alanine has been researched along with Leukodystrophy, Globoid Cell in 1 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Leukodystrophy, Globoid Cell: An autosomal recessive metabolic disorder caused by a deficiency of GALACTOSYLCERAMIDASE leading to intralysosomal accumulation of galactolipids such as GALACTOSYLCERAMIDES and PSYCHOSINE. It is characterized by demyelination associated with large multinucleated globoid cells, predominantly involving the white matter of the central nervous system. The loss of MYELIN disrupts normal conduction of nerve impulses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Krabbe disease (globoid cell leukodystrophy) is an autosomal recessive neurodegenerative disorder that affects both the central and peripheral nervous system due to an enzymatic defect of galactocerebrosidase (GALC)." | 1.30 | Molecular heterogeneity of Krabbe disease. ( Fu, L; Inui, K; Kokubu, C; Muramatsu, T; Nishigaki, T; Okada, S; Tatsumi, N; Tsukamoto, H, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fu, L | 1 |
| Inui, K | 1 |
| Nishigaki, T | 1 |
| Tatsumi, N | 1 |
| Tsukamoto, H | 1 |
| Kokubu, C | 1 |
| Muramatsu, T | 1 |
| Okada, S | 1 |
1 other study available for alanine and Leukodystrophy, Globoid Cell
| Article | Year |
|---|---|
Molecular heterogeneity of Krabbe disease.
Topics: Alanine; Animals; Blotting, Northern; COS Cells; DNA, Complementary; Galactosylceramidase; Gene Dele | 1999 |