alanine has been researched along with Mucositis in 6 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Mucositis: An INFLAMMATION of the MUCOSA with burning or tingling sensation. It is characterized by atrophy of the squamous EPITHELIUM, vascular damage, inflammatory infiltration, and ulceration. It usually occurs at the mucous lining of the MOUTH, the GASTROINTESTINAL TRACT or the airway due to chemical irritations, CHEMOTHERAPY, or radiation therapy (RADIOTHERAPY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-Fluorouracil (5-FU)-induced intestinal mucositis is one of the most common morbidities in chemotherapy and involves the reactive oxygen species (ROS) system, apoptosis, and inflammatory cytokines." | 7.81 | Rebamipide attenuates 5-Fluorouracil-induced small intestinal mucositis in a mouse model. ( Han, SH; Kim, HJ; Kim, JH; Lee, JH; Moon, W; Park, J; Park, SJ; Song, GA, 2015) |
| "5-Fluorouracil (5-FU)-induced intestinal mucositis is one of the most common morbidities in chemotherapy and involves the reactive oxygen species (ROS) system, apoptosis, and inflammatory cytokines." | 3.81 | Rebamipide attenuates 5-Fluorouracil-induced small intestinal mucositis in a mouse model. ( Han, SH; Kim, HJ; Kim, JH; Lee, JH; Moon, W; Park, J; Park, SJ; Song, GA, 2015) |
| "Gastrointestinal mucositis is a serious side effect of chemotherapy." | 1.51 | Efficacy of Azatyrosine-Phenylbutyric Hydroxamides, a Histone Deacetylase Inhibitor, on Chemotherapy-Induced Gastrointestinal Mucositis. ( Cheng, YW; Huang, SH; Huang, WK; Hung, CH; Kang, JJ; Liao, PL; Tsai, CH; Wang, HP, 2019) |
| "Oral mucositis is a common adverse effect of chemotherapy that limits the required dose of chemotherapeutic agents." | 1.48 | Rebamipide suppresses 5-fluorouracil-induced cell death via the activation of Akt/mTOR pathway and regulates the expression of Bcl-2 family proteins. ( Asano, RT; Fujimoto, SI; Imano, M; Itoh, T; Matsuda, T; Nishida, S; Satou, T; Takeda, T; Tsubaki, M, 2018) |
| "Chemoradiotherapy for head and neck cancer is associated with a high incidence of severe oral mucositis; an adverse, painful event." | 1.37 | [Investigation of how to prevent mucositis induced by chemoradiotherapy]. ( Hushimi, C; Inoue, T; Kamata, S; Kobayashi, M; Masubuchi, T; Miura, K; Moya, M; Tada, Y; Tajima, H; Tosaka, C, 2011) |
| "Mucositis is one of the most frequent side effects induced by chemotherapy that damages the patients' QOL and response rate." | 1.37 | [The effects of Rebamipide and Polaprezinc mouthwash and uptake on mucositis induced by chemotherapy]. ( Fukuhara, K; Hayaishi, Y; Katsuragi, K; Kodama, S; Morisya, Y; Nakanishi, C; Terakura, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsubaki, M | 1 |
| Takeda, T | 1 |
| Asano, RT | 1 |
| Matsuda, T | 1 |
| Fujimoto, SI | 1 |
| Itoh, T | 1 |
| Imano, M | 1 |
| Satou, T | 1 |
| Nishida, S | 1 |
| Liao, PL | 1 |
| Huang, SH | 1 |
| Hung, CH | 1 |
| Huang, WK | 1 |
| Tsai, CH | 1 |
| Kang, JJ | 1 |
| Wang, HP | 1 |
| Cheng, YW | 1 |
| Kim, HJ | 1 |
| Kim, JH | 1 |
| Moon, W | 1 |
| Park, J | 1 |
| Park, SJ | 1 |
| Song, GA | 1 |
| Han, SH | 1 |
| Lee, JH | 1 |
| Yasuda, T | 1 |
| Chiba, H | 1 |
| Satomi, T | 1 |
| Matsuo, A | 1 |
| Kaneko, T | 1 |
| Miyamatsu, H | 1 |
| Tosaka, C | 1 |
| Tajima, H | 1 |
| Inoue, T | 1 |
| Moya, M | 1 |
| Kobayashi, M | 1 |
| Miura, K | 1 |
| Tada, Y | 1 |
| Masubuchi, T | 1 |
| Hushimi, C | 1 |
| Kamata, S | 1 |
| Fukuhara, K | 1 |
| Terakura, M | 1 |
| Katsuragi, K | 1 |
| Kodama, S | 1 |
| Morisya, Y | 1 |
| Hayaishi, Y | 1 |
| Nakanishi, C | 1 |
1 trial available for alanine and Mucositis
| Article | Year |
|---|---|
[A pilot study of rebamipide-gargle for chemoradiotherapy-induced mucositis in oral cancer patients].
Topics: Aged; Aged, 80 and over; Alanine; Antineoplastic Agents; Combined Modality Therapy; Female; Humans; | 2008 |
5 other studies available for alanine and Mucositis
| Article | Year |
|---|---|
Rebamipide suppresses 5-fluorouracil-induced cell death via the activation of Akt/mTOR pathway and regulates the expression of Bcl-2 family proteins.
Topics: Alanine; Animals; Antimetabolites; Antioxidants; Cell Death; Cell Survival; Fluorouracil; Gene Expre | 2018 |
Efficacy of Azatyrosine-Phenylbutyric Hydroxamides, a Histone Deacetylase Inhibitor, on Chemotherapy-Induced Gastrointestinal Mucositis.
Topics: Alanine; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Disease Models, Animal; Gene Expr | 2019 |
Rebamipide attenuates 5-Fluorouracil-induced small intestinal mucositis in a mouse model.
Topics: Alanine; Animals; Anti-Ulcer Agents; Antimetabolites, Antineoplastic; Apoptosis; Disease Models, Ani | 2015 |
[Investigation of how to prevent mucositis induced by chemoradiotherapy].
Topics: Alanine; Antineoplastic Agents; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; | 2011 |
[The effects of Rebamipide and Polaprezinc mouthwash and uptake on mucositis induced by chemotherapy].
Topics: Aged; Alanine; Antineoplastic Agents; Carnosine; Female; Humans; Male; Middle Aged; Mouthwashes; Muc | 2011 |