Page last updated: 2024-11-08

alanine and Endotoxin Shock

alanine has been researched along with Endotoxin Shock in 18 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
" This study determined the effect of arginine on plasma glucose and insulin regulation during endotoxicosis in order to assess its contribution to glucose dyshomeostasis in the pathogenesis of endotoxin shock."3.66Insulin hypersecretion and potentiation of endotoxin shock in the rat. ( Filkins, JP; Yelich, MR, 1982)
" The association of hypoglycemia and increased arterial alanine and glycine with elevated plasma glucagon implied impaired gluconeogenesis."3.66Amino acid metabolism in dogs with E. coli bacteremic shock. ( Duff, JH; Groves, AC; Woolf, LI, 1979)
"Severe sepsis and septic shock syndromes were observed in 7 (53."1.56Clinical Characteristics and Outcomes of Hospitalized and Critically Ill Children and Adolescents with Coronavirus Disease 2019 at a Tertiary Care Medical Center in New York City. ( Aldrich, M; Cabana, MD; Chao, JY; Derespina, KR; Goldman, DL; Herold, BC; Medar, SS; Ushay, HM; Weingarten, J, 2020)
"Staphylococcus aureus superantigen toxic shock syndrome toxin-1 is a major cause of menstrual toxic shock syndrome."1.35Novel toxic shock syndrome toxin-1 amino acids required for biological activity. ( Amundson, WH; Brosnahan, AJ; Mantz, MJ; Peterson, ML; Schaefers, MM; Schlievert, PM; Squier, CA, 2008)
"In low-flow septic shock (CI, 1."1.26Proteolysis associated with a deficit of peripheral energy fuel substrates in septic man. ( Benotti, PN; Blackburn, GL; Clowes, GH; Miller, JD; O'Donnel, TF; Ryan, NT, 1976)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199010 (55.56)18.7374
1990's2 (11.11)18.2507
2000's3 (16.67)29.6817
2010's0 (0.00)24.3611
2020's3 (16.67)2.80

Authors

AuthorsStudies
Sanville, B1
Corbett, R1
Pidcock, W1
Hardin, K1
Sebat, C1
Nguyen, MV1
Thompson, GR1
Haczku, A1
Schivo, M1
Cohen, S1
Chao, JY1
Derespina, KR1
Herold, BC1
Goldman, DL1
Aldrich, M1
Weingarten, J1
Ushay, HM1
Cabana, MD1
Medar, SS1
Quintana-Ortega, C1
Remesal, A1
Ruiz de Valbuena, M1
de la Serna, O1
Laplaza-González, M1
Álvarez-Rojas, E1
Udaondo, C1
Alcobendas, R1
Murias, S1
Brosnahan, AJ1
Schaefers, MM1
Amundson, WH1
Mantz, MJ1
Squier, CA1
Peterson, ML1
Schlievert, PM1
Hu, J1
Dubois, V1
Chaltin, P1
Fiten, P1
Dillen, C1
Van den Steen, PE1
Opdenakker, G1
Yelich, MR1
Filkins, JP3
James, JH1
Fang, CH1
Schrantz, SJ1
Hasselgren, PO1
Paul, RJ1
Fischer, JE1
Hong, KW1
Kim, KE1
Rhim, BY1
Lee, WS1
Kim, CD1
Kiefer, P1
Tugtekin, I1
Wiedeck, H1
Vogt, J1
Wachter, U1
Bracht, H1
Geldner, G1
Georgieff, M1
Radermacher, P1
Clowes, GH2
Martin, H1
Walji, S1
Hirsch, E1
Gazitua, R1
Goodfellow, R1
Woolf, LI1
Groves, AC1
Duff, JH1
Kuttner, RE1
Spitzer, JJ1
O'Donnel, TF1
Blackburn, GL1
Ryan, NT1
Benotti, PN1
Miller, JD1
Metzler, B2
Rettenmeier, AW2
Wodarz, I1
Schmahl, FW2
Bauer, B1
Ishida, K1
Totsuka, M1
Hayasaka, H1
Cornell, RP1

Trials

1 trial available for alanine and Endotoxin Shock

ArticleYear
Effect of dopexamine on hepatic metabolic activity in patients with septic shock.
    Shock (Augusta, Ga.), 2001, Volume: 15, Issue:6

    Topics: Adult; Aged; Alanine; Blood Pressure; Dopamine; Female; Glucose; Glutamic Acid; Hemodynamics; Humans

2001

Other Studies

17 other studies available for alanine and Endotoxin Shock

ArticleYear
A Community-transmitted Case of Severe Acute Respiratory Distress Syndrome (SARS) Due to SARS-CoV-2 in the United States.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020, 11-19, Volume: 71, Issue:16

    Topics: Adenosine Monophosphate; Adult; Alanine; Antiviral Agents; Community-Acquired Infections; COVID-19;

2020
Clinical Characteristics and Outcomes of Hospitalized and Critically Ill Children and Adolescents with Coronavirus Disease 2019 at a Tertiary Care Medical Center in New York City.
    The Journal of pediatrics, 2020, Volume: 223

    Topics: Adenosine Monophosphate; Adolescent; Alanine; Antiviral Agents; Asthma; Betacoronavirus; Blood Urea

2020
Fatal outcome of anti-MDA5 juvenile dermatomyositis in a paediatric COVID-19 patient: a case report.
    Modern rheumatology case reports, 2021, Volume: 5, Issue:1

    Topics: Adenosine Monophosphate; Alanine; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Antivira

2021
Novel toxic shock syndrome toxin-1 amino acids required for biological activity.
    Biochemistry, 2008, Dec-09, Volume: 47, Issue:49

    Topics: Alanine; Amino Acids; Animals; Bacterial Toxins; Base Sequence; Binding Sites; Cell Membrane Permeab

2008
Inhibition of lethal endotoxin shock with an L-pyridylalanine containing metalloproteinase inhibitor selected by high-throughput screening of a new peptide library.
    Combinatorial chemistry & high throughput screening, 2006, Volume: 9, Issue:8

    Topics: ADAM Proteins; ADAM17 Protein; Alanine; Animals; Drug Evaluation, Preclinical; Enzyme Inhibitors; Ma

2006
Insulin hypersecretion and potentiation of endotoxin shock in the rat.
    Circulatory shock, 1982, Volume: 9, Issue:6

    Topics: Alanine; Animals; Arginine; Blood Glucose; Homeostasis; Hyperinsulinism; Insulin; Insulin Secretion;

1982
Linkage of aerobic glycolysis to sodium-potassium transport in rat skeletal muscle. Implications for increased muscle lactate production in sepsis.
    The Journal of clinical investigation, 1996, Nov-15, Volume: 98, Issue:10

    Topics: Aerobiosis; Alanine; Amino Acids; Animals; Dose-Response Relationship, Drug; Glucose; Glutamic Acid;

1996
Effect of rebamipide on liver damage and increased tumor necrosis factor in a rat model of endotoxin shock.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:9 Suppl

    Topics: Alanine; Animals; Disease Models, Animal; Enzyme Inhibitors; Escherichia coli; Lipopolysaccharides;

1998
Blood insulin responses to blood glucose levels in high output sepsis and spetic shock.
    American journal of surgery, 1978, Volume: 135, Issue:4

    Topics: Adult; Aged; Alanine; Blood Glucose; Cardiac Output; Escherichia coli Infections; Female; Glucose To

1978
Amino acid metabolism in dogs with E. coli bacteremic shock.
    Surgery, 1979, Volume: 85, Issue:2

    Topics: Alanine; Amino Acids; Animals; Blood Gas Analysis; Blood Pressure; Blood Urea Nitrogen; Dogs; Escher

1979
Gluconeogenesis from alanine in endotoxin-treated dogs.
    The Journal of surgical research, 1978, Volume: 25, Issue:2

    Topics: Alanine; Animals; Blood Glucose; Dogs; Gluconeogenesis; Lactates; Shock, Septic

1978
Proteolysis associated with a deficit of peripheral energy fuel substrates in septic man.
    Surgery, 1976, Volume: 80, Issue:2

    Topics: Adult; Aged; Alanine; Amino Acids; Blood Glucose; Energy Metabolism; Fatty Acids, Nonesterified; Fem

1976
Changes of serum amino acid concentrations in experimentally induced endotoxic shock. The significance of hyperalaninemia in the prediction of lethality.
    Progress in clinical and biological research, 1989, Volume: 308

    Topics: Alanine; Amino Acids; Animals; Gabexate; Guanidines; Male; Prognosis; Protease Inhibitors; Rabbits;

1989
Serum amino acids in experimentally induced endotoxic shock: the prognostic significance of hyperalaninemia.
    Circulatory shock, 1989, Volume: 29, Issue:1

    Topics: Alanine; Amino Acids; Animals; Endotoxins; Escherichia coli; Hematocrit; Hemoglobins; Kinetics; Male

1989
[Alanine metabolism in the skeletal muscle and plasma in endotoxemia].
    Nihon Geka Gakkai zasshi, 1985, Volume: 86, Issue:4

    Topics: Alanine; Animals; Glycine; Muscles; Proline; Rabbits; Sepsis; Shock, Septic

1985
Hypoglycemia and depressed hepatic gluconeogenesis during endotoxicosis in lead-sensitized rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 142, Issue:3

    Topics: Alanine; Animals; Blood Glucose; Endotoxins; Fructose; Gluconeogenesis; Hypoglycemia; Lactates; Lead

1973
Depression of hepatic gluconeogenesis and the hypoglycemia of endotoxin shock.
    The American journal of physiology, 1974, Volume: 227, Issue:4

    Topics: Alanine; Animals; Blood Glucose; Carbon Radioisotopes; Depression, Chemical; Endotoxins; Fasting; Gl

1974