alanine has been researched along with Down Syndrome in 5 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (20.00) | 18.7374 |
1990's | 1 (20.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 2 (40.00) | 2.80 |
Authors | Studies |
---|---|
Rodriguez, Z | 1 |
Shane, AL | 1 |
Verkerke, H | 1 |
Lough, C | 1 |
Zimmerman, MG | 1 |
Suthar, M | 1 |
Wrammert, J | 1 |
MacDonald, H | 1 |
Wolf, M | 1 |
Clarke, S | 1 |
Roback, JD | 1 |
Arthur, CM | 1 |
Stowell, SR | 1 |
Josephson, CD | 1 |
Kim-Hellmuth, S | 1 |
Hermann, M | 1 |
Eilenberger, J | 1 |
Ley-Zaporozhan, J | 1 |
Fischer, M | 1 |
Hauck, F | 1 |
Klein, C | 1 |
Haas, N | 1 |
Kappler, M | 1 |
Huebner, J | 1 |
Jakob, A | 1 |
von Both, U | 1 |
Rosenberg, RN | 1 |
Yao, FS | 1 |
Caserta, MT | 1 |
Wyrwicz, AM | 1 |
1 review available for alanine and Down Syndrome
Article | Year |
---|---|
A causal role for amyloid in Alzheimer's disease: the end of the beginning.
Topics: Alanine; Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Amyloid beta-Protein Precurs | 1993 |
4 other studies available for alanine and Down Syndrome
Article | Year |
---|---|
COVID-19 convalescent plasma clears SARS-CoV-2 refractory to remdesivir in an infant with congenital heart disease.
Topics: Adenosine Monophosphate; Alanine; Antibodies, Neutralizing; Antiviral Agents; Coronavirus Infections | 2020 |
SARS-CoV-2 Triggering Severe Acute Respiratory Distress Syndrome and Secondary Hemophagocytic Lymphohistiocytosis in a 3-Year-Old Child With Down Syndrome.
Topics: Adenosine Monophosphate; Alanine; Antiviral Agents; Child, Preschool; COVID-19; COVID-19 Drug Treatm | 2021 |
In vitro 1H and 31P NMR spectroscopic evidence of multiple aberrant biochemical pathways in murine trisomy 16 brain development.
Topics: Alanine; Animals; Aspartic Acid; Biomarkers; Brain Chemistry; Choline; Creatine; Disease Models, Ani | 2000 |
Genetic causes of mental subnormality.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Aneuploidy; Chromosome Aberrations; Chromosome Disord | 1973 |