alanine has been researched along with Long QT Syndrome in 9 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In fact, two of the actually used drugs against SARS-CoV2, such as chloroquine and the combination lopinavir/ritonavir, might determine a QT (the time from the start of the Q wave to the end of the T wave) interval prolongation and they show several interactions with antiarrhythmic drugs and antipsychotic medications, making them prone to an increased risk of developing arrhythmias." | 5.12 | COVID-19 and the burning issue of drug interaction: never forget the ECG. ( Cameli, M; Cameli, P; Franchi, F; Mandoli, GE; Menci, D; Mondillo, S; Sciaccaluga, C; Sisti, N; Valente, S, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 6 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Johnson, AA | 1 |
| Crawford, TR | 1 |
| Trudeau, MC | 1 |
| Pilote, S | 1 |
| Simard, C | 1 |
| Drolet, B | 1 |
| Sciaccaluga, C | 1 |
| Cameli, M | 1 |
| Menci, D | 1 |
| Mandoli, GE | 1 |
| Sisti, N | 1 |
| Cameli, P | 1 |
| Franchi, F | 1 |
| Mondillo, S | 1 |
| Valente, S | 1 |
| Zekarias, A | 1 |
| Watson, S | 1 |
| Vidlin, SH | 1 |
| Grundmark, B | 1 |
| Iwahashi, Y | 1 |
| Toyama, Y | 1 |
| Imai, S | 1 |
| Itoh, H | 1 |
| Osawa, M | 1 |
| Inoue, M | 1 |
| Shimada, I | 1 |
| Sendzikaite, S | 1 |
| Heying, R | 1 |
| Milanesi, O | 1 |
| Hanseus, K | 1 |
| Michel-Behnke, I | 1 |
| Kanki, H | 1 |
| Kupershmidt, S | 1 |
| Yang, T | 1 |
| Wells, S | 1 |
| Roden, DM | 1 |
| Bellocq, C | 1 |
| Wilders, R | 1 |
| Schott, JJ | 1 |
| Louérat-Oriou, B | 1 |
| Boisseau, P | 1 |
| Le Marec, H | 1 |
| Escande, D | 1 |
| Baró, I | 1 |
| Smits, JP | 1 |
| Veldkamp, MW | 1 |
| Bezzina, CR | 1 |
| Bhuiyan, ZA | 1 |
| Wedekind, H | 1 |
| Schulze-Bahr, E | 1 |
| Wilde, AA | 1 |
1 review available for alanine and Long QT Syndrome
| Article | Year |
|---|---|
COVID-19 and the burning issue of drug interaction: never forget the ECG.
Topics: Adenosine Monophosphate; Alanine; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Antiviral | 2021 |
8 other studies available for alanine and Long QT Syndrome
| Article | Year |
|---|---|
The N-linker region of hERG1a upregulates hERG1b potassium channels.
Topics: Alanine; Biotin; Ether-A-Go-Go Potassium Channels; Humans; Long QT Syndrome; Mutagenesis; Protein Do | 2022 |
Remdesivir (VEKLURY) for Treating COVID-19: Guinea Pig Ex Vivo and In Vivo Cardiac Electrophysiological Effects.
Topics: Action Potentials; Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Bradycardia; COVID-1 | 2022 |
Sex Differences in Reported Adverse Drug Reactions to COVID-19 Drugs in a Global Database of Individual Case Safety Reports.
Topics: Abdominal Pain; Adenosine Monophosphate; Alanine; Antibodies, Monoclonal, Humanized; Antiviral Agent | 2020 |
Conformational equilibrium shift underlies altered K
Topics: Alanine; Ataxia; Bacterial Proteins; Epilepsy; Humans; Ion Channel Gating; Long QT Syndrome; Magneti | 2020 |
COVID-19 FAQs in paediatric and congenital cardiology: AEPC position paper.
Topics: Adenosine Monophosphate; Alanine; Anti-Arrhythmia Agents; Anticoagulants; Antiviral Agents; Arrhythm | 2021 |
A structural requirement for processing the cardiac K+ channel KCNQ1.
Topics: Alanine; Algorithms; Amino Acid Sequence; Bacterial Proteins; Dimerization; Electric Conductivity; E | 2004 |
A common antitussive drug, clobutinol, precipitates the long QT syndrome 2.
Topics: Alanine; Amino Alcohols; Animals; Antitussive Agents; Arrhythmias, Cardiac; Cation Transport Protein | 2004 |
Substitution of a conserved alanine in the domain IIIS4-S5 linker of the cardiac sodium channel causes long QT syndrome.
Topics: Adolescent; Adult; Alanine; Cell Line; Conserved Sequence; Death, Sudden, Cardiac; Electrophysiology | 2005 |