alanine has been researched along with Meningioma in 15 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Meningioma: A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "While alanine is a relatively unique marker for meningioma, our results support the hypothesis that the combination of glutamate/creatine ratios and alanine on proton MRS is more specific and reliable for the diagnosis of meningiomas than alanine alone." | 9.12 | Utilization of glutamate/creatine ratios for proton spectroscopic diagnosis of meningiomas. ( Hazany, S; Healy, JF; Hesselink, JR; Imbesi, SG, 2007) |
| "In the present study the mechanism of action of M2-type pyruvate kinase from human meningioma in the simultaneous presence of fructose 1,6 diphosphate and L-alanine was investigated." | 7.68 | Regulation of M2-type pyruvate kinase from human meningioma by allosteric effectors fructose 1,6 diphosphate and L-alanine. ( Altinörs, N; Gündüz, U; Mellati, AA; Yücel, M, 1992) |
| "In gliomas a shift was found in the composition of enzymes, manifested by abnormal inhibition of pyruvate kinase by alanine." | 7.65 | Alanine inhibition of pyruvate kinase in gliomas and meningiomas. A diagnostic tool in surgery for gliomas? ( Staal, GE; van Veelen, CW; Verbiest, H; Vlug, AM, 1977) |
| "While alanine is a relatively unique marker for meningioma, our results support the hypothesis that the combination of glutamate/creatine ratios and alanine on proton MRS is more specific and reliable for the diagnosis of meningiomas than alanine alone." | 5.12 | Utilization of glutamate/creatine ratios for proton spectroscopic diagnosis of meningiomas. ( Hazany, S; Healy, JF; Hesselink, JR; Imbesi, SG, 2007) |
| "The absolute concentrations of total alanine and creatine were decreased in high-grade compared with low-grade meningiomas, as was the ratio of glycine to alanine (all p < 0." | 3.76 | Using ex vivo proton magnetic resonance spectroscopy to reveal associations between biochemical and biological features of meningiomas. ( Coons, SW; Nieman, RA; Pfisterer, WK; Preul, MC; Scheck, AC; Spetzler, RF, 2010) |
| " The spectra from meningiomas, neuroblastomas, and glioblastomas displayed, in addition to similarities-including the presence of signals from leucine, isoleucine, valine, threonine, lactate, acetate, glutamate, choline-containing compounds and glycine-certain distinguishing metabolic features." | 3.69 | Characteristic metabolic profiles revealed by 1H NMR spectroscopy for three types of human brain and nervous system tumours. ( Bhakoo, KK; Florian, CL; Noble, M; Preece, NE; Williams, SR, 1995) |
| "In the present study the mechanism of action of M2-type pyruvate kinase from human meningioma in the simultaneous presence of fructose 1,6 diphosphate and L-alanine was investigated." | 3.68 | Regulation of M2-type pyruvate kinase from human meningioma by allosteric effectors fructose 1,6 diphosphate and L-alanine. ( Altinörs, N; Gündüz, U; Mellati, AA; Yücel, M, 1992) |
| "In gliomas a shift was found in the composition of enzymes, manifested by abnormal inhibition of pyruvate kinase by alanine." | 3.65 | Alanine inhibition of pyruvate kinase in gliomas and meningiomas. A diagnostic tool in surgery for gliomas? ( Staal, GE; van Veelen, CW; Verbiest, H; Vlug, AM, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pfisterer, WK | 1 |
| Nieman, RA | 1 |
| Scheck, AC | 1 |
| Coons, SW | 1 |
| Spetzler, RF | 1 |
| Preul, MC | 2 |
| Righi, V | 1 |
| Tugnoli, V | 1 |
| Mucci, A | 1 |
| Bacci, A | 1 |
| Bonora, S | 1 |
| Schenetti, L | 1 |
| Majós, C | 1 |
| Alonso, J | 1 |
| Aguilera, C | 1 |
| Serrallonga, M | 1 |
| Acebes, JJ | 1 |
| Arús, C | 1 |
| Gili, J | 1 |
| Howe, FA | 1 |
| Barton, SJ | 1 |
| Cudlip, SA | 1 |
| Stubbs, M | 1 |
| Saunders, DE | 1 |
| Murphy, M | 1 |
| Wilkins, P | 1 |
| Opstad, KS | 1 |
| Doyle, VL | 1 |
| McLean, MA | 1 |
| Bell, BA | 1 |
| Griffiths, JR | 1 |
| Bulakbasi, N | 1 |
| Kocaoglu, M | 1 |
| Ors, F | 1 |
| Tayfun, C | 1 |
| Uçöz, T | 1 |
| Bendszus, M | 1 |
| Martin-Schrader, I | 1 |
| Schlake, HP | 1 |
| Solymosi, L | 1 |
| Hazany, S | 1 |
| Hesselink, JR | 1 |
| Healy, JF | 1 |
| Imbesi, SG | 1 |
| Laws, ER | 1 |
| Caramanos, Z | 1 |
| Collins, DL | 1 |
| Villemure, JG | 1 |
| Leblanc, R | 1 |
| Olivier, A | 1 |
| Pokrupa, R | 1 |
| Arnold, DL | 1 |
| Florian, CL | 1 |
| Preece, NE | 1 |
| Bhakoo, KK | 1 |
| Williams, SR | 1 |
| Noble, M | 1 |
| Kasuya, H | 1 |
| Kikuchi, K | 1 |
| Imamura, T | 1 |
| Kawashima, A | 1 |
| Aihara, Y | 1 |
| Ochiai, T | 1 |
| Yamaguchi, K | 1 |
| Fukamachi, K | 1 |
| Hori, T | 1 |
| Shiseki, M | 1 |
| Tozuka, K | 1 |
| van Veelen, CW | 2 |
| Staal, GE | 2 |
| Verbiest, H | 2 |
| Vlug, AM | 2 |
| Rijksen, G | 1 |
| Mellati, AA | 1 |
| Yücel, M | 1 |
| Altinörs, N | 1 |
| Gündüz, U | 1 |
| Peeling, J | 1 |
| Sutherland, G | 1 |
1 trial available for alanine and Meningioma
| Article | Year |
|---|---|
Utilization of glutamate/creatine ratios for proton spectroscopic diagnosis of meningiomas.
Topics: Adult; Aged; Alanine; Biomarkers; Brain; Creatine; Female; Glutamic Acid; Glutathione; Humans; Magne | 2007 |
14 other studies available for alanine and Meningioma
| Article | Year |
|---|---|
Using ex vivo proton magnetic resonance spectroscopy to reveal associations between biochemical and biological features of meningiomas.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Biomarkers, Tumor; Choline; Creatine; Diagnosis, Differenti | 2010 |
MRS study of meningeal hemangiopericytoma and edema: a comparison with meningothelial meningioma.
Topics: 3-Hydroxybutyric Acid; Alanine; Aspartic Acid; Brain Edema; Choline; Creatine; Glutamic Acid; Glutat | 2012 |
Adult primitive neuroectodermal tumor: proton MR spectroscopic findings with possible application for differential diagnosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Astrocytoma; Brain; Brain Neoplasms; Diagnosis, | 2002 |
Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy.
Topics: Alanine; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Glioblastoma; Humans; Inosi | 2003 |
Combination of single-voxel proton MR spectroscopy and apparent diffusion coefficient calculation in the evaluation of common brain tumors.
Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creat | 2003 |
Embolisation of intracranial meningiomas without subsequent surgery.
Topics: Adolescent; Adult; Aged; Alanine; Angiography; Child; Choline; Creatine; Embolization, Therapeutic; | 2003 |
Imaging brain tumors -- beyond three dimensions.
Topics: Aged; Alanine; Brain Neoplasms; Choline; Female; Glioblastoma; Humans; Lactates; Lactic Acid; Magnet | 1996 |
Accurate, noninvasive diagnosis of human brain tumors by using proton magnetic resonance spectroscopy.
Topics: Adult; Alanine; Aspartic Acid; Astrocytoma; Biomarkers; Brain; Brain Neoplasms; Choline; Creatine; D | 1996 |
Characteristic metabolic profiles revealed by 1H NMR spectroscopy for three types of human brain and nervous system tumours.
Topics: Alanine; Amino Acids; Brain Neoplasms; Choline; Chromatography, High Pressure Liquid; Creatine; Glio | 1995 |
[Two cases of methicillin-resistant Staphylococcus aureus (MRSA) sepsis following craniotomy].
Topics: Adult; Aged; Alanine; Aminoglycosides; Ampicillin; Anti-Bacterial Agents; Craniotomy; Dibekacin; Dru | 2000 |
Alanine inhibition of pyruvate kinase in gliomas and meningiomas. A diagnostic tool in surgery for gliomas?
Topics: Alanine; Brain Neoplasms; Glioma; Humans; Isoenzymes; Meningioma; Pyruvate Kinase | 1977 |
Isozymes of pyruvate kinase from human brain, meningiomas, and malignant gliomas.
Topics: Alanine; Brain; Brain Neoplasms; Fetus; Glioblastoma; Glioma; Humans; Infant, Newborn; Isoenzymes; K | 1978 |
Regulation of M2-type pyruvate kinase from human meningioma by allosteric effectors fructose 1,6 diphosphate and L-alanine.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Allosteric Regulation; Fructosediphosphates; | 1992 |
High-resolution 1H NMR spectroscopy studies of extracts of human cerebral neoplasms.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Amino Acids; Astrocytoma; Brain; Brain Neoplasm | 1992 |