alanine has been researched along with Muscle Contraction in 47 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Five patients with McArdle's disease and five patients with mitochondrial myopathies performed the same incremental maximal exercise test." | 1.28 | Exercise intolerance in patients with McArdle's disease or mitochondrial myopathies. ( Camus, F; Chaussain, M; Defoligny, C; Eymard, B; Fardeau, M, 1992) |
| "Alaproclate failed to inhibit 5-HT-induced contractile response in rat stomach fundus strip preparation." | 1.27 | Alaproclate: further pharmacological evidence for 5-HT uptake inhibition in vivo. ( Pawłowski, L; Przegaliński, E; Rawłów, A, 1983) |
| "Glycine, which plays an inhibitory role, especially in the spinal cord, reacted with 6 per cent decrease, whereas GABA which is also considered as an inhibitory neurotransmitter showed a change of + 11 per cent on the potentiated side as compared to the unpotentiated side." | 1.25 | Neurochemical aspects of post-tetanic potentiation of monosynaptic reflexes in the cat spinal cord. I. Analysis of amino acids at maximum of potentiation. ( Behbehani, AW; Neuhoff, V; Quentin, CD, 1975) |
| " With the exception of gamma-amino butyric acid and L-alanine benzyl ester all analogues which had appreciable activity gave dose-response curves parallel to L-alanine." | 1.25 | Isolation and identification of pharmacologically active amino acids in skin and their structure-activity relationship on the guinea-pig ileum. ( Lewis, GP; McMartin, C; Rosenthal, SR; Yates, C, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (55.32) | 18.7374 |
| 1990's | 7 (14.89) | 18.2507 |
| 2000's | 9 (19.15) | 29.6817 |
| 2010's | 5 (10.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johnson, D | 1 |
| Zhu, L | 1 |
| Landim-Vieira, M | 1 |
| Pinto, JR | 1 |
| Chalovich, JM | 1 |
| Ferraresi, C | 1 |
| Beltrame, T | 1 |
| Fabrizzi, F | 1 |
| do Nascimento, ES | 1 |
| Karsten, M | 1 |
| Francisco, Cde O | 1 |
| Borghi-Silva, A | 1 |
| Catai, AM | 1 |
| Cardoso, DR | 1 |
| Ferreira, AG | 1 |
| Hamblin, MR | 1 |
| Bagnato, VS | 1 |
| Parizotto, NA | 1 |
| Seifi, M | 1 |
| Swinny, JD | 1 |
| Khromov, A | 1 |
| Choudhury, N | 1 |
| Stevenson, AS | 1 |
| Somlyo, AV | 1 |
| Eto, M | 1 |
| Mamidi, R | 1 |
| Gollapudi, SK | 1 |
| Mallampalli, SL | 1 |
| Chandra, M | 1 |
| Lang, SE | 1 |
| Robinson, DA | 1 |
| Wu, HC | 1 |
| Herron, TJ | 1 |
| Wahr, PA | 1 |
| Westfall, MV | 1 |
| Rew, Y | 1 |
| Malkmus, S | 1 |
| Svensson, C | 1 |
| Yaksh, TL | 1 |
| Chung, NN | 1 |
| Schiller, PW | 1 |
| Cassel, JA | 1 |
| DeHaven, RN | 1 |
| Taulane, JP | 1 |
| Goodman, M | 1 |
| Teague, B | 1 |
| Asiedu, S | 1 |
| Moore, PK | 1 |
| DIABLOVA, PE | 1 |
| KITA, T | 1 |
| KAMIYA, H | 1 |
| KIYOTA, C | 1 |
| Gwynne, RM | 1 |
| Bornstein, JC | 1 |
| Kendrick-Jones, J | 1 |
| Perry, SV | 1 |
| Rawłów, A | 1 |
| Pawłowski, L | 1 |
| Przegaliński, E | 1 |
| Franconi, F | 1 |
| Giotti, A | 1 |
| Manzini, S | 2 |
| Martini, F | 1 |
| Stendardi, I | 1 |
| Zilletti, L | 1 |
| Devroede, J | 1 |
| Baguet, F | 1 |
| Clark, KL | 1 |
| Pierre, L | 1 |
| MacLean, DA | 1 |
| Barclay, JK | 1 |
| Graham, TE | 1 |
| Hood, DA | 1 |
| Terjung, RL | 1 |
| Bowman, JW | 1 |
| Friedman, AR | 1 |
| Thompson, DP | 1 |
| Ichhpurani, AK | 1 |
| Kellman, MF | 1 |
| Marks, N | 1 |
| Maule, AG | 1 |
| Geary, TG | 1 |
| Astolfi, M | 1 |
| Patacchini, R | 1 |
| Maggi, M | 1 |
| Korman, VL | 1 |
| Tobacman, LS | 1 |
| Jensen, J | 1 |
| Soto, AM | 1 |
| Conlon, JM | 1 |
| Millar, ID | 1 |
| Robson, L | 1 |
| Choi , JM | 1 |
| Shin , YW | 1 |
| Hong , KW | 1 |
| Li, P | 1 |
| Chen, SR | 1 |
| Asukagawa, H | 1 |
| Sutoh, K | 1 |
| Ishizawa, M | 1 |
| Miyazaki, E | 1 |
| Behbehani, AW | 1 |
| Quentin, CD | 1 |
| Neuhoff, V | 1 |
| DeFuria, RR | 1 |
| Kushmerick, MJ | 1 |
| Khosla, MC | 1 |
| Muñoz-Ramírez, H | 1 |
| Hall, MM | 1 |
| Khairallah, PA | 1 |
| Bumpus, FM | 1 |
| Chaussain, M | 1 |
| Camus, F | 1 |
| Defoligny, C | 1 |
| Eymard, B | 1 |
| Fardeau, M | 1 |
| Richter, EA | 1 |
| Mikines, KJ | 1 |
| Galbo, H | 1 |
| Kiens, B | 1 |
| Nie, ZT | 1 |
| Wallberg-Henriksson, H | 1 |
| Johansson, S | 1 |
| Henriksson, J | 2 |
| Rexroth, W | 1 |
| Isgro, F | 1 |
| Koeth, T | 1 |
| Manzl, G | 1 |
| Weicker, H | 1 |
| Jaspers, SR | 1 |
| Fagan, JM | 1 |
| Tischler, ME | 1 |
| Katz, A | 1 |
| Sahlin, K | 1 |
| Eriksson, LS | 1 |
| Broberg, S | 1 |
| Björkman, O | 1 |
| Wahren, J | 1 |
| Andreatta, RH | 1 |
| Scheraga, HA | 1 |
| Regoli, D | 1 |
| Park, WK | 1 |
| Lewis, GP | 1 |
| McMartin, C | 1 |
| Rosenthal, SR | 1 |
| Yates, C | 1 |
| McDonald, TJ | 1 |
| O'Brien, RD | 1 |
| Dunn, FW | 1 |
| Stewart, JM | 1 |
| Murdock, LL | 1 |
| Polácek, I | 1 |
| Krejcí, I | 1 |
| Nesvadba, H | 1 |
| Rudinger, J | 1 |
| Walter, R | 1 |
| Dubois, BM | 1 |
| Schwartz, IL | 1 |
| Bowen, WJ | 1 |
| Suzuki, K | 1 |
| Abiko, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Photobiomodulation With Infrared Light-emitting Diode (LED) in Different Doses on Strength Capacities and Functional Performance of Handball Players and Healthy Individuals[NCT03860766] | 56 participants (Actual) | Interventional | 2020-07-08 | Completed | |||
| Influence of Power and Wavelength on Photobiomodulation Therapy for Muscle Performance in Healthy Subjects[NCT04809415] | 42 participants (Actual) | Interventional | 2021-05-01 | Completed | |||
| Influence of Photobiomodulation on Anaerobic Capacity Under Normoxia and Hypoxia Conditions in Treadmill Runners[NCT05595564] | 7 participants (Actual) | Interventional | 2021-08-31 | Active, not recruiting | |||
| Effects of Phototherapy by Light-emitting Diode Therapy (LEDT) on Clinical, Biochemical and Biomechanical of Muscle Performance in Athletes[NCT01770977] | 45 participants (Actual) | Interventional | 2012-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for alanine and Muscle Contraction
46 other studies available for alanine and Muscle Contraction
| Article | Year |
|---|---|
Basic residues within the cardiac troponin T C terminus are required for full inhibition of muscle contraction and limit activation by calcium.
Topics: Actin Cytoskeleton; Actins; Adenosine Triphosphatases; Alanine; Animals; Arginine; Calcium; Fluoresc | 2019 |
Immunolocalization of AMPA receptor subunits within the enteric nervous system of the mouse colon and the effect of their activation on spontaneous colonic contractions.
Topics: Alanine; Animals; Colon; Enteric Nervous System; Gastrointestinal Motility; Male; Mice; Mice, Inbred | 2016 |
Phosphorylation-dependent autoinhibition of myosin light chain phosphatase accounts for Ca2+ sensitization force of smooth muscle contraction.
Topics: Alanine; Calcium; Calcium Signaling; Catalytic Domain; Escin; Glutathione Transferase; Humans; Inhib | 2009 |
Alanine or aspartic acid substitutions at serine23/24 of cardiac troponin I decrease thin filament activation, with no effect on crossbridge detachment kinetics.
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Substitution; Animals; Aspartic Acid; Calcium; Cyclic | 2012 |
Myofilament incorporation and contractile function after gene transfer of cardiac troponin I Ser43/45Ala.
Topics: Adenoviridae; Alanine; Amino Acid Substitution; Animals; Blotting, Western; Calcium; Culture Media, | 2013 |
Synthesis and biological activities of cyclic lanthionine enkephalin analogues: delta-opioid receptor selective ligands.
Topics: Alanine; Analgesics; Animals; CHO Cells; Cricetinae; Enkephalins; Escape Reaction; Humans; Ileum; In | 2002 |
The smooth muscle relaxant effect of hydrogen sulphide in vitro: evidence for a physiological role to control intestinal contractility.
Topics: Alanine; Alkynes; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Glycine; Guinea P | 2002 |
[Effect of glutamic acid, asparagine, glycocoll and alanine on the contractile function of the skeletal muscle and on its sensitization to potassium ions].
Topics: Alanine; Asparagine; Glutamates; Glutamic Acid; Glycine; Ions; Muscle Contraction; Muscle, Skeletal; | 1962 |
THE PHASE REVERSAL PHENOMENON OF THE GABA-ACTION ON THE HIND GUT OF THE CRAYFISH CAUSED BY THE CHANGE IN THE IONIC COMPOSITION OF THE EXTERNAL MEDIUM.
Topics: Acetylcholine; Alanine; Aminobutyrates; Animals; Aspartic Acid; Astacoidea; Bromides; Calcium; Crust | 1965 |
Local inhibitory reflexes excited by mucosal application of nutrient amino acids in guinea pig jejunum.
Topics: Action Potentials; Adenosine Triphosphate; Alanine; Amino Acids; Animals; Electric Stimulation; Gast | 2007 |
Protein synthesis and enzyme response to contractile activity in skeletal muscle.
Topics: Alanine; Animals; Anura; Azaguanine; Carbon Isotopes; Creatine Kinase; Dactinomycin; Ethionine; Leuc | 1967 |
Alaproclate: further pharmacological evidence for 5-HT uptake inhibition in vivo.
Topics: Alanine; Animals; Central Nervous System; Male; Muscle Contraction; Rats; Rats, Inbred Strains; Rece | 1983 |
The effect of taurine on high potassium-and noradrenaline-induced contraction in rabbit ear artery.
Topics: Alanine; Animals; Arteries; Drug Interactions; In Vitro Techniques; Male; Muscle Contraction; Muscle | 1982 |
[Arginine, octopine and alanine during the tonic and phasic contraction of the anterior byssus retractor muscle of Mytilus edulis].
Topics: Alanine; Animals; Arginine; Bivalvia; Energy Metabolism; Muscle Contraction; Muscle, Smooth | 1982 |
Characterization of endothelin receptors in rat renal artery in vitro.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alanine; Animals; Dose-Response | 1995 |
Electrical stimulation and amino acid and ammonia metabolism in the canine gastrocnemius muscle.
Topics: Adenine Nucleotides; Alanine; Amino Acids; Amino Acids, Branched-Chain; Amino Acids, Essential; Ammo | 1995 |
Endurance training alters alanine and glutamine release from muscle during contractions.
Topics: Alanine; Animals; Glutamine; Male; Muscle Contraction; Muscles; Physical Conditioning, Animal; Physi | 1994 |
Structure-activity relationships of KNEFIRFamide (AF1), a nematode FMRFamide-related peptide, on Ascaris suum muscle.
Topics: Alanine; Amino Acid Sequence; Animals; Ascaris suum; Dose-Response Relationship, Drug; Molecular Seq | 1996 |
Improved discriminatory properties between human and murine tachykinin NK1 receptors of MEN 10930: a new potent and competitive antagonist.
Topics: Alanine; Animals; Binding, Competitive; Biological Assay; Cell Line; Guinea Pigs; Humans; Ileum; In | 1997 |
Mutations in actin subdomain 3 that impair thin filament regulation by troponin and tropomyosin.
Topics: Actin Cytoskeleton; Actins; Alanine; Animals; Ca(2+) Mg(2+)-ATPase; Calcium; Cattle; Models, Chemica | 1999 |
Structure-activity relationships of trout bradykinin ([Arg(0),Trp(5),Leu(8)]-bradykinin).
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Bradykinin; Bradykinin Receptor | 2000 |
Na+-alanine uptake activates a Cl- conductance in frog renal proximal tubule cells via nonconventional PKC.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Alanine; Algorithms; Anima | 2001 |
Rebamipide prevents periarterial blood-induced vasospasm in the rat femoral artery model.
Topics: Alanine; Animals; Aorta, Thoracic; Enzyme Inhibitors; Femoral Artery; Granulocytes; Intercellular Ad | 2001 |
Molecular basis of Ca(2)+ activation of the mouse cardiac Ca(2)+ release channel (ryanodine receptor).
Topics: Adenosine Triphosphate; Alanine; Animals; Calcium; Electrophysiology; Glutamic Acid; Heart; Ion Chan | 2001 |
The alanine-scanning mutagenesis of Dictyostelium myosin II at the ionic interface with actin.
Topics: Actins; Alanine; Animals; Catalytic Domain; Dictyostelium; Ions; Models, Biological; Muscle Contract | 2002 |
[Stimulating effects of alanine and glycine on guinea-pig taenia coli (author's transl)].
Topics: Action Potentials; Alanine; Animals; Atropine; Calcium; Chlorine; Colon; Dose-Response Relationship, | 1979 |
Neurochemical aspects of post-tetanic potentiation of monosynaptic reflexes in the cat spinal cord. I. Analysis of amino acids at maximum of potentiation.
Topics: Action Potentials; Alanine; Amino Acids; Animals; Aspartic Acid; Cats; Electric Stimulation; Female; | 1975 |
ATP utilization associated with recovery metabolism in anaerobic frog muscle.
Topics: Adenosine Triphosphate; Alanine; Anaerobiosis; Animals; Glycerophosphates; Glycogen; In Vitro Techni | 1977 |
Synthesis of angiotensin II antagonists by incorporating alpha-methylalanine or O-methylthreonine residues in angiotension II analogues.
Topics: Alanine; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; In Vitro Techniques; Muscle Contr | 1977 |
Exercise intolerance in patients with McArdle's disease or mitochondrial myopathies.
Topics: Adult; Alanine; Ammonia; Energy Metabolism; Exercise Test; Exercise Tolerance; Female; Glycogen Stor | 1992 |
Effect of exercise on insulin action in human skeletal muscle.
Topics: Adult; Alanine; Fatty Acids, Nonesterified; Glucose; Glycogen; Glycogen Synthase; Humans; Insulin; L | 1989 |
Effects of adrenaline and prior exercise on the release of alanine, glutamine and glutamate from incubated rat skeletal muscle.
Topics: Alanine; Animals; Epinephrine; Glutamates; Glutamic Acid; Glutamine; Glycogen; Male; Muscle Contract | 1989 |
Influence of peripheral arterial occlusive disease on muscular metabolism. Part 2: Changes in pyruvate, alanine, and urea concentration in femoral blood.
Topics: Alanine; Arterial Occlusive Diseases; Exercise Test; Humans; Ischemia; Leg; Muscle Contraction; Musc | 1989 |
Biochemical response to chronic shortening in unloaded soleus muscles.
Topics: Adenine Nucleotides; Alanine; Animals; Glutamates; Glutamic Acid; Glutamine; Hindlimb; Male; Muscle | 1985 |
Muscle ammonia metabolism during isometric contraction in humans.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Adolescent; Adult; Alanine; Ammonia; AMP Deaminase; Fem | 1986 |
Ammonia metabolism during exercise in man.
Topics: Adult; Alanine; Ammonia; Humans; Lactates; Lactic Acid; Leg; Liver; Male; Muscle Contraction; Muscle | 1985 |
Synthesis of (5-valine,7-N-methylalanine)-angiotensin II, a hypertensive peptide.
Topics: Alanine; Angiotensin II; Animals; Blood Pressure; Depression, Chemical; Guinea Pigs; Ileum; Methods; | 1971 |
The pressor and myotropic effects and the antagonistic properties of several analogues of angiotensin II.
Topics: Acetylcholine; Alanine; Amino Acid Sequence; Amino Acids; Angiotensin II; Animals; Blood Pressure; B | 1972 |
Isolation and identification of pharmacologically active amino acids in skin and their structure-activity relationship on the guinea-pig ileum.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Atropine; Chromatography, Ion Exchange; Esters; Guine | 1972 |
Relative potencies of L-glutamate analogs on excitatory neuromuscular synapses of the grasshopper, Romalea microptera.
Topics: Alanine; Animals; Depression, Chemical; Glutamates; Glutarates; Grasshoppers; In Vitro Techniques; M | 1972 |
Analogs of bradykinin containing -2-thienyl-L-alanine.
Topics: Alanine; Animals; Blood Pressure; Bradykinin; Female; Ileum; Male; Muscle Contraction; Peptides; Rat | 1971 |
Crayfish vas deferens: contractions in response to L-glutamate and gamma-aminobutyrate.
Topics: Acetylcholine; Alanine; Amino Acids; Aminobutyrates; Animals; Astacoidea; Dopamine; Dose-Response Re | 1971 |
Action of (1,6-di-alanine)-oxytocin and (1,6-di-serine)-oxytocin on the rat uterus and mammary gland in vitro.
Topics: Alanine; Animals; Calcium; Female; In Vitro Techniques; Magnesium; Mammary Glands, Animal; Muscle Co | 1970 |
Biological significance of the amino acid residue in position 3 of neurohypophyseal hormones and the effect of magnesium on their uterotonic action.
Topics: Alanine; Amino Acid Sequence; Animals; Female; Magnesium; Muscle Contraction; Muscle, Smooth; Oxytoc | 1968 |
Effects of pH, buffers, carnosine, histidine, and beta-alanine on the shortening of glycerol-treated muscle fibers.
Topics: Adenosine Triphosphate; Alanine; Animals; Bicarbonates; Buffers; Glycerol; Histidine; Hydrogen-Ion C | 1965 |
Synthesis of beta-alanine-containing analogs of bradykinin.
Topics: Alanine; Animals; Bradykinin; Chemistry, Organic; Drug Synergism; Ileum; In Vitro Techniques; Mice; | 1966 |