Page last updated: 2024-11-08

alanine and Intestinal Obstruction

alanine has been researched along with Intestinal Obstruction in 3 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Intestinal Obstruction: Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL.

Research Excerpts

ExcerptRelevanceReference
"Primary outcome measures were adverse events, plasma and cerebrospinal fluid Abeta levels, vital signs, electrocardiographic data, and laboratory safety test results."2.73Phase 2 safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease. ( Aisen, PS; Becerra, L; Clark, CM; Dean, RA; Farlow, MR; Fleisher, AS; Galvin, JE; Peskind, ER; Quinn, JF; Raman, R; Sherzai, A; Siemers, ER; Sowell, BB; Thal, LJ, 2008)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fleisher, AS1
Raman, R1
Siemers, ER1
Becerra, L1
Clark, CM1
Dean, RA1
Farlow, MR1
Galvin, JE1
Peskind, ER1
Quinn, JF1
Sherzai, A1
Sowell, BB1
Aisen, PS1
Thal, LJ1
Johnston, JK1
Freeman, DE1
Gillette, D1
Soma, LR1
Hajjar, JJ1
Van Linda, B1
Fucci, J1
Tomicic, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
LY450139: Tolerability and Biomarker Assessment in Subjects With Mild to Moderate Alzheimer's Disease[NCT00244322]Phase 245 participants Interventional2005-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for alanine and Intestinal Obstruction

ArticleYear
Phase 2 safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease.
    Archives of neurology, 2008, Volume: 65, Issue:8

    Topics: Aged; Aged, 80 and over; Alanine; Alzheimer Disease; Amnesia; Amyloid beta-Peptides; Amyloid Precurs

2008

Other Studies

2 other studies available for alanine and Intestinal Obstruction

ArticleYear
Effects of superoxide dismutase on injury induced by anoxia and reoxygenation in equine small intestine in vitro.
    American journal of veterinary research, 1991, Volume: 52, Issue:12

    Topics: Alanine; Animals; Culture Techniques; Female; Horse Diseases; Horses; Hypoxia; Intestinal Obstructio

1991
Intestinal absorption in the mechanically obstructed rat intestine: protection by prostaglandins.
    Prostaglandins, 1986, Volume: 31, Issue:1

    Topics: 16,16-Dimethylprostaglandin E2; Alanine; Animals; Arachidonic Acid; Arachidonic Acids; Clindamycin;

1986