alanine has been researched along with Muscular Diseases in 18 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Muscular Diseases: Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "He developed severe sepsis and acute respiratory distress syndrome (ARDS) and received intravenous high dose corticosteroid and tocilizumab to counter SARS-CoV2 associated cytokine surge." | 2.72 | Severe acute myopathy following SARS-CoV-2 infection: a case report and review of recent literature. ( Ahmed, M; Begum, SM; Islam, B; Islam, Z, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (38.89) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Manzano, GS | 1 |
| Woods, JK | 1 |
| Amato, AA | 1 |
| Islam, B | 1 |
| Ahmed, M | 1 |
| Islam, Z | 1 |
| Begum, SM | 1 |
| Castagnaro, S | 1 |
| Pellegrini, C | 1 |
| Pellegrini, M | 1 |
| Chrisam, M | 1 |
| Sabatelli, P | 1 |
| Toni, S | 1 |
| Grumati, P | 1 |
| Ripamonti, C | 1 |
| Pratelli, L | 1 |
| Maraldi, NM | 1 |
| Cocchi, D | 1 |
| Righi, V | 1 |
| Faldini, C | 1 |
| Sandri, M | 1 |
| Bonaldo, P | 1 |
| Merlini, L | 1 |
| Catteruccia, M | 1 |
| Sanna, T | 1 |
| Santorelli, FM | 1 |
| Tessa, A | 1 |
| Di Giacopo, R | 1 |
| Sauchelli, D | 1 |
| Verbo, A | 1 |
| Lo Monaco, M | 1 |
| Servidei, S | 1 |
| Dalakas, MC | 1 |
| Dagvadorj, A | 1 |
| Goudeau, B | 1 |
| Park, KY | 1 |
| Takeda, K | 1 |
| Simon-Casteras, M | 1 |
| Vasconcelos, O | 1 |
| Sambuughin, N | 1 |
| Shatunov, A | 1 |
| Nagle, JW | 1 |
| Sivakumar, K | 1 |
| Vicart, P | 1 |
| Goldfarb, LG | 1 |
| Ørngreen, MC | 2 |
| Ejstrup, R | 2 |
| Vissing, J | 2 |
| Akbari, M | 1 |
| Skjelbred, C | 1 |
| Følling, I | 1 |
| Sagen, J | 1 |
| Krokan, HE | 1 |
| Dunø, M | 1 |
| Christensen, E | 1 |
| Schwartz, M | 1 |
| Sacchetti, M | 1 |
| Horvath, R | 1 |
| Kley, RA | 1 |
| Lochmüller, H | 1 |
| Vorgerd, M | 1 |
| Brown, WR | 1 |
| Pouw, EM | 1 |
| Schols, AM | 1 |
| Deutz, NE | 1 |
| Wouters, EF | 1 |
| Wahren, J | 3 |
| Linderholm, H | 1 |
| Felig, P | 3 |
| McDaniel, HG | 1 |
| Pittman, CS | 1 |
| Oh, SJ | 1 |
| DiMauro, S | 1 |
| Dunn, HG | 1 |
| Dolman, CL | 1 |
| Havel, RJ | 2 |
| Jorfeldt, L | 2 |
| Pernow, B | 2 |
| Saltin, B | 2 |
| Terlow, MJ | 1 |
| Lake, BD | 1 |
| Lloyd, JK | 1 |
| Hackett, TN | 1 |
| Bray, PF | 1 |
| Ziter, FA | 1 |
| Nyhan, WL | 1 |
| Creer, KM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Low Protein Diet to Correct Defective Autophagy in Patients With Collagen VI Related Myopathies[NCT01438788] | Phase 2 | 8 participants (Actual) | Interventional | 2011-10-31 | Completed | ||
| Fat and Sugar Metabolism During Exercise in Patients With Metabolic Myopathy[NCT02635269] | 60 participants (Actual) | Interventional | 2016-01-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for alanine and Muscular Diseases
| Article | Year |
|---|---|
Severe acute myopathy following SARS-CoV-2 infection: a case report and review of recent literature.
Topics: Adenosine Monophosphate; Adult; Alanine; Antibodies, Monoclonal, Humanized; Anticoagulants; Antivira | 2021 |
2 trials available for alanine and Muscular Diseases
| Article | Year |
|---|---|
Autophagy activation in COL6 myopathic patients by a low-protein-diet pilot trial.
Topics: Adult; Alanine; Autophagy; Biomarkers; Biopsy; Body Composition; Collagen Type VI; Contracture; Diet | 2016 |
Effect of diet on exercise tolerance in carnitine palmitoyltransferase II deficiency.
Topics: Alanine; Blood Glucose; Carnitine O-Palmitoyltransferase; Creatine Kinase; Creatine Kinase, MM Form; | 2003 |
15 other studies available for alanine and Muscular Diseases
| Article | Year |
|---|---|
Covid-19-Associated Myopathy Caused by Type I Interferonopathy.
Topics: Adenosine Monophosphate; Adult; Alanine; COVID-19; Humans; Interferon Type I; Male; Methylprednisolo | 2020 |
Rippling muscle disease and cardiomyopathy associated with a mutation in the CAV3 gene.
Topics: Adult; Alanine; Cardiomyopathies; Caveolin 3; Electrocardiography; Electromyography; Family Health; | 2009 |
Progressive skeletal myopathy, a phenotypic variant of desmin myopathy associated with desmin mutations.
Topics: Alanine; Animals; Carcinoma; Cell Line; Cysteine; Desmin; DNA Mutational Analysis; Female; Fluoresce | 2003 |
A gel electrophoresis method for detection of mitochondrial DNA mutation (3243 tRNA(Leu (UUR))) applied to a Norwegian family with diabetes mellitus and hearing loss.
Topics: Alanine; Diabetes Complications; Diabetes Mellitus; DNA Mutational Analysis; DNA, Mitochondrial; Ele | 2004 |
Fuel utilization in subjects with carnitine palmitoyltransferase 2 gene mutations.
Topics: Adolescent; Adult; Alanine; Blood Glucose; Calorimetry; Carnitine O-Palmitoyltransferase; DNA Mutati | 2005 |
Parkinson syndrome, neuropathy, and myopathy caused by the mutation A8344G (MERRF) in tRNALys.
Topics: Aged; Alanine; Amino Acid Substitution; Glycine; Humans; Male; MERRF Syndrome; Muscle, Skeletal; Mus | 2007 |
Comparative histopathologic evaluation of animal studies: murine studies with L-tryptophan and constitutents.
Topics: Alanine; Animals; Drug Combinations; Mice; Mice, Inbred Strains; Muscle, Skeletal; Muscular Diseases | 1996 |
Plasma and muscle amino acid levels in relation to resting energy expenditure and inflammation in stable chronic obstructive pulmonary disease.
Topics: Acute-Phase Proteins; Acute-Phase Reaction; Adipose Tissue; Aged; Alanine; Amino Acids; Arginine; Ca | 1998 |
Amino acid metabolism in patients with a hereditary myopathy and paroxysmal myoglobinuria.
Topics: Adult; Alanine; Amino Acids; Arm; Energy Metabolism; Female; Hemodynamics; Humans; Lactates; Leg; Ma | 1979 |
Carbohydrate metabolism in hypothyroid myopathy.
Topics: Adolescent; Adult; Alanine; Blood Glucose; Creatine Kinase; Fatty Acids, Nonesterified; Female; Glyc | 1977 |
Necrotizing encephalomyelopathy. Report of a case with relapsing polyneuropathy and hyperalaninemia and with manifestations resembling Friedreich's ataxia.
Topics: Alanine; Ataxia; Blindness; Brain; Brain Diseases; Bronchopneumonia; Cerebellar Ataxia; Child; Child | 1969 |
Amino acid metabolism during exercise in McArdle's syndrome: evidence of altered alanine metabolism.
Topics: Alanine; Amino Acids; Glucosyltransferases; Glycogen Storage Disease; Humans; Muscles; Muscular Dise | 1972 |
Amino acid metabolism in McArdle's syndrome.
Topics: Adult; Alanine; Amino Acids; Glucosyltransferases; Glycogen Storage Disease; Humans; Leg; Male; Musc | 1973 |
Chronic lactic acidosis in association with myopathy.
Topics: Acidosis; Alanine; Child; Chronic Disease; Female; Genes, Dominant; Humans; Lactates; Metabolic Dise | 1973 |
A metabolic myopathy associated with chronic lactic acidemia, growth failure, and nerve deafness.
Topics: Acidosis; Alanine; Child; Chromatography, Paper; Deafness; Electromyography; Female; Growth Disorder | 1973 |