alanine has been researched along with Fatty Liver, Nonalcoholic in 10 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This MR study elucidated the causal impact of lower birthweight on subsequent risk of NAFLD, independently of later-life adiposity and identified mediators including insulin resistance, branched-chain amino acids, alanine and MUFA in this association pathway." | 5.41 | Causal effect of lower birthweight on non-alcoholic fatty liver disease and mediating roles of insulin resistance and metabolites. ( Bi, Y; Chen, Y; Kong, L; Li, M; Lu, J; Ning, G; Wang, T; Wang, W; Wang, Y; Xu, M; Xu, Y; Ye, C; Zhao, Z; Zheng, J, 2023) |
| "The purpose of this study was to examine whether a Proline (Pro)-to-Alanine (Ala) exchange at codon 12 (Pro12Ala) polymorphism of the peroxisome proliferator-activated receptor-gamma (PPARγ) is associated with susceptibility to nonalcoholic fatty liver disease (NAFLD), rheumatoid arthritis (RA), and psoriatic arthritis (PsA)." | 4.90 | Meta-analysis of associations between the peroxisome proliferator-activated receptor-γ Pro12Ala polymorphism and susceptibility to nonalcoholic fatty liver disease, rheumatoid arthritis, and psoriatic arthritis. ( Bae, SC; Lee, YH; Song, GG, 2014) |
| " We hypothesised that the glucagon-alanine index, an indicator of the functional integrity of the liver-alpha cell axis, would associate with liver fat and insulin resistance in our cohort of women with low levels of liver fat." | 4.02 | The liver-alpha cell axis associates with liver fat and insulin resistance: a validation study in women with non-steatotic liver fat levels. ( Adamski, J; Gar, C; Haschka, SJ; Holst, JJ; Kern-Matschilles, S; Lechner, A; Prehn, C; Rauch, B; Sacco, V; Seissler, J; Wewer Albrechtsen, NJ, 2021) |
| " In addition, increased hepatic microvasculatures compliance-related improved buffering effect of portal vein to acute mannitol infusion was associated with decreased circulating nitric oxide and aldosterone, plasma volume expansion (dye dilution method), splanchnic blood pooling ((99 m) Tc-RBC SPECT/PET/CT scans), peripheral hypotension, portal hypertension and ascites in brivanib and sorafenib-treated NASH-cirrhotic rats." | 3.80 | Anti-VEGFR agents ameliorate hepatic venous dysregulation/microcirculatory dysfunction, splanchnic venous pooling and ascites of NASH-cirrhotic rat. ( Hsieh, YC; Huang, YT; Lee, FY; Lee, KC; Lee, PC; Lee, WP; Lin, HC; Liu, RS; Tan, TW; Yang, YY; Yeh, YC, 2014) |
| "Overall, patients with NAFLD and fibrosis had similar adiponectin concentrations with patients with NAFLD without fibrosis." | 2.82 | Circulating adiponectin in patients with nonalcoholic fatty liver disease-related liver fibrosis: A systematic review and a meta-analysis. ( Evripidou, K; Goulas, A; Goulis, DG; Makri, ES; Polyzos, SA; Tontikidou, C, 2022) |
| "In all, 32 subjects (11 patients with nonalcoholic steatohepatitis [NASH], 15 with simple steatosis [SS], and six healthy controls) were studied." | 1.46 | Hepatic Alanine Differentiates Nonalcoholic Steatohepatitis From Simple Steatosis in Humans and Mice: A Proton MR Spectroscopy Study With Long Echo Time. ( Cho, EY; Choi, KH; Jeong, YY; Jun, CH; Jun, HY; Kim, KJ; Kim, TH; Lee, MS; Lee, YH; Yoon, KH; Yun, KJ, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 6 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Atefi, M | 1 |
| Entezari, MH | 1 |
| Vahedi, H | 1 |
| Hassanzadeh, A | 1 |
| Tontikidou, C | 1 |
| Makri, ES | 1 |
| Evripidou, K | 1 |
| Goulis, DG | 1 |
| Goulas, A | 1 |
| Polyzos, SA | 1 |
| Kong, L | 1 |
| Ye, C | 1 |
| Wang, Y | 1 |
| Zheng, J | 1 |
| Zhao, Z | 1 |
| Li, M | 1 |
| Xu, Y | 1 |
| Lu, J | 1 |
| Chen, Y | 1 |
| Xu, M | 1 |
| Wang, W | 2 |
| Ning, G | 1 |
| Bi, Y | 1 |
| Wang, T | 1 |
| Zhang, L | 1 |
| Zi, L | 1 |
| Kuang, T | 1 |
| Wang, K | 1 |
| Qiu, Z | 1 |
| Wu, Z | 1 |
| Liu, L | 1 |
| Liu, R | 1 |
| Wang, P | 1 |
| Li, YN | 1 |
| Su, Y | 1 |
| Gar, C | 1 |
| Haschka, SJ | 1 |
| Kern-Matschilles, S | 1 |
| Rauch, B | 1 |
| Sacco, V | 1 |
| Prehn, C | 1 |
| Adamski, J | 1 |
| Seissler, J | 1 |
| Wewer Albrechtsen, NJ | 1 |
| Holst, JJ | 1 |
| Lechner, A | 1 |
| Yang, YY | 1 |
| Liu, RS | 1 |
| Lee, PC | 1 |
| Yeh, YC | 1 |
| Huang, YT | 1 |
| Lee, WP | 1 |
| Lee, KC | 1 |
| Hsieh, YC | 1 |
| Lee, FY | 1 |
| Tan, TW | 1 |
| Lin, HC | 1 |
| Lee, YH | 2 |
| Bae, SC | 1 |
| Song, GG | 1 |
| Duan, J | 1 |
| Merrill, AH | 1 |
| Kim, TH | 1 |
| Jun, HY | 1 |
| Kim, KJ | 1 |
| Lee, MS | 1 |
| Choi, KH | 1 |
| Yun, KJ | 1 |
| Jeong, YY | 1 |
| Jun, CH | 1 |
| Cho, EY | 1 |
| Yoon, KH | 1 |
4 reviews available for alanine and Fatty Liver, Nonalcoholic
| Article | Year |
|---|---|
Circulating adiponectin in patients with nonalcoholic fatty liver disease-related liver fibrosis: A systematic review and a meta-analysis.
Topics: Adiponectin; Adolescent; Adult; Alanine; Alanine Transaminase; Aspartate Aminotransferases; Child; H | 2022 |
Causal effect of lower birthweight on non-alcoholic fatty liver disease and mediating roles of insulin resistance and metabolites.
Topics: Adult; Alanine; Birth Weight; Child; Genome-Wide Association Study; Humans; Insulin Resistance; Isol | 2023 |
Meta-analysis of associations between the peroxisome proliferator-activated receptor-γ Pro12Ala polymorphism and susceptibility to nonalcoholic fatty liver disease, rheumatoid arthritis, and psoriatic arthritis.
Topics: Alanine; Arthritis, Psoriatic; Arthritis, Rheumatoid; Genetic Predisposition to Disease; Humans; Non | 2014 |
1-Deoxysphingolipids Encountered Exogenously and Made de Novo: Dangerous Mysteries inside an Enigma.
Topics: Alanine; Animals; Diabetes Mellitus; Humans; Lipids; Mutation; Non-alcoholic Fatty Liver Disease; Pe | 2015 |
1 trial available for alanine and Fatty Liver, Nonalcoholic
| Article | Year |
|---|---|
Sesame Oil Ameliorates Alanine Aminotransferase, Aspartate Aminotransferase, and Fatty Liver Grade in Women with Nonalcoholic Fatty Liver Disease Undergoing Low-Calorie Diet: A Randomized Double-Blind Controlled Trial.
Topics: Alanine; Alanine Transaminase; Aspartate Aminotransferases; Caloric Restriction; Diet, Reducing; Fem | 2022 |
5 other studies available for alanine and Fatty Liver, Nonalcoholic
| Article | Year |
|---|---|
Investigating causal associations among gut microbiota, metabolites, and liver diseases: a Mendelian randomization study.
Topics: Alanine; Clostridiales; Gastrointestinal Microbiome; Humans; Mendelian Randomization Analysis; Non-a | 2023 |
Remdesivir attenuates high fat diet (HFD)-induced NAFLD by regulating hepatocyte dyslipidemia and inflammation via the suppression of STING.
Topics: Adenosine Monophosphate; Administration, Oral; Alanine; Animals; Antiviral Agents; Diet, High-Fat; D | 2020 |
The liver-alpha cell axis associates with liver fat and insulin resistance: a validation study in women with non-steatotic liver fat levels.
Topics: Adiposity; Adult; Alanine; Biomarkers; Blood Chemical Analysis; Cross-Sectional Studies; Female; Glu | 2021 |
Anti-VEGFR agents ameliorate hepatic venous dysregulation/microcirculatory dysfunction, splanchnic venous pooling and ascites of NASH-cirrhotic rat.
Topics: Alanine; Animals; Ascites; Cytokines; DNA Primers; Fatty Liver; Fibroblast Growth Factors; Microcirc | 2014 |
Hepatic Alanine Differentiates Nonalcoholic Steatohepatitis From Simple Steatosis in Humans and Mice: A Proton MR Spectroscopy Study With Long Echo Time.
Topics: Adult; Alanine; Animals; Area Under Curve; Biopsy; Case-Control Studies; Fatty Liver; Female; Hepato | 2017 |