alanine has been researched along with Invasiveness, Neoplasm in 12 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The median time to reach the maximal plasma concentration of brivanib was 1 h, geometric mean maximal plasma concentration was 6146 ng/ml, mean terminal half-life was 13." | 2.75 | Metabolism, excretion, and pharmacokinetics of oral brivanib in patients with advanced or metastatic solid tumors. ( Fischer, BS; Gan, J; Ganapathi, R; Gong, J; Iyer, R; Masson, E; Mekhail, T; Patricia, D; Pursley, J; Williams, D, 2010) |
| "Although colorectal cancer (CRC) is considered one of the most preventable cancers, no non-invasive, accurate diagnostic tool to screen CRC exists." | 1.51 | Urine-NMR metabolomics for screening of advanced colorectal adenoma and early stage colorectal cancer. ( Kim, ER; Kim, JJ; Kim, YH; Kwon, HN; Nam, H; Park, S, 2019) |
| "We hypothesized that the progression of bladder cancer could be accompanied by changes in cells glycolytic profile." | 1.42 | The progression from a lower to a higher invasive stage of bladder cancer is associated with severe alterations in glucose and pyruvate metabolism. ( Alves, MG; Conde, VR; Nunes, AR; Oliveira, PF; Pereira, JA; Ramalhosa, E; Rocha, CS; Silva, BM, 2015) |
| "In specimens (Borrmann type III) with tubular adenocarcinoma, resonance peaks were observed at 1." | 1.32 | Ex vivo proton MR spectroscopy (1H-MRS) for evaluation of human gastric carcinoma. ( Cha, SS; Cho, JY; Choi, KS; Eun, CK; Kim, J; Lee, J; Lee, SY; Mun, CW; Nam, SH; Shin, WJ; Yang, YI, 2004) |
| "Elastase activities in intact human bladder cancer cell lines, established from three patients, were measured using a fluorogenic substrate highly specific for elastase, under conditions of physiological pH and ionic strength." | 1.28 | Elastase activities of human bladder cancer cell lines derived from high grade invasive tumours. ( Grant, AJ; Raghavan, D; Russell, PJ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, ER | 1 |
| Kwon, HN | 1 |
| Nam, H | 1 |
| Kim, JJ | 1 |
| Park, S | 1 |
| Kim, YH | 1 |
| Conde, VR | 1 |
| Oliveira, PF | 1 |
| Nunes, AR | 1 |
| Rocha, CS | 1 |
| Ramalhosa, E | 1 |
| Pereira, JA | 1 |
| Alves, MG | 1 |
| Silva, BM | 1 |
| Mekhail, T | 1 |
| Masson, E | 1 |
| Fischer, BS | 1 |
| Gong, J | 1 |
| Iyer, R | 1 |
| Gan, J | 1 |
| Pursley, J | 1 |
| Patricia, D | 1 |
| Williams, D | 1 |
| Ganapathi, R | 1 |
| Donini, CF | 1 |
| Di Zazzo, E | 1 |
| Zuchegna, C | 1 |
| Di Domenico, M | 1 |
| D'Inzeo, S | 1 |
| Nicolussi, A | 1 |
| Avvedimento, EV | 1 |
| Coppa, A | 1 |
| Porcellini, A | 1 |
| Kang, DW | 1 |
| Hwang, WC | 1 |
| Park, MH | 1 |
| Ko, GH | 1 |
| Ha, WS | 1 |
| Kim, KS | 1 |
| Lee, YC | 1 |
| Choi, KY | 1 |
| Min, DS | 1 |
| Chan, PK | 1 |
| Lam, CW | 1 |
| Cheung, TH | 1 |
| Li, WW | 1 |
| Lo, KW | 1 |
| Chan, MY | 1 |
| Cheung, JL | 1 |
| Cheng, AF | 1 |
| Masaki, T | 1 |
| Sugiyama, M | 1 |
| Matsuoka, H | 1 |
| Abe, N | 1 |
| Izumisato, Y | 1 |
| Goto, A | 1 |
| Sakamoto, A | 1 |
| Atomi, Y | 1 |
| Mun, CW | 1 |
| Cho, JY | 1 |
| Shin, WJ | 1 |
| Choi, KS | 1 |
| Eun, CK | 1 |
| Cha, SS | 1 |
| Lee, J | 1 |
| Yang, YI | 1 |
| Nam, SH | 1 |
| Kim, J | 1 |
| Lee, SY | 1 |
| Grand, S | 1 |
| Tropres, I | 1 |
| Hoffmann, D | 1 |
| Ziegler, A | 1 |
| Le Bas, JF | 1 |
| Azuma, H | 1 |
| Ehata, S | 1 |
| Miyazaki, H | 1 |
| Watabe, T | 1 |
| Maruyama, O | 1 |
| Imamura, T | 1 |
| Sakamoto, T | 1 |
| Kiyama, S | 1 |
| Kiyama, Y | 1 |
| Ubai, T | 1 |
| Inamoto, T | 1 |
| Takahara, S | 1 |
| Itoh, Y | 1 |
| Otsuki, Y | 1 |
| Katsuoka, Y | 1 |
| Miyazono, K | 1 |
| Horie, S | 1 |
| Starkey, JR | 1 |
| Dai, S | 1 |
| Dratz, EA | 1 |
| Grant, AJ | 1 |
| Russell, PJ | 1 |
| Raghavan, D | 1 |
1 trial available for alanine and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Metabolism, excretion, and pharmacokinetics of oral brivanib in patients with advanced or metastatic solid tumors.
Topics: Administration, Oral; Aged; Alanine; Antineoplastic Agents; Chromatography, High Pressure Liquid; Do | 2010 |
11 other studies available for alanine and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Urine-NMR metabolomics for screening of advanced colorectal adenoma and early stage colorectal cancer.
Topics: Adenoma; Adult; Aged; Aged, 80 and over; Alanine; Aminoisobutyric Acids; Biomarkers, Tumor; Colorect | 2019 |
The progression from a lower to a higher invasive stage of bladder cancer is associated with severe alterations in glucose and pyruvate metabolism.
Topics: Alanine; Alanine Transaminase; Cell Line, Tumor; Disease Progression; Glucose; Glucose Transporter T | 2015 |
The p85α regulatory subunit of PI3K mediates cAMP-PKA and retinoic acid biological effects on MCF7 cell growth and migration.
Topics: Alanine; Animals; Antineoplastic Agents; Aspartic Acid; Breast Neoplasms; Cattle; Cell Cycle Checkpo | 2012 |
Rebamipide abolishes Helicobacter pylori CagA-induced phospholipase D1 expression via inhibition of NFκB and suppresses invasion of gastric cancer cells.
Topics: Alanine; Anti-Ulcer Agents; Antigens, Bacterial; Bacterial Proteins; Gene Expression Regulation, Enz | 2013 |
Association of human papillomavirus type 58 variant with the risk of cervical cancer.
Topics: Adult; Alanine; Base Sequence; Cysteine; Female; Genetic Variation; Glycine; Hong Kong; Humans; Midd | 2002 |
Clinical utility of grading criteria for submucosal invasion in the prognosis of T1 colorectal carcinomas.
Topics: Adult; Aged; Aged, 80 and over; Alanine; alpha Catenin; Cadherins; Colorectal Neoplasms; Cytoskeleta | 2003 |
Ex vivo proton MR spectroscopy (1H-MRS) for evaluation of human gastric carcinoma.
Topics: Adenocarcinoma; Alanine; Choline; Feasibility Studies; Humans; Lipid Metabolism; Magnetic Resonance | 2004 |
[Proton magnetic resonance spectroscopy (1H-MRS) for the diagnosis of brain tumors and the evaluation of treatment].
Topics: Acetates; Alanine; Amino Acids; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Glutami | 2005 |
Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells.
Topics: Adenoviridae; Alanine; Animals; Arginine; Blotting, Western; Breast Neoplasms; Cell Adhesion; Cell L | 2005 |
Sidechain and backbone requirements for anti-invasive activity of laminin peptide 11.
Topics: Alanine; Animals; Basement Membrane; Drug Design; Female; Laminin; Lung Neoplasms; Magnetic Resonanc | 1998 |
Elastase activities of human bladder cancer cell lines derived from high grade invasive tumours.
Topics: Alanine; Animals; Carcinoma, Transitional Cell; Cell Line; Coumarins; Humans; Membrane Proteins; Mic | 1989 |