 |
| Boni, C | 1 |
| Ciociaro, D | 1 |
| Maltinti, G | 1 |
| Marzilli, M | 1 |
| Samofalova, MS | 1 |
20 other studies available for alanine and Necrosis
| Article | Year |
|---|---|
Safety and efficacy of a biodegradable implant releasing tenofovir alafenamide for vaginal protection in a macaque model.
Topics: Absorbable Implants; Alanine; Animals; Anti-HIV Agents; Emtricitabine; Female; HIV; HIV Infections; | 2022 |
A Subcutaneous Implant of Tenofovir Alafenamide Fumarate Causes Local Inflammation and Tissue Necrosis in Rabbits and Macaques.
Topics: Adenine; Alanine; Animals; Anti-HIV Agents; Delayed-Action Preparations; Drug Implants; Female; Fuma | 2020 |
Hepatoprotective effect of rebamipide against methotrexate-induced hepatic intoxication: role of Nrf2/GSK-3β, NF-κβ-p65/JAK1/STAT3, and PUMA/Bax/Bcl-2 signaling pathways.
Topics: Alanine; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; | 2020 |
A rare case of acute tubular necrosis tenofovir alafenamide-related.
Topics: Adenine; Alanine; HIV Infections; Humans; Necrosis; Tenofovir | 2021 |
Fundamental efforts toward the development of a therapeutic cocktail with a manifold ameliorative effect on hepatic ischemia/reperfusion injury.
Topics: Alanine; Animals; Arginine; Chemotaxis, Leukocyte; Clinical Enzyme Tests; Drug Therapy, Combination; | 2009 |
Blockade of Hsp20 phosphorylation exacerbates cardiac ischemia/reperfusion injury by suppressed autophagy and increased cell death.
Topics: Alanine; Animals; Apoptosis; Autophagy; Base Sequence; Disease Models, Animal; Heart Failure; HSP20 | 2009 |
Natural disulfide bond-disrupted mutants of AVR4 of the tomato pathogen Cladosporium fulvum are sensitive to proteolysis, circumvent Cf-4-mediated resistance, but retain their chitin binding ability.
Topics: Alanine; Amino Acids; Blood Proteins; Carrier Proteins; Chitin; Chromatography, High Pressure Liquid | 2003 |
Studies on pyruvate carboxylase, pyruvate decarboxylase and lipoamide dehydrogenase in subacute necrotizing encephalomyelopathy.
Topics: Alanine; Brain Diseases; Carboxy-Lyases; Cells, Cultured; Dihydrolipoamide Dehydrogenase; Female; Fi | 1982 |
[Neutralization of ammonia in cardiac muscle].
Topics: Alanine; Ammonia; Animals; Aspartic Acid; Cardiomyopathies; Glutamates; Glutamine; Isoproterenol; Ma | 1980 |
Protective effect of N-acyl amino acids (NAAs) on cephaloridine (CER) nephrotoxicity in rabbits.
Topics: Alanine; Amino Acids; Animals; Cephaloridine; Histocytochemistry; Injections, Intravenous; Kidney Tu | 1993 |
Preventive effect of betamipron on nephrotoxicity and uptake of carbapenems in rabbit renal cortex.
Topics: Alanine; Animals; Carbapenems; Glycosuria, Renal; Imipenem; In Vitro Techniques; Kidney Cortex; Kidn | 1994 |
Progressive retinal toxicity in neonatal rats treated with D,L-2-amino-3-phosphonopropionate (D,L-AP3).
Topics: Alanine; Animals; Animals, Newborn; Cytoplasm; Excitatory Amino Acid Antagonists; Injections, Intrap | 1995 |
Modeling ischemia in vitro: selective depletion of adenine and guanine nucleotide pools.
Topics: Adenosine Triphosphate; Alanine; Animals; Antibiotics, Antineoplastic; Antimycin A; Apoptosis; Cell | 2000 |
High-resolution magic angle spinning 1H-NMR spectroscopy studies on the renal biochemistry in the bank vole (Clethrionomys glareolus) and the effects of arsenic (As3+) toxicity.
Topics: Alanine; Animals; Arsenic; Arvicolinae; Creatine; Glutamic Acid; Glutamine; Kidney; Kidney Diseases; | 2001 |
Release of excitatory amino acids in the penumbra of a focal cortical necrosis.
Topics: Alanine; Animals; Aspartic Acid; Cerebral Cortex; Excitatory Amino Acids; Glutamic Acid; Glycine; Ma | 2002 |
Defective activation of the pyruvate dehydrogenase complex in subacute necrotizing encephalomyelopathy (Leigh disease).
Topics: Alanine; Blood Glucose; Brain; Brain Diseases; Decarboxylation; Dichloroacetic Acid; Enzyme Activati | 1979 |
Inhibition of ethionine pancreatitis in the rabbit by DL-BETA-3 thienylalanine pretreatment.
Topics: Alanine; Amylases; Animals; Cytoplasm; Endoplasmic Reticulum; Ethionine; Male; Necrosis; Pancreatiti | 1978 |
Structural requirements for protection by small amino acids against hypoxic injury in kidney proximal tubules.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Amino Acids, Cyclic; Animals; Dose-Response Relationsh | 1990 |
Is alanine release an early marker of acute myocardial infarction?
Topics: Alanine; Female; Humans; Middle Aged; Myocardial Infarction; Myocardium; Necrosis | 1987 |
[Levels of free amino acids in the blood and heart muscle in the human at various periods of myocardial infarct (clinical anatomical parallels)].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Erythrocytes; Glutamates; Glycine; Hi | 1968 |