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alanine and Fatty Liver

alanine has been researched along with Fatty Liver in 13 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Fatty Liver: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.

Research Excerpts

ExcerptRelevanceReference
" In addition, increased hepatic microvasculatures compliance-related improved buffering effect of portal vein to acute mannitol infusion was associated with decreased circulating nitric oxide and aldosterone, plasma volume expansion (dye dilution method), splanchnic blood pooling ((99 m) Tc-RBC SPECT/PET/CT scans), peripheral hypotension, portal hypertension and ascites in brivanib and sorafenib-treated NASH-cirrhotic rats."3.80Anti-VEGFR agents ameliorate hepatic venous dysregulation/microcirculatory dysfunction, splanchnic venous pooling and ascites of NASH-cirrhotic rat. ( Hsieh, YC; Huang, YT; Lee, FY; Lee, KC; Lee, PC; Lee, WP; Lin, HC; Liu, RS; Tan, TW; Yang, YY; Yeh, YC, 2014)
"Rats were treated with a hepatotoxin thioacetamide (TAA) and examined 21 days later, when they showed moderate fatty metamorphosis of the liver and morphological changes in brain indicative of excitotoxic neuronal damage, but no evident biochemical or neurophysiological symptoms of hepatic encephalopathy (HE)."3.70Changes in the extracellular profiles of neuroactive amino acids in the rat striatum at the asymptomatic stage of hepatic failure. ( Albrecht, J; Borkowska, HD; Gadamski, R; Hilgier, W; Oja, SS; Saransaari, P; Walski, M; Zielińska, M, 1999)
"In all, 32 subjects (11 patients with nonalcoholic steatohepatitis [NASH], 15 with simple steatosis [SS], and six healthy controls) were studied."1.46Hepatic Alanine Differentiates Nonalcoholic Steatohepatitis From Simple Steatosis in Humans and Mice: A Proton MR Spectroscopy Study With Long Echo Time. ( Cho, EY; Choi, KH; Jeong, YY; Jun, CH; Jun, HY; Kim, KJ; Kim, TH; Lee, MS; Lee, YH; Yoon, KH; Yun, KJ, 2017)
"Histidine or carnosine treatments significantly improved insulin sensitivity and attenuated hyper-insulinemia (P<0."1.37Histidine and carnosine alleviated hepatic steatosis in mice consumed high saturated fat diet. ( Chao, CY; Mong, MC; Yin, MC, 2011)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's1 (7.69)18.2507
2000's1 (7.69)29.6817
2010's5 (38.46)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Bae, EJ1
Choi, WG1
Pagire, HS1
Pagire, SH1
Parameswaran, S1
Choi, JH1
Yoon, J1
Choi, WI1
Lee, JH1
Song, JS1
Bae, MA1
Kim, M1
Jeon, JH1
Lee, IK1
Kim, H1
Ahn, JH1
Schmilovitz-Weiss, H1
Gingold-Belfer, R1
Grossman, A1
Issa, N1
Boltin, D1
Beloosesky, Y1
Morag Koren, N1
Meyerovitch, J1
Weiss, A1
Yang, YY1
Liu, RS1
Lee, PC1
Yeh, YC1
Huang, YT1
Lee, WP1
Lee, KC1
Hsieh, YC1
Lee, FY1
Tan, TW1
Lin, HC1
Kim, TH1
Jun, HY1
Kim, KJ1
Lee, YH1
Lee, MS1
Choi, KH1
Yun, KJ1
Jeong, YY1
Jun, CH1
Cho, EY1
Yoon, KH1
Peng, X1
Zhang, L1
Wang, Q1
Cui, X1
Rey, JW1
Noetel, A1
Hardt, A1
Canbay, A1
Alakus, H1
Zur Hausen, A1
Dienes, HP1
Drebber, U1
Odenthal, M1
Mong, MC1
Chao, CY1
Yin, MC1
Hilgier, W1
Zielińska, M1
Borkowska, HD1
Gadamski, R1
Walski, M1
Oja, SS1
Saransaari, P1
Albrecht, J1
Bannister, DW1
Evans, AJ1
Whitehead, CC1
Whitehead, RG1
Coward, WA1
Lunn, PG1
Henley, KS1
Laughrey, EG1
Clancy, PE1
Sherwin, R1
Joshi, P1
Hendler, R1
Felig, P1
Conn, HO1
Sandler, R1
Freinkel, N1

Other Studies

13 other studies available for alanine and Fatty Liver

ArticleYear
Peripheral Selective Oxadiazolylphenyl Alanine Derivatives as Tryptophan Hydroxylase 1 Inhibitors for Obesity and Fatty Liver Disease.
    Journal of medicinal chemistry, 2021, 01-28, Volume: 64, Issue:2

    Topics: Adiposity; Alanine; Animals; Anti-Obesity Agents; Diet, High-Fat; Energy Metabolism; Enzyme Inhibito

2021
Lowering the upper limit of serum alanine aminotransferase levels may reveal significant liver disease in the elderly.
    PloS one, 2019, Volume: 14, Issue:4

    Topics: Aged; Alanine; Alanine Transaminase; Aspartate Aminotransferases; Fatty Liver; Female; Fibrosis; Ger

2019
Anti-VEGFR agents ameliorate hepatic venous dysregulation/microcirculatory dysfunction, splanchnic venous pooling and ascites of NASH-cirrhotic rat.
    Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34, Issue:4

    Topics: Alanine; Animals; Ascites; Cytokines; DNA Primers; Fatty Liver; Fibroblast Growth Factors; Microcirc

2014
Hepatic Alanine Differentiates Nonalcoholic Steatohepatitis From Simple Steatosis in Humans and Mice: A Proton MR Spectroscopy Study With Long Echo Time.
    Journal of magnetic resonance imaging : JMRI, 2017, Volume: 46, Issue:5

    Topics: Adult; Alanine; Animals; Area Under Curve; Biopsy; Case-Control Studies; Fatty Liver; Female; Hepato

2017
[Study on the relationship between FABP2 Ala54Thr polymorphism and the risk of non-alcoholic fatty liver diseases].
    Wei sheng yan jiu = Journal of hygiene research, 2009, Volume: 38, Issue:4

    Topics: Adult; Aged; Alanine; Amino Acid Substitution; Case-Control Studies; Fatty Acid-Binding Proteins; Fa

2009
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ2 in patients with fatty liver diseases.
    World journal of gastroenterology, 2010, Dec-14, Volume: 16, Issue:46

    Topics: Alanine; Biopsy; Fatty Liver; Humans; Polymorphism, Genetic; PPAR gamma; Proline

2010
Histidine and carnosine alleviated hepatic steatosis in mice consumed high saturated fat diet.
    European journal of pharmacology, 2011, Feb-25, Volume: 653, Issue:1-3

    Topics: Adipose Tissue; Alanine; Animals; Carnosine; Dietary Fats; Fatty Liver; Histidine; Insulin; Lipogene

2011
Changes in the extracellular profiles of neuroactive amino acids in the rat striatum at the asymptomatic stage of hepatic failure.
    Journal of neuroscience research, 1999, Apr-01, Volume: 56, Issue:1

    Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Biological Transport; Corpus Striatum; Excitatory Amin

1999
Evidence for a lesion in carbohydrate metabolism in fatty liver and kidney syndrome in chicks.
    Research in veterinary science, 1975, Volume: 18, Issue:2

    Topics: Alanine; Animals; Biotin; Carbohydrate Metabolism; Chickens; Fatty Liver; Fructosephosphates; Glucon

1975
Serum-albumin concentration and the onset of kwashiorkor.
    Lancet (London, England), 1973, Jan-13, Volume: 1, Issue:7794

    Topics: Alanine; Child; Deficiency Diseases; Fatty Liver; Growth Hormone; Humans; Hydrocortisone; Insulin; K

1973
Gluconeogenesis in the fatty liver of the rat: the effect of oleate and ethanol.
    The Journal of laboratory and clinical medicine, 1973, Volume: 82, Issue:3

    Topics: Acetoacetates; Alanine; Animals; Cytosol; Ethanol; Fatty Acids; Fatty Liver; Gluconeogenesis; Hydrox

1973
Hyperglucagonemia in Laennec's cirrhosis. The role of portal-systemic shunting.
    The New England journal of medicine, 1974, Jan-31, Volume: 290, Issue:5

    Topics: Adolescent; Adult; Aged; Alanine; Alcoholism; Amino Acids; Ammonia; Blood Glucose; Esophageal and Ga

1974
Alcohol hypoglycemia. VI. Interrelationships between the formation of glyceride-glycerol and glucose from alanine by liver slices.
    Metabolism: clinical and experimental, 1966, Volume: 15, Issue:11

    Topics: Alanine; Animals; Ethanol; Fatty Liver; Gluconeogenesis; Glycerides; Glycerol; Glycerophosphates; Hy

1966