alanine has been researched along with Hemoglobinopathies in 17 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Hemoglobinopathies: A group of inherited disorders characterized by structural alterations within the hemoglobin molecule.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The biosynthesis of two types of human fetal hemoglobin (Hb F), namely Hb F with G gamma chains having glycine in position 136 and Hb F with A gamma chains having alanine in position 136, was studied in blood samples and in cultures of erythroid precursors from blood of patients with different hemoglobinopathies." | 3.66 | The synthesis of fetal hemoglobin types in red blood cells and in BFU-E derived colonies from peripheral blood of patients with sickle cell anemia, beta+ - and delta beta-thalassemia, various forms of hereditary persistence of fetal hemoglobin, normal adu ( Efremov, GD; Gravely, ME; Harris, HF; Howard, JS; Huisman, TH; Reese, AL; Wilson, JB, 1979) |
| " In Greek double heterozygotes for beta-thalassemia and the hereditary persistence of fetal hemoglobin, fetal hemoglobin is increased above the level of hemoglobin F in simple heterozygotes and gamma-chains with glycine in position 136 become apparent." | 3.65 | Nature of fetal hemoglobin in the Greek type of hereditary persistence of fetal hemoglobin with and without concurrent beta-thalassemia. ( Apell, G; Bouver, N; Huisman, TH; Schroeder, WA; Shelton, JB; Shelton, JR; Stamatoyannopoulos, G, 1970) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (88.24) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marti, HR | 1 |
| Scherrer, R | 1 |
| Piller, M | 1 |
| Ferranti, P | 1 |
| Parlapiano, A | 1 |
| Malorni, A | 1 |
| Pucci, P | 1 |
| Marino, G | 1 |
| Cossu, G | 1 |
| Manca, L | 1 |
| Masala, B | 1 |
| Deutsch, S | 1 |
| Darbellay, R | 1 |
| Offord, R | 1 |
| Frutiger, A | 1 |
| Kister, J | 1 |
| Wajcman, H | 1 |
| Beris, P | 1 |
| Clegg, JB | 2 |
| Metaxatou-Mavromati, A | 1 |
| Kattamis, C | 1 |
| Sofroniadou, K | 1 |
| Wood, WG | 2 |
| Weatherall, DJ | 2 |
| Huisman, TH | 7 |
| Efremov, GD | 2 |
| Reese, AL | 1 |
| Howard, JS | 1 |
| Gravely, ME | 1 |
| Harris, HF | 1 |
| Wilson, JB | 2 |
| Merault, G | 1 |
| Keclard, L | 1 |
| Garin, J | 1 |
| Poyart, C | 1 |
| Blouquit, Y | 1 |
| Arous, N | 1 |
| Galacteros, F | 1 |
| Feingold, J | 1 |
| Rosa, J | 1 |
| Beutler, E | 1 |
| Lang, A | 1 |
| Lehmann, H | 2 |
| Boon, WH | 2 |
| Tsakok, FH | 1 |
| Schroeder, WA | 6 |
| Sukumaran, PK | 1 |
| Sadikario, A | 1 |
| Stojmirovic, E | 1 |
| Shelton, JR | 5 |
| Shelton, JB | 5 |
| Apell, G | 5 |
| Brodie, AR | 1 |
| Bouver, NG | 1 |
| Miller, A | 1 |
| Mann, JR | 1 |
| MacNeish, AS | 1 |
| Bannister, D | 1 |
| Wiltshire, BG | 1 |
| Clark, KG | 1 |
| Lorkin, PA | 1 |
| Blackwell, RQ | 1 |
| Liu, CS | 1 |
| Weng, MI | 1 |
| Dozy, AM | 1 |
| Boyd, EM | 1 |
| Adams, HR | 1 |
| Stamatoyannopoulos, G | 1 |
| Bouver, N | 1 |
17 other studies available for alanine and Hemoglobinopathies
| Article | Year |
|---|---|
[Clinicohematologic effects of hemoglobin Altdorf (alpha 2 beta 2 135 Ala replaced by Pro)].
Topics: Adolescent; Alanine; Child, Preschool; Erythrocytes; Female; Heinz Bodies; Hemoglobinopathies; Hemog | 1980 |
Hemoglobin Ozieri: a new alpha-chain variant (alpha 71(E20)Ala-->Val). Characterization using FAB- and electrospray-mass spectrometric techniques.
Topics: Alanine; Base Sequence; Fetal Blood; Globins; Hemoglobinopathies; Hemoglobins, Abnormal; Humans; Inf | 1993 |
Hb Iraq-Halabja beta10 (A7) Ala-->Val (GCC-->GTC): a new beta-chain silent variant in a family with multiple Hb disorders.
Topics: Adult; Alanine; Amino Acid Substitution; Child; Child, Preschool; Female; Genetic Variation; Genotyp | 1999 |
Occurrence of G gamma Hb F in Greek HPFH: analysis of heterozygotes and compound heterozygotes with beta thalassaemia.
Topics: Adult; Alanine; Erythrocyte Indices; Female; Fetal Hemoglobin; Globins; Glycine; Greece; Hemoglobin | 1979 |
The synthesis of fetal hemoglobin types in red blood cells and in BFU-E derived colonies from peripheral blood of patients with sickle cell anemia, beta+ - and delta beta-thalassemia, various forms of hereditary persistence of fetal hemoglobin, normal adu
Topics: Adult; Alanine; Anemia, Sickle Cell; Cells, Cultured; Chromatography, High Pressure Liquid; Clone Ce | 1979 |
Hemoglobin La Desirade alpha A2 beta 2 129 (H7) Ala----Val: a new unstable hemoglobin.
Topics: Alanine; Amino Acid Sequence; Black People; Chromatography, High Pressure Liquid; Hemoglobinopathies | 1986 |
Hemoglobin Duarte: (alpha2beta2 62(E6)Ala leads to Pro): a new unstable hemoglobin with increased oxygen affinity.
Topics: Adult; Alanine; Amino Acid Sequence; Amino Acids; Anemia, Hemolytic; Cell Survival; Chromium Radiois | 1974 |
A new structural haemoglobinopathy found in an Indian in Singapore--Hb Meerut alpha120 ALA leads to GLU.
Topics: Adult; Alanine; Anemia; Female; Glutamates; Hemoglobinopathies; Hemoglobins, Abnormal; Humans; India | 1974 |
A second type of hereditary persistence of foetal haemoglobin in India.
Topics: Adult; Alanine; Amino Acid Sequence; Child; Child, Preschool; Female; Fetal Hemoglobin; Globins; Gly | 1973 |
Chemical heterogeneity of foetal haemoglobin in the Lepore haemoglobinopathy.
Topics: Adolescent; Adult; Alanine; Amino Acid Sequence; Chemical Phenomena; Chemistry; Child; Chromatograph | 1974 |
Chemical heterogeneity of fetal hemoglobin in subjects with sickle cell anemia, homozygous Hb-C disease, SC disease, and various combinations of hemoglobin variants.
Topics: Adolescent; Adult; Aged; Aging; Alanine; Anemia, Sickle Cell; Child; Child, Preschool; Chromatograph | 1972 |
Delta-beta-thalassaemia in a Chinese family.
Topics: Adult; Alanine; Asian People; Black People; Carbon Isotopes; Child; Child, Preschool; Chromatography | 1972 |
Haemoglobin Denmark Hill 95 (G2) Pro-Ala, a variant with unusual electrophoretic and oxygen-binding properties.
Topics: Adult; Alanine; Amino Acid Sequence; Amino Acids; Electrophoresis, Paper; Electrophoresis, Starch Ge | 1972 |
Hemoglobin J Singapore: alpha 78 Asn--Asp; alpha 79 Ala--Gly.
Topics: Adult; Alanine; Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Chemical Phenomena; Che | 1972 |
Evidence for multiple structural genes for the gamma-chain of human fetal hemoglobin in hereditary persistence of fetal hemoglobin.
Topics: Adolescent; Adult; Aged; Alanine; Child; Child, Preschool; Erythrocyte Count; Female; Fetal Hemoglob | 1969 |
A possible subclass of the hereditary persistence of fetal hemoglobin.
Topics: Alanine; Amino Acid Sequence; Blood; Blood Protein Electrophoresis; Chromatography; Dextrans; Erythr | 1970 |
Nature of fetal hemoglobin in the Greek type of hereditary persistence of fetal hemoglobin with and without concurrent beta-thalassemia.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Chromatography, Paper; Fetal Hemoglobin; Glycine; Hem | 1970 |