alanine has been researched along with MEA 2a in 2 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "S891A mutation caused medullary thyroid cancer (MTC) in 69." | 1.36 | The clinical spectrum of multiple endocrine neoplasia type 2a caused by the rare intracellular RET mutation S891A. ( Aylwin, S; Beck-Peccoz, P; Diaz-Cano, S; Dralle, H; Fugazzola, L; Izatt, L; Machens, A; McGregor, A; Schulte, KM; Talat, N, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schulte, KM | 1 |
| Machens, A | 1 |
| Fugazzola, L | 1 |
| McGregor, A | 1 |
| Diaz-Cano, S | 1 |
| Izatt, L | 1 |
| Aylwin, S | 1 |
| Talat, N | 1 |
| Beck-Peccoz, P | 1 |
| Dralle, H | 1 |
| Kjaer, S | 1 |
| Kurokawa, K | 1 |
| Perrinjaquet, M | 1 |
| Abrescia, C | 1 |
| Ibáñez, CF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Personalized Cancer Therapy for Patients With Metastatic Medullary Thyroid or Metastatic Colon Cancer[NCT02363647] | 10 participants (Actual) | Interventional | 2015-01-31 | Terminated (stopped due to No Current Funding) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for alanine and MEA 2a
| Article | Year |
|---|---|
The clinical spectrum of multiple endocrine neoplasia type 2a caused by the rare intracellular RET mutation S891A.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Alanine; Amino Acid Substitutio | 2010 |
Self-association of the transmembrane domain of RET underlies oncogenic activation by MEN2A mutations.
Topics: Alanine; Amino Acid Sequence; Animals; Cell Membrane; Cysteine; Dimerization; Disulfides; Drosophila | 2006 |