alanine has been researched along with Mitochondrial Diseases in 7 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Mitochondrial Diseases: Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hyperornithinemia, hyperammonemia, and homocitrullinuria (HHH) syndrome is caused by mutations in the SLC25A15 (ORNT1) gene encoding the mitochondrial ornithine transporter, but the mechanism of pathogenesis of the encephalopathy, spastic paraparesis and hepatopathy remains undetermined." | 7.72 | Hyperornithinemia, hyperammonemia, and homocitrullinuria syndrome with evidence of mitochondrial dysfunction due to a novel SLC25A15 (ORNT1) gene mutation in a Palestinian family. ( Abu-Libdeh, B; Gutman, A; Kanazawa, N; Korman, SH; Tsujino, S, 2004) |
| "Hyperornithinemia, hyperammonemia, and homocitrullinuria (HHH) syndrome is caused by mutations in the SLC25A15 (ORNT1) gene encoding the mitochondrial ornithine transporter, but the mechanism of pathogenesis of the encephalopathy, spastic paraparesis and hepatopathy remains undetermined." | 3.72 | Hyperornithinemia, hyperammonemia, and homocitrullinuria syndrome with evidence of mitochondrial dysfunction due to a novel SLC25A15 (ORNT1) gene mutation in a Palestinian family. ( Abu-Libdeh, B; Gutman, A; Kanazawa, N; Korman, SH; Tsujino, S, 2004) |
| "Mitochondrial disorders are clinically heterogeneous." | 1.35 | Mitochondrial diseases mimicking neurotransmitter defects. ( Artuch, R; Briones, P; Carrilho, I; Duarte, S; Garcia-Cazorla, A; Garesse, R; Montoya, J; Nascimento, A; Ormazabal, A; Pineda, M; Sala-Castellvi, P; Serrano, M, 2008) |
| "Bezafibrate is a hypolipidemic drug that belongs to the group of peroxisome proliferators because it binds to peroxisome proliferator-activated receptors type alpha (PPARs)." | 1.32 | Bezafibrate induces a mitochondrial derangement in human cell lines: a PPAR-independent mechanism for a peroxisome proliferator. ( Bottoni, P; Castagnola, M; De Sole, P; Giardina, B; Maggiano, N; Martorana, GE; Messana, I; Nocca, G; Scatena, R; Vincenzoni, F, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Majid, H | 1 |
| Jafri, L | 1 |
| Khan, AH | 1 |
| Ali, ZZ | 1 |
| Jamil, A | 1 |
| Yusufzai, N | 1 |
| Fatimah, M | 1 |
| Afroze, B | 1 |
| Garcia-Cazorla, A | 1 |
| Duarte, S | 1 |
| Serrano, M | 1 |
| Nascimento, A | 1 |
| Ormazabal, A | 1 |
| Carrilho, I | 1 |
| Briones, P | 1 |
| Montoya, J | 1 |
| Garesse, R | 1 |
| Sala-Castellvi, P | 1 |
| Pineda, M | 1 |
| Artuch, R | 1 |
| Lee, NC | 1 |
| Dimmock, D | 1 |
| Hwu, WL | 1 |
| Tang, LY | 1 |
| Huang, WC | 1 |
| Chinault, AC | 1 |
| Wong, LJ | 1 |
| Neeve, VC | 1 |
| Samuels, DC | 1 |
| Bindoff, LA | 1 |
| van den Bosch, B | 1 |
| Van Goethem, G | 1 |
| Smeets, H | 1 |
| Lombès, A | 1 |
| Jardel, C | 1 |
| Hirano, M | 1 |
| Dimauro, S | 1 |
| De Vries, M | 2 |
| Smeitink, J | 2 |
| Smits, BW | 1 |
| de Coo, IF | 1 |
| Saft, C | 1 |
| Klopstock, T | 1 |
| Keiling, BC | 1 |
| Czermin, B | 1 |
| Abicht, A | 1 |
| Lochmüller, H | 1 |
| Hudson, G | 1 |
| Gorman, GG | 1 |
| Turnbull, DM | 1 |
| Taylor, RW | 1 |
| Holinski-Feder, E | 1 |
| Chinnery, PF | 1 |
| Horvath, R | 1 |
| Scatena, R | 1 |
| Bottoni, P | 1 |
| Vincenzoni, F | 1 |
| Messana, I | 1 |
| Martorana, GE | 1 |
| Nocca, G | 1 |
| De Sole, P | 1 |
| Maggiano, N | 1 |
| Castagnola, M | 1 |
| Giardina, B | 1 |
| Korman, SH | 1 |
| Kanazawa, N | 1 |
| Abu-Libdeh, B | 1 |
| Gutman, A | 1 |
| Tsujino, S | 1 |
| Morava, E | 1 |
| Hogeveen, M | 1 |
| Ruitenbeek, W | 1 |
| de Boode, WP | 1 |
7 other studies available for alanine and Mitochondrial Diseases
| Article | Year |
|---|---|
Diagnostic dilemma of patients with methylmalonic aciduria: Experience from a tertiary care centre in Pakistan.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Child, Preschool; Citrates; Cross-Sectional Studies; | 2018 |
Mitochondrial diseases mimicking neurotransmitter defects.
Topics: Alanine; Brain; Child, Preschool; Consanguinity; Diagnosis, Differential; Dopamine Agents; Dystonia; | 2008 |
Simultaneous detection of mitochondrial DNA depletion and single-exon deletion in the deoxyguanosine gene using array-based comparative genomic hybridisation.
Topics: Alanine; Base Sequence; Deoxyguanine Nucleotides; DNA Mutational Analysis; DNA, Mitochondrial; Exons | 2009 |
What is influencing the phenotype of the common homozygous polymerase-γ mutation p.Ala467Thr?
Topics: Adolescent; Adult; Age of Onset; Alanine; Child; Cohort Studies; Diffuse Cerebral Sclerosis of Schil | 2012 |
Bezafibrate induces a mitochondrial derangement in human cell lines: a PPAR-independent mechanism for a peroxisome proliferator.
Topics: Acetates; Alanine; Animals; Bezafibrate; Dose-Response Relationship, Drug; Humans; Hypolipidemic Age | 2003 |
Hyperornithinemia, hyperammonemia, and homocitrullinuria syndrome with evidence of mitochondrial dysfunction due to a novel SLC25A15 (ORNT1) gene mutation in a Palestinian family.
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acid Transport Systems, Basic; Arab | 2004 |
Normal serum alanine concentration differentiates transient neonatal lactic acidemia from an inborn error of energy metabolism.
Topics: Alanine; Diagnosis, Differential; DNA, Mitochondrial; Energy Metabolism; Humans; Infant, Newborn; La | 2006 |