Page last updated: 2024-11-08

alanine and Myocardial Infarction

alanine has been researched along with Myocardial Infarction in 48 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).

Research Excerpts

ExcerptRelevanceReference
" Orbofiban, despite no significant excess risk of ICH, was not effective in preventing ischemic stroke or TIA."9.12Risk factors for stroke after acute coronary syndromes in the Orbofiban in Patients with Unstable Coronary Syndromes--Thrombolysis In Myocardial Infarction (OPUS-TIMI) 16 study. ( Cannon, CP; Feske, SK; Murphy, S; Schwamm, LH; Smith, EE, 2006)
"Thrombocytopenia, though uncommon, was associated with orbofiban use and an increased risk of bleeding, but also death and MI."9.12Drug-induced thrombocytopenia and thrombosis: evidence from patients receiving an oral glycoprotein IIb/IIIa inhibitor in the Orbofiban in Patients with Unstable coronary Syndromes- (OPUS-TIMI 16) trial. ( Aster, RH; Brassard, J; Braunwald, E; Cannon, CP; Charlesworth, A; Cooper, R; McCabe, CH; Scirica, BM; Skene, AM, 2006)
"GNB3 genotype distribution was determined in DNA samples from patients in the orbofiban in patients with unstable coronary syndromes-thrombolysis in myocardial infarction (OPUS-TIMI) 16 genetic sub-study."7.76G-protein beta3 subunit polymorphism and bleeding in the orbofiban in patients with unstable coronary syndromes-thrombolysis in myocardial infarction 16 trial. ( Cannon, CP; Cox, D; Fitzgerald, DJ; Jneid, H; Maree, AO; Ryan, J; Shields, DC; Vangjeli, C, 2010)
"The aim of the study was to compare, in a rat model of congestive heart failure, the effect of captopril, a selective angiotensin-converting enzyme (ACE; EC 3."7.69Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril. ( Bralet, J; Gros, C; Lecomte, JM; Marie, C; Mossiat, C; Schwartz, JC, 1994)
"Plasma levels of glutamate, alanine, free fatty acids (FFA), citrate, glucose, insulin, lactate, creatine kinase and aspartate aminotransferase were determined frequently during the first 2-48 h after onset of chest pain in 10 patients who developed acute myocardial infarction (AMI) and in 8 who did not (non-AMI)."7.67Altered plasma concentrations of glutamate, alanine and citrate in the early phase of acute myocardial infarction in man. ( Falstie-Jensen, N; Henningsen, P; Mortensen, PT; Nielsen, TT; Thomassen, AR; Thygesen, K, 1986)
" Orbofiban, despite no significant excess risk of ICH, was not effective in preventing ischemic stroke or TIA."5.12Risk factors for stroke after acute coronary syndromes in the Orbofiban in Patients with Unstable Coronary Syndromes--Thrombolysis In Myocardial Infarction (OPUS-TIMI) 16 study. ( Cannon, CP; Feske, SK; Murphy, S; Schwamm, LH; Smith, EE, 2006)
"Thrombocytopenia, though uncommon, was associated with orbofiban use and an increased risk of bleeding, but also death and MI."5.12Drug-induced thrombocytopenia and thrombosis: evidence from patients receiving an oral glycoprotein IIb/IIIa inhibitor in the Orbofiban in Patients with Unstable coronary Syndromes- (OPUS-TIMI 16) trial. ( Aster, RH; Brassard, J; Braunwald, E; Cannon, CP; Charlesworth, A; Cooper, R; McCabe, CH; Scirica, BM; Skene, AM, 2006)
" The 2 populations studied were as follows: (1) a cross-sectional study of 703 acute coronary syndrome (ACS) patients with myocardial infarction (MI) and unstable angina, and (2) a prospective study of 924 Caucasian patients from the OPUS (Orbofiban in Patients with Unstable coronary Syndromes)-TIMI-16 trial of the oral GPIIb/IIIa antagonist orbofiban."5.10Genetic variability in the extracellular matrix as a determinant of cardiovascular risk: association of type III collagen COL3A1 polymorphisms with coronary artery disease. ( Fitzgerald, A; Fitzgerald, DJ; Muckian, C; O'Byrne, A; O'Neill, A; Shields, DC, 2002)
"GNB3 genotype distribution was determined in DNA samples from patients in the orbofiban in patients with unstable coronary syndromes-thrombolysis in myocardial infarction (OPUS-TIMI) 16 genetic sub-study."3.76G-protein beta3 subunit polymorphism and bleeding in the orbofiban in patients with unstable coronary syndromes-thrombolysis in myocardial infarction 16 trial. ( Cannon, CP; Cox, D; Fitzgerald, DJ; Jneid, H; Maree, AO; Ryan, J; Shields, DC; Vangjeli, C, 2010)
"The aim of the study was to compare, in a rat model of congestive heart failure, the effect of captopril, a selective angiotensin-converting enzyme (ACE; EC 3."3.69Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril. ( Bralet, J; Gros, C; Lecomte, JM; Marie, C; Mossiat, C; Schwartz, JC, 1994)
"Plasma levels of glutamate, alanine, free fatty acids (FFA), citrate, glucose, insulin, lactate, creatine kinase and aspartate aminotransferase were determined frequently during the first 2-48 h after onset of chest pain in 10 patients who developed acute myocardial infarction (AMI) and in 8 who did not (non-AMI)."3.67Altered plasma concentrations of glutamate, alanine and citrate in the early phase of acute myocardial infarction in man. ( Falstie-Jensen, N; Henningsen, P; Mortensen, PT; Nielsen, TT; Thomassen, AR; Thygesen, K, 1986)
"Major or severe bleeding (but not intracranial hemorrhage) was higher with orbofiban; it occurred in 2."2.69Oral glycoprotein IIb/IIIa inhibition with orbofiban in patients with unstable coronary syndromes (OPUS-TIMI 16) trial. ( Alexander, JC; Anders, RJ; Berink, P; Braunwald, E; Cannon, CP; Caspi, A; Charlesworth, A; Langer, A; Lopez-Sendon, J; McCabe, CH; Skene, A; Toman, J; Wilcox, RG, 2000)
" Oral GP IIb/IIIa inhibitors have been associated with an increased incidence of bleeding, but additional experience may permit the design of dosing regimens that decrease this risk."1.31Learning from the recently completed oral glycoprotein IIb/IIIa receptor antagonist trials. ( Cannon, CP, 2000)
"Myocardial infarction was induced by rats by ligation of the left coronary artery."1.29Effect on prolonged inhibition of neutral endopeptidase on cardiac hypertrophy in rats with myocardial infarction. ( Bralet, J; Gros, C; Marie, C; Monteil, T; Mossiat, C, 1996)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-19908 (16.67)18.7374
1990's10 (20.83)18.2507
2000's26 (54.17)29.6817
2010's3 (6.25)24.3611
2020's1 (2.08)2.80

Authors

AuthorsStudies
Colaco, K1
Lee, KA1
Akhtari, S1
Winer, R1
Welsh, P1
Sattar, N1
McInnes, IB1
Chandran, V1
Harvey, P1
Cook, RJ1
Gladman, DD1
Piguet, V1
Eder, L1
Quan, C1
Xie, B1
Wang, HY1
Chen, S1
Maree, AO1
Vangjeli, C1
Jneid, H1
Ryan, J1
Cox, D3
Cannon, CP12
Shields, DC4
Fitzgerald, DJ6
Kariž, S1
Nikolajević Starčević, J1
Petrovič, D1
Muckian, C2
Fitzgerald, A2
O'Neill, A1
O'Byrne, A1
Winter, JP1
Gong, Y1
Grant, PJ1
Wild, CP1
Abuzeid, AM1
Hawe, E1
Humphries, SE1
Talmud, PJ1
COLTORTI, M1
GIUSTI, G1
TRAPANI, A1
ESPOSITO, G1
Kovar, D1
Bentley, JH2
Charlesworth, A4
Rogers, WJ1
Doney, AS1
Fischer, B1
Leese, G1
Morris, AD1
Palmer, CN1
Cui, J1
Randell, E1
Renouf, J1
Sun, G1
Han, FY1
Younghusband, B1
Xie, YG1
Cantor, WJ1
Goodman, SG1
Murphy, SA2
Braunwauld, E1
Langer, A2
Lewandowski, K1
Swierczyńska, A1
Kwaśnikowski, P1
Elikowski, W1
Rzeźniczak, M1
Mager, DE1
Shirey, JD1
Abernethy, DR1
Smith, EE1
Murphy, S2
Feske, SK1
Schwamm, LH1
O'Donoghue, M1
de Lemos, JA2
Morrow, DA2
Buros, JL1
Sabatine, MS3
Li, L1
Cheng, LX1
Nsenga, R1
He, MA1
Wu, TC1
Scirica, BM2
Cooper, R1
Aster, RH1
Brassard, J1
McCabe, CH4
Skene, AM1
Braunwald, E5
März, W1
Seelhorst, U1
Wellnitz, B1
Tiran, B1
Obermayer-Pietsch, B1
Renner, W1
Boehm, BO1
Ritz, E1
Hoffmann, MM1
Wiviott, SD1
Rifai, N1
Bralet, J5
Marie, C5
Mossiat, C5
Lecomte, JM4
Gros, C3
Schwartz, JC3
Gonzalez, W1
Beslot, F1
Laboulandine, I1
Fournié-Zaluski, MC1
Roques, BP1
Michel, JB1
Monteil, T1
Norlund, L1
Holm, J1
Zöller, B1
Ohlin, AK1
Gudnason, V1
Stansbie, D1
Scott, J1
Bowron, A1
Nicaud, V1
Humphries, S1
Hu, K1
Ertl, G1
Wilcox, RG2
Caspi, A1
Berink, P1
Lopez-Sendon, J1
Toman, J1
Anders, RJ1
Alexander, JC1
Skene, A1
Jang, IK1
Newby, LK1
McGuire, DK1
Bhatt, DL2
Topol, EJ2
Smith, R1
Quinn, M1
Theroux, P1
Crean, P1
Chew, DP1
Sapp, S1
Anders, R1
Kleiman, J1
Nicholson, N1
Wazowicz, B1
Burns, D1
O'Connor, FF1
Fitzgerald, AP1
O'Neill, PA1
Kenny, D1
Moran, B1
Byrne, CE1
Trippodo, NC1
Gabel, RA1
Harvey, CM1
Asaad, MM1
Rogers, WL1
Pisarenko, OI1
Studneva, IM1
Thomassen, AR1
Mortensen, PT1
Nielsen, TT1
Falstie-Jensen, N1
Thygesen, K1
Henningsen, P1
Camici, P1
Marraccini, P1
Buzzigoli, G1
Boni, C1
Ciociaro, D1
Maltinti, G1
Marzilli, M1
London, JW1
Yarrish, R1
Dzubow, LD1
Garfinkel, D1
Chazov, E1
Smirnov, VN1
Mazaev, AV1
Asafov, GB1
Gukowski, DU1
Krikov, VI1
Samofalova, MS1
Otto, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Genetics of Diabetes Audit and Research in Tayside Scotland (DOLORisk Dundee)[NCT02783469]1,915 participants (Actual)Observational2004-10-31Completed
In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer[NCT03943966]73 participants (Actual)Interventional2019-11-11Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for alanine and Myocardial Infarction

ArticleYear
The use of glycoprotein IIb/IIIa inhibitors in patients with coronary artery disease.
    The American journal of medicine, 2000, Aug-15, Volume: 109, Issue:3

    Topics: Abciximab; Acetates; Acute Disease; Administration, Oral; Alanine; Angioplasty, Balloon, Coronary; A

2000
Oral platelet glycoprotein IIb/IIIa inhibition.
    Current cardiology reports, 2000, Volume: 2, Issue:5

    Topics: Alanine; Angina, Unstable; Aspirin; Benzamidines; Clinical Trials, Phase II as Topic; Clinical Trial

2000
Current role of platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes.
    JAMA, 2000, Sep-27, Volume: 284, Issue:12

    Topics: Abciximab; Acute Disease; Alanine; Angina, Unstable; Angioplasty, Balloon, Coronary; Antibodies, Mon

2000
Increased mortality with oral platelet glycoprotein IIb/IIIa antagonists: a meta-analysis of phase III multicenter randomized trials.
    Circulation, 2001, Jan-16, Volume: 103, Issue:2

    Topics: Administration, Oral; Alanine; Aspirin; Benzamidines; Clinical Trials, Phase III as Topic; Coronary

2001
Xemilofiban/orbofiban: insight into drug development.
    Cardiovascular drug reviews, 2001,Summer, Volume: 19, Issue:2

    Topics: Alanine; Angina, Unstable; Animals; Benzamidines; Bleeding Time; Clinical Trials, Phase II as Topic;

2001

Trials

11 trials available for alanine and Myocardial Infarction

ArticleYear
Genetic variability in the extracellular matrix as a determinant of cardiovascular risk: association of type III collagen COL3A1 polymorphisms with coronary artery disease.
    Blood, 2002, Aug-15, Volume: 100, Issue:4

    Topics: Alanine; Alleles; Angina, Unstable; Collagen; Collagen Type III; Coronary Disease; Cross-Sectional S

2002
Early cardiac catheterization is associated with lower mortality only among high-risk patients with ST- and non-ST-elevation acute coronary syndromes: observations from the OPUS-TIMI 16 trial.
    American heart journal, 2005, Volume: 149, Issue:2

    Topics: Aged; Alanine; Angina, Unstable; Angioplasty, Balloon, Coronary; Cardiac Catheterization; Coronary A

2005
Risk factors for stroke after acute coronary syndromes in the Orbofiban in Patients with Unstable Coronary Syndromes--Thrombolysis In Myocardial Infarction (OPUS-TIMI) 16 study.
    American heart journal, 2006, Volume: 151, Issue:2

    Topics: Aged; Alanine; Angina, Unstable; Aspirin; Cerebral Hemorrhage; Female; Fibrinolytic Agents; Follow-U

2006
Prognostic utility of heart-type fatty acid binding protein in patients with acute coronary syndromes.
    Circulation, 2006, Aug-08, Volume: 114, Issue:6

    Topics: Acute Disease; Adult; Alanine; Biomarkers; Fatty Acid-Binding Proteins; Female; Heart Failure; Human

2006
Drug-induced thrombocytopenia and thrombosis: evidence from patients receiving an oral glycoprotein IIb/IIIa inhibitor in the Orbofiban in Patients with Unstable coronary Syndromes- (OPUS-TIMI 16) trial.
    Journal of thrombosis and thrombolysis, 2006, Volume: 22, Issue:2

    Topics: Aged; Alanine; Angina, Unstable; Aspirin; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged;

2006
Clinical application of C-reactive protein across the spectrum of acute coronary syndromes.
    Clinical chemistry, 2007, Volume: 53, Issue:10

    Topics: Acute Disease; Aged; Alanine; Angina Pectoris; Angina, Unstable; C-Reactive Protein; Coronary Diseas

2007
Oral glycoprotein IIb/IIIa inhibition with orbofiban in patients with unstable coronary syndromes (OPUS-TIMI 16) trial.
    Circulation, 2000, Jul-11, Volume: 102, Issue:2

    Topics: Administration, Oral; Alanine; Anticoagulants; Aspirin; Coronary Disease; Double-Blind Method; Femal

2000
Evidence of platelet activation during treatment with a GPIIb/IIIa antagonist in patients presenting with acute coronary syndromes.
    Journal of the American College of Cardiology, 2000, Nov-01, Volume: 36, Issue:5

    Topics: Acute Disease; Aged; Alanine; Angina, Unstable; Female; Humans; Male; Myocardial Infarction; Platele

2000
Association of white blood cell count with increased mortality in acute myocardial infarction and unstable angina pectoris. OPUS-TIMI 16 Investigators.
    The American journal of cardiology, 2001, Mar-01, Volume: 87, Issue:5

    Topics: Aged; Alanine; Angina, Unstable; Female; Follow-Up Studies; Humans; Leukocyte Count; Male; Middle Ag

2001
Genetic variation in glycoprotein IIb/IIIa (GPIIb/IIIa) as a determinant of the responses to an oral GPIIb/IIIa antagonist in patients with unstable coronary syndromes.
    Blood, 2001, Dec-01, Volume: 98, Issue:12

    Topics: Aged; Alanine; Angina, Unstable; Antigens, Human Platelet; Aspirin; Double-Blind Method; Female; Gen

2001
The contribution of genetic factors to thrombotic and bleeding outcomes in coronary patients randomised to IIb/IIIa antagonists.
    The pharmacogenomics journal, 2002, Volume: 2, Issue:3

    Topics: Alanine; Coronary Disease; Genotype; Glycoproteins; Hemorrhage; Humans; Myocardial Infarction; Myoca

2002

Other Studies

32 other studies available for alanine and Myocardial Infarction

ArticleYear
Targeted metabolomic profiling and prediction of cardiovascular events: a prospective study of patients with psoriatic arthritis and psoriasis.
    Annals of the rheumatic diseases, 2021, Volume: 80, Issue:11

    Topics: Adult; Alanine; Angina Pectoris; Apolipoproteins B; Arthritis, Psoriatic; Cardiovascular Diseases; C

2021
PKB-Mediated Thr649 Phosphorylation of AS160/TBC1D4 Regulates the R-Wave Amplitude in the Heart.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Alanine; Animals; CD36 Antigens; Electrocardiography; Female; Gene Expression Regulation; Gene Knock

2015
G-protein beta3 subunit polymorphism and bleeding in the orbofiban in patients with unstable coronary syndromes-thrombolysis in myocardial infarction 16 trial.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:5

    Topics: Alanine; Heart Diseases; Heterotrimeric GTP-Binding Proteins; Humans; Myocardial Infarction; Polymor

2010
Association of manganese superoxide dismutase and glutathione S-transferases genotypes with myocardial infarction in patients with type 2 diabetes mellitus.
    Diabetes research and clinical practice, 2012, Volume: 98, Issue:1

    Topics: Alanine; Biomarkers; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Ang

2012
Glutathione peroxidase 1 genotype is associated with an increased risk of coronary artery disease.
    Coronary artery disease, 2003, Volume: 14, Issue:2

    Topics: Alanine; Alleles; Blood Pressure; Body Mass Index; Case-Control Studies; Coronary Artery Disease; Di

2003
Association between the Ala379Val variant of the lipoprotein associated phospholipase A2 and risk of myocardial infarction in the north and south of Europe.
    Atherosclerosis, 2003, Volume: 168, Issue:2

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Alanine; Alleles; Case-Control Studies; Europe; Gene

2003
[Behavior of serum aspartic-ketoglutaric and alanine-ketoglutaric transaminases in experimental myocardial infarct].
    Minerva cardioangiologica, 1957, Volume: 5, Issue:3

    Topics: Alanine; Humans; Myocardial Infarction; Transaminases

1957
Does initial and delayed heart rate predict mortality in patients with acute coronary syndromes?
    Clinical cardiology, 2004, Volume: 27, Issue:2

    Topics: Acute Disease; Alanine; Female; Heart Rate; Humans; Male; Middle Aged; Myocardial Infarction; Platel

2004
Cardiovascular risk in type 2 diabetes is associated with variation at the PPARG locus: a Go-DARTS study.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:12

    Topics: Age Factors; Alanine; Alleles; Amino Acid Substitution; Cardiovascular Diseases; Cohort Studies; Cyt

2004
Gender dependent association of thrombospondin-4 A387P polymorphism with myocardial infarction.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:11

    Topics: Alanine; Amino Acid Substitution; Case-Control Studies; Female; Humans; Male; Middle Aged; Myocardia

2004
The prevalence of C807T mutation of glycoprotein Ia gene among young male survivors of myocardial infarction: a relation with coronary angiography results.
    Kardiologia polska, 2005, Volume: 63, Issue:2

    Topics: Adult; Alanine; Case-Control Studies; Coronary Angiography; Cysteine; Gene Expression; Gene Frequenc

2005
Mapping the dose-effect relationship of orbofiban from sparse data with an artificial neural network.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:11

    Topics: Alanine; Angina, Unstable; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Male;

2005
Association between Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma 2 and myocardial infarction in the Chinese Han population.
    Clinical cardiology, 2006, Volume: 29, Issue:7

    Topics: Aged; Alanine; Asian People; Electrophoresis; Female; Gene Frequency; Genotype; Humans; Male; Middle

2006
Alanine to serine polymorphism at position 986 of the calcium-sensing receptor associated with coronary heart disease, myocardial infarction, all-cause, and cardiovascular mortality.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:6

    Topics: Adult; Aged; Alanine; Calcium; Cause of Death; Coronary Angiography; Coronary Disease; Female; Genet

2007
Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1

    Topics: Alanine; Amino Acid Sequence; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Atri

1994
Hemodynamic effects of acute and chronic treatment with aladotril, a mixed inhibitor of neutral endopeptidase and angiotensin I-converting enzyme, in conscious rats with myocardial infarction.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:3

    Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Heart; Hemodynamics; Male; My

1995
Inhibition of both angiotensin-converting enzyme and neutral endopeptidase by S21402 (RB105) in rats with experimental myocardial infarction.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:2

    Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal;

1996
Effect on prolonged inhibition of neutral endopeptidase on cardiac hypertrophy in rats with myocardial infarction.
    Cardiovascular drugs and therapy, 1996, Volume: 10, Issue:5

    Topics: Alanine; Animals; Atrial Natriuretic Factor; Cardiomegaly; Enzyme Inhibitors; Ligation; Male; Myocar

1996
A common thrombomodulin amino acid dimorphism is associated with myocardial infarction.
    Thrombosis and haemostasis, 1997, Volume: 77, Issue:2

    Topics: Adult; Age of Onset; Alanine; Alleles; Codon; Disease Susceptibility; DNA Mutational Analysis; Femal

1997
C677T (thermolabile alanine/valine) polymorphism in methylenetetrahydrofolate reductase (MTHFR): its frequency and impact on plasma homocysteine concentration in different European populations. EARS group.
    Atherosclerosis, 1998, Volume: 136, Issue:2

    Topics: Adolescent; Adult; Alanine; Alleles; Europe; Gene Frequency; Genetics, Population; Genotype; Heteroz

1998
Acute natriuretic effect of fasidotrilat, a mixed inhibitor of neutral endopeptidase and angiotensin I-converting enzyme, in rats with heart failure.
    Pharmacology, 1998, Volume: 56, Issue:6

    Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Diuresis; Enzyme Inhibit

1998
Potential role of mixed ACE and neutral endopeptidase inhibitor in the treatment of heart failure.
    Cardiovascular research, 1999, Volume: 41, Issue:3

    Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiomegaly; Cricetinae

1999
Effect of long-term therapy with fasidotril, a mixed inhibitor of neprilysin and angiotensin-converting enzyme (ACE), on survival of rats after myocardial infarction.
    Cardiovascular research, 1999, Volume: 41, Issue:3

    Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Chi-Square Distribution;

1999
Learning from the recently completed oral glycoprotein IIb/IIIa receptor antagonist trials.
    Clinical cardiology, 2000, Volume: 23 Suppl 6

    Topics: Alanine; Angina, Unstable; Benzamidines; Humans; Myocardial Infarction; Platelet Aggregation Inhibit

2000
Heart failure augments the cardiovascular and renal effects of neutral endopeptidase inhibition in rats.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:3

    Topics: Alanine; Animals; Blood Pressure; Body Weight; Central Venous Pressure; Heart Failure; Heart Rate; H

1991
[Mechanisms of ammonia binding in the heart muscle].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1985, Volume: 8, Issue:2

    Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Glutamine; In Vitr

1985
Altered plasma concentrations of glutamate, alanine and citrate in the early phase of acute myocardial infarction in man.
    European heart journal, 1986, Volume: 7, Issue:9

    Topics: Aged; Alanine; Blood Glucose; Citrates; Citric Acid; Digoxin; Fatty Acids, Nonesterified; Glutamates

1986
Is alanine release an early marker of acute myocardial infarction?
    European heart journal, 1987, Volume: 8, Issue:2

    Topics: Alanine; Female; Humans; Middle Aged; Myocardial Infarction; Myocardium; Necrosis

1987
Computer simulation and optimization, as exemplified by the enzyme-coupled aminotransferase (transaminase) assays.
    Clinical chemistry, 1974, Volume: 20, Issue:11

    Topics: Alanine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspartic Acid; Computers; Evalu

1974
Myocardial ammonia metabolism in patients with heart disease as revealed by coronary sinus catheterization study.
    Circulation, 1973, Volume: 47, Issue:6

    Topics: Adult; Alanine; Ammonia; Cardiac Catheterization; Cineangiography; Coronary Angiography; Coronary Di

1973
[Levels of free amino acids in the blood and heart muscle in the human at various periods of myocardial infarct (clinical anatomical parallels)].
    Kardiologiia, 1968, Volume: 8, Issue:11

    Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Erythrocytes; Glutamates; Glycine; Hi

1968
[Increased transaminase activity in acute hepatitis, myocardial infarct and other diseases].
    Medizinische Monatsschrift, 1966, Volume: 20, Issue:8

    Topics: Alanine; Aspartate Aminotransferases; Hepatitis A; Humans; Myocardial Infarction; Pancreatitis

1966