Page last updated: 2024-11-08

alanine and Hemolysis

alanine has been researched along with Hemolysis in 33 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.

Research Excerpts

ExcerptRelevanceReference
" Malondialdehyde (MDA), carbonyl content, alanine formation, and hemolysis were used as biomarkers of oxidative stress, and were determined in rabbit erythrocytes treated in vitro with benzo[a]pyrene or adriamycin."3.69Oxidation of erythrocyte protein and lipid, and hemolysis in rabbit red blood cells treated with benzo[a]pyrene or adriamycin. ( Lee, BM; Lee, SK, 1997)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199010 (30.30)18.7374
1990's5 (15.15)18.2507
2000's7 (21.21)29.6817
2010's8 (24.24)24.3611
2020's3 (9.09)2.80

Authors

AuthorsStudies
Noden, M1
Goodyear, J1
Taylor, SD1
Sepahi, M1
Ahangari Cohan, R1
Hadadian, S1
Norouzian, D1
Wu, J1
Qu, C1
Zhang, S1
Chen, W1
Wang, S1
Lopes, KS1
Campos, GAA1
Camargo, LC1
de Souza, ACB1
Ibituruna, BV1
Magalhães, ACM1
da Rocha, LF1
Garcia, AB1
Rodrigues, MC1
Ribeiro, DM1
Costa, MC1
López, MHM1
Nolli, LM1
Zamudio-Zuniga, F1
Possani, LD1
Schwartz, EF1
Mortari, MR1
Wan, Y1
Stanovych, A1
Gori, D1
Zirah, S1
Kouklovsky, C1
Alezra, V1
Taniguchi, M1
Takahashi, N1
Takayanagi, T1
Ikeda, A1
Ishiyama, Y1
Saitoh, E1
Kato, T1
Ochiai, A1
Tanaka, T1
Li, Y1
Bionda, N1
Yongye, A1
Geer, P1
Stawikowski, M1
Cudic, P1
Martinez, K1
Houghten, RA1
Li, W1
Tan, T1
Xu, W1
Xu, L1
Dong, N1
Ma, D1
Shan, A1
Perinelli, DR1
Cespi, M1
Casettari, L1
Vllasaliu, D1
Cangiotti, M1
Ottaviani, MF1
Giorgioni, G1
Bonacucina, G1
Palmieri, GF1
González, R1
Albericio, F1
Cascone, O1
Iannucci, NB1
Knox-Macaulay, HH1
Rehman, JU1
Al Zadjali, S1
Fawaz, NA1
Al Kindi, S1
Kojouharova, MS1
Gadjeva, MG1
Tsacheva, IG1
Zlatarova, A1
Roumenina, LT1
Tchorbadjieva, MI1
Atanasov, BP1
Waters, P1
Urban, BC1
Sim, RB1
Reid, KB1
Kishore, U1
Wessolowski, A1
Bienert, M1
Dathe, M1
Asthana, N1
Yadav, SP1
Ghosh, JK1
Yamada, K1
Shinoda, SS1
Oku, H1
Komagoe, K1
Katsu, T1
Katakai, R1
Robaszkiewicz, A1
Bartosz, G1
Soszyński, M1
Marti, HR1
Scherrer, R1
Piller, M1
Ockelford, PA1
Liang, AY1
Wells, RM1
Vissers, M1
Brennan, SO1
Williamson, D1
Carrell, RW1
Hirano, M1
Ohba, Y1
Imai, K1
Ino, T1
Morishita, Y1
Matsui, T1
Shimizu, S1
Sumi, H1
Yamamoto, K1
Miyaji, T1
Honig, GR1
Shamsuddin, M1
Zaizov, R1
Steinherz, M1
Solar, I1
Kirschmann, C1
Koyama, I2
Nakamori, K1
Nagahama, T1
Ogasawara, M2
Nemoto, M2
Lee, SK1
Lee, BM1
McLauchlin, J1
Yu, K1
Kang, S1
Park, N1
Shin, J1
Kim, Y1
Ito, Y1
Kawamura, I1
Kohda, C1
Baba, H1
Kimoto, T1
Watanabe, I1
Nomura, T1
Mitsuyama, M1
Nakamura, T1
Yoshida, T1
Dempsey, CE1
Bazzo, R1
Harvey, TS1
Syperek, I1
Boheim, G1
Campbell, ID1
King, GF1
Kuchel, PW1
Weiler, E3
Weiler, IJ1
Sprenger, R1
Dittrich, B1
Kolb, H2
Neef, L1
Peters, JE1
Haschen, RJ1
Rimon, A1
Sela, M1

Other Studies

33 other studies available for alanine and Hemolysis

ArticleYear
Effect of Lipid Length and Cationic Residues on the Antibacterial and Hemolytic Activities of Paenibacterin.
    ACS infectious diseases, 2022, 10-14, Volume: 8, Issue:10

    Topics: Alanine; Anti-Bacterial Agents; Escherichia coli; Hemolysis; Humans; Klebsiella pneumoniae; Lipopept

2022
Effect of glutamic acid elimination/substitution on the biological activities of S3 cationic amphiphilic peptides.
    Preparative biochemistry & biotechnology, 2020, Volume: 50, Issue:7

    Topics: Alanine; Animals; Antimicrobial Cationic Peptides; Antineoplastic Agents; Cell Line, Tumor; Circular

2020
The second N-terminal aromatic residue of the fungal defensin, blapersin, of Blastomyces percursus is essential for its antibacterial activity.
    Peptides, 2020, Volume: 133

    Topics: Alanine; Amino Acid Substitution; Anti-Bacterial Agents; Blastomyces; Defensins; Fungal Proteins; Gr

2020
Characterization of two peptides isolated from the venom of social wasp Chartergellus communis (Hymenoptera: Vespidae): Influence of multiple alanine residues and C-terminal amidation on biological effects.
    Peptides, 2017, Volume: 95

    Topics: Alanine; Amino Acid Sequence; Animals; Hemolysis; Humans; Oligopeptides; Peptide Fragments; Peptides

2017
β,γ-diamino acids as building blocks for new analogues of Gramicidin S: Synthesis and biological activity.
    European journal of medicinal chemistry, 2018, Apr-10, Volume: 149

    Topics: Alanine; Amino Acids, Diamino; Anti-Bacterial Agents; Gramicidin; Hemolysis; Protein Structure, Seco

2018
Effect of substituting arginine and lysine with alanine on antimicrobial activity and the mechanism of action of a cationic dodecapeptide (CL(14-25)), a partial sequence of cyanate lyase from rice.
    Biopolymers, 2014, Volume: 102, Issue:1

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Anti-Infective Agents; Arginine; Ben

2014
Dissociation of antimicrobial and hemolytic activities of gramicidin S through N-methylation modification.
    ChemMedChem, 2013, Volume: 8, Issue:11

    Topics: Alanine; Anti-Infective Agents; Bacteria; Gramicidin; Hemolysis; Magnetic Resonance Spectroscopy; Pr

2013
Rational design of mirror-like peptides with alanine regulation.
    Amino acids, 2016, Volume: 48, Issue:2

    Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Cell Line; Cel

2016
Correlation among chemical structure, surface properties and cytotoxicity of N-acyl alanine and serine surfactants.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2016, Volume: 109

    Topics: Alanine; Amino Acids; Caco-2 Cells; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Design; Electr

2016
Improved antimicrobial activity of h-lysozyme (107-115) by rational Ala substitution.
    Journal of peptide science : an official publication of the European Peptide Society, 2010, Volume: 16, Issue:8

    Topics: Alanine; Anti-Infective Agents; Escherichia coli; Hemolysis; Humans; Microbial Sensitivity Tests; Mu

2010
Idiopathic thrombocytopenic purpura and hypokalaemic dRTA with compensated haemolysis and striking acanthocytosis in a band 3 (SLC4A1/AE1) A858D homozygote.
    Annals of hematology, 2013, Volume: 92, Issue:4

    Topics: Abetalipoproteinemia; Acidosis, Renal Tubular; Adolescent; Alanine; Amino Acid Substitution; Anion E

2013
Mutational analyses of the recombinant globular regions of human C1q A, B, and C chains suggest an essential role for arginine and histidine residues in the C1q-IgG interaction.
    Journal of immunology (Baltimore, Md. : 1950), 2004, Apr-01, Volume: 172, Issue:7

    Topics: Alanine; Animals; Arginine; Complement C1 Inactivator Proteins; Complement C1q; DNA Mutational Analy

2004
Antimicrobial activity of arginine- and tryptophan-rich hexapeptides: the effects of aromatic clusters, D-amino acid substitution and cyclization.
    The journal of peptide research : official journal of the American Peptide Society, 2004, Volume: 64, Issue:4

    Topics: Alanine; Amino Acid Motifs; Anti-Infective Agents; Antimicrobial Cationic Peptides; Arginine; Bacill

2004
Dissection of antibacterial and toxic activity of melittin: a leucine zipper motif plays a crucial role in determining its hemolytic activity but not antibacterial activity.
    The Journal of biological chemistry, 2004, Dec-31, Volume: 279, Issue:53

    Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Anti-Bacterial Agents; Antimicrobial Cationic Pepti

2004
Synthesis of low-hemolytic antimicrobial dehydropeptides based on gramicidin s.
    Journal of medicinal chemistry, 2006, Dec-28, Volume: 49, Issue:26

    Topics: Alanine; Anti-Bacterial Agents; Circular Dichroism; Gram-Positive Bacteria; Gramicidin; Hemolysis; M

2006
Effect of N-chloroamino acids on the erythrocyte.
    Free radical research, 2008, Volume: 42, Issue:1

    Topics: Alanine; Amino Acids; Aspartic Acid; Chloramines; Dose-Response Relationship, Drug; Drug Stability;

2008
[Clinicohematologic effects of hemoglobin Altdorf (alpha 2 beta 2 135 Ala replaced by Pro)].
    Folia haematologica (Leipzig, Germany : 1928), 1980, Volume: 107, Issue:4

    Topics: Adolescent; Alanine; Child, Preschool; Erythrocytes; Female; Heinz Bodies; Hemoglobinopathies; Hemog

1980
Hemoglobin Volga, beta 27 (B9) Ala replaced by Asp: functional and clinical correlations of an unstable hemoglobin.
    Hemoglobin, 1980, Volume: 4, Issue:3-4

    Topics: Alanine; Aspartic Acid; Drug Stability; Hemoglobins, Abnormal; Hemolysis; Humans; Infant; Male; Poly

1980
Hb Toyoake: beta 142 (H20) Ala replaced by Pro. A new unstable hemoglobin with high oxygen affinity.
    Blood, 1981, Volume: 57, Issue:4

    Topics: Adult; Alanine; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel;

1981
Hemoglobin Petah Tikva (alpha 110 ala replaced by asp): a new unstable variant with alpha-thalassemia-like expression.
    Blood, 1981, Volume: 57, Issue:4

    Topics: Alanine; Aspartic Acid; Chemical Phenomena; Chemistry; Child, Preschool; Genetic Variation; Genotype

1981
The reactivity of taurine with hypochlorous acid and its application for eye drops.
    Advances in experimental medicine and biology, 1996, Volume: 403

    Topics: Alanine; Animals; beta-Alanine; Chlorine; Conjunctiva; Cornea; Dogs; Erythrocytes; Glycine; Hemolysi

1996
Oxidation of erythrocyte protein and lipid, and hemolysis in rabbit red blood cells treated with benzo[a]pyrene or adriamycin.
    Journal of toxicology and environmental health, 1997, Aug-29, Volume: 51, Issue:6

    Topics: Alanine; Animals; Antibiotics, Antineoplastic; Benzo(a)pyrene; Biomarkers; Carcinogens; Cells, Cultu

1997
The identification of Listeria species.
    International journal of food microbiology, 1997, Aug-19, Volume: 38, Issue:1

    Topics: Alanine; Carbohydrate Metabolism; Cell Movement; Hemolysis; Hydrolysis; Listeria; Reagent Kits, Diag

1997
Relationship between the tertiary structures of mastoparan B and its analogs and their lytic activities studied by NMR spectroscopy.
    The journal of peptide research : official journal of the American Peptide Society, 2000, Volume: 55, Issue:1

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Circular Dichroism; He

2000
Difference in cholesterol-binding and cytolytic activities between listeriolysin O and seeligeriolysin O: a possible role of alanine residue in tryptophan-rich undecapeptide.
    FEMS microbiology letters, 2001, Sep-25, Volume: 203, Issue:2

    Topics: Alanine; Animals; Bacterial Toxins; Cholesterol; Heat-Shock Proteins; Hemolysin Proteins; Hemolysis;

2001
The protective effect of taurine on the biomembrane against damage produced by the oxygen radical.
    Advances in experimental medicine and biology, 1992, Volume: 315

    Topics: Alanine; Amidines; Animals; Dogs; Drug Carriers; Erythrocyte Membrane; Free Radicals; Glucose; Hemol

1992
Contribution of proline-14 to the structure and actions of melittin.
    FEBS letters, 1991, Apr-09, Volume: 281, Issue:1-2

    Topics: Alanine; Amino Acid Sequence; Electric Conductivity; Hemolysis; Humans; Hydrogen Bonding; Lipid Bila

1991
Assimilation of alpha-glutamyl-peptides by human erythrocytes. A possible means of glutamate supply for glutathione synthesis.
    The Biochemical journal, 1985, May-01, Volume: 227, Issue:3

    Topics: Alanine; Animals; Biological Transport; Dipeptides; Erythrocytes; Glutamates; Glutamic Acid; Glutami

1985
Analysis of antibody populations to oligo-alanine determinants. L. An antibody assay by one-hit sensitization of red cells.
    European journal of immunology, 1971, Volume: 1, Issue:5

    Topics: Alanine; Animals; Antibodies; Antigen-Antibody Reactions; Cattle; Complement System Proteins; Epitop

1971
Analysis of antibody populations to oligo-alanine determinants. 3. The participation of subclasses IgG1 in the antibody response in inbred mice.
    Journal of immunology (Baltimore, Md. : 1950), 1973, Volume: 111, Issue:5

    Topics: Alanine; Animals; Antibodies; Antibody Formation; Antigen-Antibody Reactions; Ascitic Fluid; Cattle;

1973
Analysis of antibody populations to oligo-alanine determinants. IV. Functional similarity of variable regions of IgG1 and IgG2a antibodies.
    Journal of immunology (Baltimore, Md. : 1950), 1973, Volume: 111, Issue:5

    Topics: Absorption; Alanine; Animals; Antibodies; Antigen-Antibody Reactions; Antigens, Bacterial; Cattle; E

1973
[Alanine and leucine aminopeptidase in isolated human blood cells].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1973, Oct-01, Volume: 28, Issue:19

    Topics: Adult; Alanine; Aminopeptidases; Blood Cells; Blood Platelets; Erythrocytes; Female; Hemolysis; Huma

1973
Chemical modification of human erythrocytes by attachment of tyrosine and alanine peptides.
    Biochimica et biophysica acta, 1966, Aug-24, Volume: 124, Issue:2

    Topics: Alanine; Erythrocytes; Hemagglutination; Hemolysis; Humans; In Vitro Techniques; Peptides; Tyrosine

1966