Page last updated: 2024-11-08

alanine and Leukemia

alanine has been researched along with Leukemia in 8 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

Research Excerpts

ExcerptRelevanceReference
"L-Alanosine, an antitumor antibiotic was administered by members of the Southwest Oncology Group (SWOG) to 22 patients with resistant acute non-lymphocytic leukemia."7.66The treatment of acute leukemia with continuous infusion L-Alanosine. ( Morrison, FS; Tranum, BL; Weick, JK, 1983)
"L-Alanosine, an antitumor antibiotic was administered by members of the Southwest Oncology Group (SWOG) to 22 patients with resistant acute non-lymphocytic leukemia."3.66The treatment of acute leukemia with continuous infusion L-Alanosine. ( Morrison, FS; Tranum, BL; Weick, JK, 1983)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mansouri-Torshizi, H1
Zareian-Jahromi, S1
Abdi, K1
Saeidifar, M1
Tamaichi, H1
Sato, M1
Porter, AC1
Shimizu, T1
Mizutani, S1
Takagi, M1
KOJIMA, M1
ATCHLEY, WA1
BHAGAVAN, NV1
Nakamura, S1
Kreutz, B1
Tanabe, S1
Suzuki, N1
Kozasa, T1
Weick, JK1
Tranum, BL1
Morrison, FS1
Darker, JG1
Brough, SJ1
Heath, J1
Smart, D1
Rudman, D1
Vogler, WR1
Howard, CH1
Gerron, GG1

Other Studies

8 other studies available for alanine and Leukemia

ArticleYear
Nonionic but water soluble, [Glycine-Pd-Alanine] and [Glycine-Pd-Valine] complexes. Their synthesis, characterization, antitumor activities and rich DNA/HSA interaction studies.
    Journal of biomolecular structure & dynamics, 2019, Volume: 37, Issue:13

    Topics: Alanine; Antineoplastic Agents; Binding Sites; Circular Dichroism; Cisplatin; Coordination Complexes

2019
Ataxia telangiectasia mutated-dependent regulation of topoisomerase II alpha expression and sensitivity to topoisomerase II inhibitor.
    Cancer science, 2013, Volume: 104, Issue:2

    Topics: Alanine; Antigens, Neoplasm; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line,

2013
[TUMOR-FORMING LEUKEMIA (INCLUDING CHLOROMA)].
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1963, Volume: 26

    Topics: Adolescent; Alanine; Antineoplastic Agents; Child; Dexamethasone; Humans; Leukemia; Mechlorethamine;

1963
SALINE-SOLUBLE PREPARATIONS OF DEOXYRIBONUCLEOPROTEINS.
    Archives of biochemistry and biophysics, 1964, Jul-20, Volume: 106

    Topics: Acetates; Alanine; Aminobutyrates; Aminocaproates; Aminocaproic Acid; Animals; Cadmium; Caprylates;

1964
Critical role of lysine 204 in switch I region of Galpha13 for regulation of p115RhoGEF and leukemia-associated RhoGEF.
    Molecular pharmacology, 2004, Volume: 66, Issue:4

    Topics: Alanine; Amino Acid Substitution; Animals; COS Cells; GTP-Binding Protein alpha Subunits, G12-G13; G

2004
The treatment of acute leukemia with continuous infusion L-Alanosine.
    Investigational new drugs, 1983, Volume: 1, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Alanine; Antibiotics, Antineoplastic; Drug Evaluation; Femal

1983
Discovery of potent and selective peptide agonists at the GRP-preferring bombesin receptor (BB2).
    Journal of peptide science : an official publication of the European Peptide Society, 2001, Volume: 7, Issue:11

    Topics: Alanine; Amino Acid Substitution; Animals; Bombesin; Calcium; Cell Line; Gastrin-Releasing Peptide;

2001
Observations on the plasma amino acids of patients with acute leukemia.
    Cancer research, 1971, Volume: 31, Issue:8

    Topics: Acute Disease; Alanine; Amino Acids; Asparaginase; Cytarabine; Glucocorticoids; Glutamine; Histidine

1971