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alanine and Meningeal Neoplasms

alanine has been researched along with Meningeal Neoplasms in 11 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Meningeal Neoplasms: Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord.

Research Excerpts

ExcerptRelevanceReference
"While alanine is a relatively unique marker for meningioma, our results support the hypothesis that the combination of glutamate/creatine ratios and alanine on proton MRS is more specific and reliable for the diagnosis of meningiomas than alanine alone."9.12Utilization of glutamate/creatine ratios for proton spectroscopic diagnosis of meningiomas. ( Hazany, S; Healy, JF; Hesselink, JR; Imbesi, SG, 2007)
"In the present study the mechanism of action of M2-type pyruvate kinase from human meningioma in the simultaneous presence of fructose 1,6 diphosphate and L-alanine was investigated."7.68Regulation of M2-type pyruvate kinase from human meningioma by allosteric effectors fructose 1,6 diphosphate and L-alanine. ( Altinörs, N; Gündüz, U; Mellati, AA; Yücel, M, 1992)
"While alanine is a relatively unique marker for meningioma, our results support the hypothesis that the combination of glutamate/creatine ratios and alanine on proton MRS is more specific and reliable for the diagnosis of meningiomas than alanine alone."5.12Utilization of glutamate/creatine ratios for proton spectroscopic diagnosis of meningiomas. ( Hazany, S; Healy, JF; Hesselink, JR; Imbesi, SG, 2007)
"The absolute concentrations of total alanine and creatine were decreased in high-grade compared with low-grade meningiomas, as was the ratio of glycine to alanine (all p < 0."3.76Using ex vivo proton magnetic resonance spectroscopy to reveal associations between biochemical and biological features of meningiomas. ( Coons, SW; Nieman, RA; Pfisterer, WK; Preul, MC; Scheck, AC; Spetzler, RF, 2010)
"In the present study the mechanism of action of M2-type pyruvate kinase from human meningioma in the simultaneous presence of fructose 1,6 diphosphate and L-alanine was investigated."3.68Regulation of M2-type pyruvate kinase from human meningioma by allosteric effectors fructose 1,6 diphosphate and L-alanine. ( Altinörs, N; Gündüz, U; Mellati, AA; Yücel, M, 1992)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's3 (27.27)18.2507
2000's5 (45.45)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pfisterer, WK1
Nieman, RA1
Scheck, AC1
Coons, SW1
Spetzler, RF1
Preul, MC2
Righi, V1
Tugnoli, V1
Mucci, A1
Bacci, A1
Bonora, S1
Schenetti, L1
Majós, C1
Alonso, J1
Aguilera, C1
Serrallonga, M1
Acebes, JJ1
Arús, C1
Gili, J1
Howe, FA1
Barton, SJ1
Cudlip, SA1
Stubbs, M1
Saunders, DE1
Murphy, M1
Wilkins, P1
Opstad, KS1
Doyle, VL1
McLean, MA1
Bell, BA1
Griffiths, JR1
Bulakbasi, N1
Kocaoglu, M1
Ors, F1
Tayfun, C1
Uçöz, T1
Hazany, S1
Hesselink, JR1
Healy, JF1
Imbesi, SG1
Laws, ER1
Caramanos, Z1
Collins, DL1
Villemure, JG1
Leblanc, R1
Olivier, A1
Pokrupa, R1
Arnold, DL1
Kasuya, H1
Kikuchi, K1
Imamura, T1
Kawashima, A1
Aihara, Y1
Ochiai, T1
Yamaguchi, K1
Fukamachi, K1
Hori, T1
Shiseki, M1
Tozuka, K1
van Veelen, CW1
Verbiest, H1
Vlug, AM1
Rijksen, G1
Staal, GE1
Mellati, AA1
Yücel, M1
Altinörs, N1
Gündüz, U1

Trials

1 trial available for alanine and Meningeal Neoplasms

ArticleYear
Utilization of glutamate/creatine ratios for proton spectroscopic diagnosis of meningiomas.
    Neuroradiology, 2007, Volume: 49, Issue:2

    Topics: Adult; Aged; Alanine; Biomarkers; Brain; Creatine; Female; Glutamic Acid; Glutathione; Humans; Magne

2007

Other Studies

10 other studies available for alanine and Meningeal Neoplasms

ArticleYear
Using ex vivo proton magnetic resonance spectroscopy to reveal associations between biochemical and biological features of meningiomas.
    Neurosurgical focus, 2010, Volume: 28, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Biomarkers, Tumor; Choline; Creatine; Diagnosis, Differenti

2010
MRS study of meningeal hemangiopericytoma and edema: a comparison with meningothelial meningioma.
    Oncology reports, 2012, Volume: 28, Issue:4

    Topics: 3-Hydroxybutyric Acid; Alanine; Aspartic Acid; Brain Edema; Choline; Creatine; Glutamic Acid; Glutat

2012
Adult primitive neuroectodermal tumor: proton MR spectroscopic findings with possible application for differential diagnosis.
    Radiology, 2002, Volume: 225, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Astrocytoma; Brain; Brain Neoplasms; Diagnosis,

2002
Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy.
    Magnetic resonance in medicine, 2003, Volume: 49, Issue:2

    Topics: Alanine; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Glioblastoma; Humans; Inosi

2003
Combination of single-voxel proton MR spectroscopy and apparent diffusion coefficient calculation in the evaluation of common brain tumors.
    AJNR. American journal of neuroradiology, 2003, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creat

2003
Imaging brain tumors -- beyond three dimensions.
    Nature medicine, 1996, Volume: 2, Issue:3

    Topics: Aged; Alanine; Brain Neoplasms; Choline; Female; Glioblastoma; Humans; Lactates; Lactic Acid; Magnet

1996
Accurate, noninvasive diagnosis of human brain tumors by using proton magnetic resonance spectroscopy.
    Nature medicine, 1996, Volume: 2, Issue:3

    Topics: Adult; Alanine; Aspartic Acid; Astrocytoma; Biomarkers; Brain; Brain Neoplasms; Choline; Creatine; D

1996
[Two cases of methicillin-resistant Staphylococcus aureus (MRSA) sepsis following craniotomy].
    No shinkei geka. Neurological surgery, 2000, Volume: 28, Issue:5

    Topics: Adult; Aged; Alanine; Aminoglycosides; Ampicillin; Anti-Bacterial Agents; Craniotomy; Dibekacin; Dru

2000
Isozymes of pyruvate kinase from human brain, meningiomas, and malignant gliomas.
    Cancer research, 1978, Volume: 38, Issue:12

    Topics: Alanine; Brain; Brain Neoplasms; Fetus; Glioblastoma; Glioma; Humans; Infant, Newborn; Isoenzymes; K

1978
Regulation of M2-type pyruvate kinase from human meningioma by allosteric effectors fructose 1,6 diphosphate and L-alanine.
    Cancer biochemistry biophysics, 1992, Volume: 13, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Allosteric Regulation; Fructosediphosphates;

1992