Page last updated: 2024-11-08

alanine and Experimental Hepatoma

alanine has been researched along with Experimental Hepatoma in 19 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
"2D DIGE and MS analyses were used to reveal proteomic signatures resulting from Notch3 inhibition in HepG2 cells, combined with brivanib treatment."1.51Brivanib in combination with Notch3 silencing shows potent activity in tumour models. ( Baglioni, M; Bolondi, L; D'Errico, A; Giannone, FA; Giovannini, C; Gramantieri, L; Salzano, AM; Scaloni, A; Svegliati Baroni, G; Vasuri, F; Vitale, M; Zambrano, N, 2019)
" Developing efficient nanodrugs could reduce the dosage and greatly improve the therapeutic effects in cancer treatments."1.46Amino acid functionalized gadofullerene nanoparticles with superior antitumor activity via destruction of tumor vasculature in vivo. ( Deng, R; Guan, M; Guo, J; Jia, W; Li, J; Li, X; Lu, Z; Shu, C; Sun, L; Wang, C; Yu, T; Zhang, Y; Zhen, M; Zhou, Y; Zou, T, 2017)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.79)18.7374
1990's9 (47.37)18.2507
2000's5 (26.32)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhou, Y1
Deng, R1
Zhen, M1
Li, J1
Guan, M1
Jia, W1
Li, X1
Zhang, Y1
Yu, T1
Zou, T1
Lu, Z1
Guo, J1
Sun, L1
Shu, C1
Wang, C1
Giovannini, C1
Salzano, AM1
Baglioni, M1
Vitale, M1
Scaloni, A1
Zambrano, N1
Giannone, FA1
Vasuri, F1
D'Errico, A1
Svegliati Baroni, G1
Bolondi, L1
Gramantieri, L1
Meijsing, B1
Carbó, N4
López-Soriano, FJ5
Argilés, JM5
Bukietyńska, K1
Podsiadly, H1
Karwecka, Z1
Christensen, HN1
Koch, MR1
Lea, MA1
Jones, JI1
Busby, WH1
Wright, G1
Clemmons, DR1
García-Martínez, C1
Ronen, SM1
Volk, A1
Mispelter, J1
Fiers, W1
Auguste, P1
Robledo, O1
Olivier, C1
Froger, J1
Praloran, V1
Pouplard-Barthelaix, A1
Gascan, H1
Lidofsky, SD1
Roman, RM2
Schlenker, T1
Feranchak, AP1
Schwake, L1
Stremmel, W1
Fitz, JG1
Busquets, S1
Alvarez, B1
van Royen, M1
Bink, H1
Felipe, A1
Gelehrter, TD1
Leonardi, MG2
Comolli, R2
Kovacević, Z1
Brkljac, O1
Bajin, K1
Giordana, B1

Reviews

1 review available for alanine and Experimental Hepatoma

ArticleYear
Glucocorticoids and the plasma membrane.
    Monographs on endocrinology, 1979, Volume: 12

    Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Cell Line; Cell Membrane

1979

Other Studies

18 other studies available for alanine and Experimental Hepatoma

ArticleYear
Amino acid functionalized gadofullerene nanoparticles with superior antitumor activity via destruction of tumor vasculature in vivo.
    Biomaterials, 2017, Volume: 133

    Topics: Alanine; Animals; Antinematodal Agents; Cell Line, Tumor; Female; Fullerenes; Gadolinium; Liver Neop

2017
Brivanib in combination with Notch3 silencing shows potent activity in tumour models.
    British journal of cancer, 2019, Volume: 120, Issue:6

    Topics: Alanine; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Resistance, Neoplasm; Electropho

2019
Effects of the phosphodiesterase-IV inhibitor EMD 95832/3 on tumour growth and cachexia in rats bearing the Yoshida AH-130 ascites hepatoma.
    Cancer letters, 2002, Dec-15, Volume: 188, Issue:1-2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Alanine; Animals; Blood Glucose; Cachexia; Cell

2002
Complexes of vanadium(III) with L-alanine and L-aspartic acid.
    Journal of inorganic biochemistry, 2003, Apr-01, Volume: 94, Issue:4

    Topics: Alanine; Animals; Antineoplastic Agents; Apoptosis; Aspartic Acid; Circular Dichroism; Hydrogen-Ion

2003
Hypothesis: control of hepatic utilization of alanine by membrane transport or by cellular metabolism? Review.
    Bioscience reports, 1983, Volume: 3, Issue:10

    Topics: Alanine; Alanine Transaminase; Amino Acids; Animals; Biological Transport; Caseins; Dietary Proteins

1983
Uptake of 14C-labeled dicarboxylic amino acids in hepatocytes and hepatoma cells.
    Cancer research, 1981, Volume: 41, Issue:8

    Topics: Alanine; Amino Acids; Amino Acids, Cyclic; Amino Acids, Dicarboxylic; Aminoisobutyric Acids; Animals

1981
Human IGFBP-1 is phosphorylated on 3 serine residues: effects of site-directed mutagenesis of the major phosphoserine.
    Growth regulation, 1993, Volume: 3, Issue:1

    Topics: Alanine; Amino Acid Sequence; Animals; Carrier Proteins; CHO Cells; Cricetinae; Humans; Insulin-Like

1993
Alanine metabolism in rats bearing the Yoshida AH-130 ascites hepatoma.
    Cancer letters, 1994, Dec-09, Volume: 87, Issue:2

    Topics: Alanine; Animals; Body Weight; Female; In Vitro Techniques; Liver Neoplasms, Experimental; Muscle Pr

1994
Comparative NMR study of a differentiated rat hepatoma and its dedifferentiated subclone cultured as spheroids and as implanted tumors.
    NMR in biomedicine, 1994, Volume: 7, Issue:6

    Topics: Alanine; Animals; Cell Differentiation; Cell Division; Energy Metabolism; Glucose; Glutamic Acid; La

1994
Tumour growth results in changes in placental amino acid transport in the rat: a tumour necrosis factor alpha-mediated effect.
    The Biochemical journal, 1996, Jan-01, Volume: 313 ( Pt 1)

    Topics: Alanine; Amino Acid Transport Systems; Amino Acids; Animals; Biological Transport; Carrier Proteins;

1996
Alanine substitution for Thr268 and Asp269 of soluble ciliary neurotrophic factor (CNTF) receptor alpha component defines a specific antagonist for the CNTF response.
    The Journal of biological chemistry, 1996, Oct-18, Volume: 271, Issue:42

    Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Binding, Competitive; Cell Division; Cell Line

1996
Alanine uptake activates hepatocellular chloride channels.
    The American journal of physiology, 1997, Volume: 273, Issue:4

    Topics: Alanine; Animals; Biological Transport; Chloride Channels; Intracellular Fluid; Kinetics; Liver Neop

1997
Functional interactions between oxidative stress, membrane Na(+) permeability, and cell volume in rat hepatoma cells.
    Gastroenterology, 2000, Volume: 118, Issue:2

    Topics: Alanine; Animals; Calcium; Catalase; Cell Membrane Permeability; Cell Size; Cytosol; D-Amino-Acid Ox

2000
Lack of effect of the cytokine suppressive agent FR167653 on tumour growth and cachexia in rats bearing the Yoshida AH-130 ascites hepatoma.
    Cancer letters, 2000, Aug-31, Volume: 157, Issue:1

    Topics: Adipose Tissue; Alanine; Animals; Anorexia; Blood Glucose; Cachexia; Cell Division; Female; Interleu

2000
Hepatic transport of gluconeogenic substrates during tumor growth in the rat.
    Cancer investigation, 2001, Volume: 19, Issue:3

    Topics: Alanine; Animals; Diffusion; Disease Progression; Female; Glucose; Glycerol; Kinetics; Lactic Acid;

2001
Changes in alanine transport in plasma membrane vesicles from rat liver during the early stages of diethylnitrosamine-induced hepatocarcinogenesis.
    Cancer letters, 1992, Jan-31, Volume: 61, Issue:3

    Topics: 2-Acetylaminofluorene; Alanine; Animals; Biological Transport; Cell Membrane; Diethylnitrosamine; He

1992
Control and function of the transamination pathways of glutamine oxidation in tumour cells.
    The Biochemical journal, 1991, Jan-15, Volume: 273(Pt 2)

    Topics: Alanine; Animals; Aspartic Acid; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Cell Membrane; Citr

1991
Alanine transport in plasma membrane vesicles from Yoshida ascites hepatoma cells (AH 130) in the exponential and stationary phase of growth.
    Cancer biochemistry biophysics, 1990, Volume: 11, Issue:4

    Topics: Alanine; Animals; Biological Transport; Carbon Radioisotopes; Cations, Monovalent; Cell Division; Ce

1990