alanine has been researched along with Graves Disease in 7 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Graves Disease: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).
| Excerpt | Relevance | Reference |
|---|---|---|
| " We studied the urea-nitrogen synthesis rate (UNSR) and the kinetics of the process of hepatic amino-nitrogen to urea-nitrogen conversion in response to constant alanine infusion (ie, the functional hepatic nitrogen clearance [FHNC]) in five hyperthyroid female patients before and after the achievement of a stable euthyroid status." | 7.69 | Hepatic conversion of amino-nitrogen to urea in thyroid diseases. II. A study in hyperthyroid patients. ( Bianchi, GP; Fabbri, A; Giovanelli, P; Lodi, A; Marchesini, G; Motta, E; Urbini, D, 1994) |
| "Patients with IDDM also had significantly more Ala alleles as homozygotes (19%) or heterozygotes (50%; P = 0." | 5.30 | CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and to type 1 diabetes mellitus. ( Badenhoop, K; Braun, J; Donner, H; Finke, R; Herwig, J; Rau, H; Siegmund, T; Usadel, KH; Walfish, PG, 1997) |
| " We studied the urea-nitrogen synthesis rate (UNSR) and the kinetics of the process of hepatic amino-nitrogen to urea-nitrogen conversion in response to constant alanine infusion (ie, the functional hepatic nitrogen clearance [FHNC]) in five hyperthyroid female patients before and after the achievement of a stable euthyroid status." | 3.69 | Hepatic conversion of amino-nitrogen to urea in thyroid diseases. II. A study in hyperthyroid patients. ( Bianchi, GP; Fabbri, A; Giovanelli, P; Lodi, A; Marchesini, G; Motta, E; Urbini, D, 1994) |
| "Patients with IDDM also had significantly more Ala alleles as homozygotes (19%) or heterozygotes (50%; P = 0." | 1.30 | CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and to type 1 diabetes mellitus. ( Badenhoop, K; Braun, J; Donner, H; Finke, R; Herwig, J; Rau, H; Siegmund, T; Usadel, KH; Walfish, PG, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grineva, E | 1 |
| Babenko, A | 1 |
| Vahrameeva, N | 1 |
| Bogdanova, M | 1 |
| Kostareva, A | 1 |
| Popcova, D | 1 |
| Larionova, V | 1 |
| Bresson, D | 1 |
| Cerutti, M | 1 |
| Devauchelle, G | 1 |
| Pugnière, M | 1 |
| Roquet, F | 1 |
| Bes, C | 1 |
| Bossard, C | 1 |
| Chardès, T | 1 |
| Péraldi-Roux, S | 1 |
| Marchesini, G | 1 |
| Fabbri, A | 1 |
| Bianchi, GP | 1 |
| Motta, E | 1 |
| Giovanelli, P | 1 |
| Urbini, D | 1 |
| Lodi, A | 1 |
| Donner, H | 1 |
| Rau, H | 1 |
| Walfish, PG | 1 |
| Braun, J | 1 |
| Siegmund, T | 1 |
| Finke, R | 1 |
| Herwig, J | 1 |
| Usadel, KH | 1 |
| Badenhoop, K | 1 |
| Heward, JM | 1 |
| Allahabadia, A | 1 |
| Armitage, M | 1 |
| Hattersley, A | 1 |
| Dodson, PM | 1 |
| Macleod, K | 1 |
| Carr-Smith, J | 1 |
| Daykin, J | 1 |
| Daly, A | 1 |
| Sheppard, MC | 1 |
| Holder, RL | 1 |
| Barnett, AH | 1 |
| Franklyn, JA | 1 |
| Gough, SC | 1 |
| Kosugi, S | 2 |
| Okajima, F | 1 |
| Ban, T | 2 |
| Hidaka, A | 1 |
| Shenker, A | 1 |
| Kohn, LD | 2 |
| Akamizu, T | 1 |
7 other studies available for alanine and Graves Disease
| Article | Year |
|---|---|
Type 2 deiodinase Thr92Ala polymorphism impact on clinical course and myocardial remodeling in patients with Graves' disease.
Topics: Adult; Alanine; Echocardiography; Female; Gene Frequency; Genetic Predisposition to Disease; Genotyp | 2009 |
Localization of the discontinuous immunodominant region recognized by human anti-thyroperoxidase autoantibodies in autoimmune thyroid diseases.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Antibodies; Antibodies, Monoclonal; Autoan | 2003 |
Hepatic conversion of amino-nitrogen to urea in thyroid diseases. II. A study in hyperthyroid patients.
Topics: Adult; Aged; Alanine; Amino Acids; Female; Graves Disease; Humans; Hyperthyroidism; Liver; Middle Ag | 1994 |
CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and to type 1 diabetes mellitus.
Topics: Abatacept; Adolescent; Adult; Alanine; Alleles; Antigens, CD; Antigens, Differentiation; Child; Chil | 1997 |
The development of Graves' disease and the CTLA-4 gene on chromosome 2q33.
Topics: Abatacept; Alanine; Alleles; Antigens, CD; Antigens, Differentiation; Case-Control Studies; Chromoso | 1999 |
Mutation of alanine 623 in the third cytoplasmic loop of the rat thyrotropin (TSH) receptor results in a loss in the phosphoinositide but not cAMP signal induced by TSH and receptor autoantibodies.
Topics: Alanine; Amino Acid Sequence; Animals; Autoantibodies; Binding, Competitive; Cell Line; Cholera Toxi | 1992 |
Identification of separate determinants on the thyrotropin receptor reactive with Graves' thyroid-stimulating antibodies and with thyroid-stimulating blocking antibodies in idiopathic myxedema: these determinants have no homologous sequence on gonadotropi
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Autoantibodies; Binding Sites; Binding, Competiti | 1992 |