alanine has been researched along with Muscular Dystrophy in 8 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Autosomal dominant oculopharyngeal muscular dystrophy (OPMD) is characterized pathologically by intranuclear inclusions in skeletal muscles and is caused by the expansion of a 10-alanine stretch to 12-17 alanines in the intranuclear poly(A)-binding protein 2 (PABP2)." | 3.71 | Mammalian, yeast, bacterial, and chemical chaperones reduce aggregate formation and death in a cell model of oculopharyngeal muscular dystrophy. ( Bao, YP; Cook, LJ; O'Donovan, D; Rubinsztein, DC; Uyama, E, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Castagnaro, S | 1 |
| Pellegrini, C | 1 |
| Pellegrini, M | 1 |
| Chrisam, M | 1 |
| Sabatelli, P | 1 |
| Toni, S | 1 |
| Grumati, P | 1 |
| Ripamonti, C | 1 |
| Pratelli, L | 1 |
| Maraldi, NM | 1 |
| Cocchi, D | 1 |
| Righi, V | 1 |
| Faldini, C | 1 |
| Sandri, M | 1 |
| Bonaldo, P | 1 |
| Merlini, L | 1 |
| Kraya, T | 1 |
| Kress, W | 1 |
| Stoevesant, D | 1 |
| Deschauer, M | 1 |
| Zierz, S | 1 |
| Tagawa, K | 1 |
| Ogawa, M | 1 |
| Kawabe, K | 1 |
| Yamanaka, G | 1 |
| Matsumura, T | 1 |
| Goto, K | 1 |
| Nonaka, I | 1 |
| Nishino, I | 1 |
| Hayashi, YK | 1 |
| Elia, M | 1 |
| Ilic, V | 1 |
| Bacon, S | 1 |
| Williamson, DH | 1 |
| Smith, R | 1 |
| Bao, YP | 1 |
| Cook, LJ | 1 |
| O'Donovan, D | 1 |
| Uyama, E | 1 |
| Rubinsztein, DC | 1 |
| Haymond, MW | 1 |
| Strobel, KE | 1 |
| DeVivo, DC | 1 |
| Gusev, EI | 1 |
| Maskaleris, ML | 1 |
| Gross, S | 1 |
| Milhorat, AT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Low Protein Diet to Correct Defective Autophagy in Patients With Collagen VI Related Myopathies[NCT01438788] | Phase 2 | 8 participants (Actual) | Interventional | 2011-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for alanine and Muscular Dystrophy
| Article | Year |
|---|---|
Autophagy activation in COL6 myopathic patients by a low-protein-diet pilot trial.
Topics: Adult; Alanine; Autophagy; Biomarkers; Biopsy; Body Composition; Collagen Type VI; Contracture; Diet | 2016 |
7 other studies available for alanine and Muscular Dystrophy
| Article | Year |
|---|---|
[Myofibrillary myopathy due to the ZASP mutation Ala147Thr : two cases with exclusively distal leg involvement].
Topics: Adaptor Proteins, Signal Transducing; Aged; Alanine; Biopsy; Distal Myopathies; DNA Mutational Analy | 2013 |
Protein and gene analyses of dysferlinopathy in a large group of Japanese muscular dystrophy patients.
Topics: Age of Onset; Alanine; Blotting, Western; Calpain; Cysteine; Cytoskeletal Proteins; DNA Mutational A | 2003 |
Relationship between the basal blood alanine concentration and the removal of an alanine load in various clinical states in man.
Topics: Adolescent; Adult; Aged; Alanine; Basal Metabolism; Blood Glucose; Diabetes Mellitus; Female; Half-L | 1980 |
Mammalian, yeast, bacterial, and chemical chaperones reduce aggregate formation and death in a cell model of oculopharyngeal muscular dystrophy.
Topics: Alanine; Animals; Blotting, Western; Chaperonin 60; COS Cells; DNA-Binding Proteins; Green Fluoresce | 2002 |
Muscle wasting and carbohydrate homeostasis in Duchenne muscular dystrophy.
Topics: Adolescent; Alanine; Carbohydrate Metabolism; Child; Child, Preschool; Fasting; Glucose; Glucose Tol | 1978 |
[Hyperaminoaciduria in children suffering from progressive muscular dystrophy].
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Arginine; Aspartic Acid; Child; Child, Pr | 1967 |
Urinary amino acid and peptide excretion patterns in patients with muscular dystrophy (Duchenne). A preliminary study with the autoanalyzer.
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Autoanalysis; Child; Child | 1969 |