Page last updated: 2024-11-08

alanine and Ischemia

alanine has been researched along with Ischemia in 25 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder characterized by myokymia and attacks of ataxic gait often precipitated by stress."1.38Kv1.1 knock-in ataxic mice exhibit spontaneous myokymic activity exacerbated by fatigue, ischemia and low temperature. ( Botti, FM; Brunetti, O; D'Adamo, MC; Di Giovanni, G; Gibertini, S; Imbrici, P; Mora, M; Muscat, R; Pessia, M; Pettorossi, VE; Valentino, M; Zammit, C, 2012)
"This hypoglycemia is not affected by treatment with adrenaline, glucagon, nicotinadenine dinucleotide (NAD), adenosine triphosphate (ATP) alanine (A), or pyruvate (P), while fructose (F) and dihydroxyacetone (DHA) slightly increase the plasma glucose concentration."1.27Studies on the site of the block in gluconeogenesis causing severe hypoglycemia in intestinal ischemia shock in rats. ( Snijders, PM; Valkenburg, PW; van der Meer, C, 1985)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19907 (28.00)18.7374
1990's9 (36.00)18.2507
2000's5 (20.00)29.6817
2010's4 (16.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sato, PY1
Chuprun, JK1
Grisanti, LA1
Woodall, MC1
Brown, BR1
Roy, R1
Traynham, CJ1
Ibetti, J1
Lucchese, AM1
Yuan, A1
Drosatos, K1
Tilley, DG1
Gao, E1
Koch, WJ1
Mosnier, LO1
Fernández, JA1
Davis, TP1
Zlokovic, BV1
Griffin, JH1
Mango, D1
Barbato, G1
Piccirilli, S1
Panico, MB1
Feligioni, M1
Schepisi, C1
Graziani, M1
Porrini, V1
Benarese, M1
Lanzillotta, A1
Pizzi, M1
Pieraccini, S1
Sironi, M1
Blandini, F1
Nicoletti, F1
Mercuri, NB1
Imbimbo, BP1
Nisticò, R1
Brunetti, O1
Imbrici, P1
Botti, FM1
Pettorossi, VE1
D'Adamo, MC1
Valentino, M1
Zammit, C1
Mora, M1
Gibertini, S1
Di Giovanni, G1
Muscat, R1
Pessia, M1
Kozar, RA1
Schultz, SG1
Hassoun, HT1
Desoignie, R1
Weisbrodt, NW1
Haber, MM1
Moore, FA1
King, N1
Lin, H1
McGivan, JD1
Suleiman, MS1
Huang, Q1
Li, N1
Zhang, W1
Zhu, W1
Li, Q1
Wang, B1
Li, J1
Desgrandchamps, F1
Eugene, M1
Tuchschmid, Y1
Muller, F1
Le Moyec, L1
Teillac, P1
Bedrossian, J1
Idatte, JM1
Le Duc, A1
Muller, A1
Villain, M1
Bonne, C1
Morikawa, S1
Inubushi, T1
Takahashi, K1
Shigemori, S1
Ishii, H1
Patry, J1
Adam, R2
Dimicoli, JL2
Dagher, PC1
Arnault, I1
Bao, YM1
Lemoine, A1
Sebagh, M1
Garcia, JH1
Lossinsky, AS1
Kauffman, FC1
Conger, KA1
McDaniel, HG1
Pittman, CS1
Oh, SJ1
DiMauro, S1
Paller, MS1
Patten, M1
Montañés, I1
Badía, A1
Rengel, MA1
López-Farré, A1
López-Novoa, JM1
Rexroth, W2
Hild, R1
Johnston, JK1
Freeman, DE1
Gillette, D1
Soma, LR1
Weinberg, JM1
Isgro, F1
Koeth, T1
Manzl, G1
Weicker, H1
Martiniak, J1
Chavko, M1
Marsala, J1
van der Meer, C1
Valkenburg, PW1
Snijders, PM1
Folbergrová, J1
Ljunggren, B1
Norberg, K1
Siesjö, BK1
Brosnan, JT1
Krebs, HA1
Williamson, DH1

Reviews

1 review available for alanine and Ischemia

ArticleYear
The effect of amino acids on ischemic and toxic injury to the kidney.
    Seminars in nephrology, 1990, Volume: 10, Issue:5

    Topics: Acute Kidney Injury; Alanine; Amino Acids; Animals; Glutathione; Glycine; Humans; Ischemia; Kidney

1990

Other Studies

24 other studies available for alanine and Ischemia

ArticleYear
Restricting mitochondrial GRK2 post-ischemia confers cardioprotection by reducing myocyte death and maintaining glucose oxidation.
    Science signaling, 2018, 12-11, Volume: 11, Issue:560

    Topics: Alanine; Animals; Apoptosis; G-Protein-Coupled Receptor Kinase 2; Glucose; Heart Failure; Ischemia;

2018
Influence of the 3K3A-activated protein C variant on the plasma clot lysis activity of t-PA and of t-PA on the variant's anticoagulant activity.
    Journal of thrombosis and haemostasis : JTH, 2013, Volume: 11, Issue:11

    Topics: Alanine; Anticoagulants; Blood Coagulation; Dose-Response Relationship, Drug; Genetic Variation; Hum

2013
Electrophysiological and metabolic effects of CHF5074 in the hippocampus: protection against in vitro ischemia.
    Pharmacological research, 2014, Volume: 81

    Topics: Acetates; Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Cells, Cultured;

2014
Kv1.1 knock-in ataxic mice exhibit spontaneous myokymic activity exacerbated by fatigue, ischemia and low temperature.
    Neurobiology of disease, 2012, Volume: 47, Issue:3

    Topics: Alanine; Animals; Ataxia; Calcium; Calcium Signaling; Cold Temperature; Disease Models, Animal; Elec

2012
The type of sodium-coupled solute modulates small bowel mucosal injury, transport function, and ATP after ischemia/reperfusion injury in rats.
    Gastroenterology, 2002, Volume: 123, Issue:3

    Topics: Adenosine Triphosphate; Alanine; Amino Acids; Animals; Biological Transport; Drug Combinations; Gluc

2002
Aspartate transporter expression and activity in hypertrophic rat heart and ischaemia-reperfusion injury.
    The Journal of physiology, 2004, May-01, Volume: 556, Issue:Pt 3

    Topics: Adenosine Triphosphate; Alanine; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Blotting,

2004
Na+-dependent neutral amino acid transporter ASCT2 is downregulated in seriously traumatized human intestinal epithelial cells.
    Journal of pediatric gastroenterology and nutrition, 2008, Volume: 46, Issue:1

    Topics: Alanine; Amino Acid Transport System ASC; Amino Acids; Blotting, Western; Caco-2 Cells; Cell Hypoxia

2008
A cooling jacket to reduce tubular damage during kidney transplantation: evaluation of a prototype in the pig model.
    Transplantation proceedings, 1996, Volume: 28, Issue:1

    Topics: Alanine; Anastomosis, Surgical; Animals; Creatinine; Equipment Design; Humans; Ischemia; Kidney; Kid

1996
The release of amino acids from ischemic retina.
    Experimental eye research, 1997, Volume: 64, Issue:2

    Topics: Alanine; Amino Acids; Animals; Glutamic Acid; Glycine; Ischemia; Male; Ocular Hypertension; Rabbits;

1997
Relationship between gluconeogenesis and phosphoenergetics in rat liver assessed by in vivo 13C and 31P NMR spectroscopy.
    NMR in biomedicine, 1997, Volume: 10, Issue:1

    Topics: Adenosine Triphosphate; Alanine; Animals; Blood Glucose; Carbon Isotopes; Energy Metabolism; Glucone

1997
The effect of dichloroacetate and alanine on the metabolic recovery of perfused mouse liver after cold ischemia.
    NMR in biomedicine, 1999, Volume: 12, Issue:6

    Topics: Adenosine; Alanine; Allopurinol; Animals; Carbon Isotopes; Cold Temperature; Cryopreservation; Dichl

1999
Modeling ischemia in vitro: selective depletion of adenine and guanine nucleotide pools.
    American journal of physiology. Cell physiology, 2000, Volume: 279, Issue:4

    Topics: Adenosine Triphosphate; Alanine; Animals; Antibiotics, Antineoplastic; Antimycin A; Apoptosis; Cell

2000
Combined effects of fasting and alanine on liver function recovery after cold ischemia.
    Transplant international : official journal of the European Society for Organ Transplantation, 2002, Volume: 15, Issue:2-3

    Topics: Alanine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile; Body Weight; Cold Tempera

2002
Neuronal ischemic injury: light microscopy, ultrastructure and biochemistry.
    Acta neuropathologica, 1978, Aug-07, Volume: 43, Issue:1-2

    Topics: Alanine; Animals; Aspartic Acid; Brain; Brain Chemistry; Brain Death; Cats; Cell Survival; Cerebrova

1978
Carbohydrate metabolism in hypothyroid myopathy.
    Metabolism: clinical and experimental, 1977, Volume: 26, Issue:8

    Topics: Adolescent; Adult; Alanine; Blood Glucose; Creatine Kinase; Fatty Acids, Nonesterified; Female; Glyc

1977
Protective effects of glutathione, glycine, or alanine in an in vitro model of renal anoxia.
    Journal of the American Society of Nephrology : JASN, 1992, Volume: 2, Issue:8

    Topics: Alanine; Animals; Buthionine Sulfoximine; Cells, Cultured; Glutathione; Glycine; Hypoxia; Ischemia;

1992
Intermediary metabolism in renal proximal tubules in the recovery phase of experimental renal ischemia in dogs.
    Renal failure, 1991, Volume: 13, Issue:2-3

    Topics: Alanine; Ammonia; Analysis of Variance; Animals; Dogs; Glucose; Glutamates; Glutamic Acid; Glutamine

1991
[Biochemical modifications in stress ischemia of the calf muscles].
    VASA. Supplementum, 1991, Volume: 32

    Topics: Alanine; Ammonia; Energy Metabolism; Humans; Hypoxanthine; Hypoxanthines; Intermittent Claudication;

1991
Effects of superoxide dismutase on injury induced by anoxia and reoxygenation in equine small intestine in vitro.
    American journal of veterinary research, 1991, Volume: 52, Issue:12

    Topics: Alanine; Animals; Culture Techniques; Female; Horse Diseases; Horses; Hypoxia; Intestinal Obstructio

1991
Influence of peripheral arterial occlusive disease on muscular metabolism. Part 2: Changes in pyruvate, alanine, and urea concentration in femoral blood.
    Klinische Wochenschrift, 1989, Jun-15, Volume: 67, Issue:12

    Topics: Alanine; Arterial Occlusive Diseases; Exercise Test; Humans; Ischemia; Leg; Muscle Contraction; Musc

1989
Free amino acids in the spinal cord and ganglia of dogs after ligation of the abdominal aorta.
    Physiologia Bohemoslovaca, 1985, Volume: 34, Issue:1

    Topics: Alanine; Amino Acids; Animals; Aorta, Abdominal; Aspartic Acid; Dogs; Female; Ganglia, Spinal; Gluta

1985
Studies on the site of the block in gluconeogenesis causing severe hypoglycemia in intestinal ischemia shock in rats.
    Circulatory shock, 1985, Volume: 16, Issue:2

    Topics: Adenosine Triphosphate; Alanine; Animals; Epinephrine; Female; Glucagon; Gluconeogenesis; Hypoglycem

1985
Influence of complete ischemia on glycolytic metabolites, citric acid cycle intermediates, and associated amino acids in the rat cerebral cortex.
    Brain research, 1974, Nov-15, Volume: 80, Issue:2

    Topics: Acetone; Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Brain Chemistry; Cerebral Cortex;

1974
Effects of ischaemia on metabolite concentrations in rat liver.
    The Biochemical journal, 1970, Volume: 117, Issue:1

    Topics: Acetoacetates; Adenine Nucleotides; Alanine; Ammonia; Animals; Aspartic Acid; Cycloserine; Freezing;

1970