Page last updated: 2024-11-08

alanine and Infections, Staphylococcal

alanine has been researched along with Infections, Staphylococcal in 33 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
"The kinetic interactions among glucose, alanine, and urea metabolism were studied in both normal volunteers and in patients with sepsis by means of a primed, constant infusion of stable isotopes."7.67Assessment of alanine, urea, and glucose interrelationships in normal subjects and in patients with sepsis with stable isotopic tracers. ( Klein, S; Shaw, JH; Wolfe, RR, 1985)
"The kinetic interactions among glucose, alanine, and urea metabolism were studied in both normal volunteers and in patients with sepsis by means of a primed, constant infusion of stable isotopes."3.67Assessment of alanine, urea, and glucose interrelationships in normal subjects and in patients with sepsis with stable isotopic tracers. ( Klein, S; Shaw, JH; Wolfe, RR, 1985)
"By a short-term combined prophylactic-therapeutic procedure, the following compounds were found to be active against staphylococcal infections in Swiss mice: gamma-aminobutyric acid, gamma-amino-beta-hydroxybutyric acid (GABOB), delta-amino-valeric acid (DAVA), epsilon-aminocaproic acid (EACA), trans-4-aminomethylcyclohexanecarboxylic acid (trans-AMCHA), taurine, and cysteic acid."3.65Effects of omega-amino acids and related compounds on staphylococcal infections in mice: a combined prophylactic-therapeutic procedure. ( Cook, ES; Nutini, LG; Tanaka, K; Tsuchiya, Y, 1970)
"He developed severe sepsis and acute respiratory distress syndrome (ARDS) and received intravenous high dose corticosteroid and tocilizumab to counter SARS-CoV2 associated cytokine surge."2.72Severe acute myopathy following SARS-CoV-2 infection: a case report and review of recent literature. ( Ahmed, M; Begum, SM; Islam, B; Islam, Z, 2021)
"Staphylococcus aureus infections are becoming a major global health issue due to the rapid emergence of multidrug-resistant strains."1.48A D-Alanine auxotrophic live vaccine is effective against lethal infection caused by Staphylococcus aureus. ( Bou, G; Cabral, MP; García, P; Moscoso, M; Rumbo, C, 2018)
" In a dose-response setting in immunocompetent mice maximum bactericidal effects (10,000 times reduction) of intravenously injected (99m)Tc-hLF 1-11 was seen with 40 mg/kg whereas the same dose of orally administered (99m)Tc-hLF 1-11 induced about approximately 100 times reduction."1.35Various routes of administration of (99m)Tc-labeled synthetic lactoferrin antimicrobial peptide hLF 1-11 enables monitoring and effective killing of multidrug-resistant Staphylococcus aureus infections in mice. ( Brouwer, CP; Welling, MM, 2008)
"Vancomycin was not able to substitute for penicillin G in triggering this secretion."1.26Evidence for the secretion of soluble peptidoglycans by clinical isolates of Staphylococcus aureus. ( Chatterjee, AN; Tuazon, CU; Wong, W; Young, FE; Zeiger, AR, 1982)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199012 (36.36)18.7374
1990's0 (0.00)18.2507
2000's5 (15.15)29.6817
2010's8 (24.24)24.3611
2020's8 (24.24)2.80

Authors

AuthorsStudies
Bhawsar, S1
Kale, R1
Deshpande, P1
Yeole, R1
Bhagwat, S1
Patel, M1
Mandadi, S1
Pulluru, H1
Annie, F1
Rahman, MA1
Amirkhani, A1
Parvin, F1
Chowdhury, D1
Molloy, MP1
Deva, AK1
Vickery, K1
Hu, H1
Gallagher, LA1
Shears, RK1
Fingleton, C1
Alvarez, L1
Waters, EM1
Clarke, J1
Bricio-Moreno, L1
Campbell, C1
Yadav, AK1
Razvi, F1
O'Neill, E1
O'Neill, AJ1
Cava, F1
Fey, PD1
Kadioglu, A1
O'Gara, JP1
Mullur, J1
Wang, A1
Feldweg, A1
Copaescu, A1
James, F1
Mouhtouris, E1
Vogrin, S1
Smibert, OC1
Gordon, CL1
Drewett, G1
Holmes, NE1
Trubiano, JA1
Islam, B1
Ahmed, M1
Islam, Z1
Begum, SM1
Guo, X1
Yan, T1
Rao, J1
Yue, X1
Pei, X1
Deng, J1
Sun, W1
Yang, W1
Zhang, B1
Xie, J1
Singh, M1
Chang, J1
Coffman, L1
Kim, SJ1
Moscoso, M1
García, P1
Cabral, MP1
Rumbo, C1
Bou, G1
Tkaczyk, C1
Semenova, E1
Shi, YY1
Rosenthal, K1
Oganesyan, V1
Warrener, P1
Stover, CK1
Sellman, BR1
Geng, M1
Ravichandran, A1
Escano, J1
Smith, L1
Junka, AF1
Deja, S1
Smutnicka, D1
Szymczyk, P1
Ziółkowski, G1
Bartoszewicz, M1
Młynarz, P1
Kraus, D1
Herbert, S1
Kristian, SA2
Khosravi, A1
Nizet, V1
Götz, F2
Peschel, A2
Kurokawa, K1
Gong, JH1
Ryu, KH1
Zheng, L1
Chae, JH1
Kim, MS1
Lee, BL1
Bertsche, U1
Weidenmaier, C2
Kuehner, D1
Yang, SJ1
Baur, S1
Wanner, S1
Francois, P1
Schrenzel, J1
Yeaman, MR1
Bayer, AS1
Chen, LC1
Chiang, WD1
Chen, WC1
Chen, HH1
Huang, YW1
Chen, WJ1
Lin, SB1
Collins, LV1
Faigle, M1
Van Kessel, KP1
Van Strijp, JA1
Neumeister, B1
Tsopelas, C1
Penglis, S1
Ruszkiewicz, A1
Bartholomeusz, FD1
STROMINGER, JL1
THRENN, RH1
BADDILEY, J1
BUCHANAN, JG1
MARTIN, RO1
RAJBHANDARY, UL1
ROSATO, RR1
CAMERON, JA1
Brouwer, CP1
Welling, MM1
Royle, GT1
Kettlewell, MG1
Zeiger, AR1
Wong, W1
Chatterjee, AN1
Young, FE1
Tuazon, CU1
Kasuya, H1
Kikuchi, K1
Imamura, T1
Kawashima, A1
Aihara, Y1
Ochiai, T1
Yamaguchi, K1
Fukamachi, K1
Hori, T1
Shiseki, M1
Tozuka, K1
Shoji, J1
Hinoo, H1
Wakisaka, Y1
Koizumi, K1
Mayama, M1
Shaw, JH1
Klein, S1
Wolfe, RR1
Kollonitsch, J1
Barash, L1
Kahan, FM1
Kropp, H1
Yotis, WW2
Fitzgerald, T2
Bertucci, J1
Yotis, E1
Tsuchiya, Y2
Tanaka, K2
Cook, ES2
Nutini, LG2
Berberich, NJ1
Mukkada, AJ1

Reviews

2 reviews available for alanine and Infections, Staphylococcal

ArticleYear
Severe acute myopathy following SARS-CoV-2 infection: a case report and review of recent literature.
    Skeletal muscle, 2021, 04-21, Volume: 11, Issue:1

    Topics: Adenosine Monophosphate; Adult; Alanine; Antibodies, Monoclonal, Humanized; Anticoagulants; Antivira

2021
Hormonally induced alterations in S. aureus.
    Annals of the New York Academy of Sciences, 1974, Jul-31, Volume: 236, Issue:0

    Topics: Aerobiosis; Alanine; Amino Acids; Anaerobiosis; Androsterone; Animals; Carbon Radioisotopes; Cell Wa

1974

Other Studies

31 other studies available for alanine and Infections, Staphylococcal

ArticleYear
Design and synthesis of an oral prodrug alalevonadifloxacin for the treatment of MRSA infection.
    Bioorganic & medicinal chemistry letters, 2021, 12-15, Volume: 54

    Topics: Alanine; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Design; Fluoroquinolones; Hum

2021
Comparative outcomes of combined corticosteroid and remdesivir therapy with corticosteroid monotherapy in ventilated COVID-19 patients.
    PloS one, 2022, Volume: 17, Issue:2

    Topics: Adenosine Monophosphate; Adrenal Cortex Hormones; Aged; Alanine; Cohort Studies; COVID-19; COVID-19

2022
One Step Forward with Dry Surface Biofilm (DSB) of
    International journal of molecular sciences, 2022, Oct-13, Volume: 23, Issue:20

    Topics: Alanine; Argininosuccinate Synthase; ATP-Binding Cassette Transporters; Biofilms; DNA Breaks, Double

2022
Impaired Alanine Transport or Exposure to d-Cycloserine Increases the Susceptibility of MRSA to β-lactam Antibiotics.
    The Journal of infectious diseases, 2020, 03-02, Volume: 221, Issue:6

    Topics: Alanine; Animals; Anti-Bacterial Agents; Antimetabolites; Bacterial Proteins; Bacteriological Techni

2020
A fatal case of coronavirus disease 2019 in a patient with common variable immunodeficiency.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2021, Volume: 126, Issue:1

    Topics: Adenosine Monophosphate; Adult; Alanine; Antiviral Agents; Asthma; Common Variable Immunodeficiency;

2021
The Role of Immunological and Clinical Biomarkers to Predict Clinical COVID-19 Severity and Response to Therapy-A Prospective Longitudinal Study.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Adenosine Monophosphate; Adult; Aged; Alanine; Anti-Inflammatory Agents; Antiviral Agents; Bacteremi

2021
Potent Antimicrobial and Antibiofilm Activities of Feleucin-K3 Analogs Modified by α-(4-Pentenyl)-Ala against Multidrug-Resistant Bacteria.
    Biomolecules, 2021, 05-19, Volume: 11, Issue:5

    Topics: Alanine; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Biofilms; Drug Stability;

2021
Hidden Mode of Action of Glycopeptide Antibiotics: Inhibition of Wall Teichoic Acid Biosynthesis.
    The journal of physical chemistry. B, 2017, 04-27, Volume: 121, Issue:16

    Topics: Alanine; Anti-Bacterial Agents; Biosynthetic Pathways; Cell Wall; Glycopeptides; Humans; Lipoglycope

2017
A D-Alanine auxotrophic live vaccine is effective against lethal infection caused by Staphylococcus aureus.
    Virulence, 2018, 01-01, Volume: 9, Issue:1

    Topics: Alanine; Animals; Antibodies, Bacterial; Bacteremia; Cells, Cultured; Cross Reactions; Disease Model

2018
Alanine Scanning Mutagenesis of the MEDI4893 (Suvratoxumab) Epitope Reduces Alpha Toxin Lytic Activity
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:11

    Topics: A549 Cells; Alanine; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal,

2018
Efficacious Analogs of the Lantibiotic Mutacin 1140 against a Systemic Methicillin-Resistant Staphylococcus aureus Infection.
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:12

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Bacteriocins; Drug Design;

2018
Differences in metabolic profiles of planktonic and biofilm cells in Staphylococcus aureus - (1)H Nuclear Magnetic Resonance search for candidate biomarkers.
    Acta biochimica Polonica, 2013, Volume: 60, Issue:4

    Topics: Alanine; Biofilms; Biomarkers; Butylene Glycols; Hydrogen; Isoleucine; Magnetic Resonance Spectrosco

2013
The GraRS regulatory system controls Staphylococcus aureus susceptibility to antimicrobial host defenses.
    BMC microbiology, 2008, Jun-02, Volume: 8

    Topics: Alanine; Animals; Antimicrobial Cationic Peptides; Cathelicidins; Cell Membrane; Cells, Cultured; Cy

2008
Biochemical characterization of evasion from peptidoglycan recognition by Staphylococcus aureus D-alanylated wall teichoic acid in insect innate immunity.
    Developmental and comparative immunology, 2011, Volume: 35, Issue:8

    Topics: Alanine; Amidohydrolases; Animals; Carrier Proteins; Cell Wall; Cell-Free System; Enzyme Assays; Imm

2011
Correlation of daptomycin resistance in a clinical Staphylococcus aureus strain with increased cell wall teichoic acid production and D-alanylation.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:8

    Topics: Alanine; Anti-Bacterial Agents; Bacterial Proteins; Cell Wall; Daptomycin; Drug Resistance, Bacteria

2011
Influence of alanine uptake on Staphylococcus aureus surface charge and its susceptibility to two cationic antibacterial agents, nisin and low molecular weight chitosan.
    Food chemistry, 2012, Dec-15, Volume: 135, Issue:4

    Topics: Alanine; Anti-Bacterial Agents; Chitosan; Microbial Sensitivity Tests; Molecular Weight; Nisin; Stap

2012
Staphylococcus aureus strains lacking D-alanine modifications of teichoic acids are highly susceptible to human neutrophil killing and are virulence attenuated in mice.
    The Journal of infectious diseases, 2002, Jul-15, Volume: 186, Issue:2

    Topics: Alanine; alpha-Defensins; Animals; Anti-Bacterial Agents; Bacterial Proteins; Disease Models, Animal

2002
99mTc-alafosfalin: an antibiotic peptide infection imaging agent.
    Nuclear medicine and biology, 2003, Volume: 30, Issue:2

    Topics: Alanine; Animals; Anti-Bacterial Agents; Bacterial Infections; Female; Leukocytes; Myositis; Organ S

2003
The optical configuration of the alanine residues in a uridine nucleotide and in the cell wall of Staphylococcus aureus.
    Biochimica et biophysica acta, 1959, Volume: 33, Issue:1

    Topics: Alanine; Cell Wall; Micrococcus; Nucleosides; Nucleotides; Staphylococcal Infections; Staphylococcus

1959
Teichoic acid from the walls of Staphylococcus aureus H. 2. Location of phosphate and alanine residues.
    The Biochemical journal, 1962, Volume: 85

    Topics: Alanine; Pentosephosphates; Phosphates; Staphylococcal Infections; Staphylococcus; Staphylococcus au

1962
THE BACTERIOPHAGE RECEPTOR SITES OF STAPHYLOCOCCUS AUREUS.
    Biochimica et biophysica acta, 1964, Mar-02, Volume: 83

    Topics: Alanine; Binding Sites; Cell Biology; Chromatography; Deoxyribonucleases; DNA; Glutamates; Glycine;

1964
Various routes of administration of (99m)Tc-labeled synthetic lactoferrin antimicrobial peptide hLF 1-11 enables monitoring and effective killing of multidrug-resistant Staphylococcus aureus infections in mice.
    Peptides, 2008, Volume: 29, Issue:7

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Antimicrobial Cationic Peptides; Dos

2008
Alanine metabolism in patients with chronic infection.
    The British journal of surgery, 1981, Volume: 68, Issue:1

    Topics: Abscess; Alanine; Chronic Disease; Escherichia coli Infections; Female; Half-Life; Humans; Male; Sta

1981
Evidence for the secretion of soluble peptidoglycans by clinical isolates of Staphylococcus aureus.
    Infection and immunity, 1982, Volume: 37, Issue:3

    Topics: Alanine; Culture Media; Dose-Response Relationship, Drug; Endocarditis, Bacterial; Humans; Penicilli

1982
[Two cases of methicillin-resistant Staphylococcus aureus (MRSA) sepsis following craniotomy].
    No shinkei geka. Neurological surgery, 2000, Volume: 28, Issue:5

    Topics: Adult; Aged; Alanine; Aminoglycosides; Ampicillin; Anti-Bacterial Agents; Craniotomy; Dibekacin; Dru

2000
Isolation of a new peptide antibiotic TL-119. Studies on antibiotics from the genus Bacillus. IV.
    The Journal of antibiotics, 1975, Volume: 28, Issue:2

    Topics: Alanine; Animals; Anti-Bacterial Agents; Bacillus; Leucine; Mice; Peptides; Phenylalanine; Staphyloc

1975
Assessment of alanine, urea, and glucose interrelationships in normal subjects and in patients with sepsis with stable isotopic tracers.
    Surgery, 1985, Volume: 97, Issue:5

    Topics: Adult; Aged; Alanine; Blood Glucose; Candidiasis; Carbon Isotopes; Escherichia coli Infections; Fema

1985
Letter: New antibacterial agent via photofluorination of a bacterial cell wall constituent.
    Nature, 1973, Jun-08, Volume: 243, Issue:5406

    Topics: Alanine; Animals; Anti-Bacterial Agents; Antimetabolites; Bacteria; Bacterial Infections; Cell Wall;

1973
The behavior of UV-induced coagulase-positive and negative mutants of Staphylococcus aureus.
    The Yale journal of biology and medicine, 1972, Volume: 45, Issue:2

    Topics: Alanine; Animals; Carbon Isotopes; Cell Count; Coagulase; Genetics, Microbial; Glucose; Male; Manome

1972
Effects of omega-amino acids and related compounds on staphylococcal infections in mice: a combined prophylactic-therapeutic procedure.
    Applied microbiology, 1970, Volume: 19, Issue:5

    Topics: Alanine; Amino Acids; Aminobutyrates; Aminocaproates; Animals; Culture Media; Cyclohexanecarboxylic

1970
Activity of homocarnosine and other compounds against staphylococcal infections in mice.
    Applied microbiology, 1968, Volume: 16, Issue:10

    Topics: Alanine; Amino Acids; Aminobutyrates; Aminocaproates; Animals; Brain; Dipeptides; Female; Histidine;

1968