alanine has been researched along with Multiple Myeloma in 8 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fatal lactic acidosis has been reported while on the treatment with Nucleoside/nucleotide analogues (NA) for the treatment of hepatitis B, C and HIV." | 5.48 | Tenofovir alafenamide associated fatal lactic acidosis in an autologous hematopoietic stem cell transplant recipient. ( Alsunaid, SR; Ashraf, H; Soubani, AO, 2018) |
| "Fatal lactic acidosis has been reported while on the treatment with Nucleoside/nucleotide analogues (NA) for the treatment of hepatitis B, C and HIV." | 1.48 | Tenofovir alafenamide associated fatal lactic acidosis in an autologous hematopoietic stem cell transplant recipient. ( Alsunaid, SR; Ashraf, H; Soubani, AO, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alsunaid, SR | 1 |
| Ashraf, H | 1 |
| Soubani, AO | 1 |
| Thamm, DH | 1 |
| Vail, DM | 1 |
| Kurzman, ID | 1 |
| Babusis, D | 1 |
| Ray, AS | 1 |
| Sousa-Powers, N | 1 |
| Tumas, DB | 1 |
| STEVE BOCCIARELLI, D | 1 |
| VIOLANTE, A | 1 |
| de Hon, FD | 1 |
| ten Boekel, E | 1 |
| Herrman, J | 1 |
| Clement, C | 1 |
| Ehlers, M | 1 |
| Taga, T | 1 |
| Yasukawa, K | 1 |
| Ohsugi, Y | 1 |
| Kishimoto, T | 1 |
| Rose-John, S | 2 |
| Brakenhoff, JP | 1 |
| Bos, HK | 1 |
| Grötzinger, J | 1 |
| Aarden, LA | 1 |
| Lu, J | 1 |
| Chuntharapai, A | 1 |
| Beck, J | 1 |
| Bass, S | 1 |
| Ow, A | 1 |
| De Vos, AM | 1 |
| Gibbs, V | 1 |
| Kim, KJ | 1 |
| Batuman, V | 1 |
| Sastrasinh, M | 1 |
| Sastrasinh, S | 1 |
| Wu, TT | 1 |
| Kabat, EA | 1 |
1 trial available for alanine and Multiple Myeloma
| Article | Year |
|---|---|
GS-9219/VDC-1101--a prodrug of the acyclic nucleotide PMEG has antitumor activity in spontaneous canine multiple myeloma.
Topics: Alanine; Animals; Antineoplastic Agents; Cell Line, Tumor; Dog Diseases; Dogs; Female; Guanine; Huma | 2014 |
7 other studies available for alanine and Multiple Myeloma
| Article | Year |
|---|---|
Tenofovir alafenamide associated fatal lactic acidosis in an autologous hematopoietic stem cell transplant recipient.
Topics: Acidosis, Lactic; Adenine; Aged; Alanine; Antiviral Agents; Fatal Outcome; Hematopoietic Stem Cell T | 2018 |
[Morphological modifications of the characteristic pathological cells of the Oberling, Guerin and Guerin myeloma in rats treated with bis(beta-chloroethyl)-p-aminophenyl alanine].
Topics: Alanine; Animals; Antineoplastic Agents; Multiple Myeloma; Phenylalanine; Plasma Cells; Rats | 1960 |
Functional distinction of two regions of human interleukin 6 important for signal transduction via gp130.
Topics: Alanine; Antibodies, Monoclonal; Antigens, CD; Gene Library; Genetic Testing; Glutamine; Histidine; | 1995 |
Identification of residues in the putative 5th helical region of human interleukin-6, important for activation of the IL-6 signal transducer, gp130.
Topics: Alanine; Antigens, CD; Cell Division; Cloning, Molecular; Cytokine Receptor gp130; Escherichia coli; | 1996 |
Structure-function study of the extracellular domain of the human IFN-alpha receptor (hIFNAR1) using blocking monoclonal antibodies: the role of domains 1 and 2.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Antibodies, Blocking; Antibodies, Mo | 1998 |
Light chain effects on alanine and glucose uptake by renal brush border membranes.
Topics: Alanine; Animals; Bence Jones Protein; Glucose; Humans; In Vitro Techniques; Kidney; Lactoglobulins; | 1986 |
An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity.
Topics: Alanine; Amino Acid Sequence; Analysis of Variance; Animals; Antibodies; Antibody Specificity; Bence | 1970 |