Page last updated: 2024-11-08

alanine and Gastrointestinal Hemorrhage

alanine has been researched along with Gastrointestinal Hemorrhage in 16 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.

Research Excerpts

ExcerptRelevanceReference
"Aspirin may reduce the risk of chronic hepatitis B (CHB)-related hepatocellular carcinoma (HCC) in patients receiving antiviral treatment."8.02Aspirin Reduces the Incidence of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B Receiving Oral Nucleos(t)ide Analog. ( Chan, HL; Hui, VW; Lui, GC; Tse, YK; Wong, GL; Wong, VW; Yip, TC, 2021)
"Aspirin may reduce the risk of chronic hepatitis B (CHB)-related hepatocellular carcinoma (HCC) in patients receiving antiviral treatment."4.02Aspirin Reduces the Incidence of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B Receiving Oral Nucleos(t)ide Analog. ( Chan, HL; Hui, VW; Lui, GC; Tse, YK; Wong, GL; Wong, VW; Yip, TC, 2021)
"Intestinal ulceration and bleeding were induced in Wistar rats by oral administration of naproxen."3.81Hydrogen sulphide protects against NSAID-enteropathy through modulation of bile and the microbiota. ( Bercik, P; Blackler, RW; Manko, A; Motta, JP; Surette, MG; Wallace, JL; Workentine, M, 2015)
"Coronary artery disease and co-use of thienopyridine were associated with SBB in NSAIDs users."3.81Risk factors for small bowel bleeding in chronic nonsteroidal anti-inflammatory drug users. ( Cho, KM; Choi, SK; Chung, JO; Jun, CH; Kim, BS; Kim, HS; Kim, TJ; Park, CH; Park, SY; Rew, JS; Son, DJ, 2015)
" The grade of gastric mucosal injuries was evaluated by esophagogastroduodenoscopy before and after dosing (on day 0 and day 14), and the grade of gastric mucosal injury was assessed according to the modified Lanza score."2.79A randomized, double-blind, placebo-controlled study of rebamipide for gastric mucosal injury taking aspirin with or without clopidogrel. ( Fukui, H; Hida, N; Hori, K; Miwa, H; Nakamura, S; Ogawa, T; Ohda, Y; Okugawa, T; Oshima, T; Tomita, T; Tozawa, K; Watari, J, 2014)
"Pretreatment with omeprazole (30 mg/kg s."1.30Influence of rebamipide on indometacin-induced gastric hemorrhage in rats under restraint stress. ( Arakawa, T; Higuchi, K; Kobayashi, K; Kuroki, T; Takaishi, O; Yamasaki, K, 1999)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19903 (18.75)18.7374
1990's3 (18.75)18.2507
2000's2 (12.50)29.6817
2010's7 (43.75)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Kim, TJ2
Kim, ER1
Hong, SN1
Kim, YH1
Lee, YC1
Kim, HS2
Kim, K1
Chang, DK1
Nagai, N1
Sakamoto, R1
Yamamoto, S1
Deguchi, S1
Otake, H1
Tanino, T1
Hui, VW1
Yip, TC1
Wong, VW1
Tse, YK1
Chan, HL1
Lui, GC1
Wong, GL1
Tozawa, K1
Oshima, T1
Okugawa, T1
Ogawa, T1
Ohda, Y1
Tomita, T1
Hida, N1
Fukui, H1
Hori, K1
Watari, J1
Nakamura, S1
Miwa, H1
Sugimoto, M1
Uotani, T1
Furuta, T1
Blackler, RW1
Motta, JP1
Manko, A1
Workentine, M1
Bercik, P1
Surette, MG1
Wallace, JL1
Takeuchi, K1
Takayama, S1
Hashimoto, E1
Itayama, M1
Amagase, K1
Izuhara, C1
Cho, KM1
Park, SY1
Chung, JO1
Jun, CH1
Son, DJ1
Kim, BS1
Park, CH1
Choi, SK1
Rew, JS1
BORRELLI, F1
DELLORUSSO, R1
Atar, S1
Cannon, CP1
Murphy, SA1
Rosanio, S1
Uretsky, BF1
Birnbaum, Y1
Niwa, Y1
Nakamura, M1
Omiya, N1
Itoh, A1
Hirooka, Y1
Goto, H1
Foster, KJ1
Alberti, KG1
Binder, C1
Holdstock, G1
Karran, SJ1
Smith, CL1
Talbot, S1
Turnell, DC1
Sakurai, K1
Yamasaki, K2
Huh, K1
Kwon, TH1
Kim, SK1
Kim, JS1
Shin, US1
Arakawa, T1
Takaishi, O1
Higuchi, K1
Kobayashi, K1
Kuroki, T1
van Berlo, CL1
van de Bogaard, AE1
van der Heijden, MA1
van Eijk, HM1
Janssen, MA1
Bost, MC1
Soeters, PB1

Trials

1 trial available for alanine and Gastrointestinal Hemorrhage

ArticleYear
A randomized, double-blind, placebo-controlled study of rebamipide for gastric mucosal injury taking aspirin with or without clopidogrel.
    Digestive diseases and sciences, 2014, Volume: 59, Issue:8

    Topics: Adult; Alanine; Anti-Ulcer Agents; Aspirin; Clopidogrel; Double-Blind Method; Gastric Mucosa; Gastro

2014

Other Studies

15 other studies available for alanine and Gastrointestinal Hemorrhage

ArticleYear
Effectiveness of acid suppressants and other mucoprotective agents in reducing the risk of occult gastrointestinal bleeding in nonsteroidal anti-inflammatory drug users.
    Scientific reports, 2019, 08-12, Volume: 9, Issue:1

    Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cohort Studies

2019
Solid Nanocrystals of Rebamipide Promote Recovery from Indomethacin-Induced Gastrointestinal Bleeding.
    International journal of molecular sciences, 2019, Oct-09, Volume: 20, Issue:20

    Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Gastrointestinal Hemorrhage; Indomethacin

2019
Aspirin Reduces the Incidence of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B Receiving Oral Nucleos(t)ide Analog.
    Clinical and translational gastroenterology, 2021, 03-23, Volume: 12, Issue:3

    Topics: Adult; Aged; Alanine; Antiviral Agents; Aspirin; Carcinoma, Hepatocellular; Drug Therapy, Combinatio

2021
Does rebamipide prevent gastric mucosal injury in patients taking aspirin and clopidogrel?
    Digestive diseases and sciences, 2014, Volume: 59, Issue:8

    Topics: Alanine; Anti-Ulcer Agents; Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Male; Platele

2014
Hydrogen sulphide protects against NSAID-enteropathy through modulation of bile and the microbiota.
    British journal of pharmacology, 2015, Volume: 172, Issue:4

    Topics: Alanine; Allyl Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile; Cell Line; Cycloox

2015
Effect of rebamipide on gastric bleeding and ulcerogenic responses induced by aspirin plus clopidogrel under stimulation of acid secretion in rats.
    Journal of gastroenterology and hepatology, 2014, Volume: 29 Suppl 4

    Topics: Alanine; Animals; Anti-Ulcer Agents; Aspirin; Clopidogrel; Disease Models, Animal; Gastric Acid; Gas

2014
Risk factors for small bowel bleeding in chronic nonsteroidal anti-inflammatory drug users.
    Journal of digestive diseases, 2015, Volume: 16, Issue:9

    Topics: Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Capsule Endoscopy; Corona

2015
[PLASMA ENZYME BEHAVIOR (ASPARTIC AND ALANINE KETOGLUTARIC TRANSAMINASES) IN HEMORRHAGIC SUBJECTS].
    Rassegna internazionale di clinica e terapia, 1963, Dec-15, Volume: 43

    Topics: Alanine; Alanine Transaminase; Aspartate Aminotransferases; Blood Chemical Analysis; Clinical Enzyme

1963
Statins are associated with lower risk of gastrointestinal bleeding in patients with unstable coronary syndromes: analysis of the Orbofiban in Patients with Unstable coronary Syndromes-Thrombolysis In Myocardial Infarction 16 (OPUS-TIMI 16) trial.
    American heart journal, 2006, Volume: 151, Issue:5

    Topics: Acute Disease; Administration, Oral; Aged; Alanine; Anticoagulants; Aspirin; Coronary Disease; Femal

2006
Ileal cancer and erosions in the small intestine revealed by capsule endoscopy.
    Endoscopy, 2007, Volume: 39 Suppl 1

    Topics: Adenocarcinoma; Adenoma; Aged, 80 and over; Alanine; Anti-Ulcer Agents; Capsule Endoscopy; Colonic N

2007
The metabolic effects of moderately severe upper gastrointestinal haemorrhage in man.
    Postgraduate medical journal, 1982, Volume: 58, Issue:675

    Topics: Alanine; Female; Gastrointestinal Hemorrhage; Glucose; Glycerol; Humans; Hydrocortisone; Insulin; La

1982
Protective effect of rebamipide against hydrogen peroxide-induced hemorrhagic mucosal lesions in rat stomach.
    Japanese journal of pharmacology, 1994, Volume: 64, Issue:4

    Topics: Alanine; Animals; Gastric Mucosa; Gastrointestinal Hemorrhage; Glutathione; Glutathione Peroxidase;

1994
Therapeutic effect of rebamipide on ammonia-induced gastric mucosal hemorrhagic lesion in rats.
    Archives of pharmacal research, 1998, Volume: 21, Issue:1

    Topics: Alanine; Ammonia; Animals; Anti-Ulcer Agents; Enzyme Inhibitors; Gastric Mucosa; Gastrointestinal He

1998
Influence of rebamipide on indometacin-induced gastric hemorrhage in rats under restraint stress.
    Arzneimittel-Forschung, 1999, Volume: 49, Issue:4

    Topics: Acute Disease; Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Catalas

1999
Is increased ammonia liberation after bleeding in the digestive tract the consequence of complete absence of isoleucine in hemoglobin? A study in pigs.
    Hepatology (Baltimore, Md.), 1989, Volume: 10, Issue:3

    Topics: Alanine; Ammonia; Animals; Blood Flow Velocity; Female; Gastrointestinal Hemorrhage; Glutamine; Hemo

1989