alanine has been researched along with Leukodystrophy, Metachromatic in 2 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Leukodystrophy, Metachromatic: An autosomal recessive metabolic disease caused by a deficiency of CEREBROSIDE-SULFATASE leading to intralysosomal accumulation of cerebroside sulfate (SULFOGLYCOSPHINGOLIPIDS) in the nervous system and other organs. Pathological features include diffuse demyelination, and metachromatically-staining granules in many cell types such as the GLIAL CELLS. There are several allelic and nonallelic forms with a variety of neurological symptoms.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takakusaki, Y | 1 |
| Hisayasu, S | 1 |
| Hirai, Y | 1 |
| Shimada, T | 1 |
| Eto, Y | 1 |
| Ito, T | 1 |
| Kobayashi, H | 1 |
1 review available for alanine and Leukodystrophy, Metachromatic
| Article | Year |
|---|---|
[Multiple sulfatase deficiency].
Topics: Alanine; Aldehydes; Brain; Cysteine; Humans; Kidney; Leukodystrophy, Metachromatic; Sulfatases; Sulf | 1998 |
1 other study available for alanine and Leukodystrophy, Metachromatic
| Article | Year |
|---|---|
Coexpression of formylglycine-generating enzyme is essential for synthesis and secretion of functional arylsulfatase A in a mouse model of metachromatic leukodystrophy.
Topics: Alanine; Animals; Blood-Brain Barrier; Cerebroside-Sulfatase; Chlorocebus aethiops; COS Cells; Gene | 2005 |