alanine has been researched along with MEA 2b in 2 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Most cases of multiple endocrine neoplasia type 2B (MEN-2B) are attributable to a germline methionine to threonine mutation at codon 918 (M918T) of the RET proto-oncogene; very few cases of a germline alanine to phenylalanine mutation at codon 883 (A883F) are reported without a clear description of the clinical course." | 1.37 | Multiple endocrine neoplasia type 2B with a RET proto-oncogene A883F mutation displays a more indolent form of medullary thyroid carcinoma compared with a RET M918T mutation. ( Cote, G; Grubbs, EG; Habra, MA; Hu, MI; Jasim, S; Jimenez, C; Rich, TA; Waguespack, SG; Ying, AK, 2011) |
| "Therefore, early detection of MEN 2B in order to prevent potentially lethal MTC is important." | 1.30 | Germline dinucleotide mutation in codon 883 of the RET proto-oncogene in multiple endocrine neoplasia type 2B without codon 918 mutation. ( Andrew, SD; Dahia, PL; Eng, C; Frilling, A; Gimm, O; Marsh, DJ; Mulligan, LM; Robinson, BG; Zajac, JD, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jasim, S | 1 |
| Ying, AK | 1 |
| Waguespack, SG | 1 |
| Rich, TA | 1 |
| Grubbs, EG | 1 |
| Jimenez, C | 1 |
| Hu, MI | 1 |
| Cote, G | 1 |
| Habra, MA | 1 |
| Gimm, O | 1 |
| Marsh, DJ | 1 |
| Andrew, SD | 1 |
| Frilling, A | 1 |
| Dahia, PL | 1 |
| Mulligan, LM | 1 |
| Zajac, JD | 1 |
| Robinson, BG | 1 |
| Eng, C | 1 |
2 other studies available for alanine and MEA 2b
| Article | Year |
|---|---|
Multiple endocrine neoplasia type 2B with a RET proto-oncogene A883F mutation displays a more indolent form of medullary thyroid carcinoma compared with a RET M918T mutation.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Alanine; Carcinoma, Neuroendocrine; Female; Germ-Line | 2011 |
Germline dinucleotide mutation in codon 883 of the RET proto-oncogene in multiple endocrine neoplasia type 2B without codon 918 mutation.
Topics: Alanine; Codon; Drosophila Proteins; Exons; Germ-Line Mutation; Humans; Multiple Endocrine Neoplasia | 1997 |