Page last updated: 2024-11-08

alanine and HIV-Associated Lipodystrophy Syndrome

alanine has been researched along with HIV-Associated Lipodystrophy Syndrome in 3 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

HIV-Associated Lipodystrophy Syndrome: Defective metabolism leading to fat maldistribution in patients infected with HIV. The etiology appears to be multifactorial and probably involves some combination of infection-induced alterations in metabolism, direct effects of antiretroviral therapy, and patient-related factors.

Research Excerpts

ExcerptRelevanceReference
" The prehepatic insulin secretion rate was estimated by deconvolution of C-peptide concentrations, and insulin sensitivity (SIRd) was estimated by the glucose clamp technique."3.73Glucose-stimulated prehepatic insulin secretion is associated with circulating alanine, triglyceride, glucagon, lactate and TNF-alpha in patients with HIV-lipodystrophy. ( Andersen, O; Deacon, CF; Dela, F; Haugaard, SB; Holst, JJ; Iversen, J; Madsbad, S; Pedersen, SB, 2006)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Haugaard, SB3
Andersen, O3
Storgaard, H2
Dela, F3
Holst, JJ3
Iversen, J3
Nielsen, JO1
Madsbad, S3
Fenger, M1
Pedersen, SB1
Deacon, CF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Low-Dose Human Growth Hormone Therapy in HIV Infected Patients on Highly Active Antiretroviral Therapy (HAART)[NCT00119769]Phase 446 participants (Actual)Interventional2005-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for alanine and HIV-Associated Lipodystrophy Syndrome

ArticleYear
Insulin secretion in lipodystrophic HIV-infected patients is associated with high levels of nonglucose secretagogues and insulin resistance of beta-cells.
    American journal of physiology. Endocrinology and metabolism, 2004, Volume: 287, Issue:4

    Topics: Adipose Tissue; Adult; Alanine; Anthropometry; Blood Glucose; Body Composition; Body Mass Index; C-P

2004

Other Studies

2 other studies available for alanine and HIV-Associated Lipodystrophy Syndrome

ArticleYear
Defective glucose and lipid metabolism in human immunodeficiency virus-infected patients with lipodystrophy involve liver, muscle tissue and pancreatic beta-cells.
    European journal of endocrinology, 2005, Volume: 152, Issue:1

    Topics: Adult; Alanine; Antiretroviral Therapy, Highly Active; Blood Glucose; Body Composition; Cholesterol,

2005
Glucose-stimulated prehepatic insulin secretion is associated with circulating alanine, triglyceride, glucagon, lactate and TNF-alpha in patients with HIV-lipodystrophy.
    HIV medicine, 2006, Volume: 7, Issue:3

    Topics: Adult; Alanine; C-Peptide; Case-Control Studies; Glucagon; Glucose; Glucose Clamp Technique; HIV-1;

2006