alanine has been researched along with Liver Diseases in 47 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Liver Diseases: Pathological processes of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 22 patients with chronic pancreatitis and 16 patients with pancreas neoplasms gamma-glutamyltranspeptidase (GGTP) and alanine arylamidase (AAP) in serum were measured and the isoenzymes were determined by gel electrophoresis on Agar." | 7.65 | [Isoenzymes of alanine arylamidase (AAP, EC 3.4.11.2) and gamma-glutamyltranspeptidase (GGTP, EC 2.3.2.2) in chronic pancreatitis and pancreas neoplasm (author's transl)]. ( Bornschein, W, 1975) |
| "Alanine aminotransferase (ALT) is a cost-effective screening test for asymptomatic liver diseases." | 4.12 | Updated upper limits of normal serum alanine aminotrasferase levels for screening metabolic dysfunction-associated fatty liver disease in obese children. ( Chang, PF; Lin, YC; Ni, YH, 2022) |
| "In 22 patients with chronic pancreatitis and 16 patients with pancreas neoplasms gamma-glutamyltranspeptidase (GGTP) and alanine arylamidase (AAP) in serum were measured and the isoenzymes were determined by gel electrophoresis on Agar." | 3.65 | [Isoenzymes of alanine arylamidase (AAP, EC 3.4.11.2) and gamma-glutamyltranspeptidase (GGTP, EC 2.3.2.2) in chronic pancreatitis and pancreas neoplasm (author's transl)]. ( Bornschein, W, 1975) |
| " Recommendations were made based on available data, consideration of pharmacokinetic properties (including variability), the dosing and anticipated treatment duration of each regimen in COVID-19 and known toxicities." | 2.72 | Recommendations for Dosing of Repurposed COVID-19 Medications in Patients with Renal and Hepatic Impairment. ( Back, D; Boyle, A; Burger, D; Davidson, K; El-Sherif, O; Gibbons, S; Khoo, S; Marra, F; Marzolini, C; Siccardi, M; Smolders, EJ; Sommerville, AJ, 2021) |
| "In all, 32 subjects (11 patients with nonalcoholic steatohepatitis [NASH], 15 with simple steatosis [SS], and six healthy controls) were studied." | 1.46 | Hepatic Alanine Differentiates Nonalcoholic Steatohepatitis From Simple Steatosis in Humans and Mice: A Proton MR Spectroscopy Study With Long Echo Time. ( Cho, EY; Choi, KH; Jeong, YY; Jun, CH; Jun, HY; Kim, KJ; Kim, TH; Lee, MS; Lee, YH; Yoon, KH; Yun, KJ, 2017) |
| "Ischemia/reperfusion injury is mediated by various mechanisms." | 1.35 | Fundamental efforts toward the development of a therapeutic cocktail with a manifold ameliorative effect on hepatic ischemia/reperfusion injury. ( Backhaus, J; Büchler, MW; Flechtenmacher, C; Gebhard, MM; Kincius, M; Liang, R; Schemmer, P; Schindler, G; Zorn, M, 2009) |
| " The contributions of the metabolites to the separation of control from dosed liver tissues varied depending on the type of spectral editing method used." | 1.32 | Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues. ( Antti, H; Beckonert, O; Bollard, ME; Ebbels, TM; Holmes, E; Keun, H; Lindon, JC; Nicholson, JK; Tang, H; Wang, Y, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (57.45) | 18.7374 |
| 1990's | 4 (8.51) | 18.2507 |
| 2000's | 4 (8.51) | 29.6817 |
| 2010's | 5 (10.64) | 24.3611 |
| 2020's | 7 (14.89) | 2.80 |
| Authors | Studies |
|---|---|
| Song, IA | 1 |
| Jang, ES | 1 |
| Oh, TK | 1 |
| Lin, YC | 1 |
| Chang, PF | 1 |
| Ni, YH | 1 |
| Hui, B | 1 |
| Shu, Y | 1 |
| Yang, D | 1 |
| Wang, Z | 1 |
| Zhang, L | 1 |
| Lei, N | 1 |
| Yang, Z | 1 |
| Su, TH | 1 |
| Kao, JH | 1 |
| Téllez, L | 1 |
| Martín Mateos, RM | 1 |
| Sabers, AJ | 1 |
| Williams, AL | 1 |
| Farley, TM | 1 |
| Marra, F | 1 |
| Smolders, EJ | 1 |
| El-Sherif, O | 1 |
| Boyle, A | 1 |
| Davidson, K | 1 |
| Sommerville, AJ | 1 |
| Marzolini, C | 1 |
| Siccardi, M | 1 |
| Burger, D | 1 |
| Gibbons, S | 1 |
| Khoo, S | 1 |
| Back, D | 1 |
| Kjaergaard, U | 1 |
| Laustsen, C | 1 |
| Nørlinger, T | 1 |
| Tougaard, RS | 1 |
| Mikkelsen, E | 1 |
| Qi, H | 1 |
| Bertelsen, LB | 1 |
| Jessen, N | 1 |
| Stødkilde-Jørgensen, H | 1 |
| Schmilovitz-Weiss, H | 1 |
| Gingold-Belfer, R | 1 |
| Grossman, A | 1 |
| Issa, N | 1 |
| Boltin, D | 1 |
| Beloosesky, Y | 1 |
| Morag Koren, N | 1 |
| Meyerovitch, J | 1 |
| Weiss, A | 1 |
| Kim, TH | 1 |
| Jun, HY | 1 |
| Kim, KJ | 1 |
| Lee, YH | 1 |
| Lee, MS | 1 |
| Choi, KH | 1 |
| Yun, KJ | 1 |
| Jeong, YY | 1 |
| Jun, CH | 1 |
| Cho, EY | 1 |
| Yoon, KH | 1 |
| Schindler, G | 1 |
| Kincius, M | 1 |
| Liang, R | 1 |
| Backhaus, J | 1 |
| Zorn, M | 1 |
| Flechtenmacher, C | 1 |
| Gebhard, MM | 1 |
| Büchler, MW | 1 |
| Schemmer, P | 1 |
| Wang, X | 1 |
| Zhang, A | 1 |
| Han, Y | 1 |
| Wang, P | 1 |
| Sun, H | 1 |
| Song, G | 1 |
| Dong, T | 1 |
| Yuan, Y | 1 |
| Yuan, X | 1 |
| Zhang, M | 1 |
| Xie, N | 1 |
| Zhang, H | 1 |
| Dong, H | 1 |
| Dong, W | 1 |
| Kurokawa, T | 1 |
| An, J | 1 |
| Tsunekawa, K | 1 |
| Shimomura, Y | 1 |
| Kazama, S | 1 |
| Ishikawa, N | 1 |
| Nonami, T | 1 |
| Sugiyama, S | 1 |
| GIUSTI, G | 1 |
| COLTORTI, M | 1 |
| DI SIMONE, A | 1 |
| SAAD, A | 1 |
| STEIGMANN, F | 1 |
| DUBIN, A | 1 |
| Hutchinson, JH | 1 |
| Jolley, RL | 1 |
| Labby, DH | 1 |
| MONDEN, M | 1 |
| Wang, Y | 1 |
| Bollard, ME | 1 |
| Keun, H | 1 |
| Antti, H | 1 |
| Beckonert, O | 1 |
| Ebbels, TM | 1 |
| Lindon, JC | 1 |
| Holmes, E | 1 |
| Tang, H | 1 |
| Nicholson, JK | 1 |
| Liao, P | 1 |
| Wei, L | 1 |
| Zhang, X | 1 |
| Li, X | 1 |
| Wu, H | 1 |
| Wu, Y | 1 |
| Ni, J | 1 |
| Pei, F | 1 |
| Nishimura, A | 1 |
| Dudley, RE | 1 |
| Klaassen, CD | 2 |
| Roth, E | 1 |
| Funovics, J | 1 |
| Schulz, F | 1 |
| Karner, J | 1 |
| Lee, SM | 1 |
| Kim, KH | 1 |
| Katayama, T | 1 |
| Cheng, CC | 1 |
| Egashira, Y | 1 |
| Ohta, T | 1 |
| Sanada, H | 1 |
| Suzuki, S | 1 |
| Ishii, Y | 1 |
| Asai, S | 1 |
| Kohno, T | 2 |
| Mazaki, T | 1 |
| Takahashi, Y | 1 |
| Ishikawa, K | 1 |
| Bornschein, W | 1 |
| Johnston, DG | 1 |
| Alberti, KG | 1 |
| Ganda, OP | 1 |
| Ruderman, NB | 1 |
| Kossmann, S | 1 |
| Magner-Krezel, Z | 1 |
| Fiaccadori, F | 1 |
| Pedretti, G | 1 |
| Ferrari, C | 1 |
| Pizzaferri, P | 1 |
| Riggio, O | 1 |
| Orlandi, N | 1 |
| Pezzarossa, A | 1 |
| Bell, JD | 1 |
| Brown, JC | 1 |
| Sadler, PJ | 1 |
| Macleod, AF | 1 |
| Sönksen, PH | 1 |
| Hughes, RD | 1 |
| Williams, R | 2 |
| Hazelton, GA | 1 |
| Hjelle, JJ | 1 |
| Usui, H | 1 |
| Ukida, M | 1 |
| Nagashima, H | 1 |
| Peters, JE | 4 |
| Otto, L | 3 |
| Gründig, CA | 2 |
| Nilius, R | 3 |
| Zipprich, B | 1 |
| Eismann, R | 1 |
| Busse, HJ | 1 |
| Thulin, H | 2 |
| Müller, G | 1 |
| Greene, HL | 1 |
| Stifel, FB | 1 |
| Herman, RH | 1 |
| London, JW | 1 |
| Yarrish, R | 1 |
| Dzubow, LD | 1 |
| Garfinkel, D | 1 |
| Schlaeger, R | 2 |
| Burchardt, U | 1 |
| Dingjan, PG | 1 |
| Jongeneel, J | 1 |
| Postma, T | 1 |
| Stroes, JA | 1 |
| Buxton, BH | 1 |
| Stewart, DA | 1 |
| Murray-Lyon, IM | 1 |
| Curzon, G | 1 |
| Vokurková, I | 1 |
| Továrek, J | 1 |
| Kattermann, R | 1 |
| Soliman, L | 1 |
| Abdel Kader, MM | 1 |
| Ata, AA | 1 |
| Abdel Wahab, F | 1 |
| Emara, SH | 1 |
| Ishitoya, Y | 1 |
| Schollmeyer, P | 1 |
| Dold, U | 1 |
| Kunz, W | 1 |
4 reviews available for alanine and Liver Diseases
| Article | Year |
|---|---|
COVID-19 and liver disease: An update.
Topics: Adenosine Monophosphate; Age Factors; Alanine; Antiviral Agents; Betacoronavirus; Bile Ducts; Chemic | 2020 |
Use of remdesivir in the presence of elevated LFTs for the treatment of severe COVID-19 infection.
Topics: Adenosine Monophosphate; Aged, 80 and over; Alanine; Coronavirus Infections; COVID-19; COVID-19 Drug | 2020 |
Recommendations for Dosing of Repurposed COVID-19 Medications in Patients with Renal and Hepatic Impairment.
Topics: Adenosine Monophosphate; Alanine; Antiviral Agents; Clinical Trials as Topic; COVID-19; COVID-19 Dru | 2021 |
Carbohydrate metabolism in liver disease.
Topics: Alanine; Alcoholism; Animals; Blood Glucose; Carbohydrate Metabolism; Disease Models, Animal; Fastin | 1976 |
43 other studies available for alanine and Liver Diseases
| Article | Year |
|---|---|
Validation of Dynamic Aspartate-to-Alanine Aminotransferase Ratio for Predicting Liver Disease Mortality.
Topics: Adult; Alanine; Alanine Transaminase; Aspartate Aminotransferases; Aspartic Acid; Cohort Studies; D- | 2022 |
Updated upper limits of normal serum alanine aminotrasferase levels for screening metabolic dysfunction-associated fatty liver disease in obese children.
Topics: Adolescent; Alanine; Alanine Transaminase; Child; Female; Humans; Liver Diseases; Male; Overweight; | 2022 |
Sinomenine pretreatment alleviates hepatic ischemia/reperfusion injury through activating Nrf-2/HO-1 pathway.
Topics: Alanine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Caspase 3; Glutathione Peroxida | 2022 |
The clinical manifestations and management of COVID-19-related liver injury.
Topics: Adenosine Monophosphate; Alanine; Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-1 | 2020 |
Hyperpolarized [1-
Topics: Alanine; Animals; Blood Glucose; Citric Acid Cycle; Fatty Acids; Female; Glucagon; Insulin; Lactic A | 2018 |
Lowering the upper limit of serum alanine aminotransferase levels may reveal significant liver disease in the elderly.
Topics: Aged; Alanine; Alanine Transaminase; Aspartate Aminotransferases; Fatty Liver; Female; Fibrosis; Ger | 2019 |
Hepatic Alanine Differentiates Nonalcoholic Steatohepatitis From Simple Steatosis in Humans and Mice: A Proton MR Spectroscopy Study With Long Echo Time.
Topics: Adult; Alanine; Animals; Area Under Curve; Biopsy; Case-Control Studies; Fatty Liver; Female; Hepato | 2017 |
Fundamental efforts toward the development of a therapeutic cocktail with a manifold ameliorative effect on hepatic ischemia/reperfusion injury.
Topics: Alanine; Animals; Arginine; Chemotaxis, Leukocyte; Clinical Enzyme Tests; Drug Therapy, Combination; | 2009 |
Urine metabolomics analysis for biomarker discovery and detection of jaundice syndrome in patients with liver disease.
Topics: Adult; Alanine; Aspartic Acid; Biomarkers; Chromatography, High Pressure Liquid; Disease Progression | 2012 |
Effect of L-arginine supplement on liver regeneration after partial hepatectomy in rats.
Topics: Administration, Oral; Alanine; Animals; Arginine; DNA; Glutamine; Hepatectomy; Immunoenzyme Techniqu | 2012 |
[Biochemical aspects of liver necrosis caused by allyl formate; behavior of aspartic- and alanine-ketoglutaric transaminases and phosphoglucomutases in blood and liver tissue].
Topics: Alanine; Alanine Transaminase; Formates; Formic Acid Esters; Intramolecular Transferases; Liver Dise | 1958 |
An enzyme profile in the differential diagnosis of liver disease.
Topics: Alanine; Aspartate Aminotransferases; Diagnosis, Differential; Liver Diseases; Lung Diseases; Oxidor | 1963 |
STUDIES OF RAT LIVER AND KIDNEY ENZYMES. I. RESPONSE TO MASSIVE INTRAGASTRIC DOSES OF CHRONICALLY ADMINISTERED NITROGENOUS SUBSTANCES.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Brain Diseases; Enzymes; Glutamates; Glutamine; Injections; | 1964 |
[A STUDY OF THE FREE AMINO ACIDS IN THE SERUM OF LIVER DISEASES].
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Blood; Carbon Tetrachloride; Chemical and Drug Ind | 1964 |
Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues.
Topics: Alanine; Animals; Chemical and Drug Induced Liver Injury; Choline; Glucose; Glycogen; Hydrazines; Li | 2003 |
Metabolic profiling of serum from gadolinium chloride-treated rats by 1H NMR spectroscopy.
Topics: Alanine; Amino Acids; Animals; Biomarkers; Blood Glucose; Chemical and Drug Induced Liver Injury; Cr | 2007 |
[Studies on hepatic gluconeogenesis in chronic liver diseases; with special references to the effects of L-alanine administration].
Topics: Alanine; Carcinoma, Hepatocellular; Chronic Disease; Gluconeogenesis; Hepatitis, Chronic; Humans; Li | 1984 |
Changes in hepatic glutathione concentration modify cadmium-induced hepatotoxicity.
Topics: Alanine; Animals; Aspartic Acid; Cadmium Poisoning; Chemical and Drug Induced Liver Injury; Cysteine | 1984 |
[Biochemical methods for the determination of a clinical protein catabolism].
Topics: Alanine; Amino Acids; Enteral Nutrition; Gallbladder Diseases; Histidine; Humans; Liver Diseases; Ni | 1980 |
Rebamipide ameliorates hepatic dysfunction induced by ischemia/reperfusion in rats.
Topics: Alanine; Alanine Transaminase; Allopurinol; Animals; Bile; Enzyme Inhibitors; Free Radical Scavenger | 1995 |
Effect of dietary L-glutamine on the hepatotoxic action of D-galactosamine in rats.
Topics: Alanine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver | 1996 |
l-[1-(13)C]Alanine is a useful substance for the evaluation of liver function.
Topics: Alanine; Animals; Breath Tests; Carbon Dioxide; Carbon Isotopes; Hepatectomy; Liver; Liver Diseases; | 2002 |
[Isoenzymes of alanine arylamidase (AAP, EC 3.4.11.2) and gamma-glutamyltranspeptidase (GGTP, EC 2.3.2.2) in chronic pancreatitis and pancreas neoplasm (author's transl)].
Topics: Alanine; Alkaline Phosphatase; Aminopeptidases; Cholestasis; Chronic Disease; Electrophoresis, Agar | 1975 |
Muscle nitrogen metabolism in chronic hepatic insufficiency.
Topics: Adult; Aged; Alanine; Alcoholism; Amino Acids; Ammonia; Brachial Artery; Female; Forearm; Glutamine; | 1976 |
[Biochemical indices of liver function in workers from repair brigades in chemical plants "Organika-Azot" in Jaworz].
Topics: Adult; Alanine; Albumins; alpha-Macroglobulins; Aspartate Aminotransferases; Blood Proteins; Chemica | 1992 |
Insulin and glucagon levels in fulminant hepatic failure in man.
Topics: Adult; Alanine; alpha-Fetoproteins; Amino Acids, Branched-Chain; Blood Glucose; C-Peptide; Female; G | 1991 |
High resolution proton nuclear magnetic resonance studies of human cerebrospinal fluid.
Topics: Acetates; Adolescent; Adult; Aged; Alanine; Child, Preschool; Citrates; Diabetes Mellitus; Female; F | 1987 |
Effects of butylated hydroxyanisole on acetaminophen hepatotoxicity and glucuronidation in vivo.
Topics: Acetaminophen; Alanine; Animals; Anisoles; Aspartate Aminotransferases; Biotransformation; Butylated | 1986 |
Metabolism of branched-chain amino acids in rats with acute hepatic failure: a tracer study using 15N-leucine.
Topics: Alanine; Amino Acids, Branched-Chain; Animals; Chemical and Drug Induced Liver Injury; Galactosamine | 1985 |
[Value of congestive enzymes in liver and biliary tract diseases].
Topics: Alanine; Alkaline Phosphatase; Aminopeptidases; Biliary Tract Diseases; Bone Diseases; Cholestasis; | 1973 |
"Ketotic hypoglycemia" due to hepatic fructose-1,6-diphosphatase deficiency: treatment with folic acid.
Topics: Acidosis; Alanine; Aldehyde-Lyases; Child, Preschool; Fasting; Female; Folic Acid; Fructose; Fructos | 1972 |
[Possibilities for differential diagnosis in hepatobiliary diseases using enzymatic tests].
Topics: Aged; Alanine; Aminopeptidases; Biliary Tract Diseases; Clinical Enzyme Tests; Diagnosis, Differenti | 1972 |
Computer simulation and optimization, as exemplified by the enzyme-coupled aminotransferase (transaminase) assays.
Topics: Alanine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspartic Acid; Computers; Evalu | 1974 |
[Electrophoretic variants of alanine aminopeptidase in serum of patients with hepatobiliary diseases].
Topics: Alanine; Aminopeptidases; Biliary Tract Diseases; Electrophoresis; Gallbladder Diseases; Hepatitis; | 1973 |
[Estimation of serum arylamidase with L-alanine-p-nitroanilide as a substrate. The question of optimal "LAP" tests].
Topics: Alanine; Aminopeptidases; Anilides; Costs and Cost Analysis; Evaluation Studies as Topic; Female; Hu | 1973 |
[Urinary enzyme determinations in hepatobiliary diseases].
Topics: Alanine; Aminopeptidases; Biliary Tract Diseases; Glucuronidase; Hepatitis A; Humans; Liver Cirrhosi | 1973 |
Evaluation of the determination of alanine naphthylamidase isoenzymes by agar and polyacrylamide disc electrophoresis for the diagnosis of pancreatic diseases.
Topics: Agar; Alanine; Alkaline Phosphatase; Aminopeptidases; Clinical Enzyme Tests; Diagnosis, Differential | 1973 |
Plasma amino acids in experimental acute hepatic failure and their relationship to brain tryptophan.
Topics: Acute Disease; Alanine; Amino Acids; Animals; Brain Chemistry; Disease Models, Animal; Glycine; Hepa | 1974 |
[Serum alanine aminopeptidase in the diagnosis of diseases of the liver, bile ducts and pancreas].
Topics: Alanine; Aminopeptidases; Biliary Tract Diseases; Clinical Enzyme Tests; Humans; Liver Diseases; Pan | 1972 |
[Arylamidase and its isoenzymes in diseases of the pancreas and liver].
Topics: Acute Disease; Agar; Alanine; Alkaline Phosphatase; Amides; Aminohydrolases; Anilides; Cholestasis; | 1971 |
Urinary amino acid patterns in simple and complicated bilharziasis.
Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Ascites; Chromatography, Paper; Cystinuria; Hepatomeg | 1969 |
Approach to clinical enzymology.
Topics: Alanine; Animals; Asparagine; Aspartate Aminotransferases; Glucuronates; Glutamates; Humans; Liver D | 1969 |
[Ammonium load in liver patients].
Topics: Alanine; Ammonia; Ammonium Chloride; Citric Acid Cycle; Glutamate Dehydrogenase; Humans; Infusions, | 1965 |