Page last updated: 2024-11-08

alanine and Granulocytic Leukemia

alanine has been researched along with Granulocytic Leukemia in 9 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
"In a serine-deficient medium, cells from humangt chronic granulocytic leukemia and normal human bone marrow exhibited a marked inhibition of incorporation of-radioactive precursors of DNA, RNA, and protein into an acid insoluble cell fraction."3.65Serine requirement in leukemic and normal blood cells. ( Faulcon, FM; Lee, WH; Regan, JD; Takeda, S; Vodopick, N, 1969)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19906 (66.67)18.7374
1990's2 (22.22)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahmed, N1
Weidemann, MJ1
Pasche, B1
Luo, Y1
Rao, PH1
Nimer, SD1
Dmitrovsky, E1
Caron, P1
Luzzatto, L1
Offit, K1
Cordon-Cardo, C1
Renault, B1
Satagopan, JM1
Murty, VV1
Massagué, J1
Behre, G1
Singh, SM1
Liu, H1
Bortolin, LT1
Christopeit, M1
Radomska, HS1
Rangatia, J1
Hiddemann, W1
Friedman, AD1
Tenen, DG1
Desser, H1
Höcker, P2
Weiser, M2
Schuh, H1
Pittermann, E1
Stacher, A2
Armstrong, CA1
Klostergaard, J1
Granger, GA1
Maurer, HS1
Vida, LN1
Honig, GR1
Regan, JD1
Vodopick, N1
Takeda, S1
Lee, WH1
Faulcon, FM1
Wilson, WL1
Hurley, JD1
Mrazek, RG1

Other Studies

9 other studies available for alanine and Granulocytic Leukemia

ArticleYear
Biochemical effect of three different inhibitors of purine/pyrimidine metabolism on differentiation in HL60 cells.
    Leukemia research, 1995, Volume: 19, Issue:4

    Topics: Alanine; Cell Differentiation; Cell Division; Formates; Hematopoiesis; Humans; Hypoxanthine; Hypoxan

1995
Type I transforming growth factor beta receptor maps to 9q22 and exhibits a polymorphism and a rare variant within a polyalanine tract.
    Cancer research, 1998, Jul-01, Volume: 58, Issue:13

    Topics: Acute Disease; Alanine; Amino Acid Sequence; Blood Donors; Chromosome Mapping; Chromosomes, Human, P

1998
Ras signaling enhances the activity of C/EBP alpha to induce granulocytic differentiation by phosphorylation of serine 248.
    The Journal of biological chemistry, 2002, Jul-19, Volume: 277, Issue:29

    Topics: Acute Disease; Alanine; Amino Acid Substitution; CCAAT-Enhancer-Binding Protein-alpha; Cell Differen

2002
[Amino acids and vitamin B 12 in myeloid leukemia].
    MMW, Munchener medizinische Wochenschrift, 1976, Nov-12, Volume: 118, Issue:46

    Topics: Alanine; Alkylating Agents; Amino Acids; Gluconeogenesis; Humans; Isoleucine; Leukemia, Myeloid; Vit

1976
Isolation and initial characterization of tumoricidal monokine(s) from the human monocytic leukemia cell line THP-1.
    Journal of the National Cancer Institute, 1985, Volume: 74, Issue:1

    Topics: Alanine; Catalase; Cell Line; Cloning, Molecular; Cytotoxicity, Immunologic; Electrophoresis, Polyac

1985
Similarities of the erythrocytes in juvenile chronic myelogenous leukemia to fetal erythrocytes.
    Blood, 1972, Volume: 39, Issue:6

    Topics: Alanine; Blood Protein Electrophoresis; Bone Marrow Examination; Child, Preschool; Chromatography; D

1972
[Amino acid concentration in plasma and blood cells during coli-L-asparaginase therapy].
    Blut, 1972, Volume: 25, Issue:1

    Topics: Alanine; Amino Acids; Asparaginase; Asparagine; Autoanalysis; Erythrocytes; Glutamates; Humans; Leuk

1972
Serine requirement in leukemic and normal blood cells.
    Science (New York, N.Y.), 1969, Mar-28, Volume: 163, Issue:3874

    Topics: Alanine; Asparagine; Aspartic Acid; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Culture Media;

1969
Phase II study of alanine mustard (NSC-17663).
    Cancer chemotherapy reports, 1970, Volume: 54, Issue:5

    Topics: Alanine; Blood Cell Count; Bone Marrow; Humans; Leukemia, Myeloid; Mustard Compounds; Nausea; Thromb

1970