Page last updated: 2024-11-08

alanine and Muscle Disorders

alanine has been researched along with Muscle Disorders in 18 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
"He developed severe sepsis and acute respiratory distress syndrome (ARDS) and received intravenous high dose corticosteroid and tocilizumab to counter SARS-CoV2 associated cytokine surge."2.72Severe acute myopathy following SARS-CoV-2 infection: a case report and review of recent literature. ( Ahmed, M; Begum, SM; Islam, B; Islam, Z, 2021)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19907 (38.89)18.7374
1990's2 (11.11)18.2507
2000's6 (33.33)29.6817
2010's1 (5.56)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Manzano, GS1
Woods, JK1
Amato, AA1
Islam, B1
Ahmed, M1
Islam, Z1
Begum, SM1
Castagnaro, S1
Pellegrini, C1
Pellegrini, M1
Chrisam, M1
Sabatelli, P1
Toni, S1
Grumati, P1
Ripamonti, C1
Pratelli, L1
Maraldi, NM1
Cocchi, D1
Righi, V1
Faldini, C1
Sandri, M1
Bonaldo, P1
Merlini, L1
Catteruccia, M1
Sanna, T1
Santorelli, FM1
Tessa, A1
Di Giacopo, R1
Sauchelli, D1
Verbo, A1
Lo Monaco, M1
Servidei, S1
Dalakas, MC1
Dagvadorj, A1
Goudeau, B1
Park, KY1
Takeda, K1
Simon-Casteras, M1
Vasconcelos, O1
Sambuughin, N1
Shatunov, A1
Nagle, JW1
Sivakumar, K1
Vicart, P1
Goldfarb, LG1
Ørngreen, MC2
Ejstrup, R2
Vissing, J2
Akbari, M1
Skjelbred, C1
Følling, I1
Sagen, J1
Krokan, HE1
Dunø, M1
Christensen, E1
Schwartz, M1
Sacchetti, M1
Horvath, R1
Kley, RA1
Lochmüller, H1
Vorgerd, M1
Brown, WR1
Pouw, EM1
Schols, AM1
Deutz, NE1
Wouters, EF1
Wahren, J3
Linderholm, H1
Felig, P3
McDaniel, HG1
Pittman, CS1
Oh, SJ1
DiMauro, S1
Dunn, HG1
Dolman, CL1
Havel, RJ2
Jorfeldt, L2
Pernow, B2
Saltin, B2
Terlow, MJ1
Lake, BD1
Lloyd, JK1
Hackett, TN1
Bray, PF1
Ziter, FA1
Nyhan, WL1
Creer, KM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Low Protein Diet to Correct Defective Autophagy in Patients With Collagen VI Related Myopathies[NCT01438788]Phase 28 participants (Actual)Interventional2011-10-31Completed
Fat and Sugar Metabolism During Exercise in Patients With Metabolic Myopathy[NCT02635269]60 participants (Actual)Interventional2016-01-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for alanine and Muscle Disorders

ArticleYear
Severe acute myopathy following SARS-CoV-2 infection: a case report and review of recent literature.
    Skeletal muscle, 2021, 04-21, Volume: 11, Issue:1

    Topics: Adenosine Monophosphate; Adult; Alanine; Antibodies, Monoclonal, Humanized; Anticoagulants; Antivira

2021

Trials

2 trials available for alanine and Muscle Disorders

ArticleYear
Autophagy activation in COL6 myopathic patients by a low-protein-diet pilot trial.
    Autophagy, 2016, Volume: 12, Issue:12

    Topics: Adult; Alanine; Autophagy; Biomarkers; Biopsy; Body Composition; Collagen Type VI; Contracture; Diet

2016
Effect of diet on exercise tolerance in carnitine palmitoyltransferase II deficiency.
    Neurology, 2003, Aug-26, Volume: 61, Issue:4

    Topics: Alanine; Blood Glucose; Carnitine O-Palmitoyltransferase; Creatine Kinase; Creatine Kinase, MM Form;

2003

Other Studies

15 other studies available for alanine and Muscle Disorders

ArticleYear
Covid-19-Associated Myopathy Caused by Type I Interferonopathy.
    The New England journal of medicine, 2020, 12-10, Volume: 383, Issue:24

    Topics: Adenosine Monophosphate; Adult; Alanine; COVID-19; Humans; Interferon Type I; Male; Methylprednisolo

2020
Rippling muscle disease and cardiomyopathy associated with a mutation in the CAV3 gene.
    Neuromuscular disorders : NMD, 2009, Volume: 19, Issue:11

    Topics: Adult; Alanine; Cardiomyopathies; Caveolin 3; Electrocardiography; Electromyography; Family Health;

2009
Progressive skeletal myopathy, a phenotypic variant of desmin myopathy associated with desmin mutations.
    Neuromuscular disorders : NMD, 2003, Volume: 13, Issue:3

    Topics: Alanine; Animals; Carcinoma; Cell Line; Cysteine; Desmin; DNA Mutational Analysis; Female; Fluoresce

2003
A gel electrophoresis method for detection of mitochondrial DNA mutation (3243 tRNA(Leu (UUR))) applied to a Norwegian family with diabetes mellitus and hearing loss.
    Scandinavian journal of clinical and laboratory investigation, 2004, Volume: 64, Issue:2

    Topics: Alanine; Diabetes Complications; Diabetes Mellitus; DNA Mutational Analysis; DNA, Mitochondrial; Ele

2004
Fuel utilization in subjects with carnitine palmitoyltransferase 2 gene mutations.
    Annals of neurology, 2005, Volume: 57, Issue:1

    Topics: Adolescent; Adult; Alanine; Blood Glucose; Calorimetry; Carnitine O-Palmitoyltransferase; DNA Mutati

2005
Parkinson syndrome, neuropathy, and myopathy caused by the mutation A8344G (MERRF) in tRNALys.
    Neurology, 2007, Jan-02, Volume: 68, Issue:1

    Topics: Aged; Alanine; Amino Acid Substitution; Glycine; Humans; Male; MERRF Syndrome; Muscle, Skeletal; Mus

2007
Comparative histopathologic evaluation of animal studies: murine studies with L-tryptophan and constitutents.
    The Journal of rheumatology. Supplement, 1996, Volume: 46

    Topics: Alanine; Animals; Drug Combinations; Mice; Mice, Inbred Strains; Muscle, Skeletal; Muscular Diseases

1996
Plasma and muscle amino acid levels in relation to resting energy expenditure and inflammation in stable chronic obstructive pulmonary disease.
    American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:3

    Topics: Acute-Phase Proteins; Acute-Phase Reaction; Adipose Tissue; Aged; Alanine; Amino Acids; Arginine; Ca

1998
Amino acid metabolism in patients with a hereditary myopathy and paroxysmal myoglobinuria.
    Acta medica Scandinavica, 1979, Volume: 206, Issue:4

    Topics: Adult; Alanine; Amino Acids; Arm; Energy Metabolism; Female; Hemodynamics; Humans; Lactates; Leg; Ma

1979
Carbohydrate metabolism in hypothyroid myopathy.
    Metabolism: clinical and experimental, 1977, Volume: 26, Issue:8

    Topics: Adolescent; Adult; Alanine; Blood Glucose; Creatine Kinase; Fatty Acids, Nonesterified; Female; Glyc

1977
Necrotizing encephalomyelopathy. Report of a case with relapsing polyneuropathy and hyperalaninemia and with manifestations resembling Friedreich's ataxia.
    Neurology, 1969, Volume: 19, Issue:6

    Topics: Alanine; Ataxia; Blindness; Brain; Brain Diseases; Bronchopneumonia; Cerebellar Ataxia; Child; Child

1969
Amino acid metabolism during exercise in McArdle's syndrome: evidence of altered alanine metabolism.
    The Journal of physiology, 1972, Volume: 227, Issue:2

    Topics: Alanine; Amino Acids; Glucosyltransferases; Glycogen Storage Disease; Humans; Muscles; Muscular Dise

1972
Amino acid metabolism in McArdle's syndrome.
    The New England journal of medicine, 1973, Apr-12, Volume: 288, Issue:15

    Topics: Adult; Alanine; Amino Acids; Glucosyltransferases; Glycogen Storage Disease; Humans; Leg; Male; Musc

1973
Chronic lactic acidosis in association with myopathy.
    Archives of disease in childhood, 1973, Volume: 48, Issue:6

    Topics: Acidosis; Alanine; Child; Chronic Disease; Female; Genes, Dominant; Humans; Lactates; Metabolic Dise

1973
A metabolic myopathy associated with chronic lactic acidemia, growth failure, and nerve deafness.
    The Journal of pediatrics, 1973, Volume: 83, Issue:3

    Topics: Acidosis; Alanine; Child; Chromatography, Paper; Deafness; Electromyography; Female; Growth Disorder

1973