alanine has been researched along with Hypoglycemia in 152 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study demonstrated that 6 weeks' administration of the SSRI fluoxetine can amplify a wide spectrum of ANS and metabolic counterregulatory responses during hypoglycemia in healthy individuals." | 9.13 | Effects of a selective serotonin reuptake inhibitor, fluoxetine, on counterregulatory responses to hypoglycemia in healthy individuals. ( Briscoe, VJ; Davis, SN; Dawling, S; Ertl, AC; Tate, DB, 2008) |
| "To test the hypothesis that because of sustained glycemic actions, bedtime administration of the glucagon-releasing amino acid alanine or the epinephrine-simulating beta2-adrenergic agonist terbutaline more effectively prevents nocturnal hypoglycemia than a conventional bedtime snack, we studied 15 patients with IDDM." | 9.08 | Alanine and terbutaline in the prevention of nocturnal hypoglycemia in IDDM. ( Cryer, PE; Saleh, TY, 1997) |
| "To test the hypothesis that, in contrast to administration of glucose or glucagon, administration of the amino acid Ala or of the beta 2-adrenergic agonist terbutaline produces sustained glucose recovery from hypoglycemia." | 9.07 | Alanine and terbutaline in treatment of hypoglycemia in IDDM. ( Cryer, PE; Wiethop, BV, 1993) |
| "We compared the effects of oral administration of high-dose or low-dose glutamine dipeptide (GDP), alanine (ALA), glutamine (GLN), and ALA + GLN on the blood availability of amino acids in rats submitted to insulin-induced hypoglycemia (IIH)." | 7.80 | A comparison of the effects of oral glutamine dipeptide, glutamine, and alanine on blood amino acid availability in rats submitted to insulin-induced hypoglycemia. ( Bazotte, RB; Bruschi, ML; Marques, Ade C; Minguetti-Câmara, VC; Schiavon, FP; Vilela, VR, 2014) |
| "The role of glutamine dipeptide (GDP) to prevent against prolonged insulin induced hypoglycemia (IIH) in overnight fasted rats was investigated." | 7.75 | Oral glutamine dipeptide prevents against prolonged hypoglycemia induced by Detemir insulin in rats. ( Bazotte, RB; Felisberto-Junior, AM; Gazola, VA; Geisler, SA; Manso, FC; Obici, S, 2009) |
| "Our purpose was to determine the blood amino acid concentration during insulin induced hypoglycemia (IIH) and examine if the administration of alanine or glutamine could help glycemia recovery in fasted rats." | 7.74 | Blood amino acids concentration during insulin induced hypoglycemia in rats: the role of alanine and glutamine in glucose recovery. ( Barrena, HC; Bazotte, RB; Berti, J; Boschero, AC; Carneiro, EM; Garcia, RF; Gazola, VA; Hartmann, EM; Manso, FC; Toyama, MH, 2007) |
| "We assessed the combined role of epinephrine and glucagon in regulating gluconeogenic precursor metabolism during insulin-induced hypoglycemia in the overnight-fasted, adrenalectomized, conscious dog." | 7.69 | Counterregulation by epinephrine and glucagon during insulin-induced hypoglycemia in the conscious dog. ( Adkins-Marshall, BA; Cherrington, AD; Connolly, CC; Dobbins, RL; Ivy, RE; Neal, DW; Williams, PE, 1996) |
| "The aim of the present study was to characterize the role of glucagon in countering the prolonged hypoglycemia resulting from insulin infusion and to determine whether its effect is manifest through glycogenolysis and/or gluconeogenesis." | 7.68 | Role of glucagon in countering hypoglycemia induced by insulin infusion in dogs. ( Cherrington, AD; Connolly, CC; Dobbins, RL; Neal, DW; Palladino, LJ; Parlow, AF, 1991) |
| "A case of glucagonoma syndrome with necrolytic migratory erythema, glossitis, anemia, hyperglucagonemia and a malignant, pancreatic A-cell tumour in a 68-year-old male is described." | 7.66 | Metabolic studies and glucagon gel filtration pattern before and after surgery in a case of glucagonoma syndrome. ( Berg, J; Bojs, G; Dymling, JF; Hallengren, B; Ljungberg, O; Thorell, JI; Tibblin, S; von Schenck, H, 1979) |
| "A shortage of alanine for gluconeogenesis is believed responsible for various forms of hypoglycemia and in particular ketotic hypoglycemia (KH)." | 7.66 | Hypoalaninemia and ketotic hypoglycemia: cause or consequence? ( Sadeghi-Nejad, A; Senior, B; Wolfsdorf, JI, 1982) |
| "These data indicate that intrauterine growth retardation has profound effects on postnatal growth and metabolism." | 5.27 | Altered growth, hypoglycemia, hypoalaninemia, and ketonemia in the young rat: postnatal consequences of intrauterine growth retardation. ( Bussey, ME; Finley, S; LaBarbera, A; Ogata, ES, 1985) |
| "Disopyramide (Norpace) is a recently released antiarrhythmic agent with quinidine-like actions, but structurally unique." | 5.26 | Disopyramide (Norpace)-induced hypoglycemia. ( Brown, LK; Goldberg, IJ; Rayfield, EJ, 1980) |
| "This study demonstrated that 6 weeks' administration of the SSRI fluoxetine can amplify a wide spectrum of ANS and metabolic counterregulatory responses during hypoglycemia in healthy individuals." | 5.13 | Effects of a selective serotonin reuptake inhibitor, fluoxetine, on counterregulatory responses to hypoglycemia in healthy individuals. ( Briscoe, VJ; Davis, SN; Dawling, S; Ertl, AC; Tate, DB, 2008) |
| "To test the hypothesis that because of sustained glycemic actions, bedtime administration of the glucagon-releasing amino acid alanine or the epinephrine-simulating beta2-adrenergic agonist terbutaline more effectively prevents nocturnal hypoglycemia than a conventional bedtime snack, we studied 15 patients with IDDM." | 5.08 | Alanine and terbutaline in the prevention of nocturnal hypoglycemia in IDDM. ( Cryer, PE; Saleh, TY, 1997) |
| "To test the hypothesis that, in contrast to administration of glucose or glucagon, administration of the amino acid Ala or of the beta 2-adrenergic agonist terbutaline produces sustained glucose recovery from hypoglycemia." | 5.07 | Alanine and terbutaline in treatment of hypoglycemia in IDDM. ( Cryer, PE; Wiethop, BV, 1993) |
| "Glucagon (Gcg) 1 serves a seminal physiological role in buffering against hypoglycemia, but its poor biophysical properties severely complicate its medicinal use." | 3.83 | Pyridyl-alanine as a Hydrophilic, Aromatic Element in Peptide Structural Optimization. ( DiMarchi, RD; Gelfanov, V; Liu, F; Mayer, JP; Mroz, PA; Perez-Tilve, D, 2016) |
| "We compared the effects of oral administration of high-dose or low-dose glutamine dipeptide (GDP), alanine (ALA), glutamine (GLN), and ALA + GLN on the blood availability of amino acids in rats submitted to insulin-induced hypoglycemia (IIH)." | 3.80 | A comparison of the effects of oral glutamine dipeptide, glutamine, and alanine on blood amino acid availability in rats submitted to insulin-induced hypoglycemia. ( Bazotte, RB; Bruschi, ML; Marques, Ade C; Minguetti-Câmara, VC; Schiavon, FP; Vilela, VR, 2014) |
| "The role of glutamine dipeptide (GDP) to prevent against prolonged insulin induced hypoglycemia (IIH) in overnight fasted rats was investigated." | 3.75 | Oral glutamine dipeptide prevents against prolonged hypoglycemia induced by Detemir insulin in rats. ( Bazotte, RB; Felisberto-Junior, AM; Gazola, VA; Geisler, SA; Manso, FC; Obici, S, 2009) |
| "Our purpose was to determine the blood amino acid concentration during insulin induced hypoglycemia (IIH) and examine if the administration of alanine or glutamine could help glycemia recovery in fasted rats." | 3.74 | Blood amino acids concentration during insulin induced hypoglycemia in rats: the role of alanine and glutamine in glucose recovery. ( Barrena, HC; Bazotte, RB; Berti, J; Boschero, AC; Carneiro, EM; Garcia, RF; Gazola, VA; Hartmann, EM; Manso, FC; Toyama, MH, 2007) |
| "The purpose of the present study was to investigate the effect of the combined administration of hepatic gluconeogenic substrates (glycerol + L-lactate + L-alanine + L-glutamine) on glucose recovery during insulin induced hypoglycemia (IIH), in rats." | 3.71 | Combined administration of glucose precursors is more efficient than that of glucose itself in recovery from hypoglycemia. ( Bazotte, RB; Borba-Murad, GR; Curi, R; Galletto, R; Souza, HM, 2001) |
| " Each study consisted of an equilibration (-140 to -40 min), a control (-40 to 0 min), and a test period (0 to 180 min), during which BAY R3401 (10 mg/kg), a glycogen phosphorylase inhibitor, was administered orally, either alone to create mild hypoglycemia or with peripheral glucose infusion to maintain euglycemia or create mild hyperglycemia." | 3.71 | Alpha- and beta-cell responses to small changes in plasma glucose in the conscious dog. ( Cherrington, AD; Emshwiller, MG; Flattem, N; Igawa, K; Neal, DW; Shiota, M, 2001) |
| "Hypoglycemia in man induces a marked increase in hepatic amino- to urea-N clearance." | 3.70 | Hepatic amino- to urea-N clearance and forearm amino-N exchange during hypoglycemic and euglycemic hyperinsulinemia in normal man. ( Grøfte, T; Jørgensen, JO; Møller, N; Poulsen, PL; Vilstrup, H; Wolthers, T, 1999) |
| "HII rats showed: (a) hypoglycemia and hyperinsulinemia; (b) increased hepatic capacity to produce glucose from L-alanine and L-glutamine; (c) increased hepatic ureogenesis from L-alanine and L-glutamine; and (d) increased hepatic glucose production from glycerol." | 3.70 | Hypoglycemia induced by insulin increases hepatic capacity to produce glucose from gluconeogenic amino acids. ( Bazotte, RB; Borba-Murad, GR; Fonseca, MH; Lopes, G; Souza, HM; Vardanega-Peicher, M, 1999) |
| "We assessed the combined role of epinephrine and glucagon in regulating gluconeogenic precursor metabolism during insulin-induced hypoglycemia in the overnight-fasted, adrenalectomized, conscious dog." | 3.69 | Counterregulation by epinephrine and glucagon during insulin-induced hypoglycemia in the conscious dog. ( Adkins-Marshall, BA; Cherrington, AD; Connolly, CC; Dobbins, RL; Ivy, RE; Neal, DW; Williams, PE, 1996) |
| "The aim of the present study was to characterize the role of glucagon in countering the prolonged hypoglycemia resulting from insulin infusion and to determine whether its effect is manifest through glycogenolysis and/or gluconeogenesis." | 3.68 | Role of glucagon in countering hypoglycemia induced by insulin infusion in dogs. ( Cherrington, AD; Connolly, CC; Dobbins, RL; Neal, DW; Palladino, LJ; Parlow, AF, 1991) |
| "A shortage of alanine for gluconeogenesis is believed responsible for various forms of hypoglycemia and in particular ketotic hypoglycemia (KH)." | 3.66 | Hypoalaninemia and ketotic hypoglycemia: cause or consequence? ( Sadeghi-Nejad, A; Senior, B; Wolfsdorf, JI, 1982) |
| "A case of glucagonoma syndrome with necrolytic migratory erythema, glossitis, anemia, hyperglucagonemia and a malignant, pancreatic A-cell tumour in a 68-year-old male is described." | 3.66 | Metabolic studies and glucagon gel filtration pattern before and after surgery in a case of glucagonoma syndrome. ( Berg, J; Bojs, G; Dymling, JF; Hallengren, B; Ljungberg, O; Thorell, JI; Tibblin, S; von Schenck, H, 1979) |
| " Other factors, including congestive heart failure, growth hormone deficiency, and hypoalaninemia might have contributed to the development of hypoglycemia in this patient." | 3.66 | Sulfonamide-induced hypoglycemia in chronic renal failure. ( Arem, R; Field, JB; Garber, AJ, 1983) |
| " The association of hypoglycemia and increased arterial alanine and glycine with elevated plasma glucagon implied impaired gluconeogenesis." | 3.66 | Amino acid metabolism in dogs with E. coli bacteremic shock. ( Duff, JH; Groves, AC; Woolf, LI, 1979) |
| "4 children with ketotic hypoglycemia (KH) showed during a fasting period over 24 hours significant higher decreases of serum alanine levels than normal controls." | 3.66 | [Pathogenesis of ketotic hypoglycemia (author's transl)]. ( Ploier, R; Sommer, R; Tulzer, W, 1979) |
| "To determine the mechanism by which hyperinsulinemia causes hypoglycemia in insulinoma patients, rates of glucose production and utilization, and circulating levels of insulin, glucagon, alanine, lactate, and glycerol were measured in 6 insulinoma patients during development of fasting hypoglycemia and in 8 normal volunteers studied over an identical interval." | 3.66 | Pathogenesis of hypoglycemia in insulinoma patients: suppression of hepatic glucose production by insulin. ( Gerich, JE; Haymond, MW; Mandarino, LJ; Miles, JM; Rizza, RA; Service, FJ; Verdonk, CA, 1981) |
| "Sequential determinations of glucose outflow and inflow, and rates of gluconeogenesis from alanine, before, during and after insulin-induced hypoglycemia were obtained in relation to alterations in circulating epinephrine, norepinephrine, glucagon, cortisol, and growth hormone in six normal subjects." | 3.65 | The role of adrenergic mechanisms in the substrate and hormonal response to insulin-induced hypoglycemia in man. ( Cryer, PE; Garber, AJ; Haymond, MW; Kipnis, DM; Pagliara, AS; Santiago, JV, 1976) |
| " The effect of pregnancy on the glycemic response to exogenous alanine administration during starvation was also investigated." | 3.65 | Amino acid metabolism during starvation in human pregnancy. ( Felig, P; Hendler, R; Kim, YJ; Lynch, V, 1972) |
| "For this purpose, a condition of hyperinsulinemia/hypoglycaemia was obtained with an intraperitoneal (ip) injection of regular insulin (1." | 1.35 | Evidence that L-glutamine is better than L-alanine as gluconeogenic substrate in perfused liver of weaned fasted rats submitted to short-term insulin-induced hypoglycaemia. ( Bazotte, RB; Curi, R; Felisberto-Junior, AM; Garcia, RF; Oliveira-Yamashita, F, 2009) |
| "All patients with spinal muscular atrophy and congenital myopathy and one patient with Duchenne dystrophy, but none of six healthy subjects, developed hypoglycemia." | 1.32 | Patients with severe muscle wasting are prone to develop hypoglycemia during fasting. ( Hebert, A; Laub, M; Vissing, J; Zacho, M; Ørngreen, MC, 2003) |
| " In conclusion, this study suggests that short-term administration of LA at high dosage to normal and diabetic rats causes an inhibition of gluconeogenesis secondary to an interference with hepatic fatty acid oxidation." | 1.30 | Lipoic acid acutely induces hypoglycemia in fasting nondiabetic and diabetic rats. ( Bashan, N; Gutman, A; Khamaisi, M; Potashnik, R; Rudich, A; Tritschler, HJ, 1999) |
| "From 1981 to 1994, 112 IDDM patients were on IT." | 1.29 | Long-term intensive insulin therapy in IDDM: effects on HbA1c, risk for severe and mild hypoglycaemia, status of counterregulation and awareness of hypoglycaemia. ( Annibale, B; Bartocci, L; Bolli, GB; Brunetti, P; Ciofetta, M; Di Vincenzo, A; Epifano, L; Fanelli, C; Lalli, C; Lepore, M; Modarelli, F; Pampanelli, S; Rambotti, AM; Sindaco, PD, 1996) |
| "We conclude that hypoglycemia is a major cause of death in association with diarrhea." | 1.28 | Hypoglycemia during diarrhea in childhood. Prevalence, pathophysiology, and outcome. ( Azad, AK; Bennish, ML; Phillips, RE; Rahman, O, 1990) |
| "Diazoxide treatment could be stopped at the age of 1 month." | 1.27 | Transient lactic acidosis and hyperalaninaemia associated with neonatal hyperinsulinaemic hypoglycaemia: the effects of dichloroacetate (DCA). ( Aynsley-Green, A; Jenkins, PA; Soltész, G; Weindling, AM, 1983) |
| "These data indicate that intrauterine growth retardation has profound effects on postnatal growth and metabolism." | 1.27 | Altered growth, hypoglycemia, hypoalaninemia, and ketonemia in the young rat: postnatal consequences of intrauterine growth retardation. ( Bussey, ME; Finley, S; LaBarbera, A; Ogata, ES, 1985) |
| "This hypoglycemia is not affected by treatment with adrenaline, glucagon, nicotinadenine dinucleotide (NAD), adenosine triphosphate (ATP) alanine (A), or pyruvate (P), while fructose (F) and dihydroxyacetone (DHA) slightly increase the plasma glucose concentration." | 1.27 | Studies on the site of the block in gluconeogenesis causing severe hypoglycemia in intestinal ischemia shock in rats. ( Snijders, PM; Valkenburg, PW; van der Meer, C, 1985) |
| "Disopyramide (Norpace) is a recently released antiarrhythmic agent with quinidine-like actions, but structurally unique." | 1.26 | Disopyramide (Norpace)-induced hypoglycemia. ( Brown, LK; Goldberg, IJ; Rayfield, EJ, 1980) |
| "The origin of this hypoglycemia is not clear but is probably multifactorial." | 1.26 | [Spontaneous hypoglycemia and chronic kidney insufficiency]. ( Caron, C; Langlois, M; Nawar, T; Robert, G, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 100 (65.79) | 18.7374 |
| 1990's | 25 (16.45) | 18.2507 |
| 2000's | 22 (14.47) | 29.6817 |
| 2010's | 5 (3.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Minguetti-Câmara, VC | 1 |
| Marques, Ade C | 1 |
| Schiavon, FP | 1 |
| Vilela, VR | 1 |
| Bruschi, ML | 1 |
| Bazotte, RB | 9 |
| Vashishtha, VM | 1 |
| Mroz, PA | 1 |
| Perez-Tilve, D | 1 |
| Liu, F | 1 |
| Gelfanov, V | 1 |
| DiMarchi, RD | 1 |
| Mayer, JP | 1 |
| Briscoe, VJ | 1 |
| Ertl, AC | 2 |
| Tate, DB | 1 |
| Dawling, S | 1 |
| Davis, SN | 5 |
| Oliveira-Yamashita, F | 1 |
| Garcia, RF | 2 |
| Felisberto-Junior, AM | 3 |
| Curi, R | 4 |
| Manso, FC | 2 |
| Gazola, VA | 2 |
| Obici, S | 1 |
| Geisler, SA | 1 |
| Malta, A | 1 |
| Furlan, MP | 1 |
| Vitoriano, AS | 1 |
| Barrena, HC | 3 |
| Gazola, VG | 1 |
| Rodrigues, R | 1 |
| Feitosa, KP | 1 |
| Igawa, K | 2 |
| Mugavero, M | 1 |
| Shiota, M | 2 |
| Neal, DW | 7 |
| Cherrington, AD | 11 |
| Pukrittayakamee, S | 1 |
| Krishna, S | 2 |
| Ter Kuile, F | 1 |
| Wilaiwan, O | 1 |
| Williamson, DH | 2 |
| White, NJ | 2 |
| Halonen, P | 1 |
| Salo, MK | 1 |
| Schmiegelow, K | 1 |
| Mäkipernaa, A | 1 |
| Souza, HM | 2 |
| Borba-Murad, GR | 3 |
| Galletto, R | 1 |
| VANTAGGI COZZARI, L | 1 |
| BRUNI, A | 1 |
| CONTESSA, AR | 1 |
| CHEN, KK | 1 |
| FLEMING, WJ | 1 |
| LIN, TM | 1 |
| DEKABAN, A | 1 |
| FIELD, JB | 2 |
| STEVENS, H | 1 |
| FREINKEL, N | 4 |
| COHEN, AK | 1 |
| ARKY, RA | 1 |
| FOSTER, AE | 1 |
| Ørngreen, MC | 1 |
| Zacho, M | 1 |
| Hebert, A | 1 |
| Laub, M | 1 |
| Vissing, J | 1 |
| Evans, ML | 1 |
| Hopkins, D | 1 |
| Macdonald, IA | 1 |
| Amiel, SA | 1 |
| Lubow, JM | 1 |
| Piñón, IG | 1 |
| Avogaro, A | 1 |
| Cobelli, C | 1 |
| Treeson, DM | 1 |
| Mandeville, KA | 1 |
| Toffolo, G | 1 |
| Boyle, PJ | 1 |
| Meyer, C | 1 |
| Saar, P | 1 |
| Soydan, N | 1 |
| Eckhard, M | 1 |
| Bretzel, RG | 1 |
| Gerich, J | 1 |
| Linn, T | 1 |
| Bodamer, OA | 1 |
| Hussein, K | 1 |
| Morris, AA | 1 |
| Langhans, CD | 1 |
| Rating, D | 1 |
| Mayatepek, E | 1 |
| Leonard, JV | 1 |
| Stanley, CA | 1 |
| Hartmann, EM | 1 |
| Berti, J | 1 |
| Toyama, MH | 1 |
| Boschero, AC | 1 |
| Carneiro, EM | 1 |
| Porcellati, F | 2 |
| Pampanelli, S | 4 |
| Rossetti, P | 2 |
| Busciantella Ricci, N | 1 |
| Marzotti, S | 1 |
| Lucidi, P | 1 |
| Santeusanio, F | 3 |
| Bolli, GB | 7 |
| Fanelli, CG | 2 |
| Ricci, NB | 1 |
| Candeloro, P | 1 |
| Cioli, P | 1 |
| Fortney, SR | 1 |
| Clark, DA | 1 |
| Stein, E | 1 |
| Lager, I | 1 |
| Jagenburg, R | 1 |
| von Schenck, H | 2 |
| Smith, U | 1 |
| Metzger, BE | 2 |
| Ravnikar, V | 1 |
| Vileisis, RA | 1 |
| Diamond, MP | 1 |
| Suhrer, JH | 1 |
| Williams, PE | 3 |
| Lacy, WW | 1 |
| Rizza, RA | 1 |
| Haymond, MW | 6 |
| Verdonk, CA | 1 |
| Mandarino, LJ | 1 |
| Miles, JM | 1 |
| Service, FJ | 1 |
| Gerich, JE | 3 |
| Pagliara, AS | 5 |
| Arem, R | 1 |
| Garber, AJ | 3 |
| Warrell, DA | 1 |
| Chanthavanich, P | 1 |
| Looareesuwan, S | 1 |
| Warrell, MJ | 1 |
| Turner, RC | 1 |
| Hansen, IL | 1 |
| Levy, MM | 1 |
| Kerr, DS | 2 |
| Brunetti, P | 6 |
| Bueti, A | 1 |
| Antonella, MA | 1 |
| Calabrese, G | 1 |
| Fabietti, PG | 1 |
| Massi Benedetti, M | 1 |
| Aynsley-Green, A | 4 |
| Jenkins, P | 1 |
| Tronier, B | 1 |
| Heding, LG | 1 |
| Soltész, G | 4 |
| Jenkins, PA | 2 |
| Weindling, AM | 1 |
| Sann, L | 2 |
| Dellamonica, C | 1 |
| Goldberg, IJ | 1 |
| Brown, LK | 1 |
| Rayfield, EJ | 1 |
| Böhles, H | 1 |
| Wolfsdorf, JI | 2 |
| Sadeghi-Nejad, A | 1 |
| Senior, B | 2 |
| Gauthier, C | 1 |
| Hetenyi, G | 1 |
| Allison, CW | 1 |
| Cater, JI | 1 |
| Gray, IG | 1 |
| Staziker, AC | 1 |
| Sabel, KG | 1 |
| Olegård, R | 1 |
| Mellander, M | 1 |
| Hildingsson, K | 1 |
| Picou, DI | 1 |
| Søvik, O | 1 |
| Selvig, S | 1 |
| Finne, PH | 1 |
| Teijema, HL | 1 |
| van Gelderen, HH | 1 |
| Giesberts, MA | 1 |
| Bruce, AK | 1 |
| Jacobsen, E | 1 |
| Dossing, H | 1 |
| Kondrup, J | 1 |
| Colburn, C | 1 |
| Dobbins, R | 1 |
| Nadeau, S | 1 |
| Neal, D | 1 |
| Williams, P | 2 |
| Molina, PE | 2 |
| Jabbour, K | 1 |
| Abumrad, NN | 2 |
| Rattarasarn, C | 1 |
| Dagogo-Jack, S | 1 |
| Zachwieja, JJ | 1 |
| Cryer, PE | 10 |
| Goldstein, RE | 1 |
| Jacobs, J | 1 |
| Price, L | 1 |
| Towler, DA | 1 |
| Havlin, CE | 2 |
| Craft, S | 1 |
| Cryer, P | 1 |
| Fanelli, C | 2 |
| Di Vincenzo, A | 2 |
| Modarelli, F | 2 |
| Lepore, M | 3 |
| Ciofetta, M | 3 |
| Epifano, L | 2 |
| Wiethop, BV | 1 |
| Torlone, E | 2 |
| Ialli, C | 1 |
| Del Sindaco, P | 1 |
| Bartocci, L | 2 |
| Lalli, C | 1 |
| Sindaco, PD | 1 |
| Rambotti, AM | 1 |
| Annibale, B | 1 |
| Connolly, CC | 4 |
| Ivy, RE | 1 |
| Adkins-Marshall, BA | 2 |
| Dobbins, RL | 2 |
| Myers, SR | 1 |
| Hastings, JR | 1 |
| Maggs, DG | 1 |
| Jacob, R | 1 |
| Rife, F | 1 |
| Caprio, S | 2 |
| Tamborlane, WV | 2 |
| Sherwin, RS | 2 |
| Saleh, TY | 1 |
| Cersosimo, E | 1 |
| Khamaisi, M | 1 |
| Rudich, A | 1 |
| Potashnik, R | 1 |
| Tritschler, HJ | 1 |
| Gutman, A | 1 |
| Bashan, N | 1 |
| Grøfte, T | 1 |
| Wolthers, T | 1 |
| Jørgensen, JO | 1 |
| Poulsen, PL | 1 |
| Vilstrup, H | 1 |
| Møller, N | 1 |
| Jackson, PA | 1 |
| Cardin, S | 1 |
| Coffey, CS | 1 |
| Allen, EJ | 1 |
| Penaloza, AR | 1 |
| Snead, WL | 1 |
| Vardanega-Peicher, M | 2 |
| Lopes, G | 1 |
| Fonseca, MH | 1 |
| Flattem, N | 1 |
| Emshwiller, MG | 1 |
| Galassetti, P | 2 |
| Mann, S | 1 |
| Tate, D | 2 |
| Neill, RA | 1 |
| Costa, F | 1 |
| Wasserman, DH | 3 |
| de Souza, HM | 1 |
| Ceddia, RB | 1 |
| Neill, AR | 1 |
| Coker, RH | 1 |
| Koyama, Y | 1 |
| Denny, JC | 1 |
| Camacho, RC | 1 |
| Lacy, DB | 2 |
| Santiago, JV | 2 |
| Kipnis, DM | 2 |
| Maclaren, NK | 1 |
| Cowles, C | 1 |
| Ozand, PT | 1 |
| Shuttee, R | 1 |
| Cornblath, M | 1 |
| Moncrieff, MW | 1 |
| Ratter, S | 1 |
| Benedict, CR | 1 |
| Storrs, CN | 1 |
| Thorell, JI | 1 |
| Berg, J | 1 |
| Bojs, G | 1 |
| Dymling, JF | 1 |
| Hallengren, B | 1 |
| Ljungberg, O | 1 |
| Tibblin, S | 1 |
| Woolf, LI | 1 |
| Groves, AC | 1 |
| Duff, JH | 1 |
| Dahlquist, G | 1 |
| Gentz, J | 1 |
| Hagenfeldt, L | 1 |
| Larsson, A | 1 |
| Löw, H | 1 |
| Persson, B | 1 |
| Zetterström, R | 1 |
| Ploier, R | 1 |
| Tulzer, W | 1 |
| Sommer, R | 1 |
| Plovnick, H | 1 |
| Ruderman, NB | 2 |
| Aoki, T | 1 |
| Chideckel, EW | 1 |
| Poffenbarger, PL | 1 |
| Clarke, WL | 1 |
| Thomas, L | 1 |
| Ben-Galim, E | 1 |
| Strauss, AW | 1 |
| Arnold, KJ | 1 |
| Bier, DM | 2 |
| Assan, R | 1 |
| Heuclin, C | 1 |
| Girard, JR | 1 |
| Reach, G | 1 |
| Basdevant, A | 1 |
| Predine, J | 1 |
| Semiginovský, B | 1 |
| Sobotka, P | 1 |
| Jakoubek, B | 1 |
| Langlois, M | 1 |
| Robert, G | 1 |
| Nawar, T | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacokinetics and Safety of Treatment With Paracetamol in Children and Adults With Spinal Muscular Atrophy and Cerebral Palsy[NCT03648658] | Phase 4 | 48 participants (Anticipated) | Interventional | 2019-02-18 | Recruiting | ||
| Do Preoperative Carbohydrate Drinks Prevent Preoperative Catabolism in Mothers Undergoing Elective Caesarean Section? A Randomised Controlled Study[NCT03220997] | 200 participants (Anticipated) | Interventional | 2017-08-31 | Not yet recruiting | |||
| Restoration of Hypoglycemia Awareness With Metoclopramide[NCT03970720] | Phase 2 | 36 participants (Anticipated) | Interventional | 2019-05-28 | Recruiting | ||
| Evaluation of p21 Induction and Molecular Pathways Related to Short-term Fasting Response[NCT04259879] | 20 participants (Actual) | Interventional | 2016-04-07 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for alanine and Hypoglycemia
| Article | Year |
|---|---|
Ketotic hypoglycaemia.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Adolescent; Adrenocorticotropic Hormone; Adult; Alan | 1983 |
[The diagnosis of hypoglycemia in childhood (author's transl)].
Topics: Adolescent; Age Factors; Alanine; Child; Child, Preschool; Deoxyglucose; Glucagon; Glucose Tolerance | 1980 |
Amino acid metabolism in man.
Topics: Alanine; Amino Acids; Brain; Diabetes Mellitus; Erythrocytes; Glucagon; Glucocorticoids; Gluconeogen | 1975 |
Muscle amino acid metabolism and gluconeogenesis.
Topics: Adaptation, Physiological; Alanine; Amino Acids; Aminoacylation; Animals; Fasting; Forearm; Gluconeo | 1975 |
Fasting hypoglycemia.
Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenocorticotropic Hormone; Ad | 1973 |
Thiamine-responsive lactic acidosis.
Topics: Acidosis; Alanine; Biotin; Carbohydrate Metabolism, Inborn Errors; Dietary Carbohydrates; Female; Hu | 1974 |
Starvation in pregnancy: metabolic changes.
Topics: Abortion, Therapeutic; Acidosis; Alanine; Amino Acids; Amniocentesis; Amniotic Fluid; Blood; Blood G | 1973 |
Biochemistry of hypogylcin.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Carbon Radioisotopes; Crystallization; Cyclopropanes; | 1974 |
Metabolic adaptation to pregnancy.
Topics: Abortion, Induced; Alanine; Amniotic Fluid; Blood Glucose; Fatty Acids, Nonesterified; Female; Fetus | 1974 |
[New etiologic approach to periodic ketoacidosis in children].
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Butyrates; Carbohydrate Metabolism, Inborn Errors; Ch | 1971 |
6 trials available for alanine and Hypoglycemia
| Article | Year |
|---|---|
Effects of a selective serotonin reuptake inhibitor, fluoxetine, on counterregulatory responses to hypoglycemia in healthy individuals.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Autonomic Nervous System; Blood Glucose; Blood Pressure; Fatt | 2008 |
Different brain responses to hypoglycemia induced by equipotent doses of the long-acting insulin analog detemir and human regular insulin in humans.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Brain; C-Peptide; Dose-Response Relationship, | 2008 |
Effect of beta-blockade on hormone release during hypoglycaemia in insulin-dependent diabetics.
Topics: Adrenergic beta-Antagonists; Adult; Alanine; Blood Glucose; Catecholamines; Diabetes Mellitus; Femal | 1980 |
Alanine and terbutaline in treatment of hypoglycemia in IDDM.
Topics: 3-Hydroxybutyric Acid; Administration, Oral; Alanine; Blood Glucose; C-Peptide; Diabetes Mellitus, T | 1993 |
Alanine and terbutaline in the prevention of nocturnal hypoglycemia in IDDM.
Topics: Adrenergic beta-Agonists; Adult; Alanine; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1 | 1997 |
Ketotic hypoglycemia of childhood--a clinical trial of several unifying etiological hypotheses.
Topics: Alanine; Blood Glucose; Catecholamines; Child; Child, Preschool; Clinical Trials as Topic; Dietary F | 1979 |
136 other studies available for alanine and Hypoglycemia
| Article | Year |
|---|---|
A comparison of the effects of oral glutamine dipeptide, glutamine, and alanine on blood amino acid availability in rats submitted to insulin-induced hypoglycemia.
Topics: Administration, Oral; Alanine; Amino Acids; Animals; Dietary Supplements; Dipeptides; Glutamine; Hyp | 2014 |
Outbreaks of Hypoglycemic Encephalopathy in Muzaffarpur, India: Are These Caused by Toxins in Litchi Fruit?: The Counterpoint.
Topics: Alanine; Brain Diseases; Child; Cyclopropanes; Disease Outbreaks; Fruit; Humans; Hypoglycemia; Hypog | 2016 |
Pyridyl-alanine as a Hydrophilic, Aromatic Element in Peptide Structural Optimization.
Topics: Alanine; Animals; Cyclic AMP; Drug Stability; Glucagon; HEK293 Cells; Humans; Hypoglycemia; Male; Py | 2016 |
Evidence that L-glutamine is better than L-alanine as gluconeogenic substrate in perfused liver of weaned fasted rats submitted to short-term insulin-induced hypoglycaemia.
Topics: Alanine; Animals; Fasting; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hyperinsulinism; Hypoglyce | 2009 |
Oral glutamine dipeptide prevents against prolonged hypoglycemia induced by Detemir insulin in rats.
Topics: Alanine; Animals; Area Under Curve; Blood Glucose; Dipeptides; Gluconeogenesis; Glutamine; Hypoglyce | 2009 |
Insulin sensitivity and liver glucose production in the rat are influenced by lifetime food restriction.
Topics: Alanine; Animals; Food Deprivation; Gluconeogenesis; Glucose; Glycogenolysis; Hypoglycemia; Insulin; | 2010 |
Comparative effects of short-term and long-term insulin-induced hypoglycemia on glucose production in the perfused livers of weaned rats.
Topics: Alanine; Animals; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hypoglycemia; Hypoglycemic Agents; | 2011 |
Insulin sensitively controls the glucagon response to mild hypoglycemia in the dog.
Topics: Alanine; Animals; Blood Glucose; Consciousness; Dihydropyridines; Dogs; Fasting; Fatty Acids, Nonest | 2002 |
Alanine metabolism in acute falciparum malaria.
Topics: Acute Disease; Adult; Alanine; Blood Glucose; Female; Humans; Hypoglycemia; Indocyanine Green; Liver | 2002 |
Investigation of the mechanisms of therapy-related hypoglycaemia in children with acute lymphoblastic leukaemia.
Topics: Adolescent; Alanine; Antineoplastic Combined Chemotherapy Protocols; Blood Glucose; Carnitine; Child | 2003 |
Combined administration of glucose precursors is more efficient than that of glucose itself in recovery from hypoglycemia.
Topics: Alanine; Animals; Blood Glucose; Drug Combinations; Glucose; Glycerol; Hypoglycemia; Lactic Acid; Li | 2001 |
[Behavior of the rat diaphragm isolated during the hypoglycemic state induced by hypoglycin A].
Topics: Alanine; Animals; Diaphragm; Hypoglycemia; Hypoglycemic Agents; Hypoglycins; Muscles; Rats | 1960 |
Action of hypoglycin A on blood sugar, gastric secretion and adipose tissue.
Topics: Adipose Tissue; Alanine; Blood Glucose; Gastric Fistula; Gastric Juice; Humans; Hypoglycemia; Hypogl | 1961 |
Familial idiopathic hypoglycemia: neurological complications.
Topics: Alanine; Galactose; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Leucine; Nervous System | 1962 |
ALCOHOL HYPOGLYCEMIA. II. A POSTULATED MECHANISM OF ACTION BASED ON EXPERIMENTS WITH RAT LIVER SLICES.
Topics: Alanine; Amino Acids; Aspartic Acid; Autoradiography; Carbohydrate Metabolism; Carbon Dioxide; Carbo | 1965 |
Patients with severe muscle wasting are prone to develop hypoglycemia during fasting.
Topics: Adult; Alanine; Blood Glucose; Body Weight; Fasting; Fatty Acids, Nonesterified; Female; Glycerol; H | 2003 |
Alanine infusion during hypoglycaemia partly supports cognitive performance in healthy human subjects.
Topics: Adult; Alanine; Blood Glucose; Cognition Disorders; Glucose Clamp Technique; Hormones; Humans; Hypog | 2004 |
Brain oxygen utilization is unchanged by hypoglycemia in normal humans: lactate, alanine, and leucine uptake are not sufficient to offset energy deficit.
Topics: Adult; Alanine; Blood Glucose; Brain; Cerebrovascular Circulation; Energy Metabolism; Female; Glucos | 2006 |
A potential important role of skeletal muscle in human counterregulation of hypoglycemia.
Topics: Adult; Alanine; Blood Glucose; Female; Forearm; Gluconeogenesis; Glucose; Glycogenolysis; Humans; Hy | 2005 |
Glucose and leucine kinetics in idiopathic ketotic hypoglycaemia.
Topics: Alanine; Amino Acids, Branched-Chain; Basal Metabolism; Calorimetry, Indirect; Carnitine; Case-Contr | 2006 |
Parsing ketotic hypoglycaemia.
Topics: Alanine; Child, Preschool; Fasting; Glycogen Synthase; Humans; Hypoglycemia; Infant; Insulin; Ketosi | 2006 |
Blood amino acids concentration during insulin induced hypoglycemia in rats: the role of alanine and glutamine in glucose recovery.
Topics: Alanine; Amino Acids; Animals; Blood Glucose; Drug Combinations; Gluconeogenesis; Glutamine; Hypogly | 2007 |
Effect of the amino acid alanine on glucagon secretion in non-diabetic and type 1 diabetic subjects during hyperinsulinaemic euglycaemia, hypoglycaemia and post-hypoglycaemic hyperglycaemia.
Topics: Adolescent; Adult; Alanine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Female | 2007 |
Inhibition of gluconeogenesis by hydrazine administration in rats.
Topics: Alanine; Animals; Aspartic Acid; Blood Glucose; Carbon Isotopes; Gluconeogenesis; Hydrazines; Hypogl | 1967 |
"Accelerated starvation" and the skipped breakfast in late normal pregnancy.
Topics: 3-Hydroxybutyric Acid; Alanine; Blood Glucose; Diabetes Mellitus; Fasting; Fatty Acids, Nonesterifie | 1982 |
Contribution of the liver and extrasplanchnic tissues to the hypoglycemic action of dichloroacetate in the conscious dog.
Topics: Acetates; Alanine; Animals; Dichloroacetic Acid; Dogs; Epinephrine; Glucagon; Glucose; Hypoglycemia; | 1982 |
Pathogenesis of hypoglycemia in insulinoma patients: suppression of hepatic glucose production by insulin.
Topics: Adenoma, Islet Cell; Adult; Aged; Alanine; Blood Glucose; Female; Glucagon; Glucose; Glycerol; Human | 1981 |
Sulfonamide-induced hypoglycemia in chronic renal failure.
Topics: Aged; Alanine; Female; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Heart Failure; Hum | 1983 |
Severe hypoglycemia and hyperinsulinemia in falciparum malaria.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Alanine; Blood Glucose; Brain Diseases; C-Peptide; Child; | 1983 |
Differential diagnosis of hypoglycemia in children by responses to fasting and 2-deoxyglucose.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Alanine; Blood Glucose; Child; Child, Preschool; Deoxy Sug | 1983 |
Metabolic effects of intensified insulin therapy.
Topics: Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Drug Administration Schedule; Fatty Acids, Nonest | 1984 |
Plasma proinsulin and C-peptide concentrations in children with hyperinsulinaemic hypoglycaemia.
Topics: Alanine; C-Peptide; Child; Female; Humans; Hypoglycemia; Infant, Newborn; Insulin; Insulinoma; Lacta | 1984 |
Hypoglycaemia in classical maple syrup urine disease is not due to hyperinsulinism.
Topics: Alanine; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Insulin; Maple Syru | 1983 |
Transient lactic acidosis and hyperalaninaemia associated with neonatal hyperinsulinaemic hypoglycaemia: the effects of dichloroacetate (DCA).
Topics: Acetates; Acidosis; Alanine; Diazoxide; Dichloroacetic Acid; Humans; Hypoglycemia; Infant; Infant, N | 1983 |
Hyperammonemia in hypoglycemic preterm neonates.
Topics: Alanine; Ammonia; Blood Glucose; Blood Urea Nitrogen; Gluconeogenesis; Humans; Hypoglycemia; Infant, | 1983 |
Disopyramide (Norpace)-induced hypoglycemia.
Topics: Aged; Alanine; Atrial Flutter; Disopyramide; Female; Glucagon; Gluconeogenesis; Glucose Tolerance Te | 1980 |
Hypoalaninemia and ketotic hypoglycemia: cause or consequence?
Topics: Acidosis; Adolescent; Adult; Alanine; Blood Glucose; Child; Child, Preschool; Fasting; Female; Human | 1982 |
Origin of glucose related in the regulatory response against hypoglycemia.
Topics: Alanine; Animals; Blood Glucose; Dogs; Fasting; Female; Glucagon; Gluconeogenesis; Glucose; Hypoglyc | 1982 |
Pre-operative starvation in children. The role of alanine in blood glucose homeostasis.
Topics: Alanine; Blood Glucose; Child; Child, Preschool; Fasting; Female; Homeostasis; Humans; Hypoglycemia; | 1982 |
Interrelation between fatty acid oxidation and control of gluconeogenic substrates in small-for-gestational-age (SGA) infants with hypoglycemia and with normoglycemia.
Topics: Alanine; Blood Glucose; Fat Emulsions, Intravenous; Fatty Acids; Female; Gluconeogenesis; Glycerol; | 1982 |
Fasting glucose production in the smaller of twins with epinephrine-deficient hypoglycemia.
Topics: Alanine; Amino Acids; Birth Weight; Blood Glucose; Child; Child, Preschool; Epinephrine; Fasting; Fe | 1981 |
Metabolic responses to alanine in small-for-gestational age infants: developmental aspects.
Topics: Alanine; Female; Glucagon; Gluconeogenesis; Glucose; Humans; Hypoglycemia; Infant, Newborn; Infant, | 1981 |
Hypoketosis as a cause of symptoms in childhood hypoglycemia.
Topics: Adolescent; Alanine; Child; Child, Preschool; Fasting; Gluconeogenesis; Glutamine; Humans; Hypoglyce | 1980 |
Hypoglycaemia in spinal muscular atrophy.
Topics: Adolescent; Adult; Alanine; Blood Glucose; Child; Fasting; Female; Gluconeogenesis; Glucose; Humans; | 1995 |
Evidence that the brain of the conscious dog is insulin sensitive.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine; Animals; Brain; Cerebrovascular Circulation; Consciou | 1995 |
Effect of acute ethanol intoxication on glucoregulation during prolonged insulin-induced hypoglycemia.
Topics: Alanine; Alcoholic Intoxication; Animals; Blood Glucose; Dogs; Ethanol; Fatty Acids, Nonesterified; | 1994 |
Hypoglycemia-induced autonomic failure in IDDM is specific for stimulus of hypoglycemia and is not attributable to prior autonomic activation.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Analysis of Variance; Autonomic Nervous System; Blood Glucose | 1994 |
Effects of insulin on the counterregulatory response to equivalent hypoglycemia in normal females.
Topics: Adult; Alanine; Analysis of Variance; Blood Glucose; Epinephrine; Fatty Acids, Nonesterified; Female | 1993 |
Mechanism of awareness of hypoglycemia. Perception of neurogenic (predominantly cholinergic) rather than neuroglycopenic symptoms.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Atropine; Autonomic Nervous System; Awareness; Blood Glucose; | 1993 |
Post-hypoglycaemic hyperketonaemia does not contribute to brain metabolism during insulin-induced hypoglycaemia in humans.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Brain; Cognition; Diabetes Mellitus, Type 1; Female; Glycerol | 1993 |
Improved postprandial metabolic control after subcutaneous injection of a short-acting insulin analog in IDDM of short duration with residual pancreatic beta-cell function.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Drug Adm | 1995 |
Long-term intensive insulin therapy in IDDM: effects on HbA1c, risk for severe and mild hypoglycaemia, status of counterregulation and awareness of hypoglycaemia.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Fatty | 1996 |
Counterregulation by epinephrine and glucagon during insulin-induced hypoglycemia in the conscious dog.
Topics: Adrenalectomy; Alanine; Animals; Blood Glucose; Dogs; Epinephrine; Female; Glucagon; Gluconeogenesis | 1996 |
In the absence of counterregulatory hormones, the increase in hepatic glucose production during insulin-induced hypoglycemia in the dog is initiated in the liver rather than the brain.
Topics: Adrenalectomy; Alanine; Animals; Blood Glucose; Brain; Dogs; Fatty Acids, Nonesterified; Female; Glu | 1996 |
Counterregulation in peripheral tissues: effect of systemic hypoglycemia on levels of substrates and catecholamines in human skeletal muscle and adipose tissue.
Topics: Adipose Tissue; Adolescent; Adult; Alanine; Blood Glucose; Body Weight; Epinephrine; Extracellular S | 1997 |
Renal lactate metabolism and gluconeogenesis during insulin-induced hypoglycemia.
Topics: Alanine; Animals; Blood Flow Velocity; Blood Glucose; Dogs; Epinephrine; Gluconeogenesis; Glucose; G | 1998 |
Lipoic acid acutely induces hypoglycemia in fasting nondiabetic and diabetic rats.
Topics: 3-Hydroxybutyric Acid; Alanine; Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; | 1999 |
Hepatic amino- to urea-N clearance and forearm amino-N exchange during hypoglycemic and euglycemic hyperinsulinemia in normal man.
Topics: Adult; Alanine; Amino Acids; Blood Glucose; Forearm; Glucagon; Glucose Clamp Technique; Humans; Hype | 1999 |
Effect of hepatic denervation on the counterregulatory response to insulin-induced hypoglycemia in the dog.
Topics: 3-Hydroxybutyric Acid; Alanine; Animals; Blood Glucose; Cold Temperature; Consciousness; Dogs; Epine | 2000 |
Hypoglycemia induced by insulin increases hepatic capacity to produce glucose from gluconeogenic amino acids.
Topics: Alanine; Animals; Gluconeogenesis; Glucose; Glutamine; Hypoglycemia; Insulin; Liver; Liver Glycogen; | 1999 |
Alpha- and beta-cell responses to small changes in plasma glucose in the conscious dog.
Topics: Alanine; Animals; Arteries; Blood Glucose; Dogs; Female; Gluconeogenesis; Glucose; Glycerol; Glycoge | 2001 |
Effects of antecedent prolonged exercise on subsequent counterregulatory responses to hypoglycemia.
Topics: 3-Hydroxybutyric Acid; Adrenocorticotropic Hormone; Adult; Alanine; Blood Glucose; Blood Pressure; E | 2001 |
Rat liver responsiveness to gluconeogenic substrates during insulin-induced hypoglycemia.
Topics: Alanine; Animals; Blood Glucose; Cryoprotective Agents; Gluconeogenesis; Glucose; Glutamine; Glycero | 2001 |
Sexual dimorphism in counterregulatory responses to hypoglycemia after antecedent exercise.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Blood Pressure; Body Mass Index; Epinephrine; | 2001 |
Prevention of overt hypoglycemia during exercise: stimulation of endogenous glucose production independent of hepatic catecholamine action and changes in pancreatic hormone concentration.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alanine; Animals; Blood Glucose; Dogs; Ep | 2002 |
The role of adrenergic mechanisms in the substrate and hormonal response to insulin-induced hypoglycemia in man.
Topics: Adrenergic alpha-Agonists; Adult; Alanine; Epinephrine; Glucagon; Gluconeogenesis; Glucose; Growth H | 1976 |
Glycerol intolerance in a child with intermittent hypoglycemia.
Topics: Alanine; Carbon Radioisotopes; Child, Preschool; Consciousness; Fructose; Fructose-Bisphosphatase; G | 1975 |
Isolated ACTH deficiency. Metabolic and endocrine studies in a 7-year-old boy.
Topics: Adrenocorticotropic Hormone; Alanine; Child; Humans; Hypoglycemia; Hypothalamo-Hypophyseal System; M | 1978 |
Metabolic studies and glucagon gel filtration pattern before and after surgery in a case of glucagonoma syndrome.
Topics: Adenoma, Islet Cell; Aged; Alanine; Anemia; Arginine; Chromatography, Gel; Erythema; Glossitis; Gluc | 1979 |
Amino acid metabolism in dogs with E. coli bacteremic shock.
Topics: Alanine; Amino Acids; Animals; Blood Gas Analysis; Blood Pressure; Blood Urea Nitrogen; Dogs; Escher | 1979 |
[Pathogenesis of ketotic hypoglycemia (author's transl)].
Topics: Acidosis; Alanine; Child; Child, Preschool; Deoxyglucose; Diazoxide; Epinephrine; Fasting; Female; H | 1979 |
Non-beta-cell tumor hypoglycemia associated with increased nonsuppressible insulin-like protein (NSILP).
Topics: Aged; Alanine; Amino Acids; Blood Glucose; Fasting; Female; Glucagon; Humans; Hypoglycemia; Insulin; | 1979 |
Adrenergic mechanisms in recovery from hypoglycemia in man: adrenergic blockade.
Topics: Adult; Alanine; Epinephrine; Glucagon; Glucose; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia | 1979 |
Glucose homeostasis in children with severe cyanotic congenital heart disease.
Topics: Alanine; Blood Glucose; Child, Preschool; Fasting; Glucagon; Glucose; Heart Defects, Congenital; Hom | 1979 |
Hypoglycemia in children.
Topics: Adult; Alanine; Blood Glucose; Child; Fasting; Glucagon; Glucocorticoids; Gluconeogenesis; Growth Ho | 1979 |
Insulin-induced hypoglycemia is not aggravated by somatostatin in insulin-dependent diabetes.
Topics: Alanine; Amines; Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucagon; Growth Horm | 1979 |
A contribution to the neurochemical basis of the pyrithioxin effect on the brain glucose utilisation during relative brain hypoglycaemia induced by anticipation stress.
Topics: Alanine; Ammonia; Animals; Blood Glucose; Brain; Ethanolamines; gamma-Aminobutyric Acid; Humans; Hyp | 1978 |
[Spontaneous hypoglycemia and chronic kidney insufficiency].
Topics: Adult; Alanine; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Kidney Fail | 1978 |
Reduced gluconeogenesis due to hyperinsulinism: hormonal and metabolic studies in an infant with hypoglycemia.
Topics: Alanine; Child, Preschool; Fatty Acids, Nonesterified; Glucagon; Gluconeogenesis; Glycerol; Humans; | 1978 |
Metabolic and hormonal effects of ethanol.
Topics: Alanine; Animals; Blood Glucose; Ethanol; Fatty Acids, Nonesterified; Glucagon; Glycerol; Hydrocorti | 1978 |
Effect of intravenous hydrocortisone administration on glucose homeostasis in small for gestational age infants.
Topics: Alanine; Blood Glucose; Female; Gluconeogenesis; Glucose; Homeostasis; Humans; Hydrocortisone; Hypog | 1979 |
Blunting of spontaneous and alanine-stimulated glucagon secretion in newborn infants of diabetic mothers.
Topics: Alanine; Blood Glucose; Female; Glucagon; Humans; Hypoglycemia; Infant, Newborn; Infant, Newborn, Di | 1979 |
The mechanism of hypoglycemia due to semistarvation in the rat.
Topics: Alanine; Animals; Blood Glucose; Disease Models, Animal; Energy Metabolism; Glucagon; Glucose; Glyce | 1976 |
Fasting-induced hypoglycemia in experimentally malnourished rats.
Topics: Adaptation, Physiological; Alanine; Aminobutyrates; Animals; Brain Chemistry; Disease Models, Animal | 1977 |
Correlation of blood and brain amino acids in hypoglycemic and normoglycemic rats.
Topics: Age Factors; Alanine; Amino Acids; Animals; Animals, Newborn; Blood Glucose; Brain; Glucose; Glutama | 1976 |
Infantile cataracts, Coats' disease, and ketotic hypoglycemia.
Topics: Acidosis; Alanine; Blood Glucose; Cataract; Cataract Extraction; Fasting; Female; Glaucoma; Humans; | 1976 |
The metabolic effects of glucagon infusion in normoglycaemic and hypoglycaemic small-for-gestational-age infants. II. Changes in plasma amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Blood Glucose; Citrulline; Glucagon; Gluconeogenesis; Glycine; | 1976 |
Acute renal failure: an important complication of cardiac surgery in infants.
Topics: Acute Kidney Injury; Alanine; Cardiac Surgical Procedures; Female; Heart Defects, Congenital; Humans | 1975 |
Hyperaminoacidemia due to the accumulation of gluconeogenic amino acid precursors in hypoglycemic small-for-gestational age infants.
Topics: Alanine; Amino Acids; Birth Weight; Female; Gestational Age; Gluconeogenesis; Glycine; Humans; Hypog | 1975 |
Counteraction of glucocorticoid--induced hyperglycaemia by hypoglycin.
Topics: Alanine; Animals; Cyclopropanes; Glucocorticoids; Gluconeogenesis; Hyperglycemia; Hypoglycemia; Hypo | 1975 |
Gluconeogenesis in infancy and childhood. II. Studies on the glucose production from alanine in three cases of persistent neonatal hypoglycaemia.
Topics: Alanine; Amino Acids; Blood Glucose; Female; Glucagon; Gluconeogenesis; Glycerol; Humans; Hypoglycem | 1976 |
Relationship between decrements in glucose level and metabolic response to hypoglycemia in absence of counterregulatory hormones in the conscious dog.
Topics: Adrenalectomy; Alanine; Animals; Blood Glucose; Dogs; Epinephrine; Fatty Acids, Nonesterified; Femal | 1992 |
Attenuated glucose recovery from hypoglycemia in the elderly.
Topics: 3-Hydroxybutyric Acid; Adult; Age Factors; Aged; Alanine; Analysis of Variance; Blood Glucose; Blood | 1992 |
Role of glucagon in countering hypoglycemia induced by insulin infusion in dogs.
Topics: Alanine; Animals; Blood Glucose; Dogs; Female; Glucagon; Gluconeogenesis; Glycerol; Glycogen; Hormon | 1991 |
Hypoinsulinemia is not critical to glucose recovery from hypoglycemia in humans.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Epinephrine; Fatty Acids, Nonesterified; Femal | 1991 |
Specificity of hypoglycaemia for cerebral malaria in children.
Topics: Alanine; Blood Glucose; Brain Diseases; C-Peptide; Child; Child, Preschool; Coma; Discriminant Analy | 1990 |
Failure of nocturnal hypoglycemia to cause daytime hyperglycemia in patients with IDDM.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; E | 1990 |
Hypoglycemia during diarrhea in childhood. Prevalence, pathophysiology, and outcome.
Topics: Adolescent; Alanine; Aspartate Aminotransferases; Bilirubin; Blood Glucose; C-Peptide; Child; Child, | 1990 |
Demonstration of a role for growth hormone in glucose counterregulation.
Topics: Adult; Alanine; C-Peptide; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Glycerol; Grow | 1989 |
Comparison of glucose counterregulation during short-term and prolonged hypoglycemia in normal humans.
Topics: Adult; Alanine; Blood Glucose; C-Peptide; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; | 1986 |
Relationship between changes in glucose production and gluconeogenesis during mild hypoglycemia in humans.
Topics: Adult; Alanine; Blood Glucose; C-Peptide; Female; Gluconeogenesis; Humans; Hypoglycemia; Insulin; Li | 1988 |
Stimulation of glucose production through hormone secretion and other mechanisms during insulin-induced hypoglycemia.
Topics: Alanine; Animals; Blood Glucose; Dogs; Epinephrine; Female; Glucagon; Gluconeogenesis; Glucose; Glyc | 1988 |
Glucoregulation during exercise: hypoglycemia is prevented by redundant glucoregulatory systems, sympathochromaffin activation, and changes in islet hormone secretion.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; C-Peptide; Chromaffin System; Epinephrine; Fat | 1986 |
[Changes in the alanine level in hypoglycemic states in children].
Topics: Alanine; Child; Child, Preschool; Female; Humans; Hyperinsulinism; Hypoglycemia; Infant; Male | 1987 |
Altered growth, hypoglycemia, hypoalaninemia, and ketonemia in the young rat: postnatal consequences of intrauterine growth retardation.
Topics: 3-Hydroxybutyric Acid; Alanine; Animals; Animals, Newborn; Body Weight; Brain; DNA; Female; Fetal Gr | 1985 |
Studies on the site of the block in gluconeogenesis causing severe hypoglycemia in intestinal ischemia shock in rats.
Topics: Adenosine Triphosphate; Alanine; Animals; Epinephrine; Female; Glucagon; Gluconeogenesis; Hypoglycem | 1985 |
Changes in carbohydrate substrates, amino acids and ammonia in the brain during insulin-induced hypoglycemia.
Topics: Alanine; Amino Acids; Ammonia; Animals; Blood Glucose; Carbohydrate Metabolism; Cerebral Cortex; Cit | 1974 |
"Ketotic hypoglycemia" due to hepatic fructose-1,6-diphosphatase deficiency: treatment with folic acid.
Topics: Acidosis; Alanine; Aldehyde-Lyases; Child, Preschool; Fasting; Female; Folic Acid; Fructose; Fructos | 1972 |
Thiamine-responsive lactice acidosis in a patient with deficient low-KM pyruvate carboxylase activity in liver.
Topics: Acidosis; Adrenocorticotropic Hormone; Alanine; Amino Acids; Diet Therapy; Female; Gluconeogenesis; | 1972 |
Response to 2-deoxy-D-glucose and to glucagon in "ketotic hypoglycemia" of childhood: evidence for epinephrine deficiency and altered alanine availability.
Topics: Adrenocorticotropic Hormone; Alanine; Blood Glucose; Child; Child, Preschool; Diseases in Twins; Epi | 1973 |
The intravenous L-alanine tolerance test as a means for investigating gluconeogenesis.
Topics: Alanine; Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Child; Child, Preschool; Drug Tolera | 1974 |
Glycemic response to 24-hour fast in normal children and children with ketotic hypoglycemia: II. Hormonal and metabolic changes.
Topics: Acidosis; Alanine; Amino Acids; Autoanalysis; Blood Glucose; Child; Child, Preschool; Fasting; Fatty | 1974 |
Hypoglycemia in compensated chronic renal insufficiency. Substrate limitation of gluconeogenesis.
Topics: Alanine; Carbon Radioisotopes; Diabetic Nephropathies; Female; Fluorometry; Glucagon; Gluconeogenesi | 1974 |
The metabolic effects of sodium dichloroacetate in the starved rat.
Topics: Acetates; Acetoacetates; Alanine; Animals; Blood Glucose; Chlorine; Gluconeogenesis; Glutamine; Hepa | 1974 |
Hypoglycemia and depressed hepatic gluconeogenesis during endotoxicosis in lead-sensitized rats.
Topics: Alanine; Animals; Blood Glucose; Endotoxins; Fructose; Gluconeogenesis; Hypoglycemia; Lactates; Lead | 1973 |
Depression of hepatic gluconeogenesis and the hypoglycemia of endotoxin shock.
Topics: Alanine; Animals; Blood Glucose; Carbon Radioisotopes; Depression, Chemical; Endotoxins; Fasting; Gl | 1974 |
Investigation of hepatic ATP and glucose 6-phosphate as indices of hypoglycin toxicity.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Animals; Blood Glucose; Cyclopropanes; Dose-Response R | 1973 |
Hypoglycemia and maple syrup urine disease: defective gluconeogenesis.
Topics: Alanine; Amino Acids; Chromatography; Diet Therapy; Female; Fructose; Glucagon; Gluconeogenesis; Glu | 1973 |
Effect of leucine on carbohydrate metabolism of the liver.
Topics: Alanine; Amino Acids; Animals; Blood Glucose; Carbohydrate Metabolism; Chlorpropamide; Drug Synergis | 1973 |
Rat brain and blood gluconeogenic metabolic changes in neonatal starvation.
Topics: Age Factors; Alanine; Amino Acids; Animals; Animals, Newborn; Brain; Female; Food Deprivation; Gluco | 1973 |
The apparent failure of L-carnitine to prevent the hypoglycaemia and hypothermia caused by hypoglycin or by pent-4-enoic acid in mice.
Topics: Alanine; Animals; Blood Glucose; Body Temperature; Carnitine; Cyclopropanes; Diet; Hypoglycemia; Hyp | 1973 |
Renal metabolism of amino acids and ammonia in fed and fasted pregnant sheep.
Topics: Acidosis; Alanine; Amino Acids; Ammonia; Animals; Arginine; Aspartic Acid; Catheterization; Citrulli | 1974 |
Ketotic hypoglycaemia due to hypoalaninaemia.
Topics: Acidosis; Alanine; Child; Gluconeogenesis; Humans; Hypoglycemia; Male; Metabolic Diseases; Syndrome | 1974 |
Incorporation of carbon from glucose into cerebral amino acids, proteins and lipids, and alterations during recovery from hypoglycaemia.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Blood Glucose; Carbon Isotopes; Cerebr | 1972 |
Amino acid metabolism during starvation in human pregnancy.
Topics: Adolescent; Adult; Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Blood Glucose; Female; Food | 1972 |
Hypoalaninemia: a concomitant of ketotic hypoglycemia.
Topics: Alanine; Blood Glucose; Child, Preschool; Deficiency Diseases; Female; Glucagon; Gluconeogenesis; Hu | 1972 |
[Disturbance of carbohydrate metabolism in the alcohol-fed rats].
Topics: Adipose Tissue; Alanine; Animals; Blood Glucose; Carbon Isotopes; Diaphragm; Ethanol; Glucose; Gluco | 1971 |
Carbohydrate metabolism in pregnancy. IX. Plasma levels of gluconeogenic fuels during fasting in the rat.
Topics: Alanine; Amino Acids; Animals; Carbohydrate Metabolism; Fasting; Female; Gluconeogenesis; Glutamates | 1971 |
Distribution of hypoglycin-A in the rat following acute intoxication.
Topics: Alanine; Animals; Cyclopropanes; Hypoglycemia; Plant Poisoning; Rats; Toxins, Biological | 1971 |
Hypoglycemia and developmental changes in free amino acids of rat brain.
Topics: Age Factors; Alanine; Amino Acids; Aminobutyrates; Animals; Brain; Glutamates; Glycine; Hypoglycemia | 1970 |
Glucose homeostasis in viral hepatitis.
Topics: Acute Disease; Adolescent; Adult; Alanine; Amino Acids; Biopsy; Blood Glucose; Dietary Carbohydrates | 1970 |
Regulatory effects of insulin and liver on brain glucose metabolism.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Autoanalysis; Blood Glucose; Brain; Carbon Isotopes | 1969 |
Effects of 5-methoxyindole-2-carboxylic acid on carbohydrate metabolism.
Topics: Acids; Alanine; Animals; Blood Glucose; Carbohydrate Metabolism; Carbon Isotopes; Diabetes Mellitus, | 1969 |
Chemical changes in the brain during insulin hypoglycaemia and recovery.
Topics: Acetylcholine; Alanine; Amino Acids; Aminobutyrates; Ammonia; Animals; Aspartic Acid; Brain; Brain C | 1965 |
Alcohol hypoglycemia. VI. Interrelationships between the formation of glyceride-glycerol and glucose from alanine by liver slices.
Topics: Alanine; Animals; Ethanol; Fatty Liver; Gluconeogenesis; Glycerides; Glycerol; Glycerophosphates; Hy | 1966 |
Studies of the hypoglycemic effect of D-amphetamine in aggregated mice.
Topics: Alanine; Animals; Antibody Formation; Behavior, Animal; Blood Glucose; Carbon Dioxide; Carbon Isotop | 1966 |