alanine has been researched along with Multiple Organ Failure in 5 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Multiple Organ Failure: A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In both nonseptic and septic trauma, increasing TPN increased the mean clearance rate of all infused AA." | 5.27 | Increased dependence of leucine in posttraumatic sepsis: leucine/tyrosine clearance ratio as an indicator of hepatic impairment in septic multiple organ failure syndrome. ( Belzberg, H; Coleman, B; Pittiruti, M; Placko, R; Sganga, G; Siegel, JH; Wedel, S; Wiles, CE, 1985) |
| " These predictions along with the organ impairment study results may be used to support decision making regarding the RDV dosage adjustment in these patient subgroups." | 1.72 | Whole Body PBPK Modeling of Remdesivir and Its Metabolites to Aid in Estimating Active Metabolite Exposure in the Lung and Liver in Patients With Organ Dysfunction. ( Arya, V; Earp, JC; Fan, J; Grimstein, M; Kitabi, E; Reynolds, KS; Wang, Y; Yang, Y; Zhang, X; Zhu, H, 2022) |
| "One patient experienced a torsade de pointes requiring cardiac resuscitation and one died due to multiple organ failure." | 1.56 | Early experience with remdesivir in SARS-CoV-2 pneumonia. ( Andini, R; Bertolino, L; Corcione, A; Durante-Mangoni, E; Florio, LL; Mele, F; Murino, P; Zampino, R, 2020) |
| "In both nonseptic and septic trauma, increasing TPN increased the mean clearance rate of all infused AA." | 1.27 | Increased dependence of leucine in posttraumatic sepsis: leucine/tyrosine clearance ratio as an indicator of hepatic impairment in septic multiple organ failure syndrome. ( Belzberg, H; Coleman, B; Pittiruti, M; Placko, R; Sganga, G; Siegel, JH; Wedel, S; Wiles, CE, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 4 (80.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, J | 1 |
| Yang, Y | 1 |
| Grimstein, M | 1 |
| Zhang, X | 1 |
| Kitabi, E | 1 |
| Earp, JC | 1 |
| Arya, V | 1 |
| Reynolds, KS | 1 |
| Zhu, H | 1 |
| Wang, Y | 1 |
| Yap, SH | 1 |
| Lee, CS | 1 |
| Furusho, A | 1 |
| Ishii, C | 1 |
| Shaharudin, S | 1 |
| Zulhaimi, NS | 1 |
| Kamarulzaman, A | 1 |
| Kamaruzzaman, SB | 1 |
| Mita, M | 1 |
| Leong, KH | 1 |
| Hamase, K | 1 |
| Rajasuriar, R | 1 |
| Durante-Mangoni, E | 1 |
| Andini, R | 1 |
| Bertolino, L | 1 |
| Mele, F | 1 |
| Florio, LL | 1 |
| Murino, P | 1 |
| Corcione, A | 1 |
| Zampino, R | 1 |
| Lê, MP | 1 |
| Le Hingrat, Q | 1 |
| Jaquet, P | 1 |
| Wicky, PH | 1 |
| Bunel, V | 1 |
| Massias, L | 1 |
| Visseaux, B | 1 |
| Messika, J | 1 |
| Descamps, D | 1 |
| Mal, H | 1 |
| Timsit, JF | 1 |
| Peytavin, G | 1 |
| Pittiruti, M | 1 |
| Siegel, JH | 1 |
| Sganga, G | 1 |
| Coleman, B | 1 |
| Wiles, CE | 1 |
| Belzberg, H | 1 |
| Wedel, S | 1 |
| Placko, R | 1 |
5 other studies available for alanine and Multiple Organ Failure
| Article | Year |
|---|---|
Whole Body PBPK Modeling of Remdesivir and Its Metabolites to Aid in Estimating Active Metabolite Exposure in the Lung and Liver in Patients With Organ Dysfunction.
Topics: Adenosine Monophosphate; Adult; Alanine; Humans; Liver; Lung; Male; Models, Biological; Multiple Org | 2022 |
Plasma d-amino acids are associated with markers of immune activation and organ dysfunction in people with HIV.
Topics: Alanine; Amino Acids; Asparagine; Biomarkers; HIV Infections; Humans; Multiple Organ Failure; Prolin | 2022 |
Early experience with remdesivir in SARS-CoV-2 pneumonia.
Topics: Adenosine Monophosphate; Alanine; Antiviral Agents; Betacoronavirus; Chemical and Drug Induced Liver | 2020 |
Removal of Remdesivir's Metabolite GS-441524 by Hemodialysis in a Double Lung Transplant Recipient with COVID-19.
Topics: Adenosine; Adenosine Monophosphate; Alanine; Antiviral Agents; beta-Cyclodextrins; Betacoronavirus; | 2020 |
Increased dependence of leucine in posttraumatic sepsis: leucine/tyrosine clearance ratio as an indicator of hepatic impairment in septic multiple organ failure syndrome.
Topics: Adolescent; Adult; Alanine; Amino Acids; Amino Acids, Essential; Aspartic Acid; Glutamates; Humans; | 1985 |