alanine has been researched along with Muscular Atrophy, Spinal in 7 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Muscular Atrophy, Spinal: A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Excerpt | Relevance | Reference |
|---|---|---|
| "All patients with spinal muscular atrophy and congenital myopathy and one patient with Duchenne dystrophy, but none of six healthy subjects, developed hypoglycemia." | 1.32 | Patients with severe muscle wasting are prone to develop hypoglycemia during fasting. ( Hebert, A; Laub, M; Vissing, J; Zacho, M; Ørngreen, MC, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pamphlett, R | 1 |
| Marcuzzo, S | 1 |
| Zucca, I | 1 |
| Mastropietro, A | 1 |
| de Rosbo, NK | 1 |
| Cavalcante, P | 1 |
| Tartari, S | 1 |
| Bonanno, S | 1 |
| Preite, L | 1 |
| Mantegazza, R | 1 |
| Bernasconi, P | 1 |
| LaFevre-Bernt, MA | 1 |
| Ellerby, LM | 1 |
| Ørngreen, MC | 1 |
| Zacho, M | 1 |
| Hebert, A | 1 |
| Laub, M | 1 |
| Vissing, J | 1 |
| Bartholdi, D | 1 |
| Zumsteg, D | 1 |
| Verrips, A | 1 |
| Wevers, RA | 1 |
| Sistermans, E | 1 |
| Hess, K | 1 |
| Jung, HH | 1 |
| Wolstencroft, EC | 1 |
| Mattis, V | 1 |
| Bajer, AA | 1 |
| Young, PJ | 1 |
| Lorson, CL | 1 |
| Bruce, AK | 1 |
| Jacobsen, E | 1 |
| Dossing, H | 1 |
| Kondrup, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacokinetics and Safety of Treatment With Paracetamol in Children and Adults With Spinal Muscular Atrophy and Cerebral Palsy[NCT03648658] | Phase 4 | 48 participants (Anticipated) | Interventional | 2019-02-18 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for alanine and Muscular Atrophy, Spinal
| Article | Year |
|---|---|
Study of 962 patients indicates progressive muscular atrophy is a form of ALS.
Topics: Alanine; Amyotrophic Lateral Sclerosis; Humans; Muscular Atrophy, Spinal; Superoxide Dismutase; Supe | 2010 |
Hind limb muscle atrophy precedes cerebral neuronal degeneration in G93A-SOD1 mouse model of amyotrophic lateral sclerosis: a longitudinal MRI study.
Topics: Alanine; Amyotrophic Lateral Sclerosis; Animals; Brain; Disease Models, Animal; Glycine; Hindlimb; H | 2011 |
Kennedy's disease. Phosphorylation of the polyglutamine-expanded form of androgen receptor regulates its cleavage by caspase-3 and enhances cell death.
Topics: Alanine; Amino Acid Substitution; Base Sequence; Caspase 3; Caspases; Cell Death; Cell Line; DNA Pri | 2003 |
Patients with severe muscle wasting are prone to develop hypoglycemia during fasting.
Topics: Adult; Alanine; Blood Glucose; Body Weight; Fasting; Fatty Acids, Nonesterified; Female; Glycerol; H | 2003 |
Spinal phenotype of cerebrotendinous xanthomatosis--a pitfall in the diagnosis of multiple sclerosis.
Topics: Age of Onset; Alanine; Bile Acids and Salts; Cholestanetriol 26-Monooxygenase; Cholestanol; Choleste | 2004 |
A non-sequence-specific requirement for SMN protein activity: the role of aminoglycosides in inducing elevated SMN protein levels.
Topics: Alanine; Amikacin; Amino Acid Substitution; Aminoglycosides; Anti-Bacterial Agents; Antibodies, Mono | 2005 |
Hypoglycaemia in spinal muscular atrophy.
Topics: Adolescent; Adult; Alanine; Blood Glucose; Child; Fasting; Female; Gluconeogenesis; Glucose; Humans; | 1995 |