alanine has been researched along with Myocardial Infarction in 48 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
Excerpt | Relevance | Reference |
---|---|---|
" Orbofiban, despite no significant excess risk of ICH, was not effective in preventing ischemic stroke or TIA." | 9.12 | Risk factors for stroke after acute coronary syndromes in the Orbofiban in Patients with Unstable Coronary Syndromes--Thrombolysis In Myocardial Infarction (OPUS-TIMI) 16 study. ( Cannon, CP; Feske, SK; Murphy, S; Schwamm, LH; Smith, EE, 2006) |
"Thrombocytopenia, though uncommon, was associated with orbofiban use and an increased risk of bleeding, but also death and MI." | 9.12 | Drug-induced thrombocytopenia and thrombosis: evidence from patients receiving an oral glycoprotein IIb/IIIa inhibitor in the Orbofiban in Patients with Unstable coronary Syndromes- (OPUS-TIMI 16) trial. ( Aster, RH; Brassard, J; Braunwald, E; Cannon, CP; Charlesworth, A; Cooper, R; McCabe, CH; Scirica, BM; Skene, AM, 2006) |
"GNB3 genotype distribution was determined in DNA samples from patients in the orbofiban in patients with unstable coronary syndromes-thrombolysis in myocardial infarction (OPUS-TIMI) 16 genetic sub-study." | 7.76 | G-protein beta3 subunit polymorphism and bleeding in the orbofiban in patients with unstable coronary syndromes-thrombolysis in myocardial infarction 16 trial. ( Cannon, CP; Cox, D; Fitzgerald, DJ; Jneid, H; Maree, AO; Ryan, J; Shields, DC; Vangjeli, C, 2010) |
"The aim of the study was to compare, in a rat model of congestive heart failure, the effect of captopril, a selective angiotensin-converting enzyme (ACE; EC 3." | 7.69 | Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril. ( Bralet, J; Gros, C; Lecomte, JM; Marie, C; Mossiat, C; Schwartz, JC, 1994) |
"Plasma levels of glutamate, alanine, free fatty acids (FFA), citrate, glucose, insulin, lactate, creatine kinase and aspartate aminotransferase were determined frequently during the first 2-48 h after onset of chest pain in 10 patients who developed acute myocardial infarction (AMI) and in 8 who did not (non-AMI)." | 7.67 | Altered plasma concentrations of glutamate, alanine and citrate in the early phase of acute myocardial infarction in man. ( Falstie-Jensen, N; Henningsen, P; Mortensen, PT; Nielsen, TT; Thomassen, AR; Thygesen, K, 1986) |
" Orbofiban, despite no significant excess risk of ICH, was not effective in preventing ischemic stroke or TIA." | 5.12 | Risk factors for stroke after acute coronary syndromes in the Orbofiban in Patients with Unstable Coronary Syndromes--Thrombolysis In Myocardial Infarction (OPUS-TIMI) 16 study. ( Cannon, CP; Feske, SK; Murphy, S; Schwamm, LH; Smith, EE, 2006) |
"Thrombocytopenia, though uncommon, was associated with orbofiban use and an increased risk of bleeding, but also death and MI." | 5.12 | Drug-induced thrombocytopenia and thrombosis: evidence from patients receiving an oral glycoprotein IIb/IIIa inhibitor in the Orbofiban in Patients with Unstable coronary Syndromes- (OPUS-TIMI 16) trial. ( Aster, RH; Brassard, J; Braunwald, E; Cannon, CP; Charlesworth, A; Cooper, R; McCabe, CH; Scirica, BM; Skene, AM, 2006) |
" The 2 populations studied were as follows: (1) a cross-sectional study of 703 acute coronary syndrome (ACS) patients with myocardial infarction (MI) and unstable angina, and (2) a prospective study of 924 Caucasian patients from the OPUS (Orbofiban in Patients with Unstable coronary Syndromes)-TIMI-16 trial of the oral GPIIb/IIIa antagonist orbofiban." | 5.10 | Genetic variability in the extracellular matrix as a determinant of cardiovascular risk: association of type III collagen COL3A1 polymorphisms with coronary artery disease. ( Fitzgerald, A; Fitzgerald, DJ; Muckian, C; O'Byrne, A; O'Neill, A; Shields, DC, 2002) |
"GNB3 genotype distribution was determined in DNA samples from patients in the orbofiban in patients with unstable coronary syndromes-thrombolysis in myocardial infarction (OPUS-TIMI) 16 genetic sub-study." | 3.76 | G-protein beta3 subunit polymorphism and bleeding in the orbofiban in patients with unstable coronary syndromes-thrombolysis in myocardial infarction 16 trial. ( Cannon, CP; Cox, D; Fitzgerald, DJ; Jneid, H; Maree, AO; Ryan, J; Shields, DC; Vangjeli, C, 2010) |
"The aim of the study was to compare, in a rat model of congestive heart failure, the effect of captopril, a selective angiotensin-converting enzyme (ACE; EC 3." | 3.69 | Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril. ( Bralet, J; Gros, C; Lecomte, JM; Marie, C; Mossiat, C; Schwartz, JC, 1994) |
"Plasma levels of glutamate, alanine, free fatty acids (FFA), citrate, glucose, insulin, lactate, creatine kinase and aspartate aminotransferase were determined frequently during the first 2-48 h after onset of chest pain in 10 patients who developed acute myocardial infarction (AMI) and in 8 who did not (non-AMI)." | 3.67 | Altered plasma concentrations of glutamate, alanine and citrate in the early phase of acute myocardial infarction in man. ( Falstie-Jensen, N; Henningsen, P; Mortensen, PT; Nielsen, TT; Thomassen, AR; Thygesen, K, 1986) |
"Major or severe bleeding (but not intracranial hemorrhage) was higher with orbofiban; it occurred in 2." | 2.69 | Oral glycoprotein IIb/IIIa inhibition with orbofiban in patients with unstable coronary syndromes (OPUS-TIMI 16) trial. ( Alexander, JC; Anders, RJ; Berink, P; Braunwald, E; Cannon, CP; Caspi, A; Charlesworth, A; Langer, A; Lopez-Sendon, J; McCabe, CH; Skene, A; Toman, J; Wilcox, RG, 2000) |
" Oral GP IIb/IIIa inhibitors have been associated with an increased incidence of bleeding, but additional experience may permit the design of dosing regimens that decrease this risk." | 1.31 | Learning from the recently completed oral glycoprotein IIb/IIIa receptor antagonist trials. ( Cannon, CP, 2000) |
"Myocardial infarction was induced by rats by ligation of the left coronary artery." | 1.29 | Effect on prolonged inhibition of neutral endopeptidase on cardiac hypertrophy in rats with myocardial infarction. ( Bralet, J; Gros, C; Marie, C; Monteil, T; Mossiat, C, 1996) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (16.67) | 18.7374 |
1990's | 10 (20.83) | 18.2507 |
2000's | 26 (54.17) | 29.6817 |
2010's | 3 (6.25) | 24.3611 |
2020's | 1 (2.08) | 2.80 |
Authors | Studies |
---|---|
Colaco, K | 1 |
Lee, KA | 1 |
Akhtari, S | 1 |
Winer, R | 1 |
Welsh, P | 1 |
Sattar, N | 1 |
McInnes, IB | 1 |
Chandran, V | 1 |
Harvey, P | 1 |
Cook, RJ | 1 |
Gladman, DD | 1 |
Piguet, V | 1 |
Eder, L | 1 |
Quan, C | 1 |
Xie, B | 1 |
Wang, HY | 1 |
Chen, S | 1 |
Maree, AO | 1 |
Vangjeli, C | 1 |
Jneid, H | 1 |
Ryan, J | 1 |
Cox, D | 3 |
Cannon, CP | 12 |
Shields, DC | 4 |
Fitzgerald, DJ | 6 |
Kariž, S | 1 |
Nikolajević Starčević, J | 1 |
Petrovič, D | 1 |
Muckian, C | 2 |
Fitzgerald, A | 2 |
O'Neill, A | 1 |
O'Byrne, A | 1 |
Winter, JP | 1 |
Gong, Y | 1 |
Grant, PJ | 1 |
Wild, CP | 1 |
Abuzeid, AM | 1 |
Hawe, E | 1 |
Humphries, SE | 1 |
Talmud, PJ | 1 |
COLTORTI, M | 1 |
GIUSTI, G | 1 |
TRAPANI, A | 1 |
ESPOSITO, G | 1 |
Kovar, D | 1 |
Bentley, JH | 2 |
Charlesworth, A | 4 |
Rogers, WJ | 1 |
Doney, AS | 1 |
Fischer, B | 1 |
Leese, G | 1 |
Morris, AD | 1 |
Palmer, CN | 1 |
Cui, J | 1 |
Randell, E | 1 |
Renouf, J | 1 |
Sun, G | 1 |
Han, FY | 1 |
Younghusband, B | 1 |
Xie, YG | 1 |
Cantor, WJ | 1 |
Goodman, SG | 1 |
Murphy, SA | 2 |
Braunwauld, E | 1 |
Langer, A | 2 |
Lewandowski, K | 1 |
Swierczyńska, A | 1 |
Kwaśnikowski, P | 1 |
Elikowski, W | 1 |
Rzeźniczak, M | 1 |
Mager, DE | 1 |
Shirey, JD | 1 |
Abernethy, DR | 1 |
Smith, EE | 1 |
Murphy, S | 2 |
Feske, SK | 1 |
Schwamm, LH | 1 |
O'Donoghue, M | 1 |
de Lemos, JA | 2 |
Morrow, DA | 2 |
Buros, JL | 1 |
Sabatine, MS | 3 |
Li, L | 1 |
Cheng, LX | 1 |
Nsenga, R | 1 |
He, MA | 1 |
Wu, TC | 1 |
Scirica, BM | 2 |
Cooper, R | 1 |
Aster, RH | 1 |
Brassard, J | 1 |
McCabe, CH | 4 |
Skene, AM | 1 |
Braunwald, E | 5 |
März, W | 1 |
Seelhorst, U | 1 |
Wellnitz, B | 1 |
Tiran, B | 1 |
Obermayer-Pietsch, B | 1 |
Renner, W | 1 |
Boehm, BO | 1 |
Ritz, E | 1 |
Hoffmann, MM | 1 |
Wiviott, SD | 1 |
Rifai, N | 1 |
Bralet, J | 5 |
Marie, C | 5 |
Mossiat, C | 5 |
Lecomte, JM | 4 |
Gros, C | 3 |
Schwartz, JC | 3 |
Gonzalez, W | 1 |
Beslot, F | 1 |
Laboulandine, I | 1 |
Fournié-Zaluski, MC | 1 |
Roques, BP | 1 |
Michel, JB | 1 |
Monteil, T | 1 |
Norlund, L | 1 |
Holm, J | 1 |
Zöller, B | 1 |
Ohlin, AK | 1 |
Gudnason, V | 1 |
Stansbie, D | 1 |
Scott, J | 1 |
Bowron, A | 1 |
Nicaud, V | 1 |
Humphries, S | 1 |
Hu, K | 1 |
Ertl, G | 1 |
Wilcox, RG | 2 |
Caspi, A | 1 |
Berink, P | 1 |
Lopez-Sendon, J | 1 |
Toman, J | 1 |
Anders, RJ | 1 |
Alexander, JC | 1 |
Skene, A | 1 |
Jang, IK | 1 |
Newby, LK | 1 |
McGuire, DK | 1 |
Bhatt, DL | 2 |
Topol, EJ | 2 |
Smith, R | 1 |
Quinn, M | 1 |
Theroux, P | 1 |
Crean, P | 1 |
Chew, DP | 1 |
Sapp, S | 1 |
Anders, R | 1 |
Kleiman, J | 1 |
Nicholson, N | 1 |
Wazowicz, B | 1 |
Burns, D | 1 |
O'Connor, FF | 1 |
Fitzgerald, AP | 1 |
O'Neill, PA | 1 |
Kenny, D | 1 |
Moran, B | 1 |
Byrne, CE | 1 |
Trippodo, NC | 1 |
Gabel, RA | 1 |
Harvey, CM | 1 |
Asaad, MM | 1 |
Rogers, WL | 1 |
Pisarenko, OI | 1 |
Studneva, IM | 1 |
Thomassen, AR | 1 |
Mortensen, PT | 1 |
Nielsen, TT | 1 |
Falstie-Jensen, N | 1 |
Thygesen, K | 1 |
Henningsen, P | 1 |
Camici, P | 1 |
Marraccini, P | 1 |
Buzzigoli, G | 1 |
Boni, C | 1 |
Ciociaro, D | 1 |
Maltinti, G | 1 |
Marzilli, M | 1 |
London, JW | 1 |
Yarrish, R | 1 |
Dzubow, LD | 1 |
Garfinkel, D | 1 |
Chazov, E | 1 |
Smirnov, VN | 1 |
Mazaev, AV | 1 |
Asafov, GB | 1 |
Gukowski, DU | 1 |
Krikov, VI | 1 |
Samofalova, MS | 1 |
Otto, H | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Genetics of Diabetes Audit and Research in Tayside Scotland (DOLORisk Dundee)[NCT02783469] | 1,915 participants (Actual) | Observational | 2004-10-31 | Completed | |||
In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer[NCT03943966] | 73 participants (Actual) | Interventional | 2019-11-11 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
5 reviews available for alanine and Myocardial Infarction
Article | Year |
---|---|
The use of glycoprotein IIb/IIIa inhibitors in patients with coronary artery disease.
Topics: Abciximab; Acetates; Acute Disease; Administration, Oral; Alanine; Angioplasty, Balloon, Coronary; A | 2000 |
Oral platelet glycoprotein IIb/IIIa inhibition.
Topics: Alanine; Angina, Unstable; Aspirin; Benzamidines; Clinical Trials, Phase II as Topic; Clinical Trial | 2000 |
Current role of platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes.
Topics: Abciximab; Acute Disease; Alanine; Angina, Unstable; Angioplasty, Balloon, Coronary; Antibodies, Mon | 2000 |
Increased mortality with oral platelet glycoprotein IIb/IIIa antagonists: a meta-analysis of phase III multicenter randomized trials.
Topics: Administration, Oral; Alanine; Aspirin; Benzamidines; Clinical Trials, Phase III as Topic; Coronary | 2001 |
Xemilofiban/orbofiban: insight into drug development.
Topics: Alanine; Angina, Unstable; Animals; Benzamidines; Bleeding Time; Clinical Trials, Phase II as Topic; | 2001 |
11 trials available for alanine and Myocardial Infarction
Article | Year |
---|---|
Genetic variability in the extracellular matrix as a determinant of cardiovascular risk: association of type III collagen COL3A1 polymorphisms with coronary artery disease.
Topics: Alanine; Alleles; Angina, Unstable; Collagen; Collagen Type III; Coronary Disease; Cross-Sectional S | 2002 |
Early cardiac catheterization is associated with lower mortality only among high-risk patients with ST- and non-ST-elevation acute coronary syndromes: observations from the OPUS-TIMI 16 trial.
Topics: Aged; Alanine; Angina, Unstable; Angioplasty, Balloon, Coronary; Cardiac Catheterization; Coronary A | 2005 |
Risk factors for stroke after acute coronary syndromes in the Orbofiban in Patients with Unstable Coronary Syndromes--Thrombolysis In Myocardial Infarction (OPUS-TIMI) 16 study.
Topics: Aged; Alanine; Angina, Unstable; Aspirin; Cerebral Hemorrhage; Female; Fibrinolytic Agents; Follow-U | 2006 |
Prognostic utility of heart-type fatty acid binding protein in patients with acute coronary syndromes.
Topics: Acute Disease; Adult; Alanine; Biomarkers; Fatty Acid-Binding Proteins; Female; Heart Failure; Human | 2006 |
Drug-induced thrombocytopenia and thrombosis: evidence from patients receiving an oral glycoprotein IIb/IIIa inhibitor in the Orbofiban in Patients with Unstable coronary Syndromes- (OPUS-TIMI 16) trial.
Topics: Aged; Alanine; Angina, Unstable; Aspirin; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; | 2006 |
Clinical application of C-reactive protein across the spectrum of acute coronary syndromes.
Topics: Acute Disease; Aged; Alanine; Angina Pectoris; Angina, Unstable; C-Reactive Protein; Coronary Diseas | 2007 |
Oral glycoprotein IIb/IIIa inhibition with orbofiban in patients with unstable coronary syndromes (OPUS-TIMI 16) trial.
Topics: Administration, Oral; Alanine; Anticoagulants; Aspirin; Coronary Disease; Double-Blind Method; Femal | 2000 |
Evidence of platelet activation during treatment with a GPIIb/IIIa antagonist in patients presenting with acute coronary syndromes.
Topics: Acute Disease; Aged; Alanine; Angina, Unstable; Female; Humans; Male; Myocardial Infarction; Platele | 2000 |
Association of white blood cell count with increased mortality in acute myocardial infarction and unstable angina pectoris. OPUS-TIMI 16 Investigators.
Topics: Aged; Alanine; Angina, Unstable; Female; Follow-Up Studies; Humans; Leukocyte Count; Male; Middle Ag | 2001 |
Genetic variation in glycoprotein IIb/IIIa (GPIIb/IIIa) as a determinant of the responses to an oral GPIIb/IIIa antagonist in patients with unstable coronary syndromes.
Topics: Aged; Alanine; Angina, Unstable; Antigens, Human Platelet; Aspirin; Double-Blind Method; Female; Gen | 2001 |
The contribution of genetic factors to thrombotic and bleeding outcomes in coronary patients randomised to IIb/IIIa antagonists.
Topics: Alanine; Coronary Disease; Genotype; Glycoproteins; Hemorrhage; Humans; Myocardial Infarction; Myoca | 2002 |
32 other studies available for alanine and Myocardial Infarction
Article | Year |
---|---|
Targeted metabolomic profiling and prediction of cardiovascular events: a prospective study of patients with psoriatic arthritis and psoriasis.
Topics: Adult; Alanine; Angina Pectoris; Apolipoproteins B; Arthritis, Psoriatic; Cardiovascular Diseases; C | 2021 |
PKB-Mediated Thr649 Phosphorylation of AS160/TBC1D4 Regulates the R-Wave Amplitude in the Heart.
Topics: Alanine; Animals; CD36 Antigens; Electrocardiography; Female; Gene Expression Regulation; Gene Knock | 2015 |
G-protein beta3 subunit polymorphism and bleeding in the orbofiban in patients with unstable coronary syndromes-thrombolysis in myocardial infarction 16 trial.
Topics: Alanine; Heart Diseases; Heterotrimeric GTP-Binding Proteins; Humans; Myocardial Infarction; Polymor | 2010 |
Association of manganese superoxide dismutase and glutathione S-transferases genotypes with myocardial infarction in patients with type 2 diabetes mellitus.
Topics: Alanine; Biomarkers; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Ang | 2012 |
Glutathione peroxidase 1 genotype is associated with an increased risk of coronary artery disease.
Topics: Alanine; Alleles; Blood Pressure; Body Mass Index; Case-Control Studies; Coronary Artery Disease; Di | 2003 |
Association between the Ala379Val variant of the lipoprotein associated phospholipase A2 and risk of myocardial infarction in the north and south of Europe.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Alanine; Alleles; Case-Control Studies; Europe; Gene | 2003 |
[Behavior of serum aspartic-ketoglutaric and alanine-ketoglutaric transaminases in experimental myocardial infarct].
Topics: Alanine; Humans; Myocardial Infarction; Transaminases | 1957 |
Does initial and delayed heart rate predict mortality in patients with acute coronary syndromes?
Topics: Acute Disease; Alanine; Female; Heart Rate; Humans; Male; Middle Aged; Myocardial Infarction; Platel | 2004 |
Cardiovascular risk in type 2 diabetes is associated with variation at the PPARG locus: a Go-DARTS study.
Topics: Age Factors; Alanine; Alleles; Amino Acid Substitution; Cardiovascular Diseases; Cohort Studies; Cyt | 2004 |
Gender dependent association of thrombospondin-4 A387P polymorphism with myocardial infarction.
Topics: Alanine; Amino Acid Substitution; Case-Control Studies; Female; Humans; Male; Middle Aged; Myocardia | 2004 |
The prevalence of C807T mutation of glycoprotein Ia gene among young male survivors of myocardial infarction: a relation with coronary angiography results.
Topics: Adult; Alanine; Case-Control Studies; Coronary Angiography; Cysteine; Gene Expression; Gene Frequenc | 2005 |
Mapping the dose-effect relationship of orbofiban from sparse data with an artificial neural network.
Topics: Alanine; Angina, Unstable; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Male; | 2005 |
Association between Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma 2 and myocardial infarction in the Chinese Han population.
Topics: Aged; Alanine; Asian People; Electrophoresis; Female; Gene Frequency; Genotype; Humans; Male; Middle | 2006 |
Alanine to serine polymorphism at position 986 of the calcium-sensing receptor associated with coronary heart disease, myocardial infarction, all-cause, and cardiovascular mortality.
Topics: Adult; Aged; Alanine; Calcium; Cause of Death; Coronary Angiography; Coronary Disease; Female; Genet | 2007 |
Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril.
Topics: Alanine; Amino Acid Sequence; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Atri | 1994 |
Hemodynamic effects of acute and chronic treatment with aladotril, a mixed inhibitor of neutral endopeptidase and angiotensin I-converting enzyme, in conscious rats with myocardial infarction.
Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Heart; Hemodynamics; Male; My | 1995 |
Inhibition of both angiotensin-converting enzyme and neutral endopeptidase by S21402 (RB105) in rats with experimental myocardial infarction.
Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; | 1996 |
Effect on prolonged inhibition of neutral endopeptidase on cardiac hypertrophy in rats with myocardial infarction.
Topics: Alanine; Animals; Atrial Natriuretic Factor; Cardiomegaly; Enzyme Inhibitors; Ligation; Male; Myocar | 1996 |
A common thrombomodulin amino acid dimorphism is associated with myocardial infarction.
Topics: Adult; Age of Onset; Alanine; Alleles; Codon; Disease Susceptibility; DNA Mutational Analysis; Femal | 1997 |
C677T (thermolabile alanine/valine) polymorphism in methylenetetrahydrofolate reductase (MTHFR): its frequency and impact on plasma homocysteine concentration in different European populations. EARS group.
Topics: Adolescent; Adult; Alanine; Alleles; Europe; Gene Frequency; Genetics, Population; Genotype; Heteroz | 1998 |
Acute natriuretic effect of fasidotrilat, a mixed inhibitor of neutral endopeptidase and angiotensin I-converting enzyme, in rats with heart failure.
Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Diuresis; Enzyme Inhibit | 1998 |
Potential role of mixed ACE and neutral endopeptidase inhibitor in the treatment of heart failure.
Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiomegaly; Cricetinae | 1999 |
Effect of long-term therapy with fasidotril, a mixed inhibitor of neprilysin and angiotensin-converting enzyme (ACE), on survival of rats after myocardial infarction.
Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Chi-Square Distribution; | 1999 |
Learning from the recently completed oral glycoprotein IIb/IIIa receptor antagonist trials.
Topics: Alanine; Angina, Unstable; Benzamidines; Humans; Myocardial Infarction; Platelet Aggregation Inhibit | 2000 |
Heart failure augments the cardiovascular and renal effects of neutral endopeptidase inhibition in rats.
Topics: Alanine; Animals; Blood Pressure; Body Weight; Central Venous Pressure; Heart Failure; Heart Rate; H | 1991 |
[Mechanisms of ammonia binding in the heart muscle].
Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Glutamine; In Vitr | 1985 |
Altered plasma concentrations of glutamate, alanine and citrate in the early phase of acute myocardial infarction in man.
Topics: Aged; Alanine; Blood Glucose; Citrates; Citric Acid; Digoxin; Fatty Acids, Nonesterified; Glutamates | 1986 |
Is alanine release an early marker of acute myocardial infarction?
Topics: Alanine; Female; Humans; Middle Aged; Myocardial Infarction; Myocardium; Necrosis | 1987 |
Computer simulation and optimization, as exemplified by the enzyme-coupled aminotransferase (transaminase) assays.
Topics: Alanine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspartic Acid; Computers; Evalu | 1974 |
Myocardial ammonia metabolism in patients with heart disease as revealed by coronary sinus catheterization study.
Topics: Adult; Alanine; Ammonia; Cardiac Catheterization; Cineangiography; Coronary Angiography; Coronary Di | 1973 |
[Levels of free amino acids in the blood and heart muscle in the human at various periods of myocardial infarct (clinical anatomical parallels)].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Erythrocytes; Glutamates; Glycine; Hi | 1968 |
[Increased transaminase activity in acute hepatitis, myocardial infarct and other diseases].
Topics: Alanine; Aspartate Aminotransferases; Hepatitis A; Humans; Myocardial Infarction; Pancreatitis | 1966 |