alanine has been researched along with Intestinal Diseases in 13 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Intestinal Diseases: Pathological processes in any segment of the INTESTINE from DUODENUM to RECTUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The early-weaned pig develops intestinal atrophy and provides a readily accessible animal model for determining the role of dietary supplementation of glutamine (Gln, a major fuel for enterocytes) in preventing intestinal damage." | 7.69 | Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs. ( Knabe, DA; Meier, SA; Wu, G, 1996) |
| "Intestinal ulceration and bleeding were induced in Wistar rats by oral administration of naproxen." | 3.81 | Hydrogen sulphide protects against NSAID-enteropathy through modulation of bile and the microbiota. ( Bercik, P; Blackler, RW; Manko, A; Motta, JP; Surette, MG; Wallace, JL; Workentine, M, 2015) |
| "The early-weaned pig develops intestinal atrophy and provides a readily accessible animal model for determining the role of dietary supplementation of glutamine (Gln, a major fuel for enterocytes) in preventing intestinal damage." | 3.69 | Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs. ( Knabe, DA; Meier, SA; Wu, G, 1996) |
| "Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly-used medications, and ailments such as arthritis or heart disease, require long-term use of these drugs, which can induce gastroenteropathy with bleeding and ulcers." | 3.11 | The effect of rebamipide on non-steroidal anti-inflammatory drug-induced gastro-enteropathy: a multi-center, randomized pilot study. ( Choi, YJ; Ha, YJ; Kang, EH; Kim, HS; Kim, KJ; Kim, N; Lee, DH; Lee, YJ; Liu, F; Oh, DJ; Park, YS; Shin, CM; Yoon, H, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Oh, DJ | 1 |
| Yoon, H | 1 |
| Kim, HS | 1 |
| Choi, YJ | 1 |
| Shin, CM | 1 |
| Park, YS | 1 |
| Kim, N | 2 |
| Lee, DH | 1 |
| Ha, YJ | 1 |
| Kang, EH | 1 |
| Lee, YJ | 1 |
| Kim, KJ | 1 |
| Liu, F | 1 |
| Xu, N | 1 |
| Zhang, C | 1 |
| Jing, L | 1 |
| Mou, S | 1 |
| Cao, X | 1 |
| Yu, Z | 1 |
| Kurokawa, S | 1 |
| Katsuki, S | 1 |
| Fujita, T | 1 |
| Saitoh, Y | 1 |
| Ohta, H | 1 |
| Nishikawa, K | 1 |
| Sato, Y | 2 |
| Ohira, K | 1 |
| Yamada, M | 1 |
| Kato, M | 1 |
| Satoh, H | 1 |
| Amagase, K | 1 |
| Takeuchi, K | 2 |
| Blackler, RW | 1 |
| Motta, JP | 1 |
| Manko, A | 1 |
| Workentine, M | 1 |
| Bercik, P | 1 |
| Surette, MG | 1 |
| Wallace, JL | 1 |
| Watanabe, T | 2 |
| Takeuchi, T | 1 |
| Handa, O | 1 |
| Sakata, Y | 1 |
| Tanigawa, T | 2 |
| Shiba, M | 2 |
| Naito, Y | 1 |
| Higuchi, K | 1 |
| Fujimoto, K | 1 |
| Yoshikawa, T | 1 |
| Arakawa, T | 2 |
| Otani, K | 1 |
| Shimada, S | 1 |
| Nadatani, Y | 1 |
| Nagami, Y | 1 |
| Tanaka, F | 1 |
| Kamata, N | 1 |
| Yamagami, H | 1 |
| Tominaga, K | 1 |
| Fujiwara, Y | 1 |
| Mizukami, K | 1 |
| Murakami, K | 1 |
| Abe, T | 1 |
| Inoue, K | 1 |
| Uchida, M | 1 |
| Okimoto, T | 1 |
| Kodama, M | 1 |
| Fujioka, T | 1 |
| Satoh, J | 1 |
| Tsujikawa, T | 1 |
| Fujiyama, Y | 1 |
| Bamba, T | 1 |
| Niwa, Y | 1 |
| Nakamura, M | 1 |
| Ohmiya, N | 1 |
| Maeda, O | 1 |
| Ando, T | 1 |
| Itoh, A | 1 |
| Hirooka, Y | 1 |
| Goto, H | 1 |
| Wu, G | 1 |
| Meier, SA | 1 |
| Knabe, DA | 1 |
| Mizoguchi, H | 1 |
| Ogawa, Y | 1 |
| Kanatsu, K | 1 |
| Tanaka, A | 1 |
| Kato, S | 1 |
| Paolucci, AM | 1 |
| Spadoni, MA | 1 |
| Pennetti, V | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of the Effect of Glutamine Supplementation on Chemotherapy Induced Toxicities in Breast Cancer Patients- A Prospective, Randomised, Single Blind, Three Arm, Phase Four Prevention Trial[NCT00772824] | Phase 4 | 23 participants (Actual) | Interventional | 2007-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for alanine and Intestinal Diseases
| Article | Year |
|---|---|
Microbiota Plays a Key Role in Non-Steroidal Anti-Inflammatory Drug-Induced Small Intestinal Damage.
Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Gastrointestinal Microbiome; Hu | 2017 |
5 trials available for alanine and Intestinal Diseases
| Article | Year |
|---|---|
The effect of rebamipide on non-steroidal anti-inflammatory drug-induced gastro-enteropathy: a multi-center, randomized pilot study.
Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Humans; Intestinal Diseases; Pilot Projects; Ulcer | 2022 |
A randomized, double-blinded, placebo-controlled, multicenter trial, healing effect of rebamipide in patients with low-dose aspirin and/or non-steroidal anti-inflammatory drug induced small bowel injury.
Topics: Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Capsule Endoscop | 2014 |
A multicenter, randomized, double-blind, placebo-controlled trial of high-dose rebamipide treatment for low-dose aspirin-induced moderate-to-severe small intestinal damage.
Topics: Aged; Alanine; Anti-Ulcer Agents; Aspirin; Capsule Endoscopy; Dose-Response Relationship, Drug; Doub | 2015 |
Aspirin-induced small bowel injuries and the preventive effect of rebamipide.
Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Capsule E | 2011 |
Efficacy of rebamipide for diclofenac-induced small-intestinal mucosal injuries in healthy subjects: a prospective, randomized, double-blinded, placebo-controlled, cross-over study.
Topics: Adult; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Capsule Endoscopy; Cross | 2008 |
7 other studies available for alanine and Intestinal Diseases
| Article | Year |
|---|---|
Protective effect and mechanism of rebamipide on NSAIDs associated small bowel injury.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Claudin-1; Cytokines; Diclofenac; Disease | 2021 |
Mucosal protective agents prevent exacerbation of NSAID-induced small intestinal lesions caused by antisecretory drugs in rats.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Diclofenac; Dose-Respo | 2014 |
Hydrogen sulphide protects against NSAID-enteropathy through modulation of bile and the microbiota.
Topics: Alanine; Allyl Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile; Cell Line; Cycloox | 2015 |
Nutritional benefits of enteral alanyl-glutamine supplementation on rat small intestinal damage induced by cyclophosphamide.
Topics: Alanine; Amino Acid Transport Systems; Animals; Antineoplastic Agents, Alkylating; Biomarkers; Body | 2003 |
Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs.
Topics: Alanine; Animals; Aspartic Acid; Atrophy; Diet; Disease Models, Animal; Duodenum; Epithelium; Female | 1996 |
Protective effect of rebamipide on indomethacin-induced intestinal damage in rats.
Topics: Alanine; Ampicillin; Animals; Anti-Ulcer Agents; Bacterial Translocation; Catalase; Dose-Response Re | 2001 |
Modifications of serum-free amino acid patterns of Babinga adult pygmies after short-term feeding of a balanced diet.
Topics: Adolescent; Adult; Alanine; Amino Acids; Anti-Infective Agents; Black People; Central African Republ | 1973 |