Page last updated: 2024-11-08

alanine and Encephalopathy, Hepatic

alanine has been researched along with Encephalopathy, Hepatic in 14 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
"This study was to investigate the effects of ammonia and manganese in the metabolism of minimal hepatic encephalopathy (MHE)."8.31The interaction of ammonia and manganese in abnormal metabolism of minimal hepatic encephalopathy: A comparison metabolomics study. ( Li, Y; Liu, XF; Lu, JJ; Qiang, JW; Yang, XY, 2023)
"This study was to investigate the effects of ammonia and manganese in the metabolism of minimal hepatic encephalopathy (MHE)."4.31The interaction of ammonia and manganese in abnormal metabolism of minimal hepatic encephalopathy: A comparison metabolomics study. ( Li, Y; Liu, XF; Lu, JJ; Qiang, JW; Yang, XY, 2023)
"Rats were treated with a hepatotoxin thioacetamide (TAA) and examined 21 days later, when they showed moderate fatty metamorphosis of the liver and morphological changes in brain indicative of excitotoxic neuronal damage, but no evident biochemical or neurophysiological symptoms of hepatic encephalopathy (HE)."3.70Changes in the extracellular profiles of neuroactive amino acids in the rat striatum at the asymptomatic stage of hepatic failure. ( Albrecht, J; Borkowska, HD; Gadamski, R; Hilgier, W; Oja, SS; Saransaari, P; Walski, M; Zielińska, M, 1999)
"Myo-inositol levels were strongly decreased already at 3h after treatment with NH4Cl; other intracellular osmolytes, such as hypotaurine and choline-containing compounds were also decreased, along with a concomitant increase of both the total concentration and the amount of newly synthesized glutamine, alanine, and glutathione."1.33Ammonia toxicity under hyponatremic conditions in astrocytes: de novo synthesis of amino acids for the osmoregulatory response. ( Leibfritz, D; Zwingmann, C, 2005)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's6 (42.86)18.2507
2000's2 (14.29)29.6817
2010's0 (0.00)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Liu, XF2
Lu, JJ2
Li, Y2
Yang, XY2
Qiang, JW2
Holt, DE1
Washabau, RJ1
Djali, S1
Dayrell-Hart, B1
Drobatz, KJ1
Heyes, MP1
Robinson, MB1
VISAKORPI, JK1
WASZ-HOECKERT, O1
TOERMAE, T1
MONDEN, M1
Zwingmann, C1
Leibfritz, D1
Rao, VL1
Audet, RM1
Butterworth, RF2
Dejong, CH1
Deutz, NE1
Soeters, PB1
Marchesini, G1
Fabbri, A1
Bianchi, G1
Brizi, M1
Zoli, M1
Michalak, A1
Hilgier, W1
Zielińska, M1
Borkowska, HD1
Gadamski, R1
Walski, M1
Oja, SS1
Saransaari, P1
Albrecht, J1
Ganda, OP1
Ruderman, NB1
Fiaccadori, F1
Pedretti, G1
Ferrari, C1
Pizzaferri, P1
Riggio, O1
Orlandi, N1
Pezzarossa, A1
Buxton, BH1
Stewart, DA1
Murray-Lyon, IM1
Curzon, G1
Williams, R1

Other Studies

14 other studies available for alanine and Encephalopathy, Hepatic

ArticleYear
Oral magnesium sulphate administration in rats with minimal hepatic encephalopathy: NMR-based metabolic characterization of the brain
    Magnesium research, 2022, 04-01, Volume: 35, Issue:2

    Topics: Administration, Oral; Alanine; Animals; Aspartic Acid; Brain; Glutamates; Hepatic Encephalopathy; Ma

2022
The interaction of ammonia and manganese in abnormal metabolism of minimal hepatic encephalopathy: A comparison metabolomics study.
    PloS one, 2023, Volume: 18, Issue:8

    Topics: Alanine; Ammonia; Animals; Arginine; Brain; Citrulline; gamma-Aminobutyric Acid; Glutamic Acid; Glut

2023
Cerebrospinal fluid glutamine, tryptophan, and tryptophan metabolite concentrations in dogs with portosystemic shunts.
    American journal of veterinary research, 2002, Volume: 63, Issue:8

    Topics: Alanine; Animals; Dietary Proteins; Dog Diseases; Dogs; Female; Glutamine; Hepatic Encephalopathy; H

2002
THE AMINO ACIDS OF CEREBROSPINAL FLUID IN VARIOUS DISEASES AFFECTING THE CENTRAL NERVOUS SYSTEM.
    Annales paediatriae Fenniae, 1964, Volume: 10

    Topics: Adolescent; Alanine; Amino Acids; Autistic Disorder; Brain Neoplasms; Cerebrospinal Fluid; Child; En

1964
[A STUDY OF THE FREE AMINO ACIDS IN THE SERUM OF LIVER DISEASES].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1964, May-10, Volume: 53

    Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Blood; Carbon Tetrachloride; Chemical and Drug Ind

1964
Ammonia toxicity under hyponatremic conditions in astrocytes: de novo synthesis of amino acids for the osmoregulatory response.
    Neurochemistry international, 2005, Volume: 47, Issue:1-2

    Topics: Alanine; Amino Acids; Ammonia; Ammonium Chloride; Animals; Animals, Newborn; Astrocytes; Brain Edema

2005
Selective alterations of extracellular brain amino acids in relation to function in experimental portal-systemic encephalopathy: results of an in vivo microdialysis study.
    Journal of neurochemistry, 1995, Volume: 65, Issue:3

    Topics: Acetates; Alanine; Amino Acids; Animals; Brain; Dialysis; Extracellular Space; Frontal Lobe; Glutami

1995
Intestinal glutamine and ammonia metabolism during chronic hyperammonaemia induced by liver insufficiency.
    Gut, 1993, Volume: 34, Issue:8

    Topics: Alanine; Ammonia; Animals; Bile Ducts; Blood Flow Velocity; Body Weight; Chronic Disease; Citrulline

1993
Zinc supplementation and amino acid-nitrogen metabolism in patients with advanced cirrhosis.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:5

    Topics: Administration, Oral; Adult; Aged; Alanine; Ammonia; Female; Glucagon; Hepatic Encephalopathy; Human

1996
Selective loss of binding sites for the glutamate receptor ligands [3H]kainate and (S)-[3H]5-fluorowillardiine in the brains of rats with acute liver failure.
    Hepatology (Baltimore, Md.), 1997, Volume: 25, Issue:3

    Topics: Alanine; Animals; Binding Sites; Brain; Cerebellum; Cerebral Cortex; Dizocilpine Maleate; Hepatic En

1997
Changes in the extracellular profiles of neuroactive amino acids in the rat striatum at the asymptomatic stage of hepatic failure.
    Journal of neuroscience research, 1999, Apr-01, Volume: 56, Issue:1

    Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Biological Transport; Corpus Striatum; Excitatory Amin

1999
Muscle nitrogen metabolism in chronic hepatic insufficiency.
    Metabolism: clinical and experimental, 1976, Volume: 25, Issue:4

    Topics: Adult; Aged; Alanine; Alcoholism; Amino Acids; Ammonia; Brachial Artery; Female; Forearm; Glutamine;

1976
Insulin and glucagon levels in fulminant hepatic failure in man.
    Digestive diseases and sciences, 1991, Volume: 36, Issue:6

    Topics: Adult; Alanine; alpha-Fetoproteins; Amino Acids, Branched-Chain; Blood Glucose; C-Peptide; Female; G

1991
Plasma amino acids in experimental acute hepatic failure and their relationship to brain tryptophan.
    Clinical science and molecular medicine, 1974, Volume: 46, Issue:4

    Topics: Acute Disease; Alanine; Amino Acids; Animals; Brain Chemistry; Disease Models, Animal; Glycine; Hepa

1974